German Diabetes Center

Key research areas

  • Development and evaluation of diabetes – guidelines, training programmes and online information services
  • Epidemiology of diabetic complications
  • Immunology of diabetes, arteriosclerosis, obesity and nutrition
  • Molecular mechanisms of signal transduction and the role of gene regulation with respect to insulin resistence and insulin secretion.
  • Regulation of inflammatory processes with diabetes mellitus


Scientific Director:
Prof. Dr. Michael Roden
Telefon +49(0) 211-33 82-201
Fax +49(0) 211-33 82-691
E-Mail: michael.roden@ddz.uni-duesseldorf.de

The German Diabetes Center (DDZ) incorporates three scientific institutes, the Institute for Clinical Diabetology, the Institute for Clinical Biochemistry and Pathobiochemistry and the Institute for Biometry and Epidemiology. These collaborate closely together to carry out research on diabetes mellitus.

The German Diabetes Center – an institute of the Leibniz Association – is an institution that works at such a national level to study and treat diabetes. The German Diabetes Center receives half of its institutional sponsorship from the federal government, and the other half from the state of North Rhine Westphalia. Specific projects are also funded by extensive private funds received from the German Research Council, the European Union, the Federal Ministry of Research and Development, the Federal Ministry of Health, regional ministries, foundations and other private organisations. The German Diabetes Center presently employs around 190 members of staff.

The scientific director of the institute is a member of the medical faculty, Prof. Michael Roden also hold a chair at the Heinrich Heine University.

Research

 Diabetes mellitus comprises heterogeneous metabolic disorders which are characterized by hyperglycemia. Various factors contribute to the pathogenesis and development of these disorders.
Identification of these factors and integration into pathophysiological concepts are key to novel therapeutic approaches to diabetes mellitus including prediabetic states and associated diseases.
Researchers of six Research Groups and the staff unit "Technical Lab" of the Institute for Clinical Diabetology study the mechanisms of the natural course of LADA, Type 1 or Type 2 diabetes and perform studies on the prevention, novel forms of treatment of diabetes and its late complications.

The Institute for Clinical Biochemistry and Pathobiochemistry is lead by Professor Dr. Hadi Al-Hasani and investigates the molecular basis of onset and progression of obesity, insulin resistance and type&nbdp;2 diabetes. Our aim is to gain insights that may lead to improvements in prevention, prediction and therapy of diabetes.

The Institute for Biometrics and Epidemiology conducts population-based studies on the descriptive epidemiology of the two types of diabetes and its complications to improve prevention and early detection, as well as medical care of patients with diabetes.
Analytical epidemiological studies are focused on the detection of Public Health- related risk factors of diabetes. These studies are carried out in close cooperation with other national and international epidemiological centers, clinical partners and basic scientists. The studies are conducted in accordance to international epidemiological standards. The Institute also contributes to the further development of biometrical-epidemiological methods.
The Institute of Biometrics and Epidemiology at the German Diabetes Center is the only institution in Germany, which sees its main objective in creating up-to- date epidemiological data on diabetes.

Patient care

Under the leadership of Prof. Michael Roden, the Institute for Clinical Diabetology is responsible for outpatient and inpatient care as well as clinical research into diabetes mellitus. The most up to date methods and technology are available for this.