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Seahorse XFe96 Analyzer as part of the 'Cellular Metabolism Platform' is ready to use !

For details see here

 

 

Stellenangebote

 

Wir suchen

(Bio-)Informatiker/in; Fach-Informatiker/in; IT-Systemadministrator/in 

 

außerdem sind Initiativbewerbungen erwünscht für

Post-Doc mit Erfahrungen im Arbeiten mit Saccharomyces cerevisiae (Thema: Regulation der Mitophagie)

 

Neue Veröffentlichungen ab 2015

2017

SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy.

Lang A, Anand R, Altinoluk-Hambüchen S, Ezzahoini H, Stefanski A, Iram A, Bergmann L, Urbach J, Böhler P, Hänsel J, Franke M, Stühler K, Krutmann J, Scheller J, Stork B, Reichert AS, Piekorz RP.

Aging (Albany NY). 2017 Oct 29. doi: 10.18632/aging.101307. [Epub ahead of print]

 

How to get rid of mitochondria: crosstalk and regulation of multiple mitophagy pathways.

Zimmermann M, Reichert AS.

Biol Chem. 2017 Sep 26. pii: /j/bchm.just-accepted/hsz-2017-0206/hsz-2017-0206.xml. doi: 10.1515/hsz-2017-0206. [Epub ahead of print]

 

Cristae architecture is determined by an interplay of the MICOS complex and the F1FO ATP synthase via Mic27 and Mic10

Eydt K, Davies KM, Behrendt C, Wittig I, Reichert AS.

Microb Cell. 2017 Jul 20;4(8):259-272. doi: 10.15698/mic2017.08.585

 

Modulation of oxidative phosphorylation and redox homeostasis in mitochondrial NDUFS4 deficiency via mesenchymal stem cells

Melcher M, Danhauser K, Seibt A, Degistirici Ö, Baertling F, Kondadi AK, Reichert AS, Koopman WJH, Willems PHGM, Rodenburg RJ, Mayatepek E, Meisel R, Distelmaier F.

Stem Cell Res Ther. 2017 Jun 24;8(1):150. doi: 10.1186/s13287-017-0601-7

 

2016

OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation.

Barrera M, Koob S, Dikov D, Vogel F, Reichert AS.

FEBS Lett. 2016 Sep 1. doi: 10.1002/1873-3468.12384. [Epub ahead of print]

 

Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells

Ruchika Anand, Valentina Strecker, Jennifer Urbach, Ilka Wittig, Andreas S. Reichert

Research Article | published 01 Aug 2016 PLOS ONE

 

 

Controlling quality and amount of mitochondria by mitophagy: insights into the role of ubiquitination and deubiquitination.

Tan T, Zimmermann M, Reichert AS.

Biol Chem. 2016 Jul 1;397(7):637-47. doi: 10.1515/hsz-2016-0125.

 

 

2015

Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma are highly dependent on oxidative phosphorylation. Birkenmeier K, Dröse S, Wittig I, Winkelmann R, Käfer V, Döring C, Hartmann S, Wenz T, Reichert AS, Brandt U, Hansmann ML.Int J Cancer. 2015 Nov 23. doi: 10.1002/ijc.29934. [Epub ahead of print]; PMID:26595876

 

Data supporting the role of the non-glycosylated isoform of MIC26 in determining cristae morphology

Link to Elsevier article Koob et al. 2015

 

Mitophagy and deubiquitination in yeast - the power of synthetic quantitative array technology

Link to Molecular & Cellular Oncology article Behrendt et al. 2015

 

The Redox Code

Link to Antioxid Redox Signal article Jones et al. 2015

 

The non-glycosylated isoform of MIC26 is a constituent of the mammalian MICOS complex and promotes formation of crista junctions

Link to Biochimica et Biophysica Acta article Koob et al. 2015

 

Mitophagy and mitochondrial dynamics in Saccharomyces cerevisiae

Link to Biochimica et Biophysica Acta article Müller et al. 2015

 

Synthetic Quantitative Array Technology Identifies the Ubp3-Bre5 Deubiquitinase Complex as a Negative Regulator of Mitophagy

We have developed a method, termed synthetic quantitative array technology, to screen for mitophagy modulators in yeast. Using this method we identified the Ubp3-Bre5 deubiquitination complex, which inhibits mitophagy but promotes other types of autophagy. Deubiquitination thus appears to regulate a switch between distinct autophagy pathways.

Link to Cell Reports article Müller et al. 2015

 

Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan

We show that balanced mitochondrial dynamics and not a filamentous mitochondrial morphotype per se plays a key factor for ensuring long lifespan. Our study demonstrates a cross-talk between two different mitochondrial quality control pathways: mitophagy and mitochondrial dynamics.

Link to Scientific Reports article Bernhard et al. 2015

 

 

 
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