Publications Group Sies

 

 

Jones, D. P., Sies, H. (2015). "The Redox Code". Antioxid Redox Signal. PMID 25891126

Dkhil, M. A., A. A. Abdel-Baki, F. Wunderlich, H. Sies and S. Al-Quraishy (2014). "Dietary selenium affects intestinal development of Eimeria papillata in mice." Parasitol Res 113(1): 267-274. PMID: 24221886

Mano, C. M., F. M. Prado, J. Massari, G. E. Ronsein, G. R. Martinez, S. Miyamoto, J. Cadet, H. Sies, M. H. Medeiros, E. J. Bechara and P. Di Mascio (2014). "Excited singlet molecular O2 ((1)Deltag) is generated enzymatically from excited carbonyls in the dark." Sci Rep 4: 5938. PMID: 25087485

Pompella, A., H. Sies, R. Wacker, F. Brouns, T. Grune, H. K. Biesalski and J. Frank (2014). "The use of total antioxidant capacity as surrogate marker for food quality and its effect on health is to be discouraged." Nutrition 30(7-8): 791-793. PMID: 24984994

Rajalin, A. M., M. Micoogullari, H. Sies and H. Steinbrenner (2014). "Upregulation of the thioredoxin-dependent redox system during differentiation of 3T3-L1 cells to adipocytes." Biol Chem 395(6): 667-677. PMID: 24516001

Sies, H. (2014). "Role of metabolic H2O2 generation: redox signaling and oxidative stress." J Biol Chem 289(13): 8735-8741. PMID: 24515117

Speckmann, B., H. J. Bidmon, A. Borchardt, H. Sies and H. Steinbrenner (2014). "Intestinal selenoprotein P in epithelial cells and in plasma cells." Arch Biochem Biophys 541: 30-36. PMID: 24157689

Terao, J. and H. Sies (2014). "Special issue "polyphenols and health"." Arch Biochem Biophys 559: 1-2. PMID: 24953178

Blumberg, J. B., T. A. Camesano, A. Cassidy, P. Kris-Etherton, A. Howell, C. Manach, L. M. Ostertag, H. Sies, A. Skulas-Ray and J. A. Vita (2013). "Cranberries and their bioactive constituents in human health." Adv Nutr 4(6): 618-632. PMID: 24228191

Haussinger, D. and H. Sies (2013). "Hepatic encephalopathy: clinical aspects and pathogenetic concept." Arch Biochem Biophys 536(2): 97-100. PMID: 23643660

Parnham, M. J. and H. Sies (2013). "The early research and development of ebselen." Biochem Pharmacol 86(9): 1248-1253. PMID: 24012716

Steinbrenner, H., A. L. Hotze, B. Speckmann, A. Pinto, H. Sies, M. Schott, M. Ehlers, W. A. Scherbaum and S. Schinner (2013). "Localization and regulation of pancreatic selenoprotein P." J Mol Endocrinol 50(1): 31-42. PMID: 23125459

Steinbrenner, H. and H. Sies (2013). "Selenium homeostasis and antioxidant selenoproteins in brain: implications for disorders in the central nervous system." Arch Biochem Biophys 536(2): 152-157. PMID: 23500141

Steinbrenner, H., B. Speckmann and H. Sies (2013). "Toward understanding success and failures in the use of selenium for cancer prevention." Antioxid Redox Signal 19(2): 181-191. PMID: 23421468

von Lintig, J. and H. Sies (2013). "Carotenoids." Arch Biochem Biophys 539(2): 99-101. PMID: 24076362

Chapple, I. L., M. R. Milward, N. Ling-Mountford, P. Weston, K. Carter, K. Askey, G. E. Dallal, S. De Spirt, H. Sies, D. Patel and J. B. Matthews (2012). "Adjunctive daily supplementation with encapsulated fruit, vegetable and berry juice powder concentrates and clinical periodontal outcomes: a double-blind RCT." J Clin Periodontol 39(1): 62-72. PMID: 22093005

De Spirt, S., H. Sies, H. Tronnier and U. Heinrich (2012). "An encapsulated fruit and vegetable juice concentrate increases skin microcirculation in healthy women." Skin Pharmacol Physiol 25(1): 2-8. PMID: 21822034

Pinto, A., D. T. Juniper, M. Sanil, L. Morgan, L. Clark, H. Sies, M. P. Rayman and H. Steinbrenner (2012). "Supranutritional selenium induces alterations in molecular targets related to energy metabolism in skeletal muscle and visceral adipose tissue of pigs." J Inorg Biochem 114: 47-54. PMID: 22694857

Sies, H., P. C. Hollman, T. Grune, W. Stahl, H. K. Biesalski and G. Williamson (2012). "Protection by flavanol-rich foods against vascular dysfunction and oxidative damage: 27th Hohenheim Consensus Conference." Adv Nutr 3(2): 217-221. PMID: 22516731

Stahl, W. and H. Sies (2012). "beta-Carotene and other carotenoids in protection from sunlight." Am J Clin Nutr 96(5): 1179S-1184S. PMID: 23053552

Stahl, W. and H. Sies (2012). "Photoprotection by dietary carotenoids: concept, mechanisms, evidence and future development." Mol Nutr Food Res 56(2): 287-295. PMID: 21953695

Al-Quraishy, S., D. Delic, H. Sies, F. Wunderlich, A. A. Abdel-Baki and M. A. Dkhil (2011). "Differential miRNA expression in the mouse jejunum during garlic treatment of Eimeria papillata infections." Parasitol Res 109(2): 387-394. PMID: 21301871

Brossette, T., C. Hundsdorfer, K. D. Kroncke, H. Sies and W. Stahl (2011). "Direct evidence that (-)-epicatechin increases nitric oxide levels in human endothelial cells." Eur J Nutr 50(7): 595-599. PMID: 21327831

Dkhil, M., A. A. Abdel-Baki, D. Delic, F. Wunderlich, H. Sies and S. Al-Quraishy (2011). "Eimeria papillata: upregulation of specific miRNA-species in the mouse jejunum." Exp Parasitol 127(2): 581-586. PMID: 21093440

Dkhil, M. A., A. S. Abdel-Baki, F. Wunderlich, H. Sies and S. Al-Quraishy (2011). "Anticoccidial and antiinflammatory activity of garlic in murine Eimeria papillata infections." Vet Parasitol 175(1-2): 66-72. PMID: 20943319

Erhardt, A., W. Stahl, H. Sies, F. Lirussi, A. Donner and D. Haussinger (2011). "Plasma levels of vitamin E and carotenoids are decreased in patients with Nonalcoholic Steatohepatitis (NASH)." Eur J Med Res 16(2): 76-78. PMID: 21463986

Hollman, P. C., A. Cassidy, B. Comte, M. Heinonen, M. Richelle, E. Richling, M. Serafini, A. Scalbert, H. Sies and S. Vidry (2011). "The biological relevance of direct antioxidant effects of polyphenols for cardiovascular health in humans is not established." J Nutr 141(5): 989S-1009S. PMID: 21451125

Pinto, A., B. Speckmann, M. Heisler, H. Sies and H. Steinbrenner (2011). "Delaying of insulin signal transduction in skeletal muscle cells by selenium compounds." J Inorg Biochem 105(6): 812-820. PMID: 21497580

Sies, H. (2011). "Tribute to Professor Minor J. Coon." Arch Biochem Biophys 507(1): 3. PMID: 21324388

Sies, H. (2011). "Use of isolated liver perfusion in metabolic studies: ground-laying work in experimental hepatology." Z Gastroenterol 49(6): 737-739. PMID: 21638240

Speckmann, B., H. J. Bidmon, A. Pinto, M. Anlauf, H. Sies and H. Steinbrenner (2011). "Induction of glutathione peroxidase 4 expression during enterocytic cell differentiation." J Biol Chem 286(12): 10764-10772. PMID: 21252226

Steinbrenner, H., B. Speckmann, A. Pinto and H. Sies (2011). "High selenium intake and increased diabetes risk: experimental evidence for interplay between selenium and carbohydrate metabolism." J Clin Biochem Nutr 48(1): 40-45. PMID: 21297910

Bartholome, A., A. Kampkotter, S. Tanner, H. Sies and L. O. Klotz (2010). "Epigallocatechin gallate-induced modulation of FoxO signaling in mammalian cells and C. elegans: FoxO stimulation is masked via PI3K/Akt activation by hydrogen peroxide formed in cell culture." Arch Biochem Biophys 501(1): 58-64. PMID: 20513639

Li, L., R. S. Willets, M. C. Polidori, W. Stahl, G. Nelles, H. Sies and H. R. Griffiths (2010). "Oxidative LDL modification is increased in vascular dementia and is inversely associated with cognitive performance." Free Radic Res 44(3): 241-248. PMID: 20166891

Pirev, E., Y. Ince, H. Sies and K. D. Kroncke (2010). "Heat shock but not cold shock leads to disturbed intracellular zinc homeostasis." J Cell Physiol 223(1): 103-109. PMID: 20039271

Sies, H. (2010). "Polyphenols and health: update and perspectives." Arch Biochem Biophys 501(1): 2-5. PMID: 20398620

Speckmann, B., A. Pinto, M. Winter, I. Forster, H. Sies and H. Steinbrenner (2010). "Proinflammatory cytokines down-regulate intestinal selenoprotein P biosynthesis via NOS2 induction." Free Radic Biol Med 49(5): 777-785. PMID: 20542496

Ale-Agha, N., S. Galban, C. Sobieroy, K. Abdelmohsen, M. Gorospe, H. Sies and L. O. Klotz (2009). "HuR regulates gap junctional intercellular communication by controlling beta-catenin levels and adherens junction integrity." Hepatology 50(5): 1567-1576. PMID: 19676129

Camera, E., A. Mastrofrancesco, C. Fabbri, F. Daubrawa, M. Picardo, H. Sies and W. Stahl (2009). "Astaxanthin, canthaxanthin and beta-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-responsive enzymes." Exp Dermatol 18(3): 222-231. PMID: 18803658

De Spirt, S., W. Stahl, H. Tronnier, H. Sies, M. Bejot, J. M. Maurette and U. Heinrich (2009). "Intervention with flaxseed and borage oil supplements modulates skin condition in women." Br J Nutr 101(3): 440-445. PMID: 18761778

Haussinger, D. and H. Sies (2009). "Highlight: 'regenerative hepatology'." Biol Chem 390(10): 949-950. PMID: 19764897

Polidori, M. C., J. C. Carrillo, P. E. Verde, H. Sies, J. Siegrist and W. Stahl (2009). "Plasma micronutrient status is improved after a 3-month dietary intervention with 5 daily portions of fruits and vegetables: implications for optimal antioxidant levels." Nutr J 8: 10. PMID: 19208246

Polidori, M. C., D. Pratico, F. Mangialasche, E. Mariani, O. Aust, T. Anlasik, N. Mang, L. Pientka, W. Stahl, H. Sies, P. Mecocci and G. Nelles (2009). "High fruit and vegetable intake is positively correlated with antioxidant status and cognitive performance in healthy subjects." J Alzheimers Dis 17(4): 921-927. PMID: 19542607

Sies, H. (2009). "Highlight: molecular and cellular mechanisms of memory." Biol Chem 390(11): 1085. PMID: 19803817

Speckmann, B., H. Sies and H. Steinbrenner (2009). "Attenuation of hepatic expression and secretion of selenoprotein P by metformin." Biochem Biophys Res Commun 387(1): 158-163. PMID: 19576170

Steinbrenner, H. and H. Sies (2009). "Protection against reactive oxygen species by selenoproteins." Biochim Biophys Acta 1790(11): 1478-1485. PMID: 19268692

Williamson, G., H. Sies, D. Heber, C. L. Keen, I. A. Macdonald, L. Actis-Goretta, T. Y. Momma, J. I. Ottaviani, R. R. Holt, H. Schroeter and C. Heiss (2009). "Functional foods for health promotion: state-of-the-science on dietary flavonoids. Extended abstracts from the 12th Annual Conference on Functional Foods for Health Promotion, April 2009." Nutr Rev 67(12): 736-743. PMID: 19941619

Bellei, B., A. Mastrofrancesco, S. Briganti, N. Aspite, N. Ale-Agha, H. Sies and M. Picardo (2008). "Ultraviolet A induced modulation of gap junctional intercellular communication by P38 MAPK activation in human keratinocytes." Exp Dermatol 17(2): 115-124. PMID: 18047584

Pirev, E., C. Calles, P. Schroeder, H. Sies and K. D. Kroncke (2008). "Ultraviolet-A irradiation but not ultraviolet-B or infrared-A irradiation leads to a disturbed zinc homeostasis in cells." Free Radic Biol Med 45(1): 86-91. PMID: 18454944

Schewe, T., Y. Steffen and H. Sies (2008). "How do dietary flavanols improve vascular function? A position paper." Arch Biochem Biophys 476(2): 102-106. PMID: 18358827

Schnorr, O., T. Brossette, T. Y. Momma, P. Kleinbongard, C. L. Keen, H. Schroeter and H. Sies (2008). "Cocoa flavanols lower vascular arginase activity in human endothelial cells in vitro and in erythrocytes in vivo." Arch Biochem Biophys 476(2): 211-215. PMID: 18348861

Spalteholz, H., P. G. Furtmuller, C. Jakopitsch, C. Obinger, T. Schewe, H. Sies and J. Arnhold (2008). "Kinetic evidence for rapid oxidation of (-)-epicatechin by human myeloperoxidase." Biochem Biophys Res Commun 371(4): 810-813. PMID: 18466756

Speckmann, B., P. L. Walter, L. Alili, R. Reinehr, H. Sies, L. O. Klotz and H. Steinbrenner (2008). "Selenoprotein P expression is controlled through interaction of the coactivator PGC-1alpha with FoxO1a and hepatocyte nuclear factor 4alpha transcription factors." Hepatology 48(6): 1998-2006. PMID: 18972406

Steffen, Y., C. Gruber, T. Schewe and H. Sies (2008). "Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase." Arch Biochem Biophys 469(2): 209-219. PMID: 17996190

Werth, C., D. Stuhlmann, B. Cat, H. Steinbrenner, L. Alili, H. Sies and P. Brenneisen (2008). "Stromal resistance of fibroblasts against oxidative damage: involvement of tumor cell-secreted platelet-derived growth factor (PDGF) and phosphoinositide 3-kinase (PI3K) activation." Carcinogenesis 29(2): 404-410. PMID: 18174235

Abdelmohsen, K., E. Sauerbier, N. Ale-Agha, J. Beier, P. Walter, S. Galban, D. Stuhlmann, H. Sies and L. O. Klotz (2007). "Epidermal growth factor- and stress-induced loss of gap junctional communication is mediated by ERK-1/ERK-2 but not ERK-5 in rat liver epithelial cells." Biochem Biophys Res Commun 364(2): 313-317. PMID: 17945186

Cronauer, M. V., Y. Ince, R. Engers, L. Rinnab, W. Weidemann, C. V. Suschek, M. Burchardt, H. Kleinert, J. Wiedenmann, H. Sies, R. Ackermann and K. D. Kroncke (2007). "Nitric oxide-mediated inhibition of androgen receptor activity: possible implications for prostate cancer progression." Oncogene 26(13): 1875-1884. PMID: 16983333

Heiss, C., D. Finis, P. Kleinbongard, A. Hoffmann, T. Rassaf, M. Kelm and H. Sies (2007). "Sustained increase in flow-mediated dilation after daily intake of high-flavanol cocoa drink over 1 week." J Cardiovasc Pharmacol 49(2): 74-80. PMID: 17312446

Kagemann, G., H. Sies and O. Schnorr (2007). "Limited availability of L-arginine increases DNA-binding activity of NF-kappaB and contributes to regulation of iNOS expression." J Mol Med (Berl) 85(7): 723-732. PMID: 17340133

Neukam, K., W. Stahl, H. Tronnier, H. Sies and U. Heinrich (2007). "Consumption of flavanol-rich cocoa acutely increases microcirculation in human skin." Eur J Nutr 46(1): 53-56. PMID: 17164979

Peterson, L. A., T. Wagener, H. Sies and W. Stahl (2007). "Decomposition of S-nitrosocysteine via S- to N-transnitrosation." Chem Res Toxicol 20(5): 721-723. PMID: 17439249

Polidori, M. C., D. Pratico, B. Parente, E. Mariani, R. Cecchetti, Y. Yao, H. Sies, P. Cao, P. Mecocci and W. Stahl (2007). "Elevated lipid peroxidation biomarkers and low antioxidant status in atherosclerotic patients with increased carotid or iliofemoral intima media thickness." J Investig Med 55(4): 163-167. PMID: 17651669

Sies, H. (2007). "Biological redox systems and oxidative stress." Cell Mol Life Sci 64(17): 2181-2188. PMID: 17565441

Sies, H. (2007). "Total antioxidant capacity: appraisal of a concept." J Nutr 137(6): 1493-1495. PMID: 17513413

Sies, H. (2007). "How I became a biochemist." IUBMB Life 59(7): 469-473. PMID: 17654124

Stahl, W. and H. Sies (2007). "Carotenoids and flavonoids contribute to nutritional protection against skin damage from sunlight." Mol Biotechnol 37(1): 26-30. PMID: 17914160

Steffen, Y., T. Schewe and H. Sies (2007). "(-)-Epicatechin elevates nitric oxide in endothelial cells via inhibition of NADPH oxidase." Biochem Biophys Res Commun 359(3): 828-833. PMID: 17560937

Steffen, Y., T. Jung, L. O. Klotz, T. Schewe, T. Grune and H. Sies (2007). "Protein modification elicited by oxidized low-density lipoprotein (LDL) in endothelial cells: protection by (-)-epicatechin." Free Radic Biol Med 42(7): 955-970. PMID: 17349924

Steinbrenner, H., L. Alili, D. Stuhlmann, H. Sies and P. Brenneisen (2007). "Post-translational processing of selenoprotein P: implications of glycosylation for its utilisation by target cells." Biol Chem 388(10): 1043-1051. PMID: 17937618

Waterman, M. R., P. Fitzpatrick, T. Scarpa and H. Sies (2007). "Highlight issue: enzymology of drug metabolism and toxicology." Arch Biochem Biophys 464(2): 153-154. PMID: 17693151

Beier, J. I., C. von Montfort, H. Sies and L. O. Klotz (2006). "Activation of ErbB2 by 2-methyl-1,4-naphthoquinone (menadione) in human keratinocytes: role of EGFR and protein tyrosine phosphatases." FEBS Lett 580(7): 1859-1864. PMID: 16516204

Cat, B., D. Stuhlmann, H. Steinbrenner, L. Alili, O. Holtkotter, H. Sies and P. Brenneisen (2006). "Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species." J Cell Sci 119(Pt 13): 2727-2738. PMID: 16757516

Engers, R., E. Springer, V. Kehren, T. Simic, D. A. Young, J. Beier, L. O. Klotz, I. M. Clark, H. Sies and H. E. Gabbert (2006). "Rac upregulates tissue inhibitor of metalloproteinase-1 expression by redox-dependent activation of extracellular signal-regulated kinase signaling." FEBS J 273(20): 4754-4769. PMID: 16984397

Heinrich, U., K. Neukam, H. Tronnier, H. Sies and W. Stahl (2006). "Long-term ingestion of high flavanol cocoa provides photoprotection against UV-induced erythema and improves skin condition in women." J Nutr 136(6): 1565-1569. PMID: 16702322

Heiss, C., H. Schroeter, J. Balzer, P. Kleinbongard, S. Matern, H. Sies and M. Kelm (2006). "Endothelial function, nitric oxide, and cocoa flavanols." J Cardiovasc Pharmacol 47 Suppl 2: S128-135; discussion S172-126. PMID: 16794450

Kuhn, M., R. Wolber, L. Kolbe, O. Schnorr and H. Sies (2006). "Solar-simulated radiation induces secretion of IL-6 and production of isoprostanes in human skin in vivo." Arch Dermatol Res 297(10): 477-479. PMID: 16491351

Nesaretnam, K. and H. Sies (2006). "6th COSTAM/SFRR (ASEAN/Malaysia) International Workshop on Micronutrients, Oxidative Stress, and the Environment." Antioxid Redox Signal 8(11-12): 2175-2177. PMID: 17034360

Schroeter, H., C. Heiss, J. Balzer, P. Kleinbongard, C. L. Keen, N. K. Hollenberg, H. Sies, C. Kwik-Uribe, H. H. Schmitz and M. Kelm (2006). "(-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans." Proc Natl Acad Sci U S A 103(4): 1024-1029. PMID: 16418281

Stahl, W., U. Heinrich, O. Aust, H. Tronnier and H. Sies (2006). "Lycopene-rich products and dietary photoprotection." Photochem Photobiol Sci 5(2): 238-242. PMID: 16465309

Steffen, Y., I. Wiswedel, D. Peter, T. Schewe and H. Sies (2006). "Cytotoxicity of myeloperoxidase/nitrite-oxidized low-density lipoprotein toward endothelial cells is due to a high 7beta-hydroxycholesterol to 7-ketocholesterol ratio." Free Radic Biol Med 41(7): 1139-1150. PMID: 16962939

Steffen, Y., T. Schewe and H. Sies (2006). "Myeloperoxidase-mediated LDL oxidation and endothelial cell toxicity of oxidized LDL: attenuation by (-)-epicatechin." Free Radic Res 40(10): 1076-1085. PMID: 17015252

Steinbrenner, H., E. Bilgic, L. Alili, H. Sies and P. Brenneisen (2006). "Selenoprotein P protects endothelial cells from oxidative damage by stimulation of glutathione peroxidase expression and activity." Free Radic Res 40(9): 936-943. PMID: 17015273

Steinbrenner, H., L. Alili, E. Bilgic, H. Sies and P. Brenneisen (2006). "Involvement of selenoprotein P in protection of human astrocytes from oxidative damage." Free Radic Biol Med 40(9): 1513-1523. PMID: 16632112

Suschek, C. V., T. Schewe, H. Sies and K. D. Kroncke (2006). "Nitrite, a naturally occurring precursor of nitric oxide that acts like a 'prodrug'." Biol Chem 387(5): 499-506. PMID: 16740120

von Montfort, C., V. S. Sharov, S. Metzger, C. Schoneich, H. Sies and L. O. Klotz (2006). "Singlet oxygen inactivates protein tyrosine phosphatase-1B by oxidation of the active site cysteine." Biol Chem 387(10-11): 1399-1404. PMID: 17081112

von Montfort, C., N. S. Fernau, J. I. Beier, H. Sies and L. O. Klotz (2006). "Extracellular generation of hydrogen peroxide is responsible for activation of EGF receptor by ultraviolet A radiation." Free Radic Biol Med 41(9): 1478-1487. PMID: 17023275

Walter, P. L., A. Kampkotter, A. Eckers, A. Barthel, D. Schmoll, H. Sies and L. O. Klotz (2006). "Modulation of FoxO signaling in human hepatoma cells by exposure to copper or zinc ions." Arch Biochem Biophys 454(2): 107-113. PMID: 16973122

Abdelmohsen, K., C. von Montfort, D. Stuhlmann, P. A. Gerber, U. K. Decking, H. Sies and L. O. Klotz (2005). "Doxorubicin induces EGF receptor-dependent downregulation of gap junctional intercellular communication in rat liver epithelial cells." Biol Chem 386(3): 217-223. PMID: 15843167

Anlasik, T., H. Sies, H. R. Griffiths, P. Mecocci, W. Stahl and M. C. Polidori (2005). "Dietary habits are major determinants of the plasma antioxidant status in healthy elderly subjects." Br J Nutr 94(5): 639-642. PMID: 16277763

Aust, O., W. Stahl, H. Sies, H. Tronnier and U. Heinrich (2005). "Supplementation with tomato-based products increases lycopene, phytofluene, and phytoene levels in human serum and protects against UV-light-induced erythema." Int J Vitam Nutr Res 75(1): 54-60. PMID: 15830922

Azzi, A., R. Brigelius-Flohe, F. Kelly, J. K. Lodge, N. Ozer, L. Packer and H. Sies (2005). "On the opinion of the European Commission "Scientific Committee on Food" regarding the tolerable upper intake level of vitamin E (2003)." Eur J Nutr 44(1): 60-62. PMID: 15647855

Brenneisen, P., H. Steinbrenner and H. Sies (2005). "Selenium, oxidative stress, and health aspects." Mol Aspects Med 26(4-5): 256-267. PMID: 16105679

Daubrawa, F., H. Sies and W. Stahl (2005). "Astaxanthin diminishes gap junctional intercellular communication in primary human fibroblasts." J Nutr 135(11): 2507-2511. PMID: 16251602

Hathcock, J. N., A. Azzi, J. Blumberg, T. Bray, A. Dickinson, B. Frei, I. Jialal, C. S. Johnston, F. J. Kelly, K. Kraemer, L. Packer, S. Parthasarathy, H. Sies and M. G. Traber (2005). "Vitamins E and C are safe across a broad range of intakes." Am J Clin Nutr 81(4): 736-745. PMID: 15817846

Heiss, C., P. Kleinbongard, A. Dejam, S. Perre, H. Schroeter, H. Sies and M. Kelm (2005). "Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysfunction in smokers." J Am Coll Cardiol 46(7): 1276-1283. PMID: 16198843

Kalai, T., G. Mugesh, G. Roy, H. Sies, Z. Berente and K. Hideg (2005). "Combining benzo[d]isoselenazol-3-ones with sterically hindered alicyclic amines and nitroxides: enhanced activity as glutathione peroxidase mimics." Org Biomol Chem 3(19): 3564-3569. PMID: 16172695

Melchheier, I., C. von Montfort, D. Stuhlmann, H. Sies and L. O. Klotz (2005). "Quinone-induced Cdc25A inhibition causes ERK-dependent connexin phosphorylation." Biochem Biophys Res Commun 327(4): 1016-1023. PMID: 15652497

Polidori, M. C., D. Pratico, T. Ingegni, E. Mariani, L. Spazzafumo, P. Del Sindaco, R. Cecchetti, Y. Yao, S. Ricci, A. Cherubini, W. Stahl, H. Sies, U. Senin, P. Mecocci and A. S. Group (2005). "Effects of vitamin C and aspirin in ischemic stroke-related lipid peroxidation: results of the AVASAS (Aspirin Versus Ascorbic acid plus Aspirin in Stroke) Study." Biofactors 24(1-4): 265-274. PMID: 16403987

Schewe, T. and H. Sies (2005). "Myeloperoxidase-induced lipid peroxidation of LDL in the presence of nitrite. Protection by cocoa flavanols." Biofactors 24(1-4): 49-58. PMID: 16403963

Schnorr, O., M. Schuier, G. Kagemann, R. Wolf, M. Walz, T. Ruzicka, E. Mayatepek, M. Laryea, C. V. Suschek, V. Kolb-Bachofen and H. Sies (2005). "Arginase-1 overexpression induces cationic amino acid transporter-1 in psoriasis." Free Radic Biol Med 38(8): 1073-1079. PMID: 15780765

Schroeder, P., N. Voevodskaya, L. O. Klotz, P. Brenneisen, A. Graslund and H. Sies (2005). "Loss of the tyrosyl radical in mouse ribonucleotide reductase by (-)-epicatechin." Biochem Biophys Res Commun 326(3): 614-617. PMID: 15596143

Schuier, M., H. Sies, B. Illek and H. Fischer (2005). "Cocoa-related flavonoids inhibit CFTR-mediated chloride transport across T84 human colon epithelia." J Nutr 135(10): 2320-2325. PMID: 16177189

Sies, H., W. Stahl and A. Sevanian (2005). "Nutritional, dietary and postprandial oxidative stress." J Nutr 135(5): 969-972. PMID: 15867266

Sies, H., T. Schewe, C. Heiss and M. Kelm (2005). "Cocoa polyphenols and inflammatory mediators." Am J Clin Nutr 81(1 Suppl): 304S-312S. PMID: 15640495

Stahl, W. and H. Sies (2005). "Bioactivity and protective effects of natural carotenoids." Biochim Biophys Acta 1740(2): 101-107. PMID: 15949675

Steffen, Y., T. Schewe and H. Sies (2005). "Epicatechin protects endothelial cells against oxidized LDL and maintains NO synthase." Biochem Biophys Res Commun 331(4): 1277-1283. PMID: 15883014

Steinbrenner, H., M. C. Ramos, D. Stuhlmann, D. Mitic, H. Sies and P. Brenneisen (2005). "Tumor promoter TPA stimulates MMP-9 secretion from human keratinocytes by activation of superoxide-producing NADPH oxidase." Free Radic Res 39(3): 245-253. PMID: 15788229

Abdelmohsen, K., P. Patak, C. Von Montfort, I. Melchheier, H. Sies and L. O. Klotz (2004). "Signaling effects of menadione: from tyrosine phosphatase inactivation to connexin phosphorylation." Methods Enzymol 378: 258-272. PMID: 15038974

Kraemer, T., I. Prakosay, R. A. Date, H. Sies and T. Schewe (2004). "Oxidative modification of low-density lipoprotein: lipid peroxidation by myeloperoxidase in the presence of nitrite." Biol Chem 385(9): 809-818. PMID: 15493876

Mahns, A., R. Wolber, F. Stab, L. O. Klotz and H. Sies (2004). "Contribution of UVB and UVA to UV-dependent stimulation of cyclooxygenase-2 expression in artificial epidermis." Photochem Photobiol Sci 3(3): 257-262. PMID: 14993941

Oh, J. H., A. S. Chung, H. Steinbrenner, H. Sies and P. Brenneisen (2004). "Thioredoxin secreted upon ultraviolet A irradiation modulates activities of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in human dermal fibroblasts." Arch Biochem Biophys 423(1): 218-226. PMID: 14871484

Packer, L., A. Azzi, K. Kraemer, N. Ozer, H. Sies, E. Niki, F. Violi and G. Vatassery (2004). "Future directions in preclinical vitamin E research: panel discussion A." Ann N Y Acad Sci 1031: 305-312. PMID: 15753156

Polidori, M. C., P. Mattioli, S. Aldred, R. Cecchetti, W. Stahl, H. Griffiths, U. Senin, H. Sies and P. Mecocci (2004). "Plasma antioxidant status, immunoglobulin g oxidation and lipid peroxidation in demented patients: relevance to Alzheimer disease and vascular dementia." Dement Geriatr Cogn Disord 18(3-4): 265-270. PMID: 15286458

Ramos, M. C., H. Steinbrenner, D. Stuhlmann, H. Sies and P. Brenneisen (2004). "Induction of MMP-10 and MMP-1 in a squamous cell carcinoma cell line by ultraviolet radiation." Biol Chem 385(1): 75-86. PMID: 14977049

Sies, H. (2004). "Ozone in arteriosclerotic plaques: searching for the "smoking gun"." Angew Chem Int Ed Engl 43(27): 3514-3515. PMID: 15293239

Sies, H. and W. Stahl (2004). "Carotenoids and UV protection." Photochem Photobiol Sci 3(8): 749-752. PMID: 15295630

Sies, H. and W. Stahl (2004). "Nutritional protection against skin damage from sunlight." Annu Rev Nutr 24: 173-200. PMID: 15189118

Stuhlmann, D., H. Steinbrenner, B. Wendlandt, D. Mitic, H. Sies and P. Brenneisen (2004). "Paracrine effect of TGF-beta1 on downregulation of gap junctional intercellular communication between human dermal fibroblasts." Biochem Biophys Res Commun 319(2): 321-326. PMID: 15178409

Traulsen, H., H. Steinbrenner, D. P. Buchczyk, L. O. Klotz and H. Sies (2004). "Selenoprotein P protects low-density lipoprotein against oxidation." Free Radic Res 38(2): 123-128. PMID: 15104205

Wiswedel, I., D. Hirsch, S. Kropf, M. Gruening, E. Pfister, T. Schewe and H. Sies (2004). "Flavanol-rich cocoa drink lowers plasma F(2)-isoprostane concentrations in humans." Free Radic Biol Med 37(3): 411-421. PMID: 15223075

Abdelmohsen, K., P. A. Gerber, C. von Montfort, H. Sies and L. O. Klotz (2003). "Epidermal growth factor receptor is a common mediator of quinone-induced signaling leading to phosphorylation of connexin-43: role of glutathione and tyrosine phosphatases." J Biol Chem 278(40): 38360-38367. PMID: 12874275

Aust, O., N. Ale-Agha, L. Zhang, H. Wollersen, H. Sies and W. Stahl (2003). "Lycopene oxidation product enhances gap junctional communication." Food Chem Toxicol 41(10): 1399-1407. PMID: 12909274

Betancor-Fernandez, A., A. Perez-Galvez, H. Sies and W. Stahl (2003). "Screening pharmaceutical preparations containing extracts of turmeric rhizome, artichoke leaf, devil's claw root and garlic or salmon oil for antioxidant capacity." J Pharm Pharmacol 55(7): 981-986. PMID: 12906755

Buchczyk, D. P., T. Grune, H. Sies and L. O. Klotz (2003). "Modifications of glyceraldehyde-3-phosphate dehydrogenase induced by increasing concentrations of peroxynitrite: early recognition by 20S proteasome." Biol Chem 384(2): 237-241. PMID: 12675516

Giles, G. I., F. H. Fry, K. M. Tasker, A. L. Holme, C. Peers, K. N. Green, L. O. Klotz, H. Sies and C. Jacob (2003). "Evaluation of sulfur, selenium and tellurium catalysts with antioxidant potential." Org Biomol Chem 1(23): 4317-4322. PMID: 14685335

Heinrich, U., C. Gartner, M. Wiebusch, O. Eichler, H. Sies, H. Tronnier and W. Stahl (2003). "Supplementation with beta-carotene or a similar amount of mixed carotenoids protects humans from UV-induced erythema." J Nutr 133(1): 98-101. PMID: 12514275

Heiss, C., A. Dejam, P. Kleinbongard, T. Schewe, H. Sies and M. Kelm (2003). "Vascular effects of cocoa rich in flavan-3-ols." JAMA 290(8): 1030-1031. PMID: 12941674

Jacob, C., G. I. Giles, N. M. Giles and H. Sies (2003). "Sulfur and selenium: the role of oxidation state in protein structure and function." Angew Chem Int Ed Engl 42(39): 4742-4758. PMID: 14562341

Josch, C., L. O. Klotz and H. Sies (2003). "Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine-hydrolysing activity in rat liver." Biol Chem 384(2): 213-218. PMID: 12675513

Klotz, L. O. and H. Sies (2003). "Defenses against peroxynitrite: selenocompounds and flavonoids." Toxicol Lett 140-141: 125-132. PMID: 12676458

Klotz, L. O., K. D. Kroncke, D. P. Buchczyk and H. Sies (2003). "Role of copper, zinc, selenium and tellurium in the cellular defense against oxidative and nitrosative stress." J Nutr 133(5 Suppl 1): 1448S-1451S. PMID: 12730440

Klotz, L. O., K. D. Kroncke and H. Sies (2003). "Singlet oxygen-induced signaling effects in mammalian cells." Photochem Photobiol Sci 2(2): 88-94. PMID: 12664966

Kostyuk, V. A., T. Kraemer, H. Sies and T. Schewe (2003). "Myeloperoxidase/nitrite-mediated lipid peroxidation of low-density lipoprotein as modulated by flavonoids." FEBS Lett 537(1-3): 146-150. PMID: 12606047

Mahns, A., I. Melchheier, C. V. Suschek, H. Sies and L. O. Klotz (2003). "Irradiation of cells with ultraviolet-A (320-400 nm) in the presence of cell culture medium elicits biological effects due to extracellular generation of hydrogen peroxide." Free Radic Res 37(4): 391-397. PMID: 12747733

Mugesh, G., L. O. Klotz, W. W. du Mont, K. Becker and H. Sies (2003). "Selenenyl iodide: a new substrate for mammalian thioredoxin reductase." Org Biomol Chem 1(16): 2848-2852. PMID: 12968334

Perez-Galvez, A., H. D. Martin, H. Sies and W. Stahl (2003). "Incorporation of carotenoids from paprika oleoresin into human chylomicrons." Br J Nutr 89(6): 787-793. PMID: 12828795

Polidori, M. C., P. Mecocci, W. Stahl and H. Sies (2003). "Cigarette smoking cessation increases plasma levels of several antioxidant micronutrients and improves resistance towards oxidative challenge." Br J Nutr 90(1): 147-150. PMID: 12844386

Sadik, C. D., H. Sies and T. Schewe (2003). "Inhibition of 15-lipoxygenases by flavonoids: structure-activity relations and mode of action." Biochem Pharmacol 65(5): 773-781. PMID: 12628491

Schroeder, P., L. O. Klotz and H. Sies (2003). "Amphiphilic properties of (-)-epicatechin and their significance for protection of cells against peroxynitrite." Biochem Biophys Res Commun 307(1): 69-73. PMID: 12849982

Sies, H. and W. Stahl (2003). "Non-nutritive bioactive constituents of plants: lycopene, lutein and zeaxanthin." Int J Vitam Nutr Res 73(2): 95-100. PMID: 12747216

Stahl, W. and H. Sies (2003). "Antioxidant activity of carotenoids." Mol Aspects Med 24(6): 345-351. PMID: 14585305

Steinbrenner, H., M. C. Ramos, D. Stuhlmann, H. Sies and P. Brenneisen (2003). "UVA-mediated downregulation of MMP-2 and MMP-9 in human epidermal keratinocytes." Biochem Biophys Res Commun 308(3): 486-491. PMID: 12914776

Stuhlmann, D., N. Ale-Agha, R. Reinehr, H. Steinbrenner, M. C. Ramos, H. Sies and P. Brenneisen (2003). "Modulation of homologous gap junctional intercellular communication of human dermal fibroblasts via a paracrine factor(s) generated by squamous tumor cells." Carcinogenesis 24(11): 1737-1748. PMID: 12949050

Suschek, C. V., O. Schnorr, K. Hemmrich, O. Aust, L. O. Klotz, H. Sies and V. Kolb-Bachofen (2003). "Critical role of L-arginine in endothelial cell survival during oxidative stress." Circulation 107(20): 2607-2614. PMID: 12742995

Suschek, C. V., P. Schroeder, O. Aust, H. Sies, C. Mahotka, M. Horstjann, H. Ganser, M. Murtz, P. Hering, O. Schnorr, K. D. Kroncke and V. Kolb-Bachofen (2003). "The presence of nitrite during UVA irradiation protects from apoptosis." FASEB J 17(15): 2342-2344. PMID: 14525939

Ale-Agha, N., W. Stahl and H. Sies (2002). "(-)-Epicatechin effects in rat liver epithelial cells: stimulation of gap junctional communication and counteraction of its loss due to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate." Biochem Pharmacol 63(12): 2145-2149. PMID: 12110373

Arteel, G. E., L. O. Klotz, D. P. Buchczyk and H. Sies (2002). "Selenoprotein P." Methods Enzymol 347: 121-125. PMID: 11898401

Betancor-Fernandez, A., H. Sies, W. Stahl and M. C. Polidori (2002). "In vitro antioxidant activity of 2,5,7,8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman (alpha-CEHC), a vitamin E metabolite." Free Radic Res 36(8): 915-921. PMID: 12420750

Brenneisen, P., H. Sies and K. Scharffetter-Kochanek (2002). "Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events." Ann N Y Acad Sci 973: 31-43. PMID: 12485830

Brenneisen, P., M. Wlaschek, E. Schwamborn, L. A. Schneider, W. Ma, H. Sies and K. Scharffetter-Kochanek (2002). "Activation of protein kinase CK2 is an early step in the ultraviolet B-mediated increase in interstitial collagenase (matrix metalloproteinase-1; MMP-1) and stromelysin-1 (MMP-3) protein levels in human dermal fibroblasts." Biochem J 365(Pt 1): 31-40. PMID: 12071839

Eichler, O., H. Sies and W. Stahl (2002). "Divergent optimum levels of lycopene, beta-carotene and lutein protecting against UVB irradiation in human fibroblastst." Photochem Photobiol 75(5): 503-506. PMID: 12017476

Jorge, S. A., C. F. Menck, H. Sies, M. R. Osborne, D. H. Phillips, A. Sarasin and A. Stary (2002). "Mutagenic fingerprint of ozone in human cells." DNA Repair (Amst) 1(5): 369-378. PMID: 12509241

Klotz, L. O. and H. Sies (2002). "Reversible conversion of nitroxyl anion to nitric oxide." Methods Enzymol 349: 101-106. PMID: 11912899

Klotz, L. O., P. Schroeder and H. Sies (2002). "Peroxynitrite signaling: receptor tyrosine kinases and activation of stress-responsive pathways." Free Radic Biol Med 33(6): 737-743. PMID: 12208362

Klotz, L. O., P. Patak, N. Ale-Agha, D. P. Buchczyk, K. Abdelmohsen, P. A. Gerber, C. von Montfort and H. Sies (2002). "2-Methyl-1,4-naphthoquinone, vitamin K(3), decreases gap-junctional intercellular communication via activation of the epidermal growth factor receptor/extracellular signal-regulated kinase cascade." Cancer Res 62(17): 4922-4928. PMID: 12208742

Kroncke, K. D., L. O. Klotz, C. V. Suschek and H. Sies (2002). "Comparing nitrosative versus oxidative stress toward zinc finger-dependent transcription. Unique role for NO." J Biol Chem 277(15): 13294-13301. PMID: 11796720

McKim, S. E., A. Konno, E. Gabele, T. Uesugi, M. Froh, H. Sies, R. G. Thurman and G. E. Arteel (2002). "Cocoa extract protects against early alcohol-induced liver injury in the rat." Arch Biochem Biophys 406(1): 40-46. PMID: 12234488

Ostrakhovitch, E. A., M. R. Lordnejad, F. Schliess, H. Sies and L. O. Klotz (2002). "Copper ions strongly activate the phosphoinositide-3-kinase/Akt pathway independent of the generation of reactive oxygen species." Arch Biochem Biophys 397(2): 232-239. PMID: 11795876

Polidori, M. C., A. Cherubini, W. Stahl, U. Senin, H. Sies and P. Mecocci (2002). "Plasma carotenoid and malondialdehyde levels in ischemic stroke patients: relationship to early outcome." Free Radic Res 36(3): 265-268. PMID: 12071344

Polidori, M. C., K. Savino, G. Alunni, M. Freddio, U. Senin, H. Sies, W. Stahl and P. Mecocci (2002). "Plasma lipophilic antioxidants and malondialdehyde in congestive heart failure patients: relationship to disease severity." Free Radic Biol Med 32(2): 148-152. PMID: 11796203

Radosavac, D., P. Graf, M. C. Polidori, H. Sies and W. Stahl (2002). "Tocopherol metabolites 2, 5, 7, 8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman (alpha-CEHC) and 2, 7, 8-trimethyl-2-(2'-carboxyethyl)-6-hydroxychroman (gamma-CEHC) in human serum after a single dose of natural vitamin E." Eur J Nutr 41(3): 119-124. PMID: 12111049

Schewe, T., H. Kuhn and H. Sies (2002). "Flavonoids of cocoa inhibit recombinant human 5-lipoxygenase." J Nutr 132(7): 1825-1829. PMID: 12097654

Schieke, S., H. Stege, V. Kurten, S. Grether-Beck, H. Sies and J. Krutmann (2002). "Infrared-A radiation-induced matrix metalloproteinase 1 expression is mediated through extracellular signal-regulated kinase 1/2 activation in human dermal fibroblasts." J Invest Dermatol 119(6): 1323-1329. PMID: 12485435

Stahl, W. and H. Sies (2002). "Carotenoids and protection against solar UV radiation." Skin Pharmacol Appl Skin Physiol 15(5): 291-296. PMID: 12239422

Al-Mustafa, A. H., H. Sies and W. Stahl (2001). "Sulfur-to-nitrogen transnitrosation: transfer of nitric oxide from S-nitroso compounds to diethanolamine and the role of intermediate sulfur-to-sulfur transnitrosation." Toxicology 163(2-3): 127-136. PMID: 11516522

Arteel, G. E. and H. Sies (2001). "The biochemistry of selenium and the glutathione system." Environ Toxicol Pharmacol 10(4): 153-158. PMID: 21782571

Aust, O., H. Sies, W. Stahl and M. C. Polidori (2001). "Analysis of lipophilic antioxidants in human serum and tissues: tocopherols and carotenoids." J Chromatogr A 936(1-2): 83-93. PMID: 11761008

Bruch-Gerharz, D., W. Stahl, C. D. Gerharz, M. Megahed, T. Wingerath, H. Sies and T. Ruzicka (2001). "Accumulation of the xanthophyll lutein in skin amyloid deposits of systemic amyloidosis (al type)." J Invest Dermatol 116(1): 196-197. PMID: 11168818

Buchczyk, D. P., L. O. Klotz, K. Lang, C. Fritsch and H. Sies (2001). "High efficiency of 5-aminolevulinate-photodynamic treatment using UVA irradiation." Carcinogenesis 22(6): 879-883. PMID: 11375893

Fu, Y., H. Sies and X. G. Lei (2001). "Opposite roles of selenium-dependent glutathione peroxidase-1 in superoxide generator diquat- and peroxynitrite-induced apoptosis and signaling." J Biol Chem 276(46): 43004-43009. PMID: 11562367

Grune, T., L. O. Klotz, J. Gieche, M. Rudeck and H. Sies (2001). "Protein oxidation and proteolysis by the nonradical oxidants singlet oxygen or peroxynitrite." Free Radic Biol Med 30(11): 1243-1253. PMID: 11368922

Junghans, A., H. Sies and W. Stahl (2001). "Macular pigments lutein and zeaxanthin as blue light filters studied in liposomes." Arch Biochem Biophys 391(2): 160-164. PMID: 11437346

Klotz, L. O., N. J. Holbrook and H. Sies (2001). "UVA and singlet oxygen as inducers of cutaneous signaling events." Curr Probl Dermatol 29: 95-113. PMID: 11225205

Kono, H., G. E. Arteel, I. Rusyn, H. Sies and R. G. Thurman (2001). "Ebselen prevents early alcohol-induced liver injury in rats." Free Radic Biol Med 30(4): 403-411. PMID: 11182296

Lang, K., K. Bolsen, W. Stahl, T. Ruzicka, H. Sies, P. Lehmann and C. Fritsch (2001). "The 5-aminolevulinic acid-induced porphyrin biosynthesis in benign and malignant cells of the skin." J Photochem Photobiol B 65(1): 29-34. PMID: 11748002

Mugesh, G., W. W. du Mont and H. Sies (2001). "Chemistry of biologically important synthetic organoselenium compounds." Chem Rev 101(7): 2125-2179. PMID: 11710243

Onat, D., W. Stahl and H. Sies (2001). "Stimulation of gap junctional intercellular communication by thalidomide and thalidomide analogs in human fetal skin fibroblasts (HFFF2) and in rat liver epithelial cells (WB-F344)." Biochem Pharmacol 62(8): 1081-1086. PMID: 11597576

Polidori, M. C., W. Stahl, O. Eichler, I. Niestroj and H. Sies (2001). "Profiles of antioxidants in human plasma." Free Radic Biol Med 30(5): 456-462. PMID: 11182517

Schewe, T., C. Sadik, L. O. Klotz, T. Yoshimoto, H. Kuhn and H. Sies (2001). "Polyphenols of cocoa: inhibition of mammalian 15-lipoxygenase." Biol Chem 382(12): 1687-1696. PMID: 11843182

Schroeder, P., L. O. Klotz, D. P. Buchczyk, C. D. Sadik, T. Schewe and H. Sies (2001). "Epicatechin selectively prevents nitration but not oxidation reactions of peroxynitrite." Biochem Biophys Res Commun 285(3): 782-787. PMID: 11453660

Schroeder, P., H. Zhang, L. O. Klotz, B. Kalyanaraman and H. Sies (2001). "(-)-Epicatechin inhibits nitration and dimerization of tyrosine in hydrophilic as well as hydrophobic environments." Biochem Biophys Res Commun 289(5): 1334-1338. PMID: 11741342

Stahl, W., U. Heinrich, S. Wiseman, O. Eichler, H. Sies and H. Tronnier (2001). "Dietary tomato paste protects against ultraviolet light-induced erythema in humans." J Nutr 131(5): 1449-1451. PMID: 11340098

Stahl, W. and H. Sies (2001). "Effects of carotenoids and retinoids on gap junctional communication." Biofactors 15(2-4): 95-98. PMID: 12016334

Suschek, C. V., K. Briviba, D. Bruch-Gerharz, H. Sies, K. D. Kroncke and V. Kolb-Bachofen (2001). "Even after UVA-exposure will nitric oxide protect cells from reactive oxygen intermediate-mediated apoptosis and necrosis." Cell Death Differ 8(5): 515-527. PMID: 11423912

Wagner, G., K. Stettmaier, W. Bors, H. Sies, E. M. Wagner, A. Reuter and H. Weiher (2001). "Enhanced gamma-glutamyl transpeptidase expression and superoxide production in Mpv17-/- glomerulosclerosis mice." Biol Chem 382(7): 1019-1025. PMID: 11530932

Arteel, G. E., P. Schroeder and H. Sies (2000). "Reactions of peroxynitrite with cocoa procyanidin oligomers." J Nutr 130(8S Suppl): 2100S-2104S. PMID: 10917929

Arteel, G. E., S. Franken, J. Kappler and H. Sies (2000). "Binding of selenoprotein P to heparin: characterization with surface plasmon resonance." Biol Chem 381(3): 265-268. PMID: 10782998

Assmann, A., M. Bonifacic, K. Briviba, H. Sies and K. D. Asmus (2000). "One-electron reduction of selenomethionine oxide." Free Radic Res 32(4): 371-376. PMID: 10741858

Briviba, K. and H. Sies (2000). "Biological singlet oxygen quenchers assessed by monomol light emission." Methods Enzymol 319: 222-226. PMID: 10907514

Buchczyk, D. P., K. Briviba, F. U. Hartl and H. Sies (2000). "Responses to peroxynitrite in yeast: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a sensitive intracellular target for nitration and enhancement of chaperone expression and ubiquitination." Biol Chem 381(2): 121-126. PMID: 10746743

Cadenas, E. and H. Sies (2000). "Formation of electronically excited states during the oxidation of arachidonic acid by prostaglandin endoperoxide synthase." Methods Enzymol 319: 67-77. PMID: 10907500

Gladilin, S., H. J. Bidmon, A. Divanach, G. E. Arteel, O. W. Witte, K. Zilles and H. Sies (2000). "Ebselen lowers plasma interleukin-6 levels and glial heme oxygenase-1 expression after focal photothrombotic brain ischemia." Arch Biochem Biophys 380(2): 237-242. PMID: 10933877

Grether-Beck, S., G. Bonizzi, H. Schmitt-Brenden, I. Felsner, A. Timmer, H. Sies, J. P. Johnson, J. Piette and J. Krutmann (2000). "Non-enzymatic triggering of the ceramide signalling cascade by solar UVA radiation." EMBO J 19(21): 5793-5800. PMID: 11060030

Jacob, C., G. E. Arteel, T. Kanda, L. Engman and H. Sies (2000). "Water-soluble organotellurium compounds: catalytic protection against peroxynitrite and release of zinc from metallothionein." Chem Res Toxicol 13(1): 3-9. PMID: 10649960

Junghans, A., H. Sies and W. Stahl (2000). "Carotenoid-containing unilamellar liposomes loaded with glutathione: a model to study hydrophobic-hydrophilic antioxidant interaction." Free Radic Res 33(6): 801-808. PMID: 11237102

Klotz, L. O., K. Briviba and H. Sies (2000). "Mitogen-activated protein kinase activation by singlet oxygen and ultraviolet A." Methods Enzymol 319: 130-143. PMID: 10907506

Klotz, L. O., S. M. Schieke, H. Sies and N. J. Holbrook (2000). "Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts." Biochem J 352 Pt 1: 219-225. PMID: 11062076

Martinez, G. R., P. Di Mascio, M. G. Bonini, O. Augusto, K. Briviba, H. Sies, P. Maurer, U. Rothlisberger, S. Herold and W. H. Koppenol (2000). "Peroxynitrite does not decompose to singlet oxygen ((1)Delta (g)O(2)) andnitroxyl (NO(-))." Proc Natl Acad Sci U S A 97(19): 10307-10312. PMID: 10973492

Mecocci, P., M. C. Polidori, L. Troiano, A. Cherubini, R. Cecchetti, G. Pini, M. Straatman, D. Monti, W. Stahl, H. Sies, C. Franceschi and U. Senin (2000). "Plasma antioxidants and longevity: a study on healthy centenarians." Free Radic Biol Med 28(8): 1243-1248. PMID: 10889454

Panasenko, O. M., V. S. Sharov, K. Briviba and H. Sies (2000). "Interaction of peroxynitrite with carotenoids in human low density lipoproteins." Arch Biochem Biophys 373(1): 302-305. PMID: 10620353

Parnham, M. and H. Sies (2000). "Ebselen: prospective therapy for cerebral ischaemia." Expert Opin Investig Drugs 9(3): 607-619. PMID: 11060699

Pierlot, C., J. M. Aubry, K. Briviba, H. Sies and P. Di Mascio (2000). "Naphthalene endoperoxides as generators of singlet oxygen in biological media." Methods Enzymol 319: 3-20. PMID: 10907494

Polidori, M. C., P. Mecocci, W. Stahl, B. Parente, R. Cecchetti, A. Cherubini, P. Cao, H. Sies and U. Senin (2000). "Plasma levels of lipophilic antioxidants in very old patients with type 2 diabetes." Diabetes Metab Res Rev 16(1): 15-19. PMID: 10707034

Possel, H., H. Noack, J. Putzke, G. Wolf and H. Sies (2000). "Selective upregulation of inducible nitric oxide synthase (iNOS) by lipopolysaccharide (LPS) and cytokines in microglia: in vitro and in vivo studies." Glia 32(1): 51-59. PMID: 10975910

Sies, H. and G. E. Arteel (2000). "Interaction of peroxynitrite with selenoproteins and glutathione peroxidase mimics." Free Radic Biol Med 28(10): 1451-1455. PMID: 10927168

Stahl, W., J. von Laar, H. D. Martin, T. Emmerich and H. Sies (2000). "Stimulation of gap junctional communication: comparison of acyclo-retinoic acid and lycopene." Arch Biochem Biophys 373(1): 271-274. PMID: 10620348

Stahl, W., U. Heinrich, H. Jungmann, H. Tronnier and H. Sies (2000). "Carotenoids in human skin: noninvasive measurement and identification of dermal carotenoids and carotenol esters." Methods Enzymol 319: 494-502. PMID: 10907537

Stahl, W., U. Heinrich, H. Jungmann, H. Sies and H. Tronnier (2000). "Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans." Am J Clin Nutr 71(3): 795-798. PMID: 10702175

Stock, A. and H. Sies (2000). "Thyroid hormone receptors bind to an element in the connexin43 promoter." Biol Chem 381(9-10): 973-979. PMID: 11076030

Arteel, G. E., K. Briviba and H. Sies (1999). "Function of thioredoxin reductase as a peroxynitrite reductase using selenocystine or ebselen." Chem Res Toxicol 12(3): 264-269. PMID: 10077489

Arteel, G. E. and H. Sies (1999). "Protection against peroxynitrite by cocoa polyphenol oligomers." FEBS Lett 462(1-2): 167-170. PMID: 10580113

Arteel, G. E., K. Briviba and H. Sies (1999). "Protection against peroxynitrite." FEBS Lett 445(2-3): 226-230. PMID: 10094462

Ballmaier, D., K. Briviba, H. Sies and B. Epe (1999). "Use of repair endonucleases to assess DNA damage by peroxynitrite." Methods Enzymol 301: 311-318. PMID: 9919580

Berneburg, M., S. Grether-Beck, V. Kurten, T. Ruzicka, K. Briviba, H. Sies and J. Krutmann (1999). "Singlet oxygen mediates the UVA-induced generation of the photoaging-associated mitochondrial common deletion." J Biol Chem 274(22): 15345-15349. PMID: 10336420

Briviba, K., L. O. Klotz and H. Sies (1999). "Defenses against peroxynitrite." Methods Enzymol 301: 301-311. PMID: 9919579

Clairmont, A., H. Sies, S. Ramachandran, J. T. Lear, A. G. Smith, B. Bowers, P. W. Jones, A. A. Fryer and R. C. Strange (1999). "Association of NAD(P)H:quinone oxidoreductase (NQO1) null with numbers of basal cell carcinomas: use of a multivariate model to rank the relative importance of this polymorphism and those at other relevant loci." Carcinogenesis 20(7): 1235-1240. PMID: 10383895

Fritsch, C., P. Lehmann, W. Stahl, K. W. Schulte, E. Blohm, K. Lang, H. Sies and T. Ruzicka (1999). "Optimum porphyrin accumulation in epithelial skin tumours and psoriatic lesions after topical application of delta-aminolaevulinic acid." Br J Cancer 79(9-10): 1603-1608. PMID: 10188913

Ji, Y., T. P. Akerboom, H. Sies and J. A. Thomas (1999). "S-nitrosylation and S-glutathiolation of protein sulfhydryls by S-nitroso glutathione." Arch Biochem Biophys 362(1): 67-78. PMID: 9917330

Ji, Y., T. P. Akerboom, H. Sies and J. A. Thomas (1999). "Gel electrofocusing method for studying protein S-nitrosylation." Methods Enzymol 301: 145-151. PMID: 9919562

Klotz, L. O., C. Pellieux, K. Briviba, C. Pierlot, J. M. Aubry and H. Sies (1999). "Mitogen-activated protein kinase (p38-, JNK-, ERK-) activation pattern induced by extracellular and intracellular singlet oxygen and UVA." Eur J Biochem 260(3): 917-922. PMID: 10103024

Polidori, M. C., P. Mecocci, A. Reimann, A. Cherubini, R. Cecchetti, K. Briviba, W. Stahl, H. Sies and U. Senin (1999). "Plasma lipid peroxidation and vitamin C status in healthy centenarians." J Am Geriatr Soc 47(8): 1038-1039. PMID: 10443874

Schieke, S. M., K. Briviba, L. O. Klotz and H. Sies (1999). "Activation pattern of mitogen-activated protein kinases elicited by peroxynitrite: attenuation by selenite supplementation." FEBS Lett 448(2-3): 301-303. PMID: 10218497

Sharov, V. S., K. Briviba and H. Sies (1999). "Peroxynitrite diminishes gap junctional communication: protection by selenite supplementation." IUBMB Life 48(4): 379-384. PMID: 10632565

Sies, H. (1999). "Glutathione and its role in cellular functions." Free Radic Biol Med 27(9-10): 916-921. PMID: 10569624

Sies, H. (1999). "Paper of the year 1998: award to Karin Post and Martin Pitschke." Biol Chem 380(7-8): 735. PMID: 10494822

Stahl, W., P. Graf, R. Brigelius-Flohe, W. Wechter and H. Sies (1999). "Quantification of the alpha- and gamma-tocopherol metabolites 2,5,7, 8-tetramethyl-2-(2'-carboxyethyl)-6-hydroxychroman and 2,7, 8-trimethyl-2-(2'-carboxyethyl)-6-hydroxychroman in human serum." Anal Biochem 275(2): 254-259. PMID: 10552913

Teicher, V. B., N. Kucharski, H. D. Martin, P. van der Saag, H. Sies and W. Stahl (1999). "Biological activities of Apo-canthaxanthinoic acids related to gap junctional communication." Arch Biochem Biophys 365(1): 150-155. PMID: 10222049

Thiele, J. J., S. N. Hsieh, K. Briviba and H. Sies (1999). "Protein oxidation in human stratum corneum: susceptibility of keratins to oxidation in vitro and presence of a keratin oxidation gradient in vivo." J Invest Dermatol 113(3): 335-339. PMID: 10469330

Arteel, G. E., V. Mostert, H. Oubrahim, K. Briviba, J. Abel and H. Sies (1998). "Protection by selenoprotein P in human plasma against peroxynitrite-mediated oxidation and nitration." Biol Chem 379(8-9): 1201-1205. PMID: 9792455

Assmann, A., K. Briviba and H. Sies (1998). "Reduction of methionine selenoxide to selenomethionine by glutathione." Arch Biochem Biophys 349(1): 201-203. PMID: 9439599

Brenneisen, P., J. Wenk, L. O. Klotz, M. Wlaschek, K. Briviba, T. Krieg, H. Sies and K. Scharffetter-Kochanek (1998). "Central role of Ferrous/Ferric iron in the ultraviolet B irradiation-mediated signaling pathway leading to increased interstitial collagenase (matrix-degrading metalloprotease (MMP)-1) and stromelysin-1 (MMP-3) mRNA levels in cultured human dermal fibroblasts." J Biol Chem 273(9): 5279-5287. PMID: 9478985

Briviba, K., R. Kissner, W. H. Koppenol and H. Sies (1998). "Kinetic study of the reaction of glutathione peroxidase with peroxynitrite." Chem Res Toxicol 11(12): 1398-1401. PMID: 9860480

Briviba, K., R. Tamler, L. O. Klotz, L. Engman, I. A. Cotgreave and H. Sies (1998). "Protection by organotellurium compounds against peroxynitrite-mediated oxidation and nitration reactions." Biochem Pharmacol 55(6): 817-823. PMID: 9586954

Cadenas, E. and H. Sies (1998). "The lag phase." Free Radic Res 28(6): 601-609. PMID: 9736312

Fritsch, C., B. Homey, W. Stahl, P. Lehmann, T. Ruzicka and H. Sies (1998). "Preferential relative porphyrin enrichment in solar keratoses upon topical application of delta-aminolevulinic acid methylester." Photochem Photobiol 68(2): 218-221. PMID: 9723214

Herrmann, G., P. Brenneisen, M. Wlaschek, J. Wenk, K. Faisst, G. Quel, C. Hommel, G. Goerz, T. Ruzicka, T. Krieg, H. Sies and K. Scharffetter-Kochanek (1998). "Psoralen photoactivation promotes morphological and functional changes in fibroblasts in vitro reminiscent of cellular senescence." J Cell Sci 111 ( Pt 6): 759-767. PMID: 9472004

Josch, C., H. Sies and T. P. Akerboom (1998). "Hepatic mercapturic acid formation: involvement of cytosolic cysteinylglycine S-conjugate dipeptidase activity." Biochem Pharmacol 56(6): 763-771. PMID: 9751082

Klotz, L. O., C. Fritsch, K. Briviba, N. Tsacmacidis, F. Schliess and H. Sies (1998). "Activation of JNK and p38 but not ERK MAP kinases in human skin cells by 5-aminolevulinate-photodynamic therapy." Cancer Res 58(19): 4297-4300. PMID: 9766656

Lorper, M., A. Clairmont, C. Carlberg and H. Sies (1998). "Identification of two activating elements in the proximal promoter region of the human glutathione transferase-A1 and -A2 genes." Arch Biochem Biophys 359(1): 122-127. PMID: 9799569

Schulz, W. A., A. Krummeck, I. Rosinger, B. J. Schmitz-Drager and H. Sies (1998). "Predisposition towards urolithiasis associated with the NQO1 null-allele." Pharmacogenetics 8(5): 453-454. PMID: 9825838

Sies, H., L. O. Klotz, V. S. Sharov, A. Assmann and K. Briviba (1998). "Protection against peroxynitrite by selenoproteins." Z Naturforsch C 53(3-4): 228-232. PMID: 9618937

Sies, H. and W. Stahl (1998). "Lycopene: antioxidant and biological effects and its bioavailability in the human." Proc Soc Exp Biol Med 218(2): 121-124. PMID: 9605209

Sies, H., A. L. Dafre, Y. Ji and T. P. Akerboom (1998). "Protein S-thiolation and redox regulation of membrane-bound glutathione transferase." Chem Biol Interact 111-112: 177-185. PMID: 9679553

Sies, H. (1998). "Paper of the Year 1997: Award to Everson Nogoceke." Biol Chem 379(8-9): 939. PMID: 9792426

Sompayrac, L., S. Jane, M. Lorper and H. Sies (1998). "A 47-amino-acid fragment of SV40 T antigen represses transcription from human GSTalpha promoters." Virology 249(2): 275-285. PMID: 9791019

Stahl, W., U. Heinrich, H. Jungmann, J. von Laar, M. Schietzel, H. Sies and H. Tronnier (1998). "Increased dermal carotenoid levels assessed by noninvasive reflection spectrophotometry correlate with serum levels in women ingesting Betatene." J Nutr 128(5): 903-907. PMID: 9567001

Stahl, W. and H. Sies (1998). "The role of carotenoids and retinoids in gap junctional communication." Int J Vitam Nutr Res 68(6): 354-359. PMID: 9857261

Stahl, W., A. Junghans, B. de Boer, E. S. Driomina, K. Briviba and H. Sies (1998). "Carotenoid mixtures protect multilamellar liposomes against oxidative damage: synergistic effects of lycopene and lutein." FEBS Lett 427(2): 305-308. PMID: 9607334

Stock, A., H. Sies and W. Stahl (1998). "Enhancement of gap junctional communication and connexin43 expression by thyroid hormones." Biochem Pharmacol 55(4): 475-479. PMID: 9514082

Wingerath, T., H. Sies and W. Stahl (1998). "Xanthophyll esters in human skin." Arch Biochem Biophys 355(2): 271-274. PMID: 9675037

Akerboom, T. P., Y. Ji, G. Wagner and H. Sies (1997). "Subunit specificity and organ distribution of glutathione transferase-catalysed S-nitrosoglutathione formation from alkyl nitrites in the rat." Biochem Pharmacol 53(1): 117-120. PMID: 8960071

Biesalski, H. K., H. Bohles, H. Esterbauer, P. Furst, F. Gey, G. Hundsdorfer, H. Kasper, H. Sies and J. Weisburger (1997). "Antioxidant vitamins in prevention." Clin Nutr 16(3): 151-155. PMID: 16844591

Briviba, K., L. O. Klotz and H. Sies (1997). "Toxic and signaling effects of photochemically or chemically generated singlet oxygen in biological systems." Biol Chem 378(11): 1259-1265. PMID: 9426185

Clairmont, A. and H. Sies (1997). "Evidence for a posttranscriptional effect of retinoic acid on connexin43 gene expression via the 3'-untranslated region." FEBS Lett 419(2-3): 268-270. PMID: 9428648

Di Mascio, P., K. Briviba, S. T. Sasaki, L. H. Catalani, M. H. Medeiros, E. J. Bechara and H. Sies (1997). "The reaction of peroxynitrite with tert-butyl hydroperoxide produces singlet molecular oxygen." Biol Chem 378(9): 1071-1074. PMID: 9348119

Fritsch, C., C. Abels, A. E. Goetz, W. Stahl, K. Bolsen, T. Ruzicka, G. Goerz and H. Sies (1997). "Porphyrins preferentially accumulate in a melanoma following intravenous injection of 5-aminolevulinic acid." Biol Chem 378(1): 51-57. PMID: 9049065

Gartner, C., W. Stahl and H. Sies (1997). "Lycopene is more bioavailable from tomato paste than from fresh tomatoes." Am J Clin Nutr 66(1): 116-122. PMID: 9209178

Klotz, L. O., K. Briviba and H. Sies (1997). "Singlet oxygen mediates the activation of JNK by UVA radiation in human skin fibroblasts." FEBS Lett 408(3): 289-291. PMID: 9188778

Morita, A., T. Werfel, H. Stege, C. Ahrens, K. Karmann, M. Grewe, S. Grether-Beck, T. Ruzicka, A. Kapp, L. O. Klotz, H. Sies and J. Krutmann (1997). "Evidence that singlet oxygen-induced human T helper cell apoptosis is the basic mechanism of ultraviolet-A radiation phototherapy." J Exp Med 186(10): 1763-1768. PMID: 9362536

Nicolai, S., H. Sies and W. Stahl (1997). "Stimulation of gap junctional intercellular communication by thalidomide and thalidomide analogs in human skin fibroblasts." Biochem Pharmacol 53(10): 1553-1557. PMID: 9260883

Panasenko, O. M., O. O. Panasenko, K. Briviba and H. Sies (1997). "Hypochlorite destroys carotenoids in low density lipoproteins thus decreasing their resistance to peroxidative modification." Biochemistry (Mosc) 62(10): 1140-1145. PMID: 9461636

Panasenko, O. M., K. Briviba, L. O. Klotz and H. Sies (1997). "Oxidative modification and nitration of human low-density lipoproteins by the reaction of hypochlorous acid with nitrite." Arch Biochem Biophys 343(2): 254-259. PMID: 9224738

Schulz, W. A., A. Krummeck, I. Rosinger, P. Eickelmann, C. Neuhaus, T. Ebert, B. J. Schmitz-Drager and H. Sies (1997). "Increased frequency of a null-allele for NAD(P)H: quinone oxidoreductase in patients with urological malignancies." Pharmacogenetics 7(3): 235-239. PMID: 9241663

Sies, H. (1997). "Oxidative stress: oxidants and antioxidants." Exp Physiol 82(2): 291-295. PMID: 9129943

Sies, H. and W. Stahl (1997). "Carotenoids and intercellular communication via gap junctions." Int J Vitam Nutr Res 67(5): 364-367. PMID: 9350479

Sies, H., V. S. Sharov, L. O. Klotz and K. Briviba (1997). "Glutathione peroxidase protects against peroxynitrite-mediated oxidations. A new function for selenoproteins as peroxynitrite reductase." J Biol Chem 272(44): 27812-27817. PMID: 9346926

Sies, H. and H. Masumoto (1997). "Ebselen as a glutathione peroxidase mimic and as a scavenger of peroxynitrite." Adv Pharmacol 38: 229-246. PMID: 8895811

Stahl, W. and H. Sies (1997). "Antioxidant defense: vitamins E and C and carotenoids." Diabetes 46 Suppl 2: S14-18. PMID: 9285493

Stahl, W., S. Nicolai, K. Briviba, M. Hanusch, G. Broszeit, M. Peters, H. D. Martin and H. Sies (1997). "Biological activities of natural and synthetic carotenoids: induction of gap junctional communication and singlet oxygen quenching." Carcinogenesis 18(1): 89-92. PMID: 9054593

von Herbay, A., W. Stahl, C. Niederau and H. Sies (1997). "Vitamin E improves the aminotransferase status of patients suffering from viral hepatitis C: a randomized, double-blind, placebo-controlled study." Free Radic Res 27(6): 599-605. PMID: 9455695

Wlaschek, M., J. Wenk, P. Brenneisen, K. Briviba, A. Schwarz, H. Sies and K. Scharffetter-Kochanek (1997). "Singlet oxygen is an early intermediate in cytokine-dependent ultraviolet-A induction of interstitial collagenase in human dermal fibroblasts in vitro." FEBS Lett 413(2): 239-242. PMID: 9280289

Brenneisen, P., J. Oh, M. Wlaschek, J. Wenk, K. Briviba, C. Hommel, G. Herrmann, H. Sies and K. Scharffetter-Kochanek (1996). "Ultraviolet B wavelength dependence for the regulation of two major matrix-metalloproteinases and their inhibitor TIMP-1 in human dermal fibroblasts." Photochem Photobiol 64(4): 649-657. PMID: 8863471

Brenneisen, P., J. Oh, M. Wlaschek, J. Wenk, K. Briviba, C. Hommel, G. Herrmann, H. Sies and K. Scharffetter-Kochanek (1996). "Ultraviolet B wavelength dependence for the regulation of two major matrix-metalloproteinases and their inhibitor TIMP-1 in human dermal fibroblasts." Photochem Photobiol 64(5): 877-885. PMID: 8931389

Briviba, K., C. R. Saha-Moller, W. Adam and H. Sies (1996). "Formation of singlet oxygen in the thermal decomposition of 3-hydroxymethyl-3,4,4-trimethyl-1,2-dioxetane, a chemical source of triplet-excited ketones." Biochem Mol Biol Int 38(4): 647-651. PMID: 8728092

Briviba, K., I. Roussyn, V. S. Sharov and H. Sies (1996). "Attenuation of oxidation and nitration reactions of peroxynitrite by selenomethionine, selenocystine and ebselen." Biochem J 319 ( Pt 1): 13-15. PMID: 8870642

Clairmont, A., D. Tessman, A. Stock, S. Nicolai, W. Stahl and H. Sies (1996). "Induction of gap junctional intercellular communication by vitamin D in human skin fibroblasts is dependent on the nuclear Induction of gap junctional intercellular communication by vitamin D in human skin fibroblasts is dependent on the nuclear vitamin D receptor." Carcinogenesis 17(6): 1389-1391. PMID: 8681462

Clairmont, A., D. Tessmann and H. Sies (1996). "Analysis of connexin43 gene expression induced by retinoic acid in F9 teratocarcinoma cells." FEBS Lett 397(1): 22-24. PMID: 8941706

Dafre, A. L., H. Sies and T. Akerboom (1996). "Protein S-thiolation and regulation of microsomal glutathione transferase activity by the glutathione redox couple." Arch Biochem Biophys 332(2): 288-294. PMID: 8806737

Di Mascio, P., K. Briviba, E. J. Bechara, M. H. Medeiros and H. Sies (1996). "Reaction of peroxynitrite and hydrogen peroxide to produce singlet molecular oxygen (1deltag)." Methods Enzymol 269: 395-400. PMID: 8791668

Epe, B., D. Ballmaier, I. Roussyn, K. Briviba and H. Sies (1996). "DNA damage by peroxynitrite characterized with DNA repair enzymes." Nucleic Acids Res 24(21): 4105-4110. PMID: 8932358

Gartner, C., W. Stahl and H. Sies (1996). "Preferential increase in chylomicron levels of the xanthophylls lutein and zeaxanthin compared to beta-carotene in the human." Int J Vitam Nutr Res 66(2): 119-125. PMID: 8843986

Grether-Beck, S., S. Olaizola-Horn, H. Schmitt, M. Grewe, A. Jahnke, J. P. Johnson, K. Briviba, H. Sies and J. Krutmann (1996). "Activation of transcription factor AP-2 mediates UVA radiation- and singlet oxygen-induced expression of the human intercellular adhesion molecule 1 gene." Proc Natl Acad Sci U S A 93(25): 14586-14591. PMID: 8962096

Ji, Y., T. P. Akerboom and H. Sies (1996). "Microsomal formation of S-nitrosoglutathione from organic nitrites: possible role of membrane-bound glutathione transferase." Biochem J 313 ( Pt 2): 377-380. PMID: 8573068

Kaufmann, R., T. Wingerath, D. Kirsch, W. Stahl and H. Sies (1996). "Analysis of carotenoids and carotenol fatty acid esters by matrix-assisted laser desorption ionization (MALDI) and MALDI-post-source-decay mass spectrometry." Anal Biochem 238(2): 117-128. PMID: 8660600

Lorper, M., W. A. Schulz, F. Morel, U. Warskulat and H. Sies (1996). "Positive and negative regulatory regions in promoters of human glutathione transferase alpha genes." Biol Chem Hoppe Seyler 377(1): 39-46. PMID: 8929812

Masumoto, H., R. Kissner, W. H. Koppenol and H. Sies (1996). "Kinetic study of the reaction of ebselen with peroxynitrite." FEBS Lett 398(2-3): 179-182. PMID: 8977102

Masumoto, H. and H. Sies (1996). "The reaction of ebselen with peroxynitrite." Chem Res Toxicol 9(1): 262-267. PMID: 8924601

Masumoto, H. and H. Sies (1996). "The reaction of 2-(methylseleno)benzanilide with peroxynitrite." Chem Res Toxicol 9(7): 1057-1062. PMID: 8902259

Muschen, M., H. Sies and W. A. Schulz (1996). "Induction of mouse embryonal carcinoma cell differentiation and activation of the retinoic acid receptor beta 2 promoter by 1,25-dihydroxyvitamin D3." Biol Chem 377(11): 703-710. PMID: 8960371

Roussyn, I., K. Briviba, H. Masumoto and H. Sies (1996). "Selenium-containing compounds protect DNA from single-strand breaks caused by peroxynitrite." Arch Biochem Biophys 330(1): 216-218. PMID: 8651699

Schulz, W. A., P. Eickelmann and H. Sies (1996). "Free radicals in toxicology: redox cycling and NAD(P)H:quinone oxidoreductase." Arch Toxicol Suppl 18: 217-222. PMID: 8678798

Sharov, V. S., K. Briviba and H. Sies (1996). "Assessment of the C-525 laser dye as a chemiluminescence sensitizer for lipid peroxidation in biological membranes: a comparison with chlorophyll-a." Free Radic Biol Med 21(6): 833-843. PMID: 8902529

Sies, H., W. A. Schulz and S. Steenken (1996). "Adjacent guanines as preferred sites for strand breaks in plasmid DNA irradiated with 193 nm and 248 nm UV laser light." J Photochem Photobiol B 32(1-2): 97-102. PMID: 8725057

Stahl, W. and H. Sies (1996). "Lycopene: a biologically important carotenoid for humans?" Arch Biochem Biophys 336(1): 1-9. PMID: 8951028

Stahl, W., M. Hanusch and H. Sies (1996). "4-oxo-retinoic acid is generated from its precursor canthaxanthin and enhances gap junctional communication in 10T1/2 cells." Adv Exp Med Biol 387: 121-128. PMID: 8794203

Traber, M. G. and H. Sies (1996). "Vitamin E in humans: demand and delivery." Annu Rev Nutr 16: 321-347. PMID: 8839930

von Herbay, A., W. Stahl, C. Niederau, J. von Laar, G. Strohmeyer and H. Sies (1996). "Diminished plasma levels of vitamin E in patients with severe viral hepatitis." Free Radic Res 25(6): 461-466. PMID: 8951419

von Laar, J., W. Stahl, K. Bolsen, G. Goerz and H. Sies (1996). "Beta-carotene serum levels in patients with erythropoietic protoporphyria on treatment with the synthetic all-trans isomer or a natural isomeric mixture of beta-carotene." J Photochem Photobiol B 33(2): 157-162. PMID: 8691357

Akerboom, T. P., H. Sies and D. M. Ziegler (1995). "The oxidation of ebselen metabolites to thiol oxidants catalyzed by liver microsomes and perfused rat liver." Arch Biochem Biophys 316(1): 220-226. PMID: 7840620

Antonenkov, V. D. and H. Sies (1995). "Some basic properties of ascorbate-dependent antioxidative-defence factors from rat liver cytosol." Chem Biol Interact 94(3): 169-181. PMID: 7820882

Eickelmann, P., F. Morel, W. A. Schulz and H. Sies (1995). "Turnover of glutathione S-transferase alpha mRNAs is accelerated by 12-O-tetradecanoyl phorbol-13-acetate in human hepatoma and colon carcinoma cell lines." Eur J Biochem 229(1): 21-26. PMID: 7744032

Hanusch, M., W. Stahl, W. A. Schulz and H. Sies (1995). "Induction of gap junctional communication by 4-oxoretinoic acid generated from its precursor canthaxanthin." Arch Biochem Biophys 317(2): 423-428. PMID: 7893159

Muller-Breitkreutz, K., H. Mohr, K. Briviba and H. Sies (1995). "Inactivation of viruses by chemically and photochemically generated singlet molecular oxygen." J Photochem Photobiol B 30(1): 63-70. PMID: 8558363

Nikawa, T., W. A. Schulz, C. E. van den Brink, M. Hanusch, P. van der Saag, W. Stahl and H. Sies (1995). "Efficacy of all-trans-beta-carotene, canthaxanthin, and all-trans-, 9-cis-, and 4-oxoretinoic acids in inducing differentiation of an F9 embryonal carcinoma RAR beta-lacZ reporter cell line." Arch Biochem Biophys 316(2): 665-672. PMID: 7864621

Sies, H. and W. Stahl (1995). "Vitamins E and C, beta-carotene, and other carotenoids as antioxidants." Am J Clin Nutr 62(6 Suppl): 1315S-1321S. PMID: 7495226

Sies, H. and N. I. Krinsky (1995). "The present status of antioxidant vitamins and beta-carotene." Am J Clin Nutr 62(6 Suppl): 1299S-1300S. PMID: 7495222

Sies, H. (1995). "Ebselen." Methods Enzymol 252: 341-342. PMID: 7476371

Soboll, S., S. Grundel, J. Harris, V. Kolb-Bachofen, B. Ketterer and H. Sies (1995). "The content of glutathione and glutathione S-transferases and the glutathione peroxidase activity in rat liver nuclei determined by a non-aqueous technique of cell fractionation." Biochem J 311 ( Pt 3): 889-894. PMID: 7487946

Stahl, W., W. Schwarz, J. von Laar and H. Sies (1995). "All-trans beta-carotene preferentially accumulates in human chylomicrons and very low density lipoproteins compared with the 9-cis geometrical isomer." J Nutr 125(8): 2128-2133. PMID: 7643247

Stremmel, W., H. de Groot, H. Sies and G. Strohmeyer (1995). "[Mechanism of liver damage. Pathogenesis of primary hemochromatosis and auxiliary liver transplantation]." Internist (Berl) 36(4): 362-366. PMID: 7775085

Wingerath, T., W. Stahl and H. Sies (1995). "beta-Cryptoxanthin selectively increases in human chylomicrons upon ingestion of tangerine concentrate rich in beta-cryptoxanthin esters." Arch Biochem Biophys 324(2): 385-390. PMID: 8554331

Wlaschek, M., K. Briviba, G. P. Stricklin, H. Sies and K. Scharffetter-Kochanek (1995). "Singlet oxygen may mediate the ultraviolet A-induced synthesis of interstitial collagenase." J Invest Dermatol 104(2): 194-198. PMID: 7829875

Akerboom, T. P. and H. Sies (1994). "Transport of glutathione disulfide and glutathione S-conjugates in hepatocyte plasma membrane vesicles." Methods Enzymol 233: 416-425. PMID: 8015477

Christison, J., H. Sies and R. Stocker (1994). "Human blood cells support the reduction of low-density-lipoprotein-associated cholesteryl ester hydroperoxides by albumin-bound ebselen." Biochem J 304 ( Pt 2): 341-345. PMID: 7998966

Clairmont, A., T. Ebert, H. Weber, C. Zoidl, P. Eickelmann, W. A. Schulz, H. Sies and G. U. Ryffel (1994). "Lowered amounts of the tissue-specific transcription factor LFB1 (HNF1) correlate with decreased levels of glutathione S-transferase alpha messenger RNA in human renal cell carcinoma." Cancer Res 54(5): 1319-1323. PMID: 8118822

Di Mascio, P., E. J. Bechara, M. H. Medeiros, K. Briviba and H. Sies (1994). "Singlet molecular oxygen production in the reaction of peroxynitrite with hydrogen peroxide." FEBS Lett 355(3): 287-289. PMID: 7988691

Eickelmann, P., T. Ebert, U. Warskulat, W. A. Schulz and H. Sies (1994). "Expression of NAD(P)H:quinone oxidoreductase and glutathione S-transferases alpha and pi in human renal cell carcinoma and in kidney cancer-derived cell lines." Carcinogenesis 15(2): 219-225. PMID: 8313512

Eickelmann, P., W. A. Schulz, D. Rohde, B. Schmitz-Drager and H. Sies (1994). "Loss of heterozygosity at the NAD(P)H: quinone oxidoreductase locus associated with increased resistance against mitomycin C in a human bladder carcinoma cell line." Biol Chem Hoppe Seyler 375(7): 439-445. PMID: 7945992

Horakova, L., H. Sies and S. Steenken (1994). "Antioxidant action of stobadine." Methods Enzymol 234: 572-580. PMID: 7808333

Horbach, M. E., H. Sies and T. P. Akerboom (1994). "Purification of rat liver plasma membrane glutathione transferase." Eur J Biochem 222(1): 91-96. PMID: 8200358

Medeiros, M. H., P. Di Mascio, S. Grundel, S. Soboll, H. Sies and E. J. Bechara (1994). "Catabolism of 5-aminolevulinic acid to CO2 by rat liver mitochondria." Arch Biochem Biophys 310(1): 205-209. PMID: 8161206

Morel, F., W. A. Schulz and H. Sies (1994). "Gene structure and regulation of expression of human glutathione S-transferases alpha." Biol Chem Hoppe Seyler 375(10): 641-649. PMID: 7888077

Nikawa, T., G. Schuch, G. Wagner and H. Sies (1994). "Interaction of albumin-bound ebselen with rat liver glutathione S-transferase and microsomal proteins." Biochem Mol Biol Int 32(2): 291-298. PMID: 8019434

Nikawa, T., G. Schuch, G. Wagner and H. Sies (1994). "Interaction of ebselen with glutathione S-transferase and papain in vitro." Biochem Pharmacol 47(6): 1007-1012. PMID: 8147899

Schulz, W. A., M. S. Obendorf and H. Sies (1994). "Localization of strand breaks in plasmid DNA treated with reactive oxygen species." Methods Enzymol 234: 45-51. PMID: 7808318

Sies, H. (1994). "Ebselen: a glutathione peroxidase mimic." Methods Enzymol 234: 476-482. PMID: 7808321

Stahl, W., S. Nicolai, M. Hanusch and H. Sies (1994). "Vitamin D influences gap junctional communication in C3H/10T 1/2 murine fibroblast cells." FEBS Lett 352(1): 1-3. PMID: 7925930

Stahl, W. and H. Sies (1994). "Separation of geometrical isomers of beta-carotene and lycopene." Methods Enzymol 234: 388-400. PMID: 7808311

Sundquist, A. R., K. Briviba and H. Sies (1994). "Singlet oxygen quenching by carotenoids." Methods Enzymol 234: 384-388. PMID: 7808310

von Herbay, A., H. de Groot, U. Hegi, W. Stremmel, G. Strohmeyer and H. Sies (1994). "Low vitamin E content in plasma of patients with alcoholic liver disease, hemochromatosis and Wilson's disease." J Hepatol 20(1): 41-46. PMID: 8201221

Wagner, G., G. Schuch, T. P. Akerboom and H. Sies (1994). "Transport of ebselen in plasma and its transfer to binding sites in the hepatocyte." Biochem Pharmacol 48(6): 1137-1144. PMID: 7945407

Bartosz, G., H. Sies and T. P. Akerboom (1993). "Organic anions exhibit distinct inhibition patterns on the low-Km and high-Km transport of S-(2,4-dinitrophenyl)glutathione through the human erythrocyte membrane." Biochem J 292 ( Pt 1): 171-174. PMID: 8503844

Briviba, K., T. P. Devasagayam, H. Sies and S. Steenken (1993). "Selective para hydroxylation of phenol and aniline by singlet molecular oxygen." Chem Res Toxicol 6(4): 548-553. PMID: 8374055

Briviba, K., G. Fraser, H. Sies and B. Ketterer (1993). "Distribution of the monochlorobimane-glutathione conjugate between nucleus and cytosol in isolated hepatocytes." Biochem J 294 ( Pt 3): 631-633. PMID: 8379916

de Groot, H., U. Hegi and H. Sies (1993). "Loss of alpha-tocopherol upon exposure to nitric oxide or the sydnonimine SIN-1." FEBS Lett 315(2): 139-142. PMID: 8417969

Devasagayam, T. P., M. Subramanian, D. S. Pradhan and H. Sies (1993). "Prevention of singlet oxygen-induced DNA damage by lipoate." Chem Biol Interact 86(1): 79-92. PMID: 8431966

Hansberg, W., H. de Groot and H. Sies (1993). "Reactive oxygen species associated with cell differentiation in Neurospora crassa." Free Radic Biol Med 14(3): 287-293. PMID: 8458586

Horbach, M. E., H. Sies and T. P. Akerboom (1993). "Identification of a hepatic plasma membrane glutathione S-transferase activated by N-ethylmaleimide." Biochim Biophys Acta 1148(1): 61-66. PMID: 8499469

Kagan, V. E., M. Tsuchiya, E. Serbinova, L. Packer and H. Sies (1993). "Interaction of the pyridoindole stobadine with peroxyl, superoxide and chromanoxyl radicals." Biochem Pharmacol 45(2): 393-400. PMID: 8382064

Oarada, M., W. Stahl and H. Sies (1993). "Cellular levels of all-trans-beta-carotene under the influence of 9-cis-beta-carotene in FU-5 rat hepatoma cells." Biol Chem Hoppe Seyler 374(12): 1075-1081. PMID: 8129852

Pung, A., A. Franke, L. X. Zhang, H. Ippendorf, H. D. Martin, H. Sies and J. S. Bertram (1993). "A synthetic C22 carotenoid inhibits carcinogen-induced neoplastic transformation and enhances gap junctional communication." Carcinogenesis 14(5): 1001-1005. PMID: 8504461

Scharffetter-Kochanek, K., M. Wlaschek, K. Briviba and H. Sies (1993). "Singlet oxygen induces collagenase expression in human skin fibroblasts." FEBS Lett 331(3): 304-306. PMID: 8375513

Sies, H. (1993). "Strategies of antioxidant defense." Eur J Biochem 215(2): 213-219. PMID: 7688300

Sies, H. (1993). "Damage to plasmid DNA by singlet oxygen and its protection." Mutat Res 299(3-4): 183-191. PMID: 7683086

Sies, H. (1993). "Ebselen, a selenoorganic compound as glutathione peroxidase mimic." Free Radic Biol Med 14(3): 313-323. PMID: 8458589

Stahl, W., W. Schwarz and H. Sies (1993). "Human serum concentrations of all-trans beta- and alpha-carotene but not 9-cis beta-carotene increase upon ingestion of a natural isomer mixture obtained from Dunaliella salina (Betatene)." J Nutr 123(5): 847-851. PMID: 8487096

Stahl, W., A. R. Sundquist, M. Hanusch, W. Schwarz and H. Sies (1993). "Separation of beta-carotene and lycopene geometrical isomers in biological samples." Clin Chem 39(5): 810-814. PMID: 8485871

Stahl, W. and H. Sies (1993). "Physical quenching of singlet oxygen and cis-trans isomerization of carotenoids." Ann N Y Acad Sci 691: 10-19. PMID: 8129279

Sundquist, A. R., M. Hanusch, W. Stahl and H. Sies (1993). "Cis/trans isomerization of carotenoids by the triplet carbonyl source 3-hydroxymethyl-3,4,4-trimethyl-1,2-dioxetane." Photochem Photobiol 57(5): 785-791. PMID: 8337249

Wagner, J. R., P. A. Motchnik, R. Stocker, H. Sies and B. N. Ames (1993). "The oxidation of blood plasma and low density lipoprotein components by chemically generated singlet oxygen." J Biol Chem 268(25): 18502-18506. PMID: 8360151

Akerboom, T. P., G. Bartosz and H. Sies (1992). "Low- and high-Km transport of dinitrophenyl glutathione in inside out vesicles from human erythrocytes." Biochim Biophys Acta 1103(1): 115-119. PMID: 1730013

Antonenkov, V. D. and H. Sies (1992). "Ascorbate-dependent capacity of dialysed rat liver cytosol to prevent nonenzymatic lipid peroxidation." Biol Chem Hoppe Seyler 373(11): 1111-1116. PMID: 1476660

Devasagayam, T. P., T. Werner, H. Ippendorf, H. D. Martin and H. Sies (1992). "Synthetic carotenoids, novel polyene polyketones and new capsorubin isomers as efficient quenchers of singlet molecular oxygen." Photochem Photobiol 55(4): 511-514. PMID: 1620727

Hasse, A., W. A. Schulz and H. Sies (1992). "De novo methylation of transfected CAT gene plasmid constructs in F9 mouse embryonal carcinoma cells." Biochim Biophys Acta 1131(1): 16-22. PMID: 1581356

Horakova, L., K. Briviba and H. Sies (1992). "Antioxidant activity of the pyridoindole stobadine in liposomal and microsomal lipid peroxidation." Chem Biol Interact 83(1): 85-93. PMID: 1643671

Klone, A., R. Hussnatter and H. Sies (1992). "Cloning, sequencing and characterization of the human alpha glutathione S-transferase gene corresponding to the cDNA clone pGTH2." Biochem J 285 ( Pt 3): 925-928. PMID: 1497629

Murphy, M. E., R. Kolvenbach, M. Aleksis, R. Hansen and H. Sies (1992). "Antioxidant depletion in aortic crossclamping ischemia: increase of the plasma alpha-tocopheryl quinone/alpha-tocopherol ratio." Free Radic Biol Med 13(2): 95-100. PMID: 1516843

Murphy, M. E., H. Scholich and H. Sies (1992). "Protection by glutathione and other thiol compounds against the loss of protein thiols and tocopherol homologs during microsomal lipid peroxidation." Eur J Biochem 210(1): 139-146. PMID: 1446667

Ribeiro, D. T., C. Madzak, A. Sarasin, P. Di Mascio, H. Sies and C. F. Menck (1992). "Singlet oxygen induced DNA damage and mutagenicity in a single-stranded SV40-based shuttle vector." Photochem Photobiol 55(1): 39-45. PMID: 1318549

Sies, H. (1992). "Carotenoids and tocopherols as antioxidants and singlet oxygen quenchers." J Nutr Sci Vitaminol (Tokyo) Spec No: 27-33. PMID: 1297754

Sies, H. and H. de Groot (1992). "Role of reactive oxygen species in cell toxicity." Toxicol Lett 64-65 Spec No: 547-551. PMID: 1335181

Sies, H. and C. F. Menck (1992). "Singlet oxygen induced DNA damage." Mutat Res 275(3-6): 367-375. PMID: 1383777

Sies, H., W. Stahl and A. R. Sundquist (1992). "Antioxidant functions of vitamins. Vitamins E and C, beta-carotene, and other carotenoids." Ann N Y Acad Sci 669: 7-20. PMID: 1444060

Stahl, W., W. Schwarz, A. R. Sundquist and H. Sies (1992). "cis-trans isomers of lycopene and beta-carotene in human serum and tissues." Arch Biochem Biophys 294(1): 173-177. PMID: 1550343

Stahl, W. and H. Sies (1992). "Uptake of lycopene and its geometrical isomers is greater from heat-processed than from unprocessed tomato juice in humans." J Nutr 122(11): 2161-2166. PMID: 1432255

Steenken, S., A. R. Sundquist, S. V. Jovanovic, R. Crockett and H. Sies (1992). "Antioxidant activity of the pyridoindole stobadine. Pulse radiolytic characterization of one-electron-oxidized stobadine and quenching of singlet molecular oxygen." Chem Res Toxicol 5(3): 355-360. PMID: 1504258

Strohmeyer, T., A. Klone, G. Wagner, M. Hartmann and H. Sies (1992). "Glutathione S-transferases in human testicular germ cell tumors: changes of expression and activity." J Urol 147(5): 1424-1428. PMID: 1314914

Wang, J. F., P. Komarov, H. Sies and H. de Groot (1992). "Inhibition of superoxide and nitric oxide release and protection from reoxygenation injury by Ebselen in rat Kupffer cells." Hepatology 15(6): 1112-1116. PMID: 1375578

Ziegler, D. M., P. Graf, L. L. Poulsen, W. Stahl and H. Sies (1992). "NADPH-dependent oxidation of reduced ebselen, 2-selenylbenzanilide, and of 2-(methylseleno)benzanilide catalyzed by pig liver flavin-containing monooxygenase." Chem Res Toxicol 5(2): 163-166. PMID: 1643246

Akerboom, T., I. Schneider, S. vom Dahl and H. Sies (1991). "Cholestasis and changes of portal pressure caused by chlorpromazine in the perfused rat liver." Hepatology 13(2): 216-221. PMID: 1899850

Akerboom, T. P., V. Narayanaswami, M. Kunst and H. Sies (1991). "ATP-dependent S-(2,4-dinitrophenyl)glutathione transport in canalicular plasma membrane vesicles from rat liver." J Biol Chem 266(20): 13147-13152. PMID: 2071597

Chai, Y. C., C. H. Jung, C. K. Lii, S. S. Ashraf, S. Hendrich, B. Wolf, H. Sies and J. A. Thomas (1991). "Identification of an abundant S-thiolated rat liver protein as carbonic anhydrase III; characterization of S-thiolation and dethiolation reactions." Arch Biochem Biophys 284(2): 270-278. PMID: 1899179

Devasagayam, T. P., S. Steenken, M. S. Obendorf, W. A. Schulz and H. Sies (1991). "Formation of 8-hydroxy(deoxy)guanosine and generation of strand breaks at guanine residues in DNA by singlet oxygen." Biochemistry 30(25): 6283-6289. PMID: 2059635

Devasagayam, T. P., A. R. Sundquist, P. Di Mascio, S. Kaiser and H. Sies (1991). "Activity of thiols as singlet molecular oxygen quenchers." J Photochem Photobiol B 9(1): 105-116. PMID: 1907641

Devasagayam, T. P., P. Di Mascio, S. Kaiser and H. Sies (1991). "Singlet oxygen induced single-strand breaks in plasmid pBR322 DNA: the enhancing effect of thiols." Biochim Biophys Acta 1088(3): 409-412. PMID: 2015303

Di Mascio, P., M. E. Murphy and H. Sies (1991). "Antioxidant defense systems: the role of carotenoids, tocopherols, and thiols." Am J Clin Nutr 53(1 Suppl): 194S-200S. PMID: 1985387

Di Mascio, P., S. P. Kaiser, T. P. Devasagayam and H. Sies (1991). "Biological significance of active oxygen species: in vitro studies on singlet oxygen-induced DNA damage and on the singlet oxygen quenching ability of carotenoids, tocopherols and thiols." Adv Exp Med Biol 283: 71-77. PMID: 2069044

Murphy, M. E. and H. Sies (1991). "Reversible conversion of nitroxyl anion to nitric oxide by superoxide dismutase." Proc Natl Acad Sci U S A 88(23): 10860-10864. PMID: 1961756

Murphy, M. E., H. M. Piper, H. Watanabe and H. Sies (1991). "Nitric oxide production by cultured aortic endothelial cells in response to thiol depletion and replenishment." J Biol Chem 266(29): 19378-19383. PMID: 1918052

Schulz, W. A., P. Eickelmann, C. Hallbrucker, H. Sies and D. Haussinger (1991). "Increase of beta-actin mRNA upon hypotonic perfusion of perfused rat liver." FEBS Lett 292(1-2): 264-266. PMID: 1959616

Sies, H. (1991). "Role of reactive oxygen species in biological processes." Klin Wochenschr 69(21-23): 965-968. PMID: 1798292

Sies, H. (1991). "Oxidative stress: from basic research to clinical application." Am J Med 91(3C): 31S-38S. PMID: 1928209

Sies, H. and M. E. Murphy (1991). "Role of tocopherols in the protection of biological systems against oxidative damage." J Photochem Photobiol B 8(2): 211-218. PMID: 1904922

Wang, J. F., P. Komarov, H. Sies and H. de Groot (1991). "Contribution of nitric oxide synthase to luminol-dependent chemiluminescence generated by phorbol-ester-activated Kupffer cells." Biochem J 279 ( Pt 1): 311-314. PMID: 1718262

Di Mascio, P., C. F. Menck, R. G. Nigro, A. Sarasin and H. Sies (1990). "Singlet molecular oxygen induced mutagenicity in a mammalian SV40-based shuttle vector." Photochem Photobiol 51(3): 293-298. PMID: 2162544

Di Mascio, P., T. P. Devasagayam, S. Kaiser and H. Sies (1990). "Carotenoids, tocopherols and thiols as biological singlet molecular oxygen quenchers." Biochem Soc Trans 18(6): 1054-1056. PMID: 2088803

John, N. J., R. Terlinden, H. Fischer, M. Evers and H. Sies (1990). "Microsomal metabolism of 2-(methylseleno) benzanilide." Chem Res Toxicol 3(3): 199-203. PMID: 2131831

Kaiser, S., P. Di Mascio, M. E. Murphy and H. Sies (1990). "Physical and chemical scavenging of singlet molecular oxygen by tocopherols." Arch Biochem Biophys 277(1): 101-108. PMID: 2306113

Kaiser, S., P. Di Mascio, M. E. Murphy and H. Sies (1990). "Quenching of singlet molecular oxygen by tocopherols." Adv Exp Med Biol 264: 117-124. PMID: 2173868

Klone, A., U. Weidner, R. Hussnatter, J. Harris, D. Meyer, S. Peter, B. Ketterer and H. Sies (1990). "Decreased expression of the glutathione S-transferases alpha and pi genes in human renal cell carcinoma." Carcinogenesis 11(12): 2179-2183. PMID: 2265470

Meier, B., H. H. Radeke, S. Selle, H. H. Raspe, H. Sies, K. Resch and G. G. Habermehl (1990). "Human fibroblasts release reactive oxygen species in response to treatment with synovial fluids from patients suffering from arthritis." Free Radic Res Commun 8(3): 149-160. PMID: 2158476

Meier, B., H. H. Radeke, S. Selle, G. G. Habermehl, K. Resch and H. Sies (1990). "Human fibroblasts release low amounts of reactive oxygen species in response to the potent phagocyte stimulants, serum-treated zymosan, N-formyl-methionyl-leucyl-phenylalanine, leukotriene B4 or 12-O-tetradecanoylphorbol 13-acetate." Biol Chem Hoppe Seyler 371(10): 1021-1025. PMID: 1963784

Miller, R. M., H. Sies, E. M. Park and J. A. Thomas (1990). "Phosphorylase and creatine kinase modification by thiol-disulfide exchange and by xanthine oxidase-initiated S-thiolation." Arch Biochem Biophys 276(2): 355-363. PMID: 2106288

Murphy, M. E. and H. Sies (1990). "Visible-range low-level chemiluminescence in biological systems." Methods Enzymol 186: 595-610. PMID: 2233321

Narayanaswami, V. and H. Sies (1990). "Oxidative damage to mitochondria and protection by ebselen and other antioxidants." Biochem Pharmacol 40(7): 1623-1629. PMID: 2171535

Narayanaswami, V. and H. Sies (1990). "Antioxidant activity of ebselen and related selenoorganic compounds in microsomal lipid peroxidation." Free Radic Res Commun 10(4-5): 237-244. PMID: 2289694

Pau, H., P. Graf and H. Sies (1990). "Glutathione levels in human lens: regional distribution in different forms of cataract." Exp Eye Res 50(1): 17-20. PMID: 2307192

Scheschonka, A., M. E. Murphy and H. Sies (1990). "Temporal relationships between the loss of vitamin E, protein sulfhydryls and lipid peroxidation in microsomes challenged with different prooxidants." Chem Biol Interact 74(3): 233-252. PMID: 2347003

Schoneich, C., V. Narayanaswami, K. D. Asmus and H. Sies (1990). "Reactivity of ebselen and related selenoorganic compounds with 1,2-dichloroethane radical cations and halogenated peroxyl radicals." Arch Biochem Biophys 282(1): 18-25. PMID: 2221918

Weidner, U., S. Peter, T. Strohmeyer, R. Hussnatter, R. Ackermann and H. Sies (1990). "Inverse relationship of epidermal growth factor receptor and HER2/neu gene expression in human renal cell carcinoma." Cancer Res 50(15): 4504-4509. PMID: 1973362

Akerboom, T. P. and H. Sies (1989). "Transport of glutathione, glutathione disulfide, and glutathione conjugates across the hepatocyte plasma membrane." Methods Enzymol 173: 523-534. PMID: 2779439

Benedetti, A., P. Graf, R. Fulceri, A. Romani and H. Sies (1989). "Ca2+ mobilization by vasopressin and glucagon in perfused livers. Effect of prior intoxication with bromotrichloromethane." Biochem Pharmacol 38(11): 1799-1805. PMID: 2735938

Cadenas, E., M. G. Simic and H. Sies (1989). "Antioxidant activity of 5-hydroxytryptophan, 5-hydroxyindole, and DOPA against microsomal lipid peroxidation and its dependence on vitamin E." Free Radic Res Commun 6(1): 11-17. PMID: 2498167

De Groot, H. and H. Sies (1989). "Cytochrome P-450, reductive metabolism, and cell injury." Drug Metab Rev 20(2-4): 275-284. PMID: 2680385

Di Mascio, P., H. Wefers, H. P. Do-Thi, M. V. Lafleur and H. Sies (1989). "Singlet molecular oxygen causes loss of biological activity in plasmid and bacteriophage DNA and induces single-strand breaks." Biochim Biophys Acta 1007(2): 151-157. PMID: 2920171

Di Mascio, P., S. Kaiser and H. Sies (1989). "Lycopene as the most efficient biological carotenoid singlet oxygen quencher." Arch Biochem Biophys 274(2): 532-538. PMID: 2802626

Dutta, S., M. Zimmer, H. Sies, R. W. Carlson, W. J. Cullen and J. W. Thayer (1989). "Comparative toxicology of ozone and t-butyl hydroperoxide on isolated rat lung." Free Radic Res Commun 8(1): 27-35. PMID: 2583555

Kuhn-Velten, N. and H. Sies (1989). "Optical spectral studies of ebselen interaction with cytochrome P-450 of rat liver microsomes." Biochem Pharmacol 38(4): 619-625. PMID: 2917017

Kunst, M., H. Sies and T. P. Akerboom (1989). "S-(4-azidophenacyl)[35S]glutathione photoaffinity labeling of rat liver plasma membrane-associated proteins." Biochim Biophys Acta 982(1): 15-23. PMID: 2742884

Kunst, M., H. Sies and T. P. Akerboom (1989). "ATP-stimulated uptake of S-(2,4-dinitrophenyl)glutathione by plasma membrane vesicles from rat liver." Biochim Biophys Acta 983(1): 123-125. PMID: 2758047

Medeiros, M. H. and H. Sies (1989). "Chemiluminescent oxidation of ribose catalyzed by horseradish peroxidase in presence of hydrogen peroxide." Free Radic Biol Med 6(6): 565-571. PMID: 2502483

Meier, B., H. H. Radeke, S. Selle, M. Younes, H. Sies, K. Resch and G. G. Habermehl (1989). "Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-alpha." Biochem J 263(2): 539-545. PMID: 2556998

Peinado, J., H. Sies and T. P. Akerboom (1989). "Hepatic lipoate uptake." Arch Biochem Biophys 273(2): 389-395. PMID: 2505669

Rokutan, K., J. A. Thomas and H. Sies (1989). "Specific S-thiolation of a 30-kDa cytosolic protein from rat liver under oxidative stress." Eur J Biochem 179(1): 233-239. PMID: 2917563

Scholich, H., M. E. Murphy and H. Sies (1989). "Antioxidant activity of dihydrolipoate against microsomal lipid peroxidation and its dependence on alpha-tocopherol." Biochim Biophys Acta 1001(3): 256-261. PMID: 2492825

Schulte-Herbruggen, T. and H. Sies (1989). "The peroxidase/oxidase activity of soybean lipoxygenase--I. Triplet excited carbonyls from the reaction with isobutanal and the effect of glutathione." Photochem Photobiol 49(5): 697-704. PMID: 2502778

Schulte-Herbruggen, T. and H. Sies (1989). "The peroxidase/oxidase activity of soybean lipoxygenase--II. Triplet carbonyls and red photoemission during polyunsaturated fatty acid and glutathione oxidation." Photochem Photobiol 49(5): 705-710. PMID: 2502779

Sies, H. (1989). "[Biochemistry of thiol groups: the role of glutathione]." Naturwissenschaften 76(2): 57-64. PMID: 2657438

Sies, H. (1989). "Relationship between free radicals and vitamins: an overview." Int J Vitam Nutr Res Suppl 30: 215-223. PMID: 2507700

Soboll, S. and H. Sies (1989). "Effects of hormones on mitochondrial processes." Methods Enzymol 174: 118-130. PMID: 2576681

Akerboom, T., T. Bultmann and H. Sies (1988). "Inhibition of biliary taurocholate excretion during menadione metabolism in perfused rat liver." Arch Biochem Biophys 263(1): 10-18. PMID: 3369854

Dutta, S., A. Muller, T. Ishikawa, M. Zimmer and H. Sies (1988). "Alkane production by isolated rat heart and lung." Toxicol Lett 44(1-2): 55-64. PMID: 3188082

Kehrer, J. P., Y. Park and H. Sies (1988). "Energy dependence of enzyme release from hypoxic isolated perfused rat heart tissue." J Appl Physiol (1985) 65(4): 1855-1860. PMID: 3182545

Knoblauch, A. L., A. Paky, J. R. Michael, M. E. Kutner, E. Cadenas, H. Sies, N. F. Adkinson, Jr. and G. H. Gurtner (1988). "Hydroperoxide-induced chemiluminescence in rabbit lungs: role of arachidonic acid enzymes." J Appl Physiol (1985) 65(3): 1340-1350. PMID: 3141352

Muller, A., H. Gabriel, H. Sies, R. Terlinden, H. Fischer and A. Romer (1988). "A novel biologically active selenooorganic compound--VII. Biotransformation of ebselen in perfused rat liver." Biochem Pharmacol 37(6): 1103-1109. PMID: 3355585

vom Dahl, S., P. Graf and H. Sies (1988). "Hepatic inositol release upon hormonal stimulation of perfused rat liver." Biochem J 251(3): 843-848. PMID: 2843165

Wagner, G., U. Pott, M. Bruckschen and H. Sies (1988). "Effects of 5-azacytidine and methyl-group deficiency on NAD(P)H: quinone oxidoreductase and glutathione S-transferase in liver." Biochem J 251(3): 825-829. PMID: 2458098

Wefers, H., P. Di Mascio, H. P. Do-Thi, D. Schulte-Frohlinde and H. Sies (1988). "Effects of singlet oxygen on the biological activity of DNA and its involvement in single strand-break formation." Basic Life Sci 49: 473-477. PMID: 3250505

Wefers, H. and H. Sies (1988). "The protection by ascorbate and glutathione against microsomal lipid peroxidation is dependent on vitamin E." Eur J Biochem 174(2): 353-357. PMID: 3383850

Akerboom, T., R. Lenzen, I. Schneider and H. Sies (1987). "Cholestasis and changes in the microcirculation of perfused rat liver caused by the calcium ionophore A23187 and type I antiarrhythmic drugs." Biochem Pharmacol 36(18): 3037-3042. PMID: 3115270

Graf, P., S. vom Dahl and H. Sies (1987). "Sustained oscillations in extracellular calcium concentrations upon hormonal stimulation of perfused rat liver." Biochem J 241(3): 933-936. PMID: 3036078

Griffiths, J. C., H. Sies, P. J. Meier and T. P. Akerboom (1987). "Inhibition of taurocholate efflux from rat hepatic canalicular membrane vesicles by glutathione disulfide." FEBS Lett 213(1): 34-38. PMID: 3556579

Haussinger, D., T. Stehle, W. Gerok and H. Sies (1987). "Perivascular nerve stimulation and phenylephrine responses in rat liver. Metabolic effects, Ca2+ and K+ fluxes." Eur J Biochem 163(1): 197-203. PMID: 3816798

Kehrer, J. P., H. M. Piper and H. Sies (1987). "Xanthine oxidase is not responsible for reoxygenation injury in isolated-perfused rat heart." Free Radic Res Commun 3(1-5): 69-78. PMID: 3508444

Lenzen, C., S. Soboll, H. Sies and D. Haussinger (1987). "pH control of hepatic glutamine degradation. Role of transport." Eur J Biochem 166(2): 483-488. PMID: 3609022

Medeiros, M. H., H. Wefers and H. Sies (1987). "Generation of excited species catalyzed by horseradish peroxidase or hemin in the presence of reduced glutathione and H2O2." Free Radic Biol Med 3(2): 107-110. PMID: 3666514

Muller, A. and H. Sies (1987). "Alcohol, aldehydes and lipid peroxidation: current notions." Alcohol Alcohol Suppl 1: 67-74. PMID: 3426749

Napetschnig, S. and H. Sies (1987). "Generation of photoemissive species by mitomycin C redox cycling in rat liver microsomes." Biochem Pharmacol 36(10): 1617-1621. PMID: 3109425

Noll, T., H. de Groot and H. Sies (1987). "Distinct temporal relation among oxygen uptake, malondialdehyde formation, and low-level chemiluminescence during microsomal lipid peroxidation." Arch Biochem Biophys 252(1): 284-291. PMID: 3813537

Prochaska, H. J., P. Talalay and H. Sies (1987). "Direct protective effect of NAD(P)H:quinone reductase against menadione-induced chemiluminescence of postmitochondrial fractions of mouse liver." J Biol Chem 262(5): 1931-1934. PMID: 2434474

Sies, H. (1987). "Intracellular and intercellular liver heterogeneity: an overview." Biochem Soc Trans 15(3): 359-360. PMID: 3622914

Sies, H. (1987). "Antioxidant activity in cells and organs." Am Rev Respir Dis 136(2): 478-480. PMID: 3619212

Sies, H., R. Brigelius and P. Graf (1987). "Hormones, glutathione status and protein S-thiolation." Adv Enzyme Regul 26: 175-189. PMID: 3673705

Sies, H. (1987). "Intact organ spectrophotometry and single-photon counting." Arch Toxicol 60(1-3): 138-143. PMID: 3304203

Storz, G., M. F. Christman, H. Sies and B. N. Ames (1987). "Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium." Proc Natl Acad Sci U S A 84(24): 8917-8921. PMID: 3321061

Wefers, H., D. Schulte-Frohlinde and H. Sies (1987). "Loss of transforming activity of plasmid DNA (pBR322) in E. coli caused by singlet molecular oxygen." FEBS Lett 211(1): 49-52. PMID: 3026841

Graf, P. and H. Sies (1986). "Hepatic glutathione release upon decreases of extracellular calcium concentration." Biochem Pharmacol 35(16): 2832-2833. PMID: 3741471

Haussinger, D., W. Gerok and H. Sies (1986). "The effect of urea synthesis on extracellular pH in isolated perfused rat liver." Biochem J 236(1): 261-265. PMID: 3790075

Hebisch, S., H. Sies and S. Soboll (1986). "Function dependent changes in the subcellular distribution of high energy phosphates in fast and slow rat skeletal muscles." Pflugers Arch 406(1): 20-24. PMID: 3951965

Ishikawa, T., M. Zimmer and H. Sies (1986). "Energy-linked cardiac transport system for glutathione disulfide." FEBS Lett 200(1): 128-132. PMID: 3699157

Ishikawa, T., U. Milbert, F. Oesch and H. Sies (1986). "The major isozyme of rat cardiac glutathione transferases. Its correspondence to hepatic transferase X." Eur J Biochem 154(2): 299-305. PMID: 3080315

Ishikawa, T., H. Esterbauer and H. Sies (1986). "Role of cardiac glutathione transferase and of the glutathione S-conjugate export system in biotransformation of 4-hydroxynonenal in the heart." J Biol Chem 261(4): 1576-1581. PMID: 3753704

Ross, D., P. Moldeus, H. Sies and M. T. Smith (1986). "Mechanism and relevance of glutathione mutagenicity." Mutat Res 175(3): 127-131. PMID: 2877394

Sies, H. and R. Mehlhorn (1986). "Mutagenicity of nitroxide-free radicals." Arch Biochem Biophys 251(1): 393-396. PMID: 3539021

Wefers, H. and H. Sies (1986). "Generation of photoemissive species during quinone redox cycling." Biochem Pharmacol 35(1): 22-24. PMID: 2416319

Wefers, H. and H. Sies (1986). "Reactive oxygen species formed in vitro and in cells: role of thiols (GSH). Model studies with xanthine oxidase and horseradish peroxidase." Adv Exp Med Biol 197: 505-512. PMID: 3766277

Cadenas, E. and H. Sies (1985). "Oxidative stress: excited oxygen species and enzyme activity." Adv Enzyme Regul 23: 217-237. PMID: 3907304

de Groot, H., T. Noll and H. Sies (1985). "Oxygen dependence and subcellular partitioning of hepatic menadione-mediated oxygen uptake. Studies with isolated hepatocytes, mitochondria, and microsomes from rat liver in an oxystat system." Arch Biochem Biophys 243(2): 556-562. PMID: 2417562

Haussinger, D., S. Soboll, A. J. Meijer, W. Gerok, J. M. Tager and H. Sies (1985). "Role of plasma membrane transport in hepatic glutamine metabolism." Eur J Biochem 152(3): 597-603. PMID: 2865140

Haussinger, D., H. Sies and W. Gerok (1985). "Functional hepatocyte heterogeneity in ammonia metabolism. The intercellular glutamine cycle." J Hepatol 1(1): 3-14. PMID: 2865284

Muller, A., H. Gabriel and H. Sies (1985). "A novel biologically active selenoorganic compound--IV. Protective glutathione-dependent effect of PZ 51 (ebselen) against ADP-Fe induced lipid peroxidation in isolated hepatocytes." Biochem Pharmacol 34(8): 1185-1189. PMID: 3994741

Sies, H. and P. Graf (1985). "Hepatic thiol and glutathione efflux under the influence of vasopressin, phenylephrine and adrenaline." Biochem J 226(2): 545-549. PMID: 3994671

Sies, H. and E. Cadenas (1985). "Oxidative stress: damage to intact cells and organs." Philos Trans R Soc Lond B Biol Sci 311(1152): 617-631. PMID: 2869521

Sohal, R. S., A. Muller, B. Koletzko and H. Sies (1985). "Effect of age and ambient temperature on n-pentane production in adult housefly, Musca domestica." Mech Ageing Dev 29(3): 317-326. PMID: 3990386

Wagner, G., H. Frenzel, H. Wefers and H. Sies (1985). "Lack of effect of long-term glutathione administration on aflatoxin B1-induced hepatoma in male rats." Chem Biol Interact 53(1-2): 57-68. PMID: 3922636

Wefers, H., E. Riechmann and H. Sies (1985). "Excited species generation in horseradish peroxidase-mediated oxidation of glutathione." J Free Radic Biol Med 1(4): 311-318. PMID: 3013981

Akerboom, T., M. Inoue, H. Sies, R. Kinne and I. M. Arias (1984). "Biliary transport of glutathione disulfide studied with isolated rat-liver canalicular-membrane vesicles." Eur J Biochem 141(1): 211-215. PMID: 6723660

Akerboom, T. P., M. Bilzer and H. Sies (1984). "Relation between glutathione redox changes and biliary excretion of taurocholate in perfused rat liver." J Biol Chem 259(9): 5838-5843. PMID: 6715375

Bilzer, M., R. L. Krauth-Siegel, R. H. Schirmer, T. P. Akerboom, H. Sies and G. E. Schulz (1984). "Interaction of a glutathione S-conjugate with glutathione reductase. Kinetic and X-ray crystallographic studies." Eur J Biochem 138(2): 373-378. PMID: 6697994

Cadenas, E., M. Ginsberg, U. Rabe and H. Sies (1984). "Evaluation of alpha-tocopherol antioxidant activity in microsomal lipid peroxidation as detected by low-level chemiluminescence." Biochem J 223(3): 755-759. PMID: 6508739

Cadenas, E. and H. Sies (1984). "Low-level chemiluminescence as an indicator of singlet molecular oxygen in biological systems." Methods Enzymol 105: 221-231. PMID: 6328183

Graf, P. and H. Sies (1984). "Hepatic uptake of cadmium and its biliary release as affected by dithioerythritol and glutathione." Biochem Pharmacol 33(4): 639-643. PMID: 6704180

Haussinger, D. and H. Sies (1984). "Effect of phenylephrine on glutamate and glutamine metabolism in isolated perfused rat liver." Biochem J 221(3): 651-658. PMID: 6148074

Hebisch, S., S. Soboll, M. Schwenen and H. Sies (1984). "Compartmentation of high-energy phosphates in resting and working rat skeletal muscle." Biochim Biophys Acta 764(2): 117-124. PMID: 6696884

Inoue, M., T. P. Akerboom, H. Sies, R. Kinne, T. Thao and I. M. Arias (1984). "Biliary transport of glutathione S-conjugate by rat liver canalicular membrane vesicles." J Biol Chem 259(8): 4998-5002. PMID: 6715333

Ishikawa, T. and H. Sies (1984). "The isozyme pattern of glutathione S-transferases in rat heart." FEBS Lett 169(2): 156-160. PMID: 6714423

Ishikawa, T. and H. Sies (1984). "Cardiac transport of glutathione disulfide and S-conjugate. Studies with isolated perfused rat heart during hydroperoxide metabolism." J Biol Chem 259(6): 3838-3843. PMID: 6706982

Muller, A. and H. Sies (1984). "Assay of ethane and pentane from isolated organs and cells." Methods Enzymol 105: 311-319. PMID: 6727670

Muller, A., E. Cadenas, P. Graf and H. Sies (1984). "A novel biologically active seleno-organic compound--I. Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (Ebselen)." Biochem Pharmacol 33(20): 3235-3239. PMID: 6487370

Romero, F. J. and H. Sies (1984). "Subcellular glutathione contents in isolated hepatocytes treated with L-buthionine sulfoximine." Biochem Biophys Res Commun 123(3): 1116-1121. PMID: 6487323

Romero, F. J., S. Soboll and H. Sies (1984). "Mitochondrial and cytosolic glutathione after depletion by phorone in isolated hepatocytes." Experientia 40(4): 365-367. PMID: 6714367

Sies, H. and T. P. Akerboom (1984). "Glutathione disulfide (GSSG) efflux from cells and tissues." Methods Enzymol 105: 445-451. PMID: 6727680

Soboll, S., H. J. Seitz, H. Sies, B. Ziegler and R. Scholz (1984). "Effect of long-chain fatty acyl-CoA on mitochondrial and cytosolic ATP/ADP ratios in the intact liver cell." Biochem J 220(2): 371-376. PMID: 6743276

Wefers, H., T. Komai and H. Sies (1984). "Generation of low-level chemiluminescence during the metabolism of 1-naphthol by rat liver microsomes." Biochem Pharmacol 33(24): 4081-4085. PMID: 6210092

Wefers, H., T. Komai, P. Talalay and H. Sies (1984). "Protection against reactive oxygen species by NAD(P)H: quinone reductase induced by the dietary antioxidant butylated hydroxyanisole (BHA). Decreased hepatic low-level chemiluminescence during quinone redox cycling." FEBS Lett 169(1): 63-66. PMID: 6201394

Bartoli, G. M., A. Muller, E. Cadenas and H. Sies (1983). "Antioxidant effect of diethyldithiocarbamate on microsomal lipid peroxidation assessed by low-level chemiluminescence and alkane production." FEBS Lett 164(2): 371-374. PMID: 6317459

Brigelius, R., C. Muckel, T. P. Akerboom and H. Sies (1983). "Identification and quantitation of glutathione in hepatic protein mixed disulfides and its relationship to glutathione disulfide." Biochem Pharmacol 32(17): 2529-2534. PMID: 6615548

Cadenas, E., R. Brigelius and H. Sies (1983). "Paraquat-induced chemiluminescence of microsomal fractions." Biochem Pharmacol 32(1): 147-150. PMID: 6830610

Cadenas, E., H. Sies, W. Nastainczyk and V. Ullrich (1983). "Singlet oxygen formation detected by low-level chemiluminescence during enzymatic reduction of prostaglandin G2 to H2." Hoppe Seylers Z Physiol Chem 364(5): 519-528. PMID: 6409778

Cadenas, E., H. Sies, H. Graf and V. Ullrich (1983). "Oxene donors yield low-level chemiluminescence with microsomes and isolated cytochrome P-450." Eur J Biochem 130(1): 117-121. PMID: 6825683

Cadenas, E., A. Muller, R. Brigelius, H. Esterbauer and H. Sies (1983). "Effects of 4-hydroxynonenal on isolated hepatocytes. Studies on chemiluminescence response, alkane production and glutathione status." Biochem J 214(2): 479-487. PMID: 6688523

Crane, D., D. Haussinger, P. Graf and H. Sies (1983). "Decreased flux through pyruvate dehydrogenase by thiol oxidation during t-butyl hydroperoxide metabolism in perfused rat liver." Hoppe Seylers Z Physiol Chem 364(8): 977-987. PMID: 6629333

Gurtner, G. H., A. Knoblauch, P. L. Smith, H. Sies and N. F. Adkinson (1983). "Oxidant- and lipid-induced pulmonary vasoconstriction mediated by arachidonic acid metabolites." J Appl Physiol Respir Environ Exerc Physiol 55(3): 949-954. PMID: 6688802

Haussinger, D., W. Gerok and H. Sies (1983). "Regulation of flux through glutaminase and glutamine synthetase in isolated perfused rat liver." Biochim Biophys Acta 755(2): 272-278. PMID: 6131695

Haussinger, D., D. Crane, W. Gerok and H. Sies (1983). "Decrease of flux through pyruvate dehydrogenase and branched-chain 2-oxo-acid dehydrogenase by nitrofurantoin in perfused rat liver." Hoppe Seylers Z Physiol Chem 364(10): 1439-1446. PMID: 6416984

Jernstrom, B., R. Brigelius and H. Sies (1983). "Glutathione conjugation of benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydrodiol-9,10-oxide in the perfused rat liver." Chem Biol Interact 44(1-2): 185-193. PMID: 6406080

Muller, A. and H. Sies (1983). "Ethane release during metabolism of aldehydes and monoamines in perfused rat liver." Eur J Biochem 134(3): 599-602. PMID: 6884350

Muller, A. and H. Sies (1983). "Inhibition of ethanol- and aldehyde-induced release of ethane from isolated perfused rat liver by pargyline and disulfiram." Pharmacol Biochem Behav 18 Suppl 1: 429-432. PMID: 6634853

Sies, H., R. Brigelius, H. Wefers, A. Muller and E. Cadenas (1983). "Cellular redox changes and response to drugs and toxic agents." Fundam Appl Toxicol 3(4): 200-208. PMID: 6354819

Sies, H., P. Graf and D. Crane (1983). "Decreased flux through pyruvate dehydrogenase during calcium ion movements induced by vasopressin, alpha-adrenergic agonists and the ionophore A23187 in perfused rat liver." Biochem J 212(2): 271-278. PMID: 6136270

Wefers, H. and H. Sies (1983). "Oxidation of glutathione by the superoxide radical to the disulfide and the sulfonate yielding singlet oxygen." Eur J Biochem 137(1-2): 29-36. PMID: 6317388

Wefers, H. and H. Sies (1983). "Hepatic low-level chemiluminescence during redox cycling of menadione and the menadione-glutathione conjugate: relation to glutathione and NAD(P)H:quinone reductase (DT-diaphorase) activity." Arch Biochem Biophys 224(2): 568-578. PMID: 6191666

Akerboom, T. P., M. Bilzer and H. Sies (1982). "The relationship of biliary glutathione disulfide efflux and intracellular glutathione disulfide content in perfused rat liver." J Biol Chem 257(8): 4248-4252. PMID: 7068633

Akerboom, T. P., M. Bilzer and H. Sies (1982). "Competition between transport of glutathione disulfide (GSSG) and glutathione S-conjugates from perfused rat liver into bile." FEBS Lett 140(1): 73-76. PMID: 7084458

Brigelius, R., R. Lenzen and H. Sies (1982). "Increase in hepatic mixed disulphide and glutathione disulphide levels elicited by paraquat." Biochem Pharmacol 31(8): 1637-1641. PMID: 7092955

Cadenas, E., H. Wefers, A. Muller, R. Brigelius and H. Sies (1982). "Active oxygen metabolites and their action in the hepatocyte. Studies on chemiluminescence responses and alkane production." Agents Actions Suppl 11: 203-216. PMID: 6960650

Cadenas, E. and H. Sies (1982). "Low level chemiluminescence of liver microsomal fractions initiated by tert-butyl hydroperoxide. Relation to microsomal hemoproteins, oxygen dependence, and lipid peroxidation." Eur J Biochem 124(2): 349-356. PMID: 7094917

Crane, D., D. Haussinger and H. Sies (1982). "Rise of coenzyme A-glutathione mixed disulfide during hydroperoxide metabolism in perfused rat liver." Eur J Biochem 127(3): 575-578. PMID: 7173198

Haussinger, D., W. Gerok and H. Sies (1982). "Inhibition of pyruvate dehydrogenase during the metabolism of glutamine and proline in hemoglobin-free perfused rat liver." Eur J Biochem 126(1): 69-76. PMID: 7128587

Muller, A. and H. Sies (1982). "Role of alcohol dehydrogenase activity and the acetaldehyde in ethanol- induced ethane and pentane production by isolated perfused rat liver." Biochem J 206(1): 153-156. PMID: 6751324

Pau, H., P. Graf and H. Sies (1982). "[Glutathione content of the lens in various forms of cataract]." Graefes Arch Clin Exp Ophthalmol 219(3): 140-142. PMID: 6293935

Sies, H., T. P. Akerboom and E. Cadenas (1982). "The role of glutathione in hepatic hydroperoxide metabolism." Biochem Soc Trans 10(2): 79-80. PMID: 7067916

Sies, H., P. Graf, N. Oshino, A. Boveris and B. Chance (1982). "Peroxisomal function in perfused liver as studied by organ photometry." Ann N Y Acad Sci 386: 153-164. PMID: 6124200

1.       Akerboom, T. P. and H. Sies (1981). "Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples." Methods Enzymol 77: 373-382. PMID: 7329314

Akerboom, T. P., M. Gartner and H. Sies (1981). "Cellular hydroperoxide metabolism: the roles of glutathione peroxidases and of catalase in liver." Bull Eur Physiopathol Respir 17 Suppl: 221-227. PMID: 7248573

Cadenas, E., H. Wefers and H. Sies (1981). "Low-level chemiluminescence of isolated hepatocytes." Eur J Biochem 119(3): 531-536. PMID: 7308199

Foerster, E. C., T. Fahrenkemper, U. Rabe, P. Graf and H. Sies (1981). "Peroxisomal fatty acid oxidation as detected by H2O2 production in intact perfused rat liver." Biochem J 196(3): 705-712. PMID: 7317011

Kappus, H. and H. Sies (1981). "Toxic drug effects associated with oxygen metabolism: redox cycling and lipid peroxidation." Experientia 37(12): 1233-1241. PMID: 7035210

Muller, A., P. Graf, A. Wendel and H. Sies (1981). "Ethane production by isolated perfused rat liver: a system to study metabolic effects related to lipid peroxidation." FEBS Lett 126(2): 241-244. PMID: 7238873

Plummer, J. L., B. R. Smith, H. Sies and J. R. Bend (1981). "Chemical depletion of glutathione in vivo." Methods Enzymol 77: 50-59. PMID: 7035795

Schwenke, W. D., S. Soboll, H. J. Seitz and H. Sies (1981). "Mitochondrial and cytosolic ATP/ADP ratios in rat liver in vivo." Biochem J 200(2): 405-408. PMID: 7340839

Sies, H., P. Graf and J. M. Estrela (1981). "Hepatic calcium efflux during cytochrome P-450-dependent drug oxidations at the endoplasmic reticulum in intact liver." Proc Natl Acad Sci U S A 78(6): 3358-3362. PMID: 6943544

Sies, H. (1981). "Measurement of hydrogen peroxide formation in situ." Methods Enzymol 77: 15-20. PMID: 7329298

Boveris, A., H. Sies, E. E. Martino, R. Docampo, J. F. Turrens and A. O. Stoppani (1980). "Deficient metabolic utilization of hydrogen peroxide in Trypanosoma cruzi." Biochem J 188(3): 643-648. PMID: 7008779

Gerstenecker, C. and H. Sies (1980). "Restriction of hexobarbital metabolism by t-butyl hydroperoxide in perfused rat liver." Biochem Pharmacol 29(22): 3112-3113. PMID: 7458966

Haussinger, D., T. P. Akerboom and H. Sies (1980). "The role of pH and the lack of a requirement for hydorgencarbonate in the regulation of hepatic glutamine metabolism." Hoppe Seylers Z Physiol Chem 361(7): 995-101. PMID: 7409750

Koch, O. R., E. Martino, A. Boveris and H. Sies (1980). "Increased biliary glutathione disulfide (GSSG) release in chronically ethanol-treated rats." Adv Exp Med Biol 132: 619-625. PMID: 7191625

Sies, H. and B. Brauser (1980). "Analysis of cellular electron transport systems in liver and other organs by absorbance and fluorescence techniques." Methods Biochem Anal 26: 285-325. PMID: 7392961

Sies, H., A. Wahllander, C. Waydhas, S. Soboll and D. Hoberle (1980). "Functions of intracellular glutathione in hepatic hydroperoxide and drug metabolism and the role of extracellular glutathione." Adv Enzyme Regul 18: 303-320. PMID: 7004130

Soboll, S., T. P. Akerboom, W. D. Schwenke, R. Haase and H. Sies (1980). "Mitochondrial and cytosolic ATP/ADP ratios in isolated hepatocytes. A comparison of the digitonin method and the non-aqueous fractionation procedure." Biochem J 192(3): 951-954. PMID: 7236247

Akerboom, T. P., W. K. Krietsch, G. Kuntz and H. Sies (1979). "Enzymatic measurement of adenine and guanine (plus inosine) triphosphates and diphosphates in isolated cells and the mitochondrial matrix compartment obtained from rat liver." FEBS Lett 105(1): 90-94. PMID: 114422

Chance, B., H. Sies and A. Boveris (1979). "Hydroperoxide metabolism in mammalian organs." Physiol Rev 59(3): 527-605. PMID: 37532

Haberle, D., A. Wahllander and H. Sies (1979). "Assessment of the kidney function in maintenance of plasma glutathione concentration and redox state in anaesthetized rats." FEBS Lett 108(2): 335-340. PMID: 520571

Haussinger, D. and H. Sies (1979). "Hepatic glutamine metabolism under the influence of the portal ammonia concentration in the perfused rat liver." Eur J Biochem 101(1): 179-184. PMID: 510303

Sies, H., O. R. Koch, E. Martino and A. Boveris (1979). "Increased biliary glutathione disulfide release in chronically ethanol-treated rats." FEBS Lett 103(2): 287-290. PMID: 467672

Wahllander, A., S. Soboll, H. Sies, I. Linke and M. Muller (1979). "Hepatic mitochondrial and cytosolic glutathione content and the subcellular distribution of GSH-S-transferases." FEBS Lett 97(1): 138-140. PMID: 761610

Wahllander, A. and H. Sies (1979). "Glutathione S-conjugate formation from 1-chloro-2,4-dinitrobenzene and biliary S-conjugate excretion in the perfused rat liver." Eur J Biochem 96(3): 441-446. PMID: 467417

Waydhas, C., H. Sies and E. L. Stokstad (1979). "Methionine and thyroid hormone effects on 14CO2 exhalation from [dimethylamino-14C]aminopyrine in intact phenobarbital-pretreated rats." FEBS Lett 103(2): 366-369. PMID: 467681

Bartoli, G. M. and H. Sies (1978). "Reduced and oxidized glutathione efflux from liver." FEBS Lett 86(1): 89-91. PMID: 23318

Schwab, H. and H. Sies (1978). "A new organ spectrophotometer for sensitive dual-wavelength absorbance measurement and spectral scanning of intact perfused organs." Hoppe Seylers Z Physiol Chem 359(3): 385-392. PMID: 640584

Sies, H. (1978). "The use of perfusion of liver and other organs for the study of microsomal electron-transport and cytochrome P-450 systems." Methods Enzymol 52: 48-59. PMID: 672651

Sies, H., G. M. Bartoli, R. F. Burk and C. Waydhas (1978). "Glutathione efflux from perfused rat liver after phenobarbital treatment, during drug oxidations, and in selenium deficiency." Eur J Biochem 89(1): 113-118. PMID: 699901

Sies, H. and K. M. Moss (1978). "A role of mitochondrial glutathione peroxidase in modulating mitochondrial oxidations in liver." Eur J Biochem 84(2): 377-383. PMID: 25178

Waydhas, C., K. Weigl and H. Sies (1978). "The disposition of formaldehyde and formate arising from drug N-demethylations dependent on cytochrome P-450 in hepatocytes and in perfused rat liver." Eur J Biochem 89(1): 143-150. PMID: 568065

Sies, H. (1977). "Oxygen gradients during hypoxic steady states in liver. Urate oxidase and cytochrome oxidase as intracellular O2 indicators." Hoppe Seylers Z Physiol Chem 358(8): 1021-1032. PMID: 200541

Sies, H. (1977). "Cytochrome oxidase and urate oxidase as intracellular O2 indicators in studies of O2 gradients during hypoxia in liver." Adv Exp Med Biol 94: 561-566. PMID: 207168

Sies, H. (1977). "Peroxisomal enzymes and oxygen metabolism in liver." Adv Exp Med Biol 78: 51-60. PMID: 19943

Sies, H., T. P. Akerboom and J. M. Tager (1977). "Mitochondrial and cytosolic NADPH systems and isocitrate dehydrogenase indicator metabolites during ureogensis from ammonia in isolated rat hepatocytes." Eur J Biochem 72(2): 301-307. PMID: 13998

Sies, H. and H. Schwab (1977). "Organ absorbance and fluorescence spectrophotometry and its application to oxygen-dependent parameters." Adv Exp Med Biol 94: 119-125. PMID: 613754

Weigl, K. and H. Sies (1977). "Drug oxidations dependent on cytochrome P-450 in isolated hepatocytes. The role of the tricarboxylates and the aminotransferases in NADPH supply." Eur J Biochem 77(2): 401-408. PMID: 19252

Albrecht, G., M. Kiese, H. Sies and N. Weger (1976). "The effect of tris(2-chloroethyl)amine on human hemoglobin." Naunyn Schmiedebergs Arch Pharmacol 294(2): 179-185. PMID: 13312

Herzog, V., H. Sies and F. Miller (1976). "Exocytosis in secretory cells of rat lacrimal gland. Peroxidase release from lobules and isolated cells upon cholinergic stimulation." J Cell Biol 70(3): 692-706. PMID: 956271

Haussinger, D., L. Weiss and H. Sies (1975). "Activation of pyruvate dehydrogenase during metabolism of ammonium ions in hemoglobin-free perfused rat liver." Eur J Biochem 52(3): 421-431. PMID: 1236139

Sies, H., K. H. Summer and T. Bucher (1975). "A process requiring mitochondrial NADPH: urea formation from ammonia." FEBS Lett 54(2): 274-278. PMID: 236928

Sies, H. and K. H. Summer (1975). "Hydroperoxide-metabolizing systems in rat liver." Eur J Biochem 57(2): 503-512. PMID: 1175655

Sies, H. and Grosskopf (1975). "Oxidation of cytochrome b5 by hydroperoxides in rat liver." Eur J Biochem 57(2): 513-520. PMID: 1175656

Sies, H. (1975). "Proceedings: Monooxygenase activity and nicotinamide nucleotide systems in perfused rat liver." Z Klin Chem Klin Biochem 13(8): 376. PMID: 3044

Sies, H., D. Haussinger and M. Grosskopf (1974). "Mitochondrial nicotinamide nucleotide systems: ammonium chloride responses and associated metabolic transitions in hemoglobin-free perfused rat liver." Hoppe Seylers Z Physiol Chem 355(3): 305-320. PMID: 4154891

Sies, H. and D. Haussinger (1974). "Proceedings: Lack of urea formation by rat liver in hydrogen carbonate-free media." Hoppe Seylers Z Physiol Chem 355(10): 1256-1257. PMID: 4461599

Sies, H. (1974). "Biochemistry of the peroxisome in the liver cell." Angew Chem Int Ed Engl 13(11): 706-718. PMID: 4375415

Kuss, E., S. Fernbacher and H. Sies (1973). "Metabolism of estradiol in isolated perfused rat liver." Acta Endocrinol Suppl (Copenh) 173: 1. PMID: 4542102

Oshino, N., B. Chance, H. Sies and T. Bucher (1973). "The role of H 2 O 2 generation in perfused rat liver and the reaction of catalase compound I and hydrogen donors." Arch Biochem Biophys 154(1): 117-131. PMID: 4347674

Sies, H., G. Noack and K. H. Halder (1973). "Carbon-dioxide concentration and the distribution of monocarboxylate and H+ ions between intracellular and extracellular spaces of hemoglobin-free perfused rat liver." Eur J Biochem 38(2): 247-258. PMID: 4773874

Sies, H. (1973). "Hydroperoxide metabolism in hemoglobin-free perfused rat liver." Hoppe Seylers Z Physiol Chem 354(8): 837. PMID: 4154889

Sies, H., T. Bucher, N. Oshino and B. Chance (1973). "Heme occupancy of catalase in hemoglobin-free perfused rat liver and of isolated rat liver catalase." Arch Biochem Biophys 154(1): 106-116. PMID: 4689773

Bucher, T., B. Brauser, A. Conze, F. Klein, O. Langguth and H. Sies (1972). "State of oxidation-reduction and state of binding in the cytosolic NADH-system as disclosed by equilibration with extracellular lactate-pyruvate in hemoglobin-free perfused rat liver." Eur J Biochem 27(2): 301-317. PMID: 4340564

Sies, H., S. T. Ta, B. Brauser and T. Bucher (1972). "Direct measurement of the state of the lactate dehydrogenase system in hemoglobin-free perfused rat liver." Adv Enzyme Regul 10: 309-322. PMID: 4653825

Sies, H. and G. Noack (1972). "Proton movement accompanying monocarboxylate permeation in hemoglobin-free perfused rat liver." FEBS Lett 22(2): 193-196. PMID: 11946594

Sies, H., C. Gerstenecker, H. Menzel and L. Flohe (1972). "Oxidation in the NADP system and release of GSSG from hemoglobin-free perfused rat liver during peroxidatic oxidation of glutathione by hydroperoxides." FEBS Lett 27(1): 171-175. PMID: 11946832

Sies, H., C. Gerstenecker, H. Menzel and L. Flohe (1972). "[Oxidation in glutathione and NADP system and GSSG liberation in extracellular spaces using hydroperoxide in the hemoglobin-free perfused rat liver]." Hoppe Seylers Z Physiol Chem 353(10): 1570. PMID: 4405475

Sies, H. (1971). "The state of NADPH-NADP + during mixed-function oxidation of hexobarbital in hemoglobin-free perfused rat liver." Chem Biol Interact 3(4): 308-309. PMID: 4399906

Sies, H. and M. Kandel (1970). "Positive increase of redox potential of the extramitochondrial NADP(H) system by mixed function oxidations in hemoglobin-free perfused rat liver." FEBS Lett 9(4): 205-208. PMID: 11947671

Sies, H. and B. Brauser (1970). "Interaction of mixed function oxidase with its substrates and associated redox transitions of cytochrome P-450 and pyridine nucleotides in perfused rat liver." Eur J Biochem 15(3): 531-540. PMID: 4393943

Sies, H. and B. Chance (1970). "The steady state level of catalase compound I in isolated hemoglobin-free perfused rat liver." FEBS Lett 11(3): 172-176. PMID: 11945479

Brauser, B., H. Sies and T. Bucher (1969). "Action of amobarbital on microsomal and mitochondrial respiratory state in perfused rat liver with and without phenobarbital induction." FEBS Lett 2(3): 170-172. PMID: 11946302

Brauser, B., H. Sies and T. Bucher (1969). "Reduction kinetics and content of cytochrome P-450 by application of dual wavelength techniques to hemoglobin-free perfused rat liver." FEBS Lett 2(3): 167-169. PMID: 11946301

Bucher, T. and H. Sies (1969). "Steady state relaxation of enolase in vitro and metabolic throughput in vivo of red and white rabbit muscles." Eur J Biochem 8(2): 273-283. PMID: 5781277

Sies, H., B. Brauser and T. Bucher (1969). "On the state of mitochondria in perfused liver: Action of sodium azide on respiratory carriers and respiration." FEBS Lett 5(5): 319-323. PMID: 11947307

Sies, H. and B. Brauser (1969). "[Redox status of the mitochondrial respiratory chain in the perfused rat liver]." Hoppe Seylers Z Physiol Chem 350(10): 1156. PMID: 5389286

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