Selected Publications

Jarius S, Ringelstein M, Haas J, Serysheva II, Komorowski L, Fechner K, Wandinger KP, Albrecht P, Hefter H, Moser A, Neuen-Jacob E, Hartung HP, Wildemann B, Aktas O. Inositol 1,4,5-trisphosphate receptor type 1 autoantibodies in paraneoplastic and non-paraneoplastic peripheral neuropathy. J Neuroinflammation. 2016 Oct 24;13(1):278. PubMed

Hartung B, Temme O, Neuen-Jacob E, Ritz-Timme S, Hinderhofer K, Daldrup T. Ornithine transcarbamylase deficiency of a male newborn with fatal outcome. Int J Legal Med. 2016 May;130(3):783-5. doi: 10.1007/s00414-015-1311-2. Epub 2016 Jan 11. PubMed

Semmler AL, Sacconi S, Bach J, Liebe C, Bürmann J, Kley RA, Ferbert A, Anderheiden R, Van den Bergh P, Martin JJ, De Jonghe P, Neuen-Jacob E, Müller O, Deschauer M, Bergmann M, Schröder J, Vorgerd M, Schulz JB, Weis J, Kress W, Claeys KG. Unusual multisystemic involvement and a novel BAG3 mutation revealed by NGS screening in a large cohort of myofibrillar myopathies. Orphanet J Rare Dis. 2014 Aug 1;9:121. doi: 10.1186/s13023-014-0121-9. PubMed

Schreckenbach T, Schröder JM, Voit T, Abicht A, Neuen-Jacob E, Roos A, Bulst S, Kuhl C, Schulz JB, Weis J, Claeys KG. (2014) Novel TPM3 mutation in a family with cap myopathy and review of the literature. Neuromuscul Disord. 2014 Feb;24(2):117-24. doi: 10.1016/j.nmd.2013.10.002. Epub 2013 Oct 23. PubMed

Stettner M, Albrecht P, Derksen A, Hartmann C, Turowski B, Neuen-Jacob E, Hartung HP, Kieseier BC, Arendt G. (2012) Clinical improvement precedes lesion size regression in a severe case of acute disseminated encephalomyelitis. BMJ Case Rep. 2012 Nov 21;2012. pii: bcr-2012-006844. doi: 10.1136/bcr-2012-006844. PubMed

Hartung B, Merk HF, Huckenbeck W, Daldrup T, Neuen-Jacob E, Ritz-Timme S. (2012) Severe generalised rhabdomyolysis with fatal outcome associated with isotretinoin. Int J Legal Med. 2012 Nov;126(6):953-6. doi: 10.1007/s00414-012-0750-2. Epub 2012 Aug 16. PubMed

C. Steidl, M.W. Baumgärtel, E. Neuen-Jacob, P. Berlit (2012) Vasculitic multiplex mononeuritis: Polyarteritis nodosa versus cryoglobulinemic vasculitis. Rheumatol Int. Aug;32(8):2543-6. doi: 10.1007/s00296-010-1447-9. Epub 2010 Apr 17. PubMed

Blum KS, Hagel C, Neuen-Jacob E, Herkenrath P, Fiehler J, Kohlschütter A, Lanfermann H, Ding XQ. (2012) Long-term diffusion impairment of cerebral white matter in a degenerative disease of the central and peripheral nervous system: reflection of chronic excitotoxicity? J Child Neurol. 2012 Feb;27(2):229-33. doi: 10.1177/0883073811419257. Epub 2011 Oct 3. PubMed

C. Scheller, G. Arendt, T. Nolting, C. Antke, S. Sopper, M. Maschke, M. Obermann, A. Angerer, I. W. Husstedt, F. Meisner, E. Neuen-Jacob, H. W. Müller, P. Carey, V. ter Meulen, P. Riederer, E. Koutsilieri (2010) Increased dopaminergic tone in therapy-naïve HIV-infected patients during asymptomatic infection is not associated with adaptive changes at the dopaminergic synapses. Journal of Neural Transmission, Volume 117, Issue 6, pp 699-705. Springer

Scheller C, Arendt G, Nolting T, Antke C, Sopper S, Maschke M, Obermann M, Angerer A, Husstedt IW, Meisner F, Neuen-Jacob E, Müller HW, Carey P, Ter Meulen V, Riederer P, Koutsilieri E. Increased dopaminergic neurotransmission in therapy-naïve asymptomatic HIV patients is not associated with adaptive changes at the dopaminergic synapses. J Neural Transm. 2010 Jun;117(6):699-705. doi: 10.1007/s00702-010-0415-6. Epub 2010 May 9. PubMed

Kiphuth IC, Neuen-Jacob E, Struffert T, Wehner M, Wallefeld W, Laing N, Schröder R. (2010) Myosin storage myopathy: a rare subtype of protein aggregate myopathies. Fortschr Neurol Psychiatr. 2010 Apr;78(4):219-22. doi: 10.1055/s-0029-1245145. Epub 2010 Apr 7. PubMed

Vordenbäumen S, Neuen-Jacob E, Richter J, Schneider M. (2010) Inclusion body myositis in a patient with long standing rheumatoid arthritis treated with anti-TNFalpha and rituximab. Clin Rheumatol. 2010 May;29(5):555-8. doi: 10.1007/s10067-009-1367-9. Epub 2010 Jan 27. PubMed

E. Neuen-Jacob (2009) Muskeldystrophien. In: J. Weis (Hrsg.) Sonderheft Muskelkrankheiten. Pathologe 30 (5):357-364. PubMed

E. Neuen-Jacob (2009) Neurotransmitter effects in Human immunodeficiency virus (HIV) and Simian immunodeficiency virus (SIV) infection. AIAAMC 8 (2): 153-163. Bentham Science

I.W. Husstedt, D. Reichelt, E. Neuen-Jacob, F. Kästner, R. von Einsiedel, B. Vielhaber, G. Arendt, S. Evers, K. Hahn (2009) Neurotoxicity and side-effects of highly active antiretroviral therapy (HAART) on the central and peripheral nerve system. AIAAMC 8 (2): 192-201. PubMed

I.W. Husstedt, D. Reichelt, E. Neuen-Jacob, K. Hahn, F. Kästner, R. von Einsiedel, B. Vielhaber, G. Arendt, S. Evers (2009) Highly active antiretroviral therapy of neuro-AIDS. Side effects on the nervous system and interactions. Nervenarzt 80 (10): 1133-4, 1136-8, 1140-2. PubMed

F. Otto, E. Neuen-Jacob, G. Arendt, O. Stüve, H.-P. Hartung (2009) A 69-year-old man with left hemispheric necrotizing mass lesion. Case of the month – March 2009. Brain Pathol 19 (3): 541-4. PubMed

F. Meisner, C. Scheller, S. Kneitz, S. Sopper, E. Neuen-Jacob, P. Riederer, V. ter Meulen, E. Koutsilieri for the German Competence Network HIV/AIDS (2008) Memantine up-regulates BDNF and prevents dopamine deficits in SIV-infected macaques: a novel pharmacological action of memantine. Neuropsychopharmacology 33 (9): 2228-36. Epub 2009 Oct. PubMed

F. Meisner, E. Neuen-Jacob, S. Sopper, M. Schmidt, S. Schlammes, C. Scheller, D. Vosswinkel, V. ter Meulen, P. Riederer, E. Koutsilieri for the German Competence Network HIV/AIDS (2008) Disruption of excitatory amino acid transporters in brains of SIV-infected rhesus macaques is associated with microglia activation. J Neurochem 104 (1): 202-9. Epub 2007 Nov 6. PubMed

Bajanowski T, Neuen-Jacob E, Schubries M, Zweihoff R (2008) Non-accidental head injury and shaken baby syndrome. Practical approach from selected case examples. Rechtsmedizin 18 (1): 23-8 Springer

Dybowski F, Neuen-Jacob E, Braun J (2008) Eosinophilic fasciitis and myositis: use of imaging modalities for diagnosis and monitoring. Ann Rheum Dis letter 67 (4): 572-4. PubMed

Kramer M, Baumgärtel MW, Neuen-Jacob E, Berlit P (2008) Myalgia in Neuro-Behçet's disease. Medication side effects or expression of underlying disease. Z Rheumatol 67 67(3):232-6. PubMed

Koy, B. Ilikovski, N. Laing, K. North, J. Weis, E. Neuen-Jacob, E. Mayatepek (2007) Nemaline Myopathy with exclusively intranuclear rods and a novel mutation in ACTA1 (Q139H). Neuropedatrics 39: 1-5. PubMed

C.P. Jacob, E. Koutsilieri J. Bartl, E. Neuen-Jacob, , T. Arzberger, N. Zander, R. Ravid, W. Roggendorf, P. Riederer, E. Grünblatt (2007) Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer’s disease. J Alzheimer’s Dis 11: 97-116. PubMed

B. Fink, M. Egl, J. Singer, M. Fürst, M. Bubenheim, E. Neuen-Jacob (2007) Morphologic changes in the vastus medialis muscle in patients with osteoarthritis of the knee. Arthritis and Rheumatism 56: 3626-3633. PubMed

G. Arendt, Th. Nolting, Ch. Frisch, I.W. Husstedt, N. Gregor, E. Koutsilieri, M. Maschke, A. Angerer, M. Obermann, E. Neuen-Jacob, O. Adams, S. Loeffert, P. Riederer, V. terMeulen, S. Sopper, and the German Competence Network HIV/AIDS (2007) Intrathecal viral replication and cerebral deficits in different stages of human immunodeficiency virus disease. J NeuroVirol 13: 225-232. PubMed

H. Köller, E. Neuen-Jacob, , A. Saleh, B.C. Kieseier, S. Jander, H.-P. Hartung (2006) Case report: A patient with a benign course of neuromyelitis optica (Devic`s syndrome) over 12 years: MRI follow up and histological findings. J Neurol 253 (6): 819-20. Epub 2006 Sep 26. PubMed

S. Sopper, C. Scheller, M. Jenuwein, C. Stahl-Hennig, E. Neuen-Jacob, E. Koutsilieri (2006) Early activation of microglia correlates with impairment in dopaminergic neurotransmission in SIV-infected macaques. J Med Primatology 35: 293. Wiley Online Library

R. Horvath, P. Schneiderat, B.G.H. Schoser, K. Gempel, E. Neuen-Jacob, H. Plöger, J. Müller-Höcker, D. Pongratz, A. Naini, S. DiMauro, H. Lochmüller (2006) Coenzyme Q10 defiency and isolated myopathy. Neurology 66: 253-255. PubMed

L. Burghaus, W. Liu, E. Neuen-Jacob, K. Gempel, W.F. Haupt (2006) Glycogenosis Type II (M. Pompe). Selective failure of the respiratory musculature - a rare first symptom. Nervenarzt 77 (2): 185-6. PubMed

S. Hoffjan, C. Thiels, M. Vorgerd, E. Neuen-Jacob, J.T. Epplen, W. Kress (2006) Extreme phenotypic variability in a German family with X-linked myotubular myopathy associated with E404K mutation in MTM1. Neuromuscul Disord 16 (11): 749-53. PubMed

Scheller C, Sopper S, Jenuwein M, Neuen-Jacob E, Tatschner T, Grunblatt E, Ter Meulen V, Riederer P, Koutsilieri E (2005) Early impairment in dopaminergic neurotransmission in brains of SIV-infected rhesus monkeys due to microglia activation. J Neurochem 95 (2): 377-87. Epub 2005 Aug 31. PubMed

C. Saft, J. Andrich, E. Neuen-Jacob, G. Schmid, L. Schols, G. Amoiridis (2004) Supracubital perineurioma misdiagnosed as carpal tunnel syndrome: case report. BMC Neurology 4:19. PubMed

M. Jenuwein, C. Scheller, E. Neuen-Jacob, S. Sopper, T. Taschner, V. ter Meulen, P. Riederer, E. Koutsilieri (2004) Dopamine deficits and regulation of the cAMP second messenger system in brains of SIV-infected rhesus monkeys. J Neurovirol 10: 163-70. PubMed

J. Nickel, E. Neuen-Jacob, A. Saleh, N. Gattermann, H.-P. Hartung, H. Köller (2004) CIDP and isolated ostesclerotic myeloma. Neuroimage. Neurology 63: 2439. PubMed

K. Hahn, G. Arendt, J.S. Braun, H.J. von Giesen, I.W. Husstedt, M. Maschke, E. Schielke (2004) for the German Neuro-AIDS working group: A placebo-controlled trial of Gabapentin for painful HIV-associated sensory neuropathies. J Neurol 251: 1260-1266. PubMed

B.C. Kieseier, H. Pischel, E. Neuen-Jacob, W.W. Tourtellotte, H.-P. Hartung (2003) ADAM-10 and ADAM-17 in the inflamed Human CNS. Glia 42: 387-405. PubMed

J.G. Richter, A. Becker, B. Ostendorf, C. Specker, G. Stoll, E. Neuen-Jacob, M. Schneider (2003) Differential diagnosis of high serum creatine kinase levels in systemic lupus erythematodes. Rheumatol Int 23: 319-323. PubMed

H. Köller, J. Kornischka, E. Neuen-Jacob, A. Saleh, H.-G. von Giesen, J. Schmiedel, H. Reichmann, H.-P. Hartung (2003) Persistent organic personalitiy change as rare psychiatric manifestation of MELAS syndrome. J. Neurol 250: 1501-2. PubMed

S. Jander, S. Bussini, E. Neuen-Jacob, F. Bosse, T. Menge, H.-W. Müller, G. Stoll (2002) Osteopontin: a novel axon-regulated Schwann cell gene. J Neurosci Res 67: 156-66. PubMed

Deutsche Neuro-Aids-Arbeitsgemeinschaft (DNAA) (2002) Aktuelle Diagnostik und Therapie opportunistischer Hirnerkrankungen bei AIDS. DMW 127: 1479-1485. Thieme

B. Fink, E. Neuen-Jacob, A. Lienert, A. Francke, O. Niggemeyer, W. Rüther (2001) Changes in canine skeletal muscles during experimental tibial lenghthening. Clin Orthoped Rel Res 385: 207-218. PubMed

G. Horneff, I. Paetzke, E. Neuen-Jacob (2001) Glycogenosis type V (McArdle’s disease) mimicking atypical myositis. Clin Rheumatol 20: 57-60. PubMed

T. Voit, P. Kutz, B. Leube, E. Neuen-Jacob, J.M. Schröder, D. Cavallotti, M.L. Vaccario, J. Schaper, P. Broich, R. Cohn, M. Baethmann, G. Göhlich-Ratmann, C. Scoppetta, R. Hermann (2001) Autosomal dominant distal myopathy: further evidence of a chromosome 14 locus. Neuromuscular disorders 11: 11-19. PubMed

B. Bachmann, M. Streppel, E. Neuen-Jacob (2001) Cricopharyngeal muscle hypertrophy associated with florid myositis. Dysphagia 16 (4): 244-8. PubMed

H.H. Goebel, L.E. Halbig, L. Goldfarb, R. Schober, M. Albani, E. Neuen-Jacob, T. Voit (2001) Reducing body myopathy with cytoplasmic bodies and rigid spine syndrome: a mixed congenital myopathy. Neuropediatrics 32: 196-205 PubMed

H.H. Goebel, E. Kominami, E. Neuen-Jacob, R.B. Wheeler (2001) Morphological studies on CLN2. Eur J Paed Neurol 5: 203-207 PubMed

M. Sabel, E. Neuen-Jacob, C. Vogt, F. Weber (2001) Intracerebral neurocysticercosis mimicking glioblastoma multiforme: a rare differential diagnosis in Central Europe. Neuroradiology 43 (3): 227-30 PubMed

F.W. Floeth, N. Shand, H. Bojar, H.B. Prisack, J. Felsberg, E. Neuen-Jacob, A. Aulich, K.J. Buger, W.J. Bock, F. Weber (2001) Local inflammation and devascularization – in vivo mechanisms of the “bystander effect” in VPC-mediated HSV-Tk/GCV gene therapy for human malignant glioma. Cancer Gene Therapy 8: 843-851 PubMed

M. Sabel, J. Felsberg, E. Neuen-Jacob, A. Lichota, A. Schnitzler, J. Herdmann (2000) Enlargement of a chronic aseptic lumbar epidural abscess by intraspinal injections – a rare cause of progressive paraparesis. Zentralbl Neurochir 61: 111-114 PubMed

J. Boström, G. Janssen, M. Messing-Jünger, E. Neuen-Jacob, V. Engelbrecht, H.G. Lenard, W.J. Bock, G. Reifenberger (2000) Multiple intracranial juvenile xanthogranulomas. J Neurosurg 93: 335-41. Review. PubMed

Hermann R, Straub V, Blank M, Kutzick C, Franke N, Neuen-Jacob E, Lenard HG, Kroger S, Voit T (2000) Dissociation of the Dystroglykan complex in caveolin-3-deficient limb girdle muscular dystrophy. Hum Mol Genet 9: 2335-2340 PubMed

W.F. Haupt, R. Firsching, H.C. Hansen, M. Horn, R.W.C. Janzen, E. Neuen-Jacob, H.W. Prange, J. Rudolf, S. Zschocke (2000) Das akute postanoxische Koma: Klinische, elektrophysiologische, biochemische und bildgebende Befunde. Intensivmedizin und Notfallmedizin, Volume 37, Issue 7, pp 597-607 Springer

Buchbeiträge und Monographien

E. Neuen-Jacob (1997) Das Spektrum der neuropathologischen Hirnveränderungen bei AIDS. Autopsiestudie mit neuen Krankheitsformen. Monografie, 160 Seiten. Europäischer Verlag der Wissenschaften Peter Lang, Frankfurt/Main. Zugl. Habilitationsschrift der Heinrich-Heine-Universität Düsseldorf.

E. Neuen-Jacob (2006) Kapital 8: Neuropathologische Diagnostik. In: P. Berlit (Hrsg.) Klinische Neurologie. Springer-Verlag Heidelberg, 2. Auflage, S. 199-227. Springer

E. Koutsilieri, G. Arendt, E. Neuen-Jacob, C. Scheller, E. Grünblatt, P. Riederer (2007) HIV-dementia: a neurodegenerative disorder with viral etiology. In Youdim M BH, Riederer P, Mandel SA, Battistin L (Hrsg.) Handbook of Neurochemistry and Molecular Neurobiology, 3rd edition, Degenerative Diseases of the Nervous System. Vol. 17, Springer Verlag Berlin Heidelberg 2007, S. 359-371. Springer