Publikationen 2014

Lange M, Fiedler M, Bankwitz D, Osburn W, Viazov S, Brovko O, Zekri AR, Khudyakov Y, Nassal M, Pumpens P, Pietschmann T, Timm J, Roggendorf M, Walker A. Hepatitis C virus hypervariable region 1 variants presented on hepatitis B virus capsid-like particles induce cross-neutralizing antibodies. PLoS One. 2014 Jul 11;9(7):e102235.

Ziegler S, Skibbe K, Walker A, Ke X, Heinemann FM, Heinold A, Mok JY, van Esch WJ, Yang D, Wölfl M, Timm J. Impact of sequence variation in a dominant HLA-A*02-restricted epitope in hepatitis C virus on priming and cross-reactivity of CD8+ T cells. J Virol. 2014 Oct;88(19):11080-90.

Thoens C, Berger C, Trippler M, Siemann H, Lutterbeck M, Broering R, Schlaak J, Heinemann FM, Heinold A, Nattermann J, Scherbaum N, Alter G, Timm J. KIR2DL3+NKG2A- natural killer cells are associated with protection from productive hepatitis C virus infection in people who inject drugs. J Hepatol. 2014 Sep;61(3):475-81.

Lipskoch M, Wiese M, Timm J, Roggendorf M, Viazov S. Genetic heterogeneity of hepatitis C virus cell entry receptors seems to have no influence on selection of virus variants. Virol J. 2014 Mar 14;11:50.

Nitschke K, Barriga A, Schmidt J, Timm J, Viazov S, Kuntzen T, Kim AY, Lauer GM, Allen TM, Gaudieri S, Rauch A, Lange CM, Sarrazin C, Eiermann T, Sidney J, Sette A, Thimme R, López D, Neumann-Haefelin C. HLA-B*27 subtype specificity determines targeting and viral evolution of a hepatitis C virus-specific CD8+ T cell epitope. J Hepatol. 2014 Jan;60(1):22-9.

Guberina H, Witzke O, Timm J, Dittmer U, Müller MA, Drosten C, Bonin F. A patient with severe respiratory failure caused by novel human coronavirus. Infection. 2014;42(1):203-6.

Graef P, Buchholz VR, Stemberger C, Flossdorf M, Henkel L, Schiemann M, Drexler I, Höfer T, Riddell SR, Busch DH. Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells. Immunity. 2014 Jul 17;41(1):116-26.

Roth S, Rottach A, Lotz-Havla AS, Laux V, Muschaweckh A, Gersting SW, Muntau AC, Hopfner KP, Jin L, Vanness K, Petrini JH, Drexler I, Leonhardt H, Ruland J. Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production. Nat Immunol. 2014 Jun;15(6):538-45.

Dai P, Wang W, Cao H, Avogadri F, Dai L, Drexler I, Joyce JA, Li XD, Chen Z, Merghoub T, Shuman S, Deng L. Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway. PLoS Pathog. 2014 Apr 17;10(4):e1003989.

Rothhammer V, Muschaweckh A, Gasteiger G, Petermann F, Heink S, Busch DH, Heikenwälder M, Hemmer B, Drexler I, Korn T. α4-integrins control viral meningoencephalitis through differential recruitment of T helper cell subsets. Acta Neuropathol Commun. 2014 Mar 7;2:27.

Becker PD, Nörder M, Weissmann S, Ljapoci R, Erfle V, Drexler I, Guzmán CA. Gene Expression Driven by a Strong Viral Promoter in MVA Increases Vaccination Efficiency by Enhancing Antibody Responses and Unmasking CD8? T Cell Epitopes. Vaccines (Basel). 2014 Jul 22;2(3):581-600.

Widera M, Hillebrand F, Erkelenz S, Vasudevan AA, Münk C, Schaal H. A functional conserved intronic G run in HIV-1 intron 3 is critical to counteract APOBEC3G-mediated host restriction. Retrovirology. 2014 Aug 29;11:72

Erkelenz S, Theiss S, Otte M, Widera M, Peter JO, Schaal H. Genomic HEXploring allows landscaping of novel potential splicing regulatory elements. Nucleic Acids Res. 2014; 42(16):10681-97.

Hillebrand F, Erkelenz S, Diehl N, Widera M, Noffke J, Avota E, Schneider-Schaulies S, Dabauvalle MC*, Schaal H*. The PI3K pathway acting on alternative HIV-1 pre-mRNA splicing. J Gen Virol. 2014 Aug;95(Pt 8):1809-15. *joint corresponding author

Tigges J, Krutmann J, Fritsche E, Haendeler J, Schaal H, Fischer JW, Kalfalah F, Reinke H, Reifenberger G, Stühler K, Ventura N, Gundermann S, Boukamp P, Boege F. The hallmarks of fibroblast ageing. Mech Ageing Dev. 2014 Jun;138:26-44.

Widera M, Klein AN, Cinar Y, Funke SA, Willbold D*, Schaal H*. The D-amino acid peptide D3 reduces amyloid fibril boosted HIV-1 infectivity. AIDS Res Ther. 2014 Jan 14;11(1):1. *joint corresponding author

Jost NH, Abel S, Hutzler M, Sparwasser T, Zimmermann A, Roers A, Müller W, Klopfleisch R, Hengel H, Westendorf AM, Buer J, Hansen W. Regulatory T cells and T-cell-derived IL-10 interfere with effective anti-cytomegalovirus immune response. Immunol Cell Biol. 2014 Nov;92(10):860-71.

Corrales-Aguilar E, Trilling M, Hunold K, Fiedler M, Le VT, Reinhard H, Ehrhardt K, Mercé-Maldonado E, Aliyev E, Zimmermann A, Johnson DC, Hengel H. Human cytomegalovirus Fcγ binding proteins gp34 and gp68 antagonize Fcγ receptors I, II and III.PLoS Pathog. 2014 May 15;10(5):e1004131.

Meisel R, Heseler K, Nau J, Schmidt SK, Leineweber M, Pudelko S, Wenning J, Zimmermann A, Hengel H, Sinzger C, Degistirici Ö, Sorg RV, Däubener W. Cytomegalovirus infection impairs immunosuppressive and antimicrobial effector functions of human multipotent mesenchymal stromal cells. Mediators Inflamm. 2014;2014:898630.

Nachmani D, Zimmermann A, Oiknine Djian E, Weisblum Y, Livneh Y, Khanh Le VT, Galun E, Horejsi V, Isakov O, Shomron N, Wolf DG, Hengel H, Mandelboim O. MicroRNA editing facilitates immune elimination of HCMV infected cells. PLoS Pathog. 2014 Feb 27;10(2):e1003963.

Zimmermann A*, Hauka S, Maywald M, Le VT, Schmidt SK, Däubener W, Hengel H. Checks and balances between human cytomegalovirus replication and indoleamine-2,3-dioxygenase. J Gen Virol. 2014 Mar;95(Pt 3):659-70. *corresponding author

Pei R, Grund S, Verheyen J, Esser S, Chen X, Lu M. Spontaneous reactivation of hepatitis B virus replication in an HIV coinfected patient with isolated anti-Hepatitis B core antibodies. Virol J. 2014 Jan 21;11:9.

Warnke C, Adams O, Kieseier B. Relevance of CD34+ cells as a reservoir for JC virus in patients with multiple sclerosis. JAMA Neurol. 2014 Sep;71(9):1192.

Warnke C, von Geldern G, Markwerth P, Dehmel T, Hoepner R, Gold R, Pawlita M, Kümpfel T, Mäurer M, Stangel M, Wegner F, Hohlfeld R, Straeten V, Limmroth V, Weber T, Hermsen D, Kleinschnitz C, Hartung HP, Wattjes MP, Svenningson A, Major E, Olsson T, Kieseier BC, Adams O. Cerebrospinal fluid JC virus antibody index for diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy. Ann Neurol. 2014 Dec;76(6):792-801.

Hoepner R, Ahlbrecht J, Faissner S, Schneider R, Dahlhaus S, Adams O, Raab P, Lukas C, Chan A, Stangel M, Gold R. Clinical and paraclinical findings in natalizumab-associated infratentorial progressive multifocal leukoencephalopathy patients. J Neurol Neurosurg Psychiatry. 2014 Oct;85(10):1177-8.

Ghosh S, Schuster FR, Adams O, Babor F, Borkhardt A, Comoli P, Handgretinger R, Lang P, Laws HJ, Siepermann M, Meisel R. Haploidentical stem cell transplantation in DOCK8 deficiency - Successful control of pre-existing severe viremia with a TCRaß/CD19-depleted graft and antiviral treatment. Clin Immunol. 2014 May-Jun;152(1-2):111-4.

Schmitt C, Raggub L, Linnenweber-Held S, Adams O, Schwarz A, Heim A. Donor origin of BKV replication after kidney transplantation. J Clin Virol. 2014 Feb;59(2):120-5.

Asang C, Laws HJ, Adams O, Enczmann J, Feiterna-Sperling C, Notheis G, Buchholz B, Borkhardt A, Neubert J. HIV-1 seroreversion in HIV-1-infected children: do genetic determinants play a role? AIDS. 2014 Feb 20;28(4):543-7.

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