Formation of the autoimmune T-cell response in type-1 diabetes

Effector T-cells have a relevant meaning for the development of an autoimmunereaction in type 1 diabetes. In the context of the following projects, the T-cell response in dependency on IL-7 in children with different stages of type 1 diabetes will be examine in more detail.

i) The role of IL-7 and IL-7/IL-2 receptor isoforms in the development of autoimmune T-cells in children with type-1 diabetes