Development of a functional bioink for 3D bioprinting of a vascularized in-vitro model of the lacrimal gland
In Europe, around 15–40% of the population is affected by the so-called "dry eye" condition. Some of them suffer from a specific form of this disease, which can cause severe pain, visual impairment, and even blindness. In many cases, these patients have a damaged lacrimal gland, triggered by radiation therapy for head tumors, injuries, or autoimmune diseases. Currently, there is no established therapy to fully restore the lacrimal gland. The goal of this project is to develop a three-dimensional lacrimal gland model to study disease mechanisms and potential therapies. To create this model, a specialized bioink for 3D bioprinting will be developed, designed to mimic the natural environment of lacrimal gland cells and support their functions, such as tear fluid production.
The project is funded by the Else Kröner-Fresenius-Stiftung. Click here for more information.
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