Originalpublikationen 2016


Bähr A., Singer A., Hain A., Vasudevan A.A., Schilling M., Reh J., Riess M., Panitz S., Serrano V., Schweizer M., König R., Chanda S., Häussinger D., Kochs G., Lindemann D. and Münk C. (2016)

Interferon but not MxB inhibits foamy retroviruses.

Virology 488, 51-6o (PubMed)

 

Dröge C., Schaal H., Engelmann G., Wenning D., Häussinger D. and Kubitz R. (2016)

Exon-skipping and mRNA decay in human liver tissue: molecular consequences of pathogenic bile salt export pump mutations.

Sci Rep 6, 24827 (PubMed)

 

Duhan V., Khairnar V., Friedrich S.K., Zhou F., Gassa A., Honke N., Shaabani N., Gailus N., Botezatu L., Khandanpour C., Dittmer U., Häussinger D., Recher M., Hardt C., Lang P.A. and Lang K.S. (2016)

Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8(+) T-cell priming and viral control.

Scientific Reports 6, 19191 (PubMed)

 

Ehlting C., Trilling M., Tiedje C., Le-Trilling V.T., Albrecht U., Kluge S., Zimmermann A., Graf D., Gaestel M., Hengel H., Häussinger D. and Bode J.G. (2016)

MAPKAP kinase 2 regulates IL-10 expression and prevents formation of intrahepatic myeloid cell aggregates during cytomegalovirus infections.

J Hepatol 64, 380-389 (PubMed)

 

Frieg B., Görg B., Homeyer N., Keitel V., Häussinger D. and Gohlke H. (2016)

Molecular Mechanisms of Glutamine Synthetase Mutations that Lead to Clinically Relevant Pathologies.

PLoS Comput Biol doi:10.1371/journal.pcbi.1004693 (PubMed)

 

Gassa A., Kalkavan H., Jian F., Duhan V., Khairnar V., Shaabani N., Honke N., Carpinteiro A., Botezatu L., Crivello P., Dolff S., Ferencik S., Häussinger D., Khandanpour C., Fleischhauer K., Witzke O., Wahlers T., Hardt C., Lang P.A. and Lang K.S. (2016)

High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine Model.

Cell Physiol Biochem 38, 1343-1353 (PubMed)

 

Ghallab A., Cellière G., Henkel S.G., Driesch D., Hoehme S., Hofmann U., Zellmer S., Godoy P., Sachinidis A., Blaszkewicz M., Reif R., Marchan R., Kuepfer L., Häussinger D., Drasdo D., Gebhardt R. and Hengstler J.G. (2016)

Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases.

J Hepatol doi: 0.1016/j.jhep.2015.11.018 (PubMed)

 

Honke N., Shaabani N., Merches K., Gassa A., Kraft A., Ehrhardt K., Häussinger D., Löhning M., Dittmer U., Hengel H., Recher M., Lang P.A. and Lang K.S. (2016)

Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN-I responses.

Eur J Immunol 46, 372-380 (PubMed)

 

Kubitz R., Dröge C., Kluge S., Stindt J., Stross C., Häussinger D., Flechtenmacher C., Wenning D., Teufel U., Schmitt C.P. and Engelmann G. (2016)

High affinity anti-BSEP antibodies after liver transplantation for PFIC-2 - Successful treatment with immunoadsorption and B-cell depletion.

Pediatr Transplant doi: 10.1111/petr.12751 (PubMed)

 

Lang E., Pozdeev V.I., Gatidis S., Qadri S.M., Häussinger D., Kubitz R., Herebian D., Mayatepek E., Lang F., Lang K.S. and Lang P.A. (2016)

Bile Acid-Induced Suicidal Erythrocyte.

Death Cell Physiol Biochem 38, 1500-9 (PubMed)

 

Marino D., Perković M., Hain A., Jaguva Vasudevan A.A., Hofmann H., Hanschmann K.M., Mühlebach M.D., Schumann G.G., König R., Cichutek K., Häussinger D. and Münk C. (2016)

APOBEC4 Enhances the Replication of HIV-1.

PLoS One 11, e0155422 (PubMed)

 

Nakhaei-Rad S., Nakhaeizadeh H., Götze S., Kordes C., Sawitza I., Hoffmann M.J., Franke M., Schulz W.A., Scheller J., Piekorz R.P., Häussinger D. and Ahmadian M.R. (2016)

The role of embryonic stem cell-expressed RAS (ERAS) in the maintenance of quiescent hepatic stellate cells.

J Biol Chem pii: jbc.M115.700088 (PubMed)

 

Oenarto J., Karababa A., Castoldi M., Bidmon H.J., Görg B. and Häussinger D. (2016)

Ammonia-induced miRNA expression changes in cultured rat astrocytes.

Scientific Reports 6, 18493 (PubMed)

 

Reich M., Deutschmann K., Sommerfeld A., Klindt C., Kluge S., Kubitz R., Ullmer C., Knoefel W.T., Herebian D., Mayatepek E., Häussinger D. and Keitel V. (2016)

TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro.

Gut 65, 487-501 (PubMed)

 

Schupp A.K., Trilling M., Rattay S., Le-Trilling V.T., Haselow K., Stindt J., Zimmermann A., Häussinger D., Hengel H. and Graf D.

Bile Acids Act as Soluble Host Restriction Factors Limiting Cytomegalovirus Replication in Hepatocytes.

J Virol pii: JVI.00299-16 (PubMed)

 

Shaabani N., Khairnar V., Duhan V., Zhou F., Tur R.F., Häussinger D., Recher M., Tumanov A.V., Hardt C., Pinschewer D., Christen U., Lang P.A., Honke N. and Lang K.S. (2016)

Two separate mechanisms of enforced viral replication balance innate and adaptive immune activation.

J Autoimmun 67, 82-89 (PubMed)

 

Sorg U.R., Behnke K., Degrandi D., Reich M., Keitel V., Herebian D., Deenen R., Beyer M., Schultze J.L., Köhrer K., Gabbert H.E., Mayatepek E., Häussinger D. and Pfeffer K. (2016)

Cooperative role of lymphotoxin β receptor and tumor necrosis factor receptor p55 in murine liver regeneration.

J Hepatol doi: 10.1016/j.jhep.2015.12.006 (PubMed)

 

Stindt J., Kluge S., Dröge C., Keitel V., Stross C., Baumann U., Brinkert F., Dhawan A., Engelmann G., Ganschow R., Gerner P., Grabhorn E., Knisely A.S., Noli K.A., Pukite I., Shepherd R.W., Ueno T., Schmitt L., Wiek C., Hanenberg H., Häussinger D. and Kubitz R. (2016)

Bile salt export pump-reactive antibodies form a polyclonal, multi-inhibitory response in antibody-induced bile salt export pump deficiency.

Hepatology 63, 524-537 (PubMed)

 

Stindt S., Cebula P., Albrecht U., Keitel V., Schulte Am Esch J., Knoefel W.T., Bartenschlager R., Häussinger D. and Bode J.G. (2016)

Hepatitis C Virus Activates a Neuregulin-Driven Circuit to Modify Surface Expression of Growth Factor Receptors of the ErbB Family.

PLoS One 11, e0148711 (PubMed)

 

Zhang Z., Gu Q., Jaguva Vasudevan A.A., Hain A., Kloke B.P., Hasheminasab S., Mulnaes D., Sato K., Cichutek K., Häussinger D., Bravo I.G., Smits S.H., Gohlke H. and Münk C. (2016)

Determinants of FIV and HIV Vif sensitivity of feline APOBEC3 restriction factors.

Retrovirology 13, 46 (PubMed)

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