Cécile and Oskar Vogt Institute of Brain Research
The brain is one of the most complex systems, and a fascinating subject of research. In the Cecile and Oskar Vogt Institute of Brain Research, we investigate the basic principles of organization and functions of the human brain, especially the cerebral cortex and its dependence on various internal and external influences.
We collaborate closely with the Research Centre Jülich (INM-1).
For our research, we draw on a wide range of methods, ranging from computer-based analysis of histological preparation, quantitative recepter autoradiography and molecular genetic analyzes to imaging. To study the architecture of connections in the human brain with unprecedented resolution in the micrometer range, we use the PLI (Polarized Light Imaging) method that was developed from researchers in our institute (the human connectome).
Further, we are working on the creation of an atlas of the human brain by using functional and architectural criteria, and provide the maps to the scientific community for free (JuBrain cytoviewer, SPM toolbox).
The three-dimensional model of the brain "BigBrain" makes it possible to understand the complex structure of the human brain at a microscopic level in all three directions (BigBrain).
Amunts, K., Lepage, C., Borgeat, L., Mohlberg, H., Dickscheid, T., Rousseau, M., Bludau, S., Bazin, P., Lewis, L., Oros-Peusquens, A., Shah, N., Lippert, T., Zilles, K., Evans, A., 2013. BigBrain - an ultra-high resolution 3D human brain model. Science Vol. 340 no. 6139 pp. 1472-1475
Together with the Research Centre Jülich, we are involved in the Human Brain Project, one of the two flagship projects of the FET initiative of the EU (http://www.humanbrainproject.eu).
Link to the brain collections