Study objective:

The aim of CorPuScula was to investigate acute health effects of fine and ultrafine particles in children and elderly adults living in Munich. The study was conducted by a team of researchers from the LMU Munich, funded by the Bavarian State. The group in Düsseldorf received the collected data to conduct further multi-pollutant analyses with a specific focus on independent effects of ultrafine particles.

Specific objectives

• To conduct a panel study in elementary school children and seniors living in a residential home
• To estimate acute health effects on pulmonary, cardiovascular and hematologic outcomes from short-term exposure to fine and ultrafine particles
• To investigate the independence of ultrafine particle effects from larger particles and ambient NO2 concentrations

Study design:

Panel study

Study population:

52 adults and 50 elementary school children in Munich

Study period:

2000 – 2002

Project Team Heinrich-Heine-University of Düsseldorf

• Pascale Haddad Thoelke
• Sarah Lucht
• Lina Glaubitz
• Katherine Orgurtsova

Collaborators

• CorPuScula-Team at LMU Munich

Project Publications

• Haddad P, Ogurtsova K, Lucht S, Glaubitz L, Höppe P, Nowak D, Angerer P, Hoffmann B. Short-term exposure to ultrafine and fine particulate matter with multipollutant modelling on heart rate variability among seniors and children from the CorPuScula (coronary, pulmonary, sanguis) longitudinal study in Germany. Frontiers in Epidemiology 2023 Nov 8:3:1278506. DOI: 10.3389/fepid.2023.1278506.

Related Publications

• Hoffmann B und Ogurtsova K. Adding Pieces to the Puzzle: Ultrafine Particles and Lung Cancer. American Journal of Respiratory and Critical Care Medicine 2024 Feb 1;209(3):241-242. DOI: 10.1164/rccm.202311-2098ED.