Institut für Pathologie - Publikationen 2008

Shibata T, Noguchi T, Takeno S, Gabbert HE, Ramp U, Kawahara K.
Disturbed XIAP and XAF1 expression balance is an independent prognostic factor in gastric adenocarcinomas
Ann Surg Oncol. 2008 Dec;15(12):3579-87. doi: 10.1245/s10434-008-0062-4. Epub 2008 Sep 19.
Topp SA, Krieg A, Koch A, Tidden CM, Ramp U, Hohlfeld T, Macher A, Schulte am Esch J 2nd, Eisenberger CF, Stoecklein NH, Knoefel WT.
Hemoglobin-glutamer 200 reduces reperfusion injury of the cold preserved rat liver by induction of heme oxygenase-1
J Surg Res. 2008 Dec;150(2):243-54. doi: 10.1016/j.jss.2008.02.033. Epub 2008 Mar 18.
Schneider PM, Metzger R, Schaefer H, Baumgarten F, Vallbohmer D, Brabender J, Wolfgarten E, Bollschweiler E, Baldus SE, Dienes HP, Hoelscher AH.
Response evaluation by endoscopy, rebiopsy, and endoscopic ultrasound does not accurately predict histopathologic regression after neoadjuvant chemoradiation for esophageal cancer
Ann Surg. 2008 Dec;248(6):902-8. doi: 10.1097/SLA.0b013e31818f3afb
Rohrbeck A, Neukirchen J, Rosskopf M, Pardillos GG, Geddert H, Schwalen A, Gabbert HE, von Haeseler A, Pitschke G, Schott M, Kronenwett R, Haas R, Rohr UP.
Gene expression profiling for molecular distinction and characterization of laser captured primary lung cancers
J Transl Med. 2008 Nov 7;6:69. doi: 10.1186/1479-5876-6-69.
Vallböhmer D, Marcus HE, Baldus SE, Brabender J, Drebber U, Metzger R, Hölscher AH, Schneider PM.
Serosal penetration is an important prognostic factor for gastrointestinal stromal tumors
Oncol Rep. 2008 Oct;20(4):779-83.
Burchardt M, Engers R, Müller M, Burchardt T, Willers R, Epstein JI, Ackermann R, Gabbert HE, de la Taille A, Rubin MA.
Interobserver reproducibility of Gleason grading: evaluation using prostate cancer tissue microarrays
J Cancer Res Clin Oncol. 2008 Oct;134(10):1071-8. doi: 10.1007/s00432-008-0388-0.
Epub 2008 Apr 8.
Hoffmann AC, Mori R, Vallbohmer D, Brabender J, Drebber U, Baldus SE, Klein E, Azuma M, Metzger R, Hoffmann C, Hoelscher AH, Danenberg KD, Prenzel KL, Danenberg PV.
High expression of heparanase is significantly associated with dedifferentiation and lymph node metastasis in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA and via HIF1a to HB-EGF and bFGF
J Gastrointest Surg. 2008 Oct;12(10):1674-81; discussion 1681-2.
doi: 10.1007/s11605-008-0628-2. Epub 2008 Aug 13.
Schumacher V, Gueler B, Looijenga LH, Becker JU, Amann K, Engers R, Dotsch J, Stoop H, Schulz W, Royer-Pokora B.
Characteristics of testicular dysgenesis syndrome and decreased expression of SRY and SOX9 in Frasier syndrome
Mol Reprod Dev. 2008 Sep;75(9):1484-94. doi: 10.1002/mrd.20889.
Warnecke-Eberz U, Bollschweiler E, Drebber U, Pohl A, Baldus SE, Hoelscher AH, Metzger R.
Frequent down-regulation of pim-1 mRNA expression in non-small cell lung cancer is associated with lymph node metastases
Oncol Rep. 2008 Sep;20(3):619-24.
Ban J, Bennani-Baiti IM, Kauer M, Schaefer KL, Poremba C, Jug G, Schwentner R, Smrzka O, Muehlbacher K, Aryee DN, Kovar H.
EWS-FLI1 suppresses NOTCH-activated p53 in Ewing's sarcoma
Cancer Res. 2008 Sep 1;68(17):7100-9. doi: 10.1158/0008-5472.CAN-07-6145.
Paulussen M, Craft AW, Lewis I, Hackshaw A, Douglas C, Dunst J, Schuck A, Winkelmann W, Köhler G, Poremba C, Zoubek A, Ladenstein R, van den Berg H, Hunold A, Cassoni A, Spooner D, Grimer R, Whelan J, McTiernan A, Jürgens H; European Intergroup Cooperative Ewing's Sarcoma Study-92.
Results of the EICESS-92 Study: two randomized trials of Ewing's sarcoma treatment-cyclophosphamide compared with ifosfamide in standard-risk patients and assessment of benefit of etoposide added to standard treatment in high-risk patients
J Clin Oncol. 2008 Sep 20;26(27):4385-93. doi: 10.1200/JCO.2008.16.5720.
Gluz O, Wild P, Meiler R, Diallo-Danebrock R, Ting E, Mohrmann S, Schuett G, Dahl E, Fuchs T, Herr A, Gaumann A, Frick M, Poremba C, Nitz UA, Hartmann A.
Nuclear karyopherin alpha2 expression predicts poor survival in patients with advanced breast cancer irrespective of treatment intensity
Int J Cancer. 2008 Sep 15;123(6):1433-8. doi: 10.1002/ijc.23628.
Fleisch MC, Lux J, Schoppe M, Grieshaber K, Hampl M.
Placenta percreta leading to spontaneous complete uterine rupture in the second trimester. Example of a fatal complication of abnormal placentation following uterine scarring
Gynecol Obstet Invest. 2008;65(2):81-3. Epub 2007 Sep 13.
Martins AS, Ordoñez JL, García-Sánchez A, Herrero D, Sevillano V, Osuna D, Mackintosh C, Caballero G, Otero AP, Poremba C, Madoz-Gúrpide J, de Alava E.
A pivotal role for heat shock protein 90 in Ewing sarcoma resistance to anti-insulin-like growth factor 1 receptor treatment: in vitro and in vivo study
Cancer Res. 2008 Aug 1;68(15):6260-70. doi: 10.1158/0008-5472.CAN-07-3074.
Cupisti K, Ramp U, Raffel A, Krausch M, Rehders A, Knoefel WT.
Multiple giant scalp metastases of a follicular thyroid carcinoma
World J Surg Oncol. 2008 Aug 11;6:82. doi: 10.1186/1477-7819-6-82.
Alakus H, Grass G, Hennecken JK, Bollschweiler E, Schulte C, Drebber U, Baldus SE, Metzger R, Hölscher AH, Mönig SP.
Clinicopathological significance of MMP-2 and its specific inhibitor TIMP-2 in gastric cancer
Histol Histopathol. 2008 Aug;23(8):917-23.
Heikaus S, Kempf T, Mahotka C, Gabbert HE, Ramp U.
Caspase-8 and its inhibitors in RCCs in vivo: the prominent role of ARC
Apoptosis. 2008 Jul;13(7):938-49. doi: 10.1007/s10495-008-0225-6.
Krüppel U, Müller-Schiffmann A, Baldus SE, Smola-Hess S, Steger G.
E2 and the co-activator p300 can cooperate in activation of the human papillomavirus type 16 early promoter
Virology. 2008 Jul 20;377(1):151-9. doi: 10.1016/j.virol.2008.04.006. Epub 2008 May 21.
Hoffmann AC, Mori R, Vallbohmer D, Brabender J, Klein E, Drebber U, Baldus SE, Cooc J, Azuma M, Metzger R, Hoelscher AH, Danenberg KD, Prenzel KL, Danenberg PV.
High expression of HIF1a is a predictor of clinical outcome in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA, VEGF, and bFGF
Neoplasia. 2008 Jul;10(7):674-9.
Dietel M, Tannapfel A, Baretton G, Kreipe H, Kloor M, Gabbert H, Kirchner T.
Molecular pathologic KRAS mutation analysis. A prerequisite of effective antibody treatment for metastasized colorectal cancer
Chirurg. 2008 Jun;79(6):576-9. doi: 10.1007/s00104-008-1514-x.
Vallböhmer D, Kuhn E, Warnecke-Eberz U, Brabender J, Hoffmann AC, Metzger R, Baldus SE, Drebber U, Hoelscher AH, Schneider PM.
Failure in downregulation of intratumoral survivin expression following neoadjuvant chemoradiation in esophageal cancer
Pharmacogenomics. 2008 Jun;9(6):681-90. doi: 10.2217/14622416.9.6.681.
Drebber U, Baldus SE, Nolden B, Grass G, Bollschweiler E, Dienes HP, Hölscher AH,
Mönig SP.
The overexpression of c-met as a prognostic indicator for gastric carcinoma compared to p53 and p21 nuclear accumulation
Oncol Rep. 2008 Jun;19(6):1477-83.
Krieg A, Esch JS 2nd, Poll LW, Braunstein S, Knoefel WT.
Mucinous cystadenoma of the appendix misdiagnosed as cystic hydatid disease of the liver: a case report
J Med Case Rep. 2008 Jun 25;2:218. doi: 10.1186/1752-1947-2-218.
Heikaus S, Matuszek KS, Suschek CV, Ramp U, Reinecke P, Grinstein E, Haremza J, Gabbert HE, Mahotka C.
Paclitaxel (Taxol)-induced apoptosis in human epithelioid sarcoma cell lines is enhanced by upregulation of CD95 ligand (FasL/Apo-1L)
J Cancer Res Clin Oncol. 2008 Jun;134(6):689-95. Epub 2007 Dec 12.
Gripp S, Peiper M, Matuschek C, Giro C, Steinbach G, Hermsen D, van Griensven M, Budach W, Engers R, Gerber PA, Hefter H, Spiess B, Orth K, Bölke E.
Validity of S-100 B in patients after brain radiation
Eur J Med Res. 2008 Jun 24;13(6):299-303.
Gluz O, Nitz UA, Harbeck N, Ting E, Kates R, Herr A, Lindemann W, Jackisch C, Berdel WE, Kirchner H, Metzner B, Werner F, Schütt G, Frick M, Poremba C, Diallo-Danebrock R, Mohrmann S;
Triple-negative high-risk breast cancer derives particular benefit from dose intensification of adjuvant chemotherapy: results of WSG AM-01 trial
Ann Oncol. 2008 May;19(5):861-70. doi: 10.1093/annonc/mdm551. Epub 2008 Jan 3.
Hammerich KH, Hille S, Ayala GE, Wheeler TM, Engers R, Ackermann R, Mueller-Mattheis V.
Malignant advanced granulosa cell tumor of the adult testis:
case report and review of the literature

Hum Pathol. 2008 May;39(5):701-9. doi: 10.1016/j.humpath.2007.09.015. Epub 2008 Mar 4.
Pourhassan S, Duran M, Engers R, Sandmann W.
Do we have to remove a painless collar swelling along the carotid artery?
Laryngorhinootologie. 2008 May;87(5):341-4. Epub 2007 Oct 25.
Warnecke-Eberz U, Baldus SE, Bollschweiler E, Hoelscher AH, Metzger R.
Up-regulation of survivin mRNA might be a marker for non-invasive detection of non-small cell lung cancer rather than for prognosis
Anticancer Res. 2008 May-Jun;28(3A):1525-9.
Dietel M; Tannapfel A; Baretton G; Kreipe H; Kloor M; Gabbert H; Kichner T
Molecular pathologic analysis of the K-RAS mutation status of metastasised colorectal carcinoma. An example of predictive pathology
ONKOLOGE 2008 APR  14(4):405-408; DOI: 10.1007/s00761-008-1367-4
Kleff V, Sorg UR, Bury C, Suzuki T, Rattmann I, Jerabek-Willemsen M, Poremba C, Flasshove M, Opalka B, Trapnell B, Dirksen U, Moritz T.
Gene therapy of beta(c)-deficient pulmonary alveolar proteinosis (beta(c)-PAP): studies in a murine in vivo model
Mol Ther. 2008 Apr;16(4):757-64. doi: 10.1038/mt.2008.7. Epub 2008 Mar 4.
Matthaei H, Bölke E, Schmelzle M, Budach W, Orth K, Engers R, Cohnen M, Matuschek C, Gripp S, Knoefel WT, Peiper M.
Modern therapy of rectal carcinoma
Eur J Med Res. 2008 Apr 30;13(4):139-46.
Richter J, Lux J, Reinecke P, Müller-Mattheis V.
Of flukes and fistulae
Lancet. 2008 Apr 12;371(9620):1308. doi: 10.1016/S0140-6736(08)60566-8.
Schaefer KL, Eisenacher M, Braun Y, Brachwitz K, Wai DH, Dirksen U, Lanvers-Kaminsky C, Juergens H, Herrero D, Stegmaier S, Koscielniak E, Eggert A, Nathrath M, Gosheger G, Schneider DT, Bury C, Diallo-Danebrock R, Ottaviano L, Gabbert HE, Poremba C.
Microarray analysis of Ewing's sarcoma family of tumours reveals characteristic gene expression signatures associated with metastasis and resistance to chemotherapy
Eur J Cancer. 2008 Mar;44(5):699-709. doi: 10.1016/j.ejca.2008.01.020. Epub 2008 Feb 21.
Stelljes M, Hermann S, Albring J, Köhler G, Löffler M, Franzius C, Poremba C, Schlösser V, Volkmann S, Opitz C, Bremer C, Kucharzik T, Silling G, Schober O, Berdel WE, Schäfers M, Kienast J.
Clinical molecular imaging in intestinal graft-versus-host disease:
mapping of disease activity, prediction, and monitoring of treatment efficiency by positron emission tomography

Blood. 2008 Mar 1;111(5):2909-18. Epub 2007 Dec 5.
Warnecke-Eberz U, Prenzel KL, Baldus SE, Metzger R, Dienes HP, Bollschweiler E, Hoelscher AH, Schneider PM.
Significant down-regulation of the plasminogen activator inhibitor 1 mRNA in pancreatic cancer
Pancreas. 2008 Mar;36(2):173-7. doi: 10.1097/MPA.0b013e31815ac538.
Ott N, Geddert H, Sarbia M.
Polymorphisms in methionine synthase (A2756G) and cystathionine beta-synthase (844ins68) and susceptibility to carcinomas of the upper gastrointestinal tract
J Cancer Res Clin Oncol. 2008 Mar;134(3):405-10. Epub 2007 Aug 29.
Pomjanski N, Grote HJ, Sander O, Heikaus S, Müller KM, Böcking A.
Early cytological diagnosis of diffuse malignant mesothelioma of the peritoneum: a case report
Diagn Cytopathol. 2008 Feb;36(2):120-3. doi: 10.1002/dc.20759.
Scheckenbach K, Winterhalter S, Chaker A, Hoffmann TK, Ramp U, Wagenmann M.
MALT lymphoma of the orbit
HNO. 2008 Feb;56(2):161-4.
Vallböhmer D, Marcus HE, Baldus SE, Brabender J, Lurje G, Drebber U, Metzger R, Hölscher AH, Schneider PM.
Comparative analysis of four histopathological classification systems to discriminate benign and malignant behaviour in gastrointestinal stromal tumors
Anticancer Res. 2008 Jan-Feb;28(1B):367-72.
Von Stockmar-Von Wangenheim CA, Mönig SP, Schneider PM, Landsberg S, Drebber U, Hölscher AH, Dienes HP, Baldus SE.
p16, cyclin D1 and Rb expression in colorectal carcinomas: Correlations with clinico-pathological parameters and prognosis
Mol Med Rep. 2008 Jan-Feb;1(1):27-32.
Schmitt-Graeff AH, Teo SS, Olschewski M, Schaub F, Haxelmans S, Kirn A, Reinecke P, Germing U, Skoda RC.
JAK2V617F mutation status identifies subtypes of refractory anemia with ringed sideroblasts associated with marked thrombocytosis
Haematologica. 2008 Jan;93(1):34-40. doi: 10.3324/haematol.11581.
Heikaus S, van den Berg L, Kempf T, Mahotka C, Gabbert HE, Ramp U.
HA14-1 is able to reconstitute the impaired mitochondrial pathway of apoptosis in renal cell carcinoma cell lines
Cell Oncol. 2008;30(5):419-33.
Bölke E, Gerber PA, Peiper M, Engers R, Pape H.
Chloromas
Wien Klin Wochenschr. 2008;120(7-8):209. doi: 10.1007/s00508-008-0952-2.
Peiper M, Gerber PA, Engers R, Matuschek C, Budach W, Gripp S, Pape H, Orth K, Bölke E.
Soft tissue sarcoma
Wien Klin Wochenschr. 2008;120(23-24):732. doi: 10.1007/s00508-008-1111-5.
Pape H, Orth K, Engers R, Matuschek C, Müller A, Hartmann KA, Gerber PA, Lammering G, Habermehl D, Fenk R, Budach W, Gripp S, Peiper M, Bölke E.
Radiotherapy of soft tissue sarcoma--part of a multidisciplinary strategy
Wien Klin Wochenschr. 2008;120(23-24):723-31. doi: 10.1007/s00508-008-1115-1.

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