CIRCULATING TUMOR CELLS THERAPEUTIC APHERESIS (CTCTrap PROJECT) aimed to isolate and characterize all tumor cells circulating in blood to enable a real-time liquid biopsy for all cancer patients with metastatic disease regardless whether or not the disseminated disease has been clinically detected. The CTCTrap consortium consists of 4 Small & Medium Enterprises (SME) and 7 academic institutions and is funded through FP7 health.2012.1.2-1 #305341. (https://www.utwente.nl/en/tnw/ctctrap)