Welcome to the Institute of Biochemistry and Molecular Biology II
The Institute of Biochemistry and Molecular Biology II focuses on basic medical research in the field of immune regulation and on training students of human medicine and dentistry.
• The immune system not only plays a central role in defending against pathogens, but is also crucial for maintaining homeostasis, for example in energy metabolism. In addition, it influences aging processes and contributes significantly to cancer defense.
• A particular focus is on signal transduction, with a special interest in cytokines – the hormones of the immune system.
• Our goal is to better understand and specifically manipulate immunological processes, using synthetic biology methods.
• In our scientific work, we use various methods, including in vitro methods with DNA, proteins, protein design, and cell culture, as well as in vivo models with mice.
• In addition to supervising doctoral theses for natural scientists (Dr. rer. nat.), we also offer supervision for doctoral theses for medical doctors (Dr. med.). We are involved in the master's program “Molecular BioMedicine” and offer master's theses. https://www.medizinstudium.hhu.de and www.molekularebiomedizin.hhu.de
Research focus areas and research groups
- The role of cytokines in immune defense (Scheller research group)
- Cytokines of the IL-12 family (Floß research group)
- Synthetic immunology (Floß and Scheller research groups)
- Sirtuins in aging (Piekorz research group)