Publikationen 2021 - 2012

Publikationen Biomaterialbank - 2024
Lisa Zipper, Rabea Wagener, Ute Fischer, Anna Hoffmann, Layal Yasin, Danielle Brandes, Stavrieta Soura, Ammarah Anwar, Carolin Walter, Julian Varghese, Julia Hauer, Franziska Auer, Sanil Bhatia, Martin Dugas, Stefanie V Junk, Martin Stanulla, Oskar A Haas, Arndt Borkhardt, Tobias Reiff, Triantafyllia Brozou
Hyperdiploid acute lymphoblastic leukemia in children with LZTR1 germline variants
Hemasphere. 2024 Jan 26;8(1):e26. doi: 10.1002/hem3.26. eCollection 2024 Jan. 
Rabea Wagener, Danielle Brandes, Marie Jung, Maxim A Huetzen, Anke K Bergmann, Stephanie Panier, Daniel Picard, Ute Fischer, Ron D Jachimowicz, Arndt Borkhardt, Triantafyllia Brozou
Optical genome mapping identifies structural variants in potentially new cancer predisposition candidate genes in pediatric cancer patients
Int J Cancer. 2024 Feb 15;154(4):607-614. doi: 10.1002/ijc.34721. Epub 2023 Sep 30.
Maria Sirenko, Elsa Bernard, Maria Creignou, Dylan Domenico, Andrea Farina, Juan E Arango Ossa, Olivier Kosmider, Robert Hasserjian, Martin Jädersten, Ulrich Germing, Guillermo Sanz, Arjan A van de Loosdrecht, Carmelo Gurnari, Matilde Yung Follo, Felicitas Thol, Lurdes Zamora, Ronald Feitosa Pinheiro, Andrea Pellagatti, Harold K Elias, Detlef Haase, Birgitta Sander, Elisa Orna, Katharina Zoldan, Lea Naomi Eder, Wolfgang R Sperr, Renate Thalhammer, Christina Ganster, Lionel Adès, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Kety Huberman, Pierre Fenaux, Monika Belickova, Michael R Savona, Virginia M Klimek, Fabio P S Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Solé, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Seishi Ogawa, Michaela Fontenay, Joop H Jansen, Jose Cervera, Benjamin L Ebert, Rafael Bejar, Peter L Greenberg, Norbert Gattermann, Luca Malcovati, Mario Cazzola, David B Beck, Eva Hellström-Lindberg, Elli Papaemmanuil  
Molecular and clinical presentation of UBA1-mutated myelodysplastic syndromes 
Blood. 2024 Sep 12;144(11):1221-1229. doi: 10.1182/blood.2023023723.
Cristina Astrid Tentori, Caterina Gregorio, Marie Robin, Nico Gagelmann, Carmelo Gurnari, Somedeb Ball, Juan Carlos Caballero Berrocal, Luca Lanino, Saverio D'Amico, Marta Spreafico, Giulia Maggioni, Erica Travaglino, Elisabetta Sauta, Manja Meggendorfer, Lin-Pierre Zhao, Alessia Campagna; GenoMed4All, Synthema, GESMD, FISIM, and EuroBloodNET; Victor Savevski, Armando Santoro, Najla Al Ali, David Sallman, Francesc Sole, Guillermo Garcia-Manero, Ulrich Germing, Nicolaus Kroger, Shahram Kordasti, Valeria Santini, Guillermo Sanz, Wolfgang Kern, Uwe Platzbecker, Maria Diez-Campelo, Jaroslaw P Maciejewski, Lionel Ades, Pierre Fenaux, Torsten Haferlach, Amer M Zeidan, Gastone Castellani, Rami Komrokji, Francesca Ieva, Matteo Giovanni Della Porta
Clinical and Genomic-Based Decision Support System to Define the Optimal Timing of Allogeneic Hematopoietic Stem-Cell Transplantation in Patients With Myelodysplastic Syndromes
J Clin Oncol. 2024 Aug 20;42(24):2873-2886. doi: 10.1200/JCO.23.02175. Epub 2024 May 9.
Elsa Bernard, Robert P Hasserjian, Peter L Greenberg, Juan E Arango Ossa, Maria Creignou, Heinz Tuechler, Jesus Gutierrez-Abril, Dylan Domenico, Juan S Medina-Martinez, Max Levine, Konstantinos Liosis, Noushin Farnoud, Maria Sirenko, Martin Jädersten, Ulrich Germing, Guillermo Sanz, Arjan A van de Loosdrecht, Yasuhito Nannya, Olivier Kosmider, Matilde Y Follo, Felicitas Thol, Lurdes Zamora, Ronald F Pinheiro, Andrea Pellagatti, Harold K Elias, Detlef Haase, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Pierre Fenaux, Monika Belickova, Michael R Savona, Virginia M Klimek, Fabio P S Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francesc Solé, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Voso, Lee-Yung Shih, Michaela Fontenay, Joop H Jansen, José Cervera, Norbert Gattermann, Benjamin L Ebert, Rafael Bejar, Luca Malcovati, Seishi Ogawa, Mario Cazzola, Eva Hellström-Lindberg, Elli Papaemmanuil
Molecular taxonomy of myelodysplastic syndromes and its clinical implications
Blood. 2024 Oct 10;144(15):1617-1632. doi: 10.1182/blood.2023023727.
Maria Julia Montoro, Laura Palomo, Claudia Haferlach, Pamela Acha, Onyee Chan, Víctor Navarro, Yasuo Kubota, Felicitas Isabel Schulz, Manja Meggendorfer, Robert Briski, Najla Al Ali, Blanca Xicoy, Félix López-Cadenas, Francesc Bosch, Teresa González, Lea Naomi Eder, Andrés Jerez, Yu-Hung Wang, Alessia Campagna, Valeria Santini, Teresa Bernal Del Castillo, Esperanza Such, Hwei-Fang Tien, Nicolás Diaz Varela, Uwe Platzbecker, Detlef Haase, María Díez-Campelo, Matteo Della Porta, Guillermo Garcia-Manero, Daniel H Wiseman, Ulrich Germing, Jaroslaw P Maciejewski, Rami S Komrokji, Francesc Sole, Torsten Haferlach, David Valcárcel
Influence of TP53 gene mutations and their allelic status in myelodysplastic syndromes with isolated 5q deletion
Blood. 2024 Oct 17;144(16):1722-1731. doi: 10.1182/blood.2024023840.
Paolo Mazzeo, Christina Ganster, John Wiedenhöft, Katayoon Shirneshan, Katharina Rittscher, Elzbieta B Brzuszkiewicz, Doris Steinemann, Maximilian Schieck, Catharina Müller-Thomas, Hannes Treiber, Friederike Braulke, Ulrich Germing, Katja Sockel, Ekaterina Balaian, Julie Schanz, Uwe Platzbecker, Katharina S Götze, Detlef Haase
Comprehensive sequential genetic analysis delineating frequency, patterns, and prognostic impact of genomic dynamics in a real-world cohort of patients with lower-risk MDS
Hemasphere. 2024 Sep 23;8(9):e70014. doi: 10.1002/hem3.70014. eCollection 2024 Sep.
Rami S Komrokji, Luca Lanino, Somedeb Ball, Jan P Bewersdorf, Monia Marchetti, Giulia Maggioni, Erica Travaglino, Najla H Al Ali, Pierre Fenaux, Uwe Platzbecker, Valeria Santini, Maria Diez-Campelo, Avani Singh, Akriti G Jain, Luis E Aguirre, Sarah M Tinsley-Vance, Zaker I Schwabkey, Onyee Chan, Zhouer Xie, Andrew M Brunner, Andrew T Kuykendall, John M Bennett, Rena Buckstein, Rafael Bejar, Hetty E Carraway, Amy E DeZern, Elizabeth A Griffiths, Stephanie Halene, Robert P Hasserjian, Jeffrey Lancet, Alan F List, Sanam Loghavi, Olatoyosi Odenike, Eric Padron, Mrinal M Patnaik, Gail J Roboz, Maximilian Stahl, Mikkael A Sekeres, David P Steensma, Michael R Savona, Justin Taylor, Mina L Xu, Kendra Sweet, David A Sallman, Stephen D Nimer, Christopher S Hourigan, Andrew H Wei, Elisabetta Sauta, Saverio D'Amico, Gianluca Asti, Gastone Castellani, Mattia Delleani, Alessia Campagna, Uma M Borate, Guillermo Sanz, Fabio Efficace, Steven D Gore, Tae Kon Kim, Navel Daver, Guillermo Garcia-Manero, Maria Rozman, Alberto Orfao, Sa A Wang, M Kathryn Foucar, Ulrich Germing, Torsten Haferlach, Phillip Scheinberg, Yasushi Miyazaki, Marcelo Iastrebner, Austin Kulasekararaj, Thomas Cluzeau, Shahram Kordasti, Arjan A van de Loosdrecht, Lionel Ades, Amer M Zeidan, Matteo G Della Porta; International Consortium on Myelodysplastic Syndromes
Data-driven, harmonised classification system for myelodysplastic syndromes: a consensus paper from the International Consortium for Myelodysplastic Syndromes
Lancet Haematol. 2024 Nov;11(11):e862-e872. doi: 10.1016/S2352-3026(24)00251-5. Epub 2024 Oct 9.
Pailin Pongratanakul, Felix Bremmer, Stella Pauls, Gereon Poschmann, Catena Kresbach, Fatma Parmaksiz, Margaretha A Skowron, Janina Fuß, Alexa Stephan, Pia Paffenholz, Kai Stühler, Ulrich Schüller, Philipp Ströbel, Axel Heidenreich, Yue Che, Peter Albers, Daniel Nettersheim
Assessing the risk to develop a growing teratoma syndrome based on molecular and epigenetic subtyping as well as novel secreted biomarkers
Cancer Lett. 2024 Mar 31:585:216673. doi: 10.1016/j.canlet.2024.216673. Epub 2024 Jan 29.
Publikationen Biomaterialbank - 2023
Felix Bremmer, Pailin Pongratanakul, Margaretha Skowron, Yue Che, Annika Richter, Stefan Küffer, Kirsten Reuter-Jessen, Hanibal Bohnenberger, Stella Pauls, Catena Kresbach, Ulrich Schüller, Kai Stühler, Philipp Ströbel, Peter Albers, Daniel Nettersheim
Characterizing the mutational burden, DNA methylation landscape, and proteome of germ cell tumor-related somatic-type malignancies to identify the tissue-of-origin, mechanisms of therapy resistance, and druggable Targets
Br J Cancer. 2023 Nov;129(10):1580-1589. doi: 10.1038/s41416-023-02425-5. Epub 2023 Sep 19.
Publikationen Biomaterialbank - 2021 
Lena Haeberle, Martin Schramm, Wolfgang Goering, Lisa Frohn, Caroline Driescher, Werner Hartwig, Hubert-Karl Preissinger-Heinzel, Torsten Beyna, Horst Neuhaus, Katharina Fuchs, Verena Keitel-Anselmino, Wolfram Trudo Knoefel, Irene Esposito
Molecular analysis of cyst fluids improves the diagnostic accuracy of pre-operative assessment of pancreatic cystic lesions
Sci Rep. 2021 Feb 3;11(1):2901. doi: 10.1038/s41598-021-81065-2.
Rabea Wagener, Julia Täubner, Carolin Walter, Layal Yasin, Deya Alzoubi, Christoph Bartenhagen, Andishe Attarbaschi, Carl-Friedrich Classen, Udo Kontny, Julia Hauer, Ute Fischer, Martin Dugas, Michaela Kuhlen, Arndt Borkhardt, Triantafyllia Brozou
Comprehensive germline-genomic and clinical profiling in 160 unselected children and adolescents with cancer
Eur J Hum Genet. 2021 Aug;29(8):1301-1311. doi: 10.1038/s41431-021-00878-x. Epub 2021 Apr 12. PMID:33840814
Elbracht M, Meyer R, Kricheldorf K, Gezer D, Thomas E, Betz B, Kurth I, Teichmann LL, Brümmendorf TH, Germing U, Isfort S, Koschmieder S.
Germline variants in DNA repair genes, including BRCA1/2, may cause familial myeloproliferative neoplasms
Blood Adv. 2021 Sep 14;5(17):3373-3376. doi: 10.1182/bloodadvances.2021004811.
Hecht A, Meyer JA, Jann JC, Sockel K, Giagounidis A, Götze KS, Letsch A, Haase D, Schlenk RF, Haferlach T, Schafhausen P, Bug G, Lübbert M, Thol F, Büsche G, Schuler E, Nowak V, Obländer J, Fey S, Müller N, Metzgeroth G, Hofmann WK, Germing U, Nolte F, Reinwald M, Nowak D. Ann
Genome-wide DNA methylation analysis pre- and post-lenalidomide treatment in patients with myelodysplastic syndrome with isolated deletion (5q)
Hematol. 2021 Jun;100(6):1463-1471. doi: 10.1007/s00277-021-04492-1. Epub 2021 Apr 27.
Publikationen Biomaterialbank - 2020
Caroline Driescher, Katharina Fuchs, Lena Haeberle, Wolfgang Goering, Lisa Frohn, Friederike V Opitz, Dieter Haeussinger, Wolfram Trudo Knoefel, Verena Keitel, Irene Esposito
Bile-Based Cell-Free DNA Analysis Is a Reliable Diagnostic Tool in Pancreatobiliary Cancer
Cancers (Basel). 2020 Dec 25;13(1):39. doi: 10.3390/cancers13010039.
Geissler K, Jäger E, Barna A, Gurbisz M, Graf T, Graf E, Nösslinger T, Pfeilstöcker M, Tüchler H, Sliwa T, Keil F, Geissler C, Heibl S, Thaler J, Machherndl-Spandl S, Zach O, Weltermann A, Bettelheim P, Stauder R, Zebisch A, Sill H, Schwarzinger I, Schneeweiss B, Öhler L, Ulsperger E, Kusec R, Germing U, Sperr WR, Knöbl P, Jäger U, Hörmann G, Valent P.
Correlation of RAS-Pathway Mutations and Spontaneous Myeloid Colony Growth with Progression and Transformation in Chronic Myelomonocytic Leukemia-A Retrospective Analysis in 337 Patients
Int J Mol Sci. 2020 Apr 24;21(8):3025. doi: 10.3390/ijms21083025.
Müller-Thomas C, Heider M, Piontek G, Schlensog M, Bassermann F, Kirchner T, Germing U, Götze KS, Rudelius M.
Prognostic value of indoleamine 2,3 dioxygenase in patients with higher-risk myelodysplastic syndromes treated with azacytidine
Br J Haematol. 2020 Aug;190(3):361-370. doi: 10.1111/bjh.16652. Epub 2020 Apr 29.
Whongsiri P, Goering W, Lautwein T, Hader C, Niegisch G, Köhrer K, Hoffmann MJ and Schulz WA
Many Different LINE-1 Retroelements Are Activated in Bladder Cancer
Int J Mol Sci 2020, 21, 9433
Bernard E, Nannya Y, Hasserjian RP, Devlin SM, Tuechler H, Medina-Martinez JS, Yoshizato T, Shiozawa Y, Saiki R, Malcovati L, Levine MF, Arango JE, Zhou Y, Solé F, Cargo CA, Haase D, Creignou M, Germing U, Zhang Y, Gundem G, Sarian A, van de Loosdrecht AA, Jädersten M, Tobiasson M, Kosmider O, Follo MY, Thol F, Pinheiro RF, Santini V, Kotsianidis I, Boultwood J, Santos FPS, Schanz J, Kasahara S, Ishikawa T, Tsurumi H, Takaori-Kondo A, Kiguchi T, Polprasert C, Bennett JM, Klimek VM, Savona MR, Belickova M, Ganster C, Palomo L, Sanz G, Ades L, Della Porta MG, Elias HK, Smith AG, Werner Y, Patel M, Viale A, Vanness K, Neuberg DS, Stevenson KE, Menghrajani K, Bolton KL, Fenaux P, Pellagatti A, Platzbecker U, Heuser M, Valent P, Chiba S, Miyazaki Y, Finelli C, Voso MT, Shih LY, Fontenay M, Jansen JH, Cervera J, Atsuta Y, Gattermann N, Ebert BL, Bejar R, Greenberg PL, Cazzola M, Hellström-Lindberg E, Ogawa S, Papaemmanuil E.
Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes
Nature Med. 2020;26:1549-1556.
Nini A, Hoffmann MJ, Lampignano R, Große Siemer R, van Dalum G, Szarvas T, Cotarelo CL, Schulz WA, Niederacher D, Neubauer H, Stoecklein NH, Niegisch G.
Evaluation of HER2 expression in urothelial carcinoma cells as a biomarker for circulating tumor cells
Cytometry B Clin Cytom. 2020 Jul;98(4):355-367. doi: 10.1002/cyto.b.21877. Epub 2020 Mar 25. PMID: 32212383
Morsch R, Rose M, Maurer A, Cassataro MA, Braunschweig T, Knüchel R, Vögeli TA, Ecke T, Eckstein M, Weyerer V, Esposito I, Ackermann M, Niegisch G, Gaisa NT; German Study Group of Bladder Cancer (DFBK e.V.).
Therapeutic implications of PD-L1 expression in bladder cancer with squamous differentiation
BMC Cancer. 2020 Mar 18;20(1):230. doi: 10.1186/s12885-020-06727-2. PMID: 32188412
Publikationen Biomaterialbank - 2019
Rautenberg C, Germing U, Pechtel S, Lamers M, Fischermanns C, Jäger P, Geyh S, Haas R, Kobbe G, Schroeder T.
Prognostic impact of peripheral blood WT1-mRNA expression in patients with MDS
Blood Cancer J. 2019 Nov 12;9(11):86. doi: 10.1038/s41408-019-0248-y
Ganster C, Müller-Thomas C, Haferlach C, Strupp C, Ogata K, Germing U, Hildebrandt B, Mallo M, Lübbert M, Müller C, Solé F, Götze KS, Vandenberghe P, Göhring G, Steinmetz T, Kröger N, Platzbecker U, Söling U, Raynaud S, Shirneshan K, Schanz J, Haase D.
Comprehensive analysis of isolated der(1;7)(q10;p10) in a large international homogenous cohort of patients with myelodysplastic syndromes
Genes Chromosomes Cancer. 2019 Oct;58(10):689-697. doi: 10.1002/gcc.22760. Epub 2019 Apr 30.
Mährle T, Akyüz N, Fuchs P, Bonzanni N, Simnica D, Germing U, Asemissen AM, Jann JC, Nolte F, Hofmann WK, Nowak D, Binder M.
Deep sequencing of bone marrow microenvironments of patients with del(5q) myelodysplastic syndrome reveals imprints of antigenic selection as well as generation of novel T-cell clusters as a response pattern to lenalidomide
Haematologica. 2019 Jul;104(7):1355-1364. doi: 10.3324/haematol.2018.208223. Epub 2019 Jan 17.
Hoell JI, Ginzel S, Kuhlen M, Kloetgen A, Gombert M, Fischer U, Hein D, Demir S, Stanulla M, Schrappe M, Zur Stadt U, Bader P, Babor F, Schuster F, Strahm B, Alten J, Moericke A, Escherich G, von Stackelberg A, Thiele R, McHardy AC, Peters C, Bornhauser B, Bourquin JP, Krause S, Enczmann J, Meyer LH, Eckert C, Borkhardt A, Meisel R.
Pediatric ALL relapses after allo-SCT show high individuality, clonal dynamics, selective pressure, and druggable targets
Blood Adv. 2019 Oct 22;3(20):3143-3156. doi: 10.1182/bloodadvances.2019000051. PMID: 31648313 Free PMC article.
Sassenberg M, Droop J, Schulz WA, Dietrich D, Loick SM, Wiek C, Scheckenbach K, Gaisa NT, Hoffmann MJ
Upregulation of the long non-coding RNA CASC9 as a biomarker for squamous cell carcinoma
BMC Cancer 2019 Aug 14;19(1):806
Publikationen Biomaterialbank - 2018
Geyh S, Rodríguez-Paredes M, Jäger P, Koch A, Bormann F, Gutekunst J, Zilkens C, Germing U, Kobbe G, Lyko F, Haas R, Schroeder T.
Transforming growth factor β1-mediated functional inhibition of mesenchymal stromal cells in myelodysplastic syndromes and acute myeloid leukemia 
Haematologica. Vol. 103 No. 9 (2018): September, 2018
Rautenberg C, Pechtel S, Hildebrandt B, Betz B, Dienst A, Nachtkamp K, Kondakci M, Geyh S, Wieczorek D, Haas R, Germing U, Kobbe G, Schroeder T.
Wilms' Tumor 1 Gene Expression Using a Standardized European LeukemiaNet-Certified Assay Compared to Other Methods for Detection of Minimal Residual Disease in Myelodysplastic Syndrome and Acute Myelogenous Leukemia after Allogeneic Blood Stem Cell Transplantation 
Biol Blood Marrow Transplant. 2018 May
Schuler E, Frank F, Hildebrandt B, Betz B, Strupp C, Rudelius M, Aul C, Schroeder T, Gattermann N, Haas R, Germing U.
Myelodysplastic syndromes without peripheral monocytosis but with evidence of marrow monocytosis share clinical and molecular characteristics with CMML
Leuk Res. 2018 Feb;65:1-4.
Kuendgen A, Müller-Thomas C, Lauseker M, Haferlach T, Urbaniak P, Schroeder T, Brings C, Wulfert M, Meggendorfer M, Hildebrandt B, Betz B, Royer-Pokora B, Gattermann N, Haas R, Germing U, Götze KS
Efficacy of azacitidine is independent of molecular and clinical characteristics - an analysis of 128 patients with myelodysplastic syndromes or acute myeloid leukemia and a review of the literature
Oncotarget. 2018 Jun 12;9(45):27882-27894
Kessler T, Sahm F, Sadik A, Stichel D, Hertenstein A, Reifenberger G, Zacher A, Sabel M, Tabatabai G, Steinbach J, Sure U, Krex D, Grosu AL, Bewerunge-Hudler M, Jones D, Pfister SM, Weller M, Opitz C, Bendszus M, von Deimling A, Platten M, Wick W.
Molecular differences in IDH wildtype glioblastoma according to MGMT promoter methylation
Neuro Oncol. 2018 Feb 19;20(3):367-379. doi: 10.1093/neuonc/nox160.
Dizdar L, Jünemann LM, Werner TA, Verde PE, Baldus SE, Stoecklein NH, Knoefel WT, Krieg A.
Clinicopathological and functional implications of the inhibitor of apoptosis proteins survivin and XIAP in esophageal cancer
Oncol Lett. 2018 Mar;15(3):3779-3789. doi: 10.3892/ol.2018.7755. Epub 2018 Jan 9.
Publikationen Biomaterialbank - 2017
Droop J, Szarvas T, Schulz WA, Niedworok C, Niegisch G, Scheckenbach K, Hoffmann MJ
Diagnostic and prognostic value of long noncoding RNAs as biomarkers in urothelial carcinoma
PLOS One 12(4):e0176287.
Felsberg J, Hentschel B, Kaulich K, Gramatzki D, Zacher A, Malzkorn B, Kamp M, Sabel M, Simon M, Westphal M, Schackert G, Tonn JC, Pietsch T, von Deimling A, Loeffler M, Reifenberger G, Weller M; German Glioma Network.
Epidermal Growth Factor Receptor Variant III (EGFRvIII) Positivity in EGFR-Amplified Glioblastomas: Prognostic Role and Comparison between Primary and Recurrent Tumors
Clin Cancer Res. 2017 Nov 15;23(22):6846-6855. doi: 10.1158/1078-0432.CCR-17-0890. Epub 2017 Aug 29
Erichsen L, Ghanjati F, Beermann A, Poyet C, Hermanns T, Schulz WA, Seifert HH, Wild P, Buser L, Kröning A, Braunstein S, Anlauf M, Jankowiak S, Hassan M, Bendhack M, Araúzo-Bravo M, Santourlidis S (2018)
Aberrant methylated key genes of methyl group metabolism within the molecular etiology of urothelial carcinogenesis
Sci. Rep. 22:3477.
Gramatzki D, Kickingereder P, Hentschel B, Felsberg J, Herrlinger U, Schackert G, Tonn JC, Westphal M, Sabel M, Schlegel U, Wick W, Pietsch T, Reifenberger G, Loeffler M, Bendszus M, Weller M.
Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma
Neurology. 2017 Apr 11;88(15):1422-1430. doi:10.1212/WNL.0000000000003809. Epub 2017 Mar 15
Rausch V, Krieg A, Camps J, Behrens B, Beier M, Wangsa D, Heselmeyer-Haddad K, Baldus SE, Knoefel WT, Ried T, Stoecklein NH.
Array comparative genomic hybridization of 18 pancreatic ductal adenocarcinomas and their autologous metastases 
BMC Res Notes. 2017 Nov 6;10(1):560. doi: 10.1186/s13104-017-2886-0.
Dizdar L, Tomczak M, Werner TA, Safi SA, Riemer JC, Verde PE, Stoecklein NH, Knoefel WT, Krieg A.
Survivin and XIAP expression in distinct tumor compartments of surgically resected gastric cancer: XIAP as a prognostic marker in diffuse and mixed type adenocarcinomas
Oncol Lett. 2017 Dec;14(6):6847-6856. doi: 10.3892/ol.2017.6999. Epub 2017 Sep 19.
Schumacher S, Bartenhagen C, Hoffmann M, Will D, Fischer JC, Baldus SE, Vay C, Fluegen G, Dizdar L, Vallböhmer D, Klein CA, Knoefel WT, Stoecklein NH, Möhlendick B.
Disseminated tumour cells with highly aberrant genomes are linked to poor prognosis in operable oesophageal adenocarcinoma
Br J Cancer. 2017 Aug 22;117(5):725-733. doi: 10.1038/bjc.2017.233.
Epub 2017 Jul 20.
Dizdar L, Oesterwind KA, Riemer JC, Werner TA, Mersch S, Möhlendick B, Schütte SC, Verde PE, Raba K, Topp SA, Stoecklein NH, Esposito I, Knoefel WT, Krieg  A.
Preclinical assesement of survivin and XIAP as prognostic biomarkers and therapeutic targets in gastroenteropancreatic neuroendocrine neoplasia
Oncotarget. 2017 Jan 31;8(5):8369-8382. doi: 10.18632/oncotarget.14207
Cheng JY, Brown TC, Murtha TD, Stenman A, Juhlin CC, Larsson C, Healy JM, Prasad ML, Knoefel WT, Krieg A, Scholl UI, Korah R, Carling T.
A novel FOXO1-mediated dedifferentiation blocking role for DKK3 in adrenocortical carcinogenesis
BMC Cancer. 2017 Mar 1;17(1):164. doi: 10.1186/s12885-017-3152-5.
Brychta N, Drosch M, Driemel C, Fischer JC, Neves RP, Esposito I, Knoefel WT, Möhlendick B, Hille C, Stresemann A, Krahn T, Kassack MU, Stoecklein NH, von Ahsen O.
Isolation of circulating tumor cells from pancreatic cancer by automated filtration
Oncotarget. 2017 Sep 16;8(49):86143-86156. doi:10.18632/oncotarget.21026. eCollection 2017 Oct 17.
Publikationen Biomaterialbank - 2016
Reusing SB, Manser AR, Enczmann J, Mulder A, Claas FH, Carrington M, Fischer JC, Borkhardt A, Babor F, Uhrberg M.
Selective downregulation of HLA-C and HLA-E in childhood acute lymphoblastic leukaemia
Br J Haematol. 2016 Aug;174(3):477-80. doi: 10.1111/bjh.13777. Epub 2015 Nov 3. PMID: 26527563 Free PMC article. No abstract available.
Wick W, Roth P, Hartmann C, Hau P, Nakamura M, Stockhammer F, Sabel MC, Wick A, Koeppen S, Ketter R, Vajkoczy P, Eyupoglu I, Kalff R, Pietsch T, Happold C, Galldiks N, Schmidt-Graf F, Bamberg M, Reifenberger G, Platten M, von Deimling A, Meisner C, Wiestler B, Weller M; Neurooncology Working Group (NOA) of the German Cancer Society 
Long-term analysis of the NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with PCV or temozolomide
Neuro Oncol. 2016 Nov;18(11):1529-1537. Epub 2016 Jul 1.
Herrlinger U, Schäfer N, Steinbach JP, Weyerbrock A, Hau P, Goldbrunner R, Friedrich F, Rohde V, Ringel F, Schlegel U, Sabel M, Ronellenfitsch MW, Uhl M, Maciaczyk J, Grau S, Schnell O, Hänel M, Krex D, Vajkoczy P, Gerlach R, Kortmann RD, Mehdorn M, Tüttenberg J, Mayer-Steinacker R, Fietkau R, Brehmer S, Mack F, Stuplich M, Kebir S, Kohnen R, Dunkl E, Leutgeb B, Proescholdt M, Pietsch T, Urbach H, Belka C, Stummer W, Glas M.
Bevacizumab Plus Irinotecan Versus Temozolomide in Newly Diagnosed O6-Methylguanine-DNA Methyltransferase Nonmethylated Glioblastoma: The Randomized GLARIUS Trial
J Clin Oncol. 2016 May 10;34(14):1611-9. doi: 10.1200/JCO.2015.63.4691. Epub 2016 Mar 14.
Schimmöller L, Quentin M, Blondin D, Dietzel F, Hiester A, Schleich C, Thomas C, Rabenalt R, Gabbert HE, Albers P, Antoch G, Arsov C.
Targeted MRI-guided prostate biopsy: are two biopsy cores per MRI-lesion required?
Eur Radiol. 2016 Nov;26(11):3858-3864. Epub 2016 Feb 26.
Publikationen Biomaterialbank - 2015
Heubach J, Monsior J, Deenen R, Niegisch G, Szarvas T, Niedworok C, Schulz WA, Hoffmann MJ
The long noncoding RNA HOTAIR has tissue and cell type-dependent effects on HOX gene expression and phenotype of urothelial cancer cells
Mol Cancer 21:108.
Hoffmann MJ, Dehn J, Droop J, Niegisch G, Niedworok C, Szarvas T, Schulz WA
Truncated Isoforms of lncRNA ANRIL Are Overexpressed in Bladder Cancer, But Do Not Contribute to Repression of INK4 Tumor Suppressors
Non-Coding RNA 1: 266-284.
Weller M, Tabatabai G, Kästner B, Felsberg J, Steinbach JP, Wick A, Schnell O, Hau P, Herrlinger U, Sabel MC, Wirsching HG, Ketter R, Bähr O, Platten M, Tonn JC, Schlegel U, Marosi C, Goldbrunner R, Stupp R, Homicsko K, Pichler J, Nikkhah G, Meixensberger J, Vajkoczy P, Kollias S, Hüsing J, Reifenberger G, Wick W; DIRECTOR Study Group.
MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial
Clin Cancer Res. 2015 May 1;21(9):2057-64. doi: 10.1158/1078-0432.CCR-14-2737. Epub 2015
Weller M, Weber RG, Willscher E, Riehmer V, Hentschel B, Kreuz M, Felsberg J, Beyer U, Löffler-Wirth H, Kaulich K, Steinbach JP, Hartmann C, Gramatzki D, Schramm J, Westphal M, Schackert G, Simon M, Martens T, Boström J, Hagel C, Sabel M, Krex D, Tonn JC, Wick W, Noell S, Schlegel U, Radlwimmer B, Pietsch T, Loeffler M, von Deimling A, Binder H, Reifenberger G.
Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups
Acta Neuropathol. 2015 May;129(5):679-93. doi: 10.1007/s00401-015-1409-0. Epub 2015 Mar 18
Arsov C, Becker N, Rabenalt R, Hiester A, Quentin M, Dietzel F, Antoch G, Gabbert HE, Albers P, Schimmöller L.
The use of targeted MR-guided prostate biopsy reduces the risk of Gleason upgrading on radical prostatectomy
J Cancer Res Clin Oncol. 2015 Nov;141(11):2061-8. doi: 10.1007/s00432-015-1991-5. Epub 2015 May 27.
Juhlin CC, Goh G, Healy JM, Fonseca AL, Scholl UI, Stenman A, Kunstman JW, Brown TC, Overton JD, Mane SM, Nelson-Williams C, Backdahl M, Suttorp AC, Haase M, Choi M, Schlessinger J, Rimm DL, Hoog A, Prasad ML, Korah R, Larsson C, Lifton RP, Carling T. 
Whole-exome sequencing characterizes the landscape of somatic mutations and copy number alterations in adrenocortical carcinoma
J Clin Endocrinol Metab. 2015 Mar;100(3):E493-502. doi: 10.1210/jc.2014-3282. Epub 2014 Dec 9.
Scholl UI, Healy JM, Thiel A, Fonseca AL, Brown TC, Kunstman JW, Horne MJ, Dietrich D, Riemer J, Kücükköylü S, Reimer EN, Reis AC, Goh G, Kristiansen G, Mahajan A, Korah R, Lifton RP, Prasad ML, Carling T.
Novel Somatic Mutations in Primary Hyperaldosteronism are related to the Clinical, Radiological and Pathological Phenotype
Clin Endocrinol (Oxf). 2015 Dec;83(6):779-89. doi: 10.1111/cen.12873. Epub 2015 Sep 23. 
Thiel A, Reis AC, Haase M, Goh G, Schott M, Willenberg HS, Scholl UI.
PRKACA mutations in cortisol-producing adenomas and adrenal hyperplasia: a single-center study of 60 cases
Eur J Endocrinol. 2015 Jun;172(6):677-85. doi: 10.1530/EJE-14-1113. Epub 2015 Mar 6.
Arsov C, Rabenalt R, Blondin D, Quentin M, Hiester A, Godehardt E, Gabbert HE, Becker N, Antoch G, Albers P, Schimmöller L.
Prospective randomized trial comparing magnetic resonance imaging (MRI)-guided in-bore biopsy to MRI-ultrasound fusion and transrectal ultrasound-guided prostate biopsy in patients with prior negative biopsies
Eur Urol. 2015 Oct;68(4):713-20. doi: 10.1016/j.eururo.2015.06.008. Epub 2015 Jun 23.
Publikationen Biomaterialbank - 2014
Babor F, Manser AR, Fischer JC, Scherenschlich N, Enczmann J, Chazara O, Moffett A, Borkhardt A, Meisel R, Uhrberg M.
KIR ligand C2 is associated with increased susceptibility to childhood ALL and confers an elevated risk for late relapse
Blood. 2014 Oct 2;124(14):2248-51. doi: 10.1182/blood-2014-05-572065. Epub 2014 Aug 27.
PMID: 25163702 Free article
Arsov C, Jankowiak F, Hiester A, Rabenalt R, Quentin M, Schimmöller L, Blondin D, Antoch G, Albers P.
Anticancer Prognostic value of a cell-cycle progression score in men with prostate cancer managed with active surveillance after MRI-guided prostate biopsy--a pilot study
Res. 2014 May;34(5):2459-66.
Goh G, Scholl UI, Healy JM, Choi M, Prasad ML, Nelson-Williams C, Kunstman JW, Korah R, Suttorp AC, Dietrich D, Haase M, Willenberg HS, Stalberg P, Hellman P, Akerstrom G, Bjorklund P, Carling T, Lifton RP
Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumors
Nat Genet. 2014 Jun;46(6):613-7. doi: 10.1038/ng.2956. Epub 2014 Apr 20.
Reifenberger G, Weber RG, Riehmer V, Kaulich K, Willscher E, Wirth H, Gietzelt J, Hentschel B, Westphal M, Simon M, Schackert G, Schramm J, Matschke J, Sabel MC, Gramatzki D, Felsberg J, Hartmann C, Steinbach JP, Schlegel U, Wick W, Radlwimmer B, Pietsch T, Tonn JC, von Deimling A, Binder H, Weller M, Loeffler M; German Glioma Network.
Molecular characterization of long-term survivors of glioblastoma using genome- and transcriptome-wide profiling
Int J Cancer. 2014 Oct 15;135(8):1822-31. doi: 10.1002/ijc.28836. Epub 2014 Mar 28
Greife A, Jankowiak S, Steinbring J, Nikpour P, Niegisch G, Hoffmann MJ, Schulz WA (2014) 
Canonical Notch signalling is inactive in urothelial carcinoma
BMC Cancer. 2014 Aug 29;14:628. doi: 10.1186/1471-2407-14-628
Publikationen Biomaterialbank - 2013
Vinarskaja A, Schulz WA, Ingenwerth M, Hader C, Arsov C.
Association of PITX2 mRNA down-regulation in prostate cancer with promoter hypermethylation and poor prognosis
Urol Oncol. 2013 Jul;31(5):622-7. doi: 10.1016/j.urolonc.2011.04.010. Epub 2011 Jul 30.
Publikationen Biomaterialbank - 2012
Arsov C1, Quentin M, Rabenalt R, Antoch G, Albers P, Blondin D.
Repeat transrectal ultrasound biopsies with additional targeted cores according to results of functional prostate MRI detects high-risk prostate cancer in patients with previous negative biopsy and increased PSA - a pilot study
Anticancer Res. 2012 Mar;32(3):1087-92

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