Publikationen 2023
IL-6 in the infarcted heart is preferentially formed by fibroblasts and is modulated by purinergic signaling. Alter C, Henseler AS, Owenier C, Hesse J, Ding Z, Lautwein T, Bahr J, Hayat S, Kramann R, Kostenis E, Scheller J, Schrader J.J Clin Invest. 2023 Mar 21:e163799. doi: 10.1172/JCI163799. Online ahead of print.
Pancreatic islet protection at the expense of secretory function involves serine-linked mitochondrial one-carbon metabolism.Pelligra A, Mrugala J, Griess K, Kirschner P, Nortmann O, Bartosinska B, Köster A, Krupenko NI, Gebel D, Westhoff P, Steckel B, Eberhard D, Herebian D, Belgardt BF, Schrader J, Weber APM, Krupenko SA, Lammert E.Cell Rep. 2023 Jun 27;42(6):112615. doi: 10.1016/j.celrep.2023.112615. Epub 2023 Jun 8.PMID: 37294632
CD73 deficiency does not aggravate angiotensin II-induced aortic inflammation in mice. Massold T, Ibrahim F, Niemann V, Steckel B, Becker K, Schrader J, Stegbauer J, Temme S, Grandoch M, Flögel U, Bouvain P. PMID: 37816827 PMCID: PMC10564884 DOI: 10.1038/s41598-023-44361-7
Non-invasive mapping of systemic neutrophil dynamics upon cardiovascular injury, Pascal Bouvain,Zhaoping Ding,Shiwa Kadir,Patricia Kleimann,Nils Kluge,Zeynep-Büsra Tiren,Bodo Steckel,Vera Flocke,Ria Zalfen,Patrick Petzsch,Thorsten Wachtmeister,Gordon John,Nirojah Subramaniam,Wolfgang Krämer,Tobias Strasdeit,Mehrnaz Mehrabipour,Jens M. Moll,Rolf Schubert,Mohammad Reza Ahmadian,Florian Bönner,Udo Boeken,Ralf Westenfeld,Daniel Robert Engel,Malte Kelm,Jürgen Schrader,Karl Köhrer,Maria Grandoch,Sebastian Temme &Ulrich Flögel, Nature Cardiovascular Research volume 2, pages126–143 (2023
Biodegradable polyphosphoester micelles act as both background-free 31P magnetic resonance imaging agents and drug nanocarriers. Koshkina O, Rheinberger T, Flocke V, Windfelder A, Bouvain P, Hamelmann NM, Paulusse JMJ, Gojzewski H, Flögel U, Wurm FR.Nat Commun. 2023 Jul 19;14(1):4351. doi: 10.1038/s41467-023-40089-0.PMID: 37468502
A quantitative micro-tomographic gut atlas of the lepidopteran model insect Manduca sexta.Windfelder AG, Steinbart J, Flögel U, Scherberich J, Kampschulte M, Krombach GA, Vilcinskas A.iScience. 2023 May 5;26(6):106801. doi: 10.1016/j.isci.2023.106801. eCollection 2023 Jun 16.PMID: 37378344
Linsitinib, an IGF-1R inhibitor, attenuates disease development and progression in a model of thyroid eye disease. Gulbins A, Horstmann M, Daser A, Flögel U, Oeverhaus M, Bechrakis NE, Banga JP, Keitsch S, Wilker B, Krause G, Hammer GD, Spencer AG, Zeidan R, Eckstein A, Philipp S, Görtz GE.Front Endocrinol (Lausanne). 2023 Jun 26;14:1211473. doi: 10.3389/fendo.2023.1211473. eCollection 2023.PMID: 37435490
Noninvasive assessment of metabolic turnover during inflammation by in vivo deuterium magnetic resonance spectroscopy. Flocke V, Temme S, Bouvain P, Grandoch M, Flögel U.Front Immunol. 2023 Sep 28;14:1258027. doi: 10.3389/fimmu.2023.1258027. eCollection 2023.PMID: 37841266
The Endogenous Dual Retinoid Receptor Agonist Alitretinoin Exhibits Immunoregulatory Functions on Antigen-Presenting Cells Andreas Kislat 1, Peter Olah 1 2, Marcus Kuchner 1, Peter Arne Gerber 1, Jürgen Schrader 3, Stephan Meller 1, Bernhard Homey 1 Affiliations expand PMID: 37298605 PMCID: PMC10253969 DOI: 10.3390/ijms24119654
Quantitative assessment of angioplasty-induced vascular inflammation with (19)F cardiovascular magnetic resonance imaging.Nienhaus F, Walz M, Rothe M, Jahn A, Pfeiler S, Busch L, Stern M, Heiss C, Vornholz L, Cames S, Cramer M, Schrauwen-Hinderling V, Gerdes N, Temme S, Roden M, Flögel U, Kelm M, Bönner F.J Cardiovasc Magn Reson. 2023 Oct 3;25(1):54. doi: 10.1186/s12968-023-00964-7.PMID: 37784080.
Constitutive Activation of gp130 in T Cells Results in Senescence and Premature Aging. Rafii P, Reusswig F, Werner J, Xu H, Lang PA, Rose-John S, Gorressen S, Alter C, Schrader J, Herebian D, Floss DM, Elvers M, Piekorz RP, Scheller J, Behnke K.J Immunol. 2023 Jun 1;210(11):1641-1652. doi: 10.4049/jimmunol.2200788.PMID: 37058108
In Vivo Mapping of Deep Tissue pO(2) in a Murine Model of Peripheral Artery Disease by Noninvasive (19)F MR Relaxometry. Stumpe N, Güden-Silber T, Schneckmann R, Wolters K, Lamb H, Grandoch M, Flögel U.Arterioscler Thromb Vasc Biol. 2023 Apr;43(4):597-598. doi: 10.1161/ATVBAHA.122.318548. Epub 2023 Feb 9.PMID: 36756882
SYSTEMI - systemic organ communication in STEMI: design and rationale of a cohort study of patients with ST-segment elevation myocardial infarction.Bönner F, Jung C, Polzin A, Erkens R, Dannenberg L, Ipek R, Kaldirim M, Cramer M, Wischmann P, Zaharia OP, Meyer C, Flögel U, Levkau B, Gödecke A, Fischer J, Klöcker N, Krüger M, Roden M, Kelm M.BMC Cardiovasc Disord. 2023 May 3;23(1):232. doi: 10.1186/s12872-023-03210-1.PMID: 37138228
Rivaroxaban attenuates neutrophil maturation in the bone marrow niche.Schneckmann R, Döring M, Gerfer S, Gorressen S, Heitmeier S, Helten C, Polzin A, Jung C, Kelm M, Fender AC, Flögel U, Grandoch M.Basic Res Cardiol. 2023 Aug 14;118(1):31. doi: 10.1007/s00395-023-01001-5.PMID: 3758050
Pancreatic islet protection at the expense of secretory function involves serine-linked mitochondrial one-carbon metabolism. Pelligra A, Mrugala J, Griess K, Kirschner P, Nortmann O, Bartosinska B, Köster A, Krupenko NI, Gebel D, Westhoff P, Steckel B, Eberhard D, Herebian D, Belgardt BF, Schrader J, Weber APM, Krupenko SA, Lammert E.Cell Rep. 2023 Jun 27;42(6):112615. doi: 10.1016/j.celrep.2023.112615. Epub 2023 Jun 8.PMID: 37294632
Real-time (31)P NMR reveals different gradient strengths in polyphosphoester copolymers as potential MRI-traceable nanomaterials. Rheinberger T, Flögel U, Koshkina O, Wurm FR.Commun Chem. 2023 Sep 1;6(1):182. doi: 10.1038/s42004-023-00954-x.PMID: 37658116
Data on common carotid artery occlusion inducing focalized stroke lesions after Pertussis toxin injection. Leiss V, Piekorz RP, Vega SC, Jacoby C, Flögel U, Pexa K, Schrader J, Pichler BJ, Beer-Hammer S, Nürnberg B.Data Brief. 2022 Dec 25;46:108851. doi: 10.1016/j.dib.2022.108851. eCollection 2023 Feb.PMID: 36624761
Sphingosine-1-phosphate improves outcome of no-reflow acute myocardial infarction via sphingosine-1-phosphate receptor 1. Polzin A, Dannenberg L, Benkhoff M, Barcik M, Keul P, Ayhan A, Weske S, Ahlbrecht S, Trojovsky K, Helten C, Haberkorn S, Flögel U, Zeus T, Müller T, Gräler MH, Kelm M, Levkau B.ESC Heart Fail. 2023 Feb;10(1):334-341. doi: 10.1002/ehf2.14176. Epub 2022 Oct 11.PMID: 36217778