Publikationen

Augustin M, Herberger K, Wille A, Twarock S, Impact of human wound exudate on the bactericidal efficacy of commercial antiseptic products. J Wound Care, 2023. 32(7): p. 422-427. PMID: 37405941

Vogeley C*, Degistirici Ö*, Twarock S*, Wladarz J, Reiners O, Gorges T, 
Fischer JW, Meisel R, Gorges K. The regulatory effect of hyaluronan on human mesenchymal stem cells' fate modulates their interaction with cancer cells in vitro. Sci Rep. 2021 Oct 27;11(1):21229. PMID: 34707175

Kohlmorgen C, Gerfer S, Feldmann K, Twarock S, Hartwig S, Lehr S, Klier M, Krüger I, Helten C, Keul P, Kahl S, Polzin A, Elvers M, Flögel U, Kelm M, 
Levkau B, Roden M, Fischer JW, Grandoch M. Dapagliflozin reduces thrombin generation and platelet activation: implications for cardiovascular risk reduction in type 2 diabetes mellitus. Diabetologia. 2021 Aug;64(8):1834-1849. 
PMID: 34131781

Jäger P, Geyh S, Twarock S, Cadeddu R, Rabes P, Koch A, Maus U, Hesper T, Zilkens C, Rautenberg C, Bormann F, Köhrer K, Petzsch P, Wieczorek D, 
Betz B, Surowy H, Hildebrandt B, Germing U, Kobbe G, Haas R, Schroeder T. Acute myeloid leukemia-induced functional inhibition of healthy CD34+ hematopoietic stem and progenitor cells. Stem Cells. 2021 Sep;39(9):1270-1284. PMID: 34013984

Gholamreza-Fahimi E, Bisha M, Hahn J, Straßen U, Krybus M, Khosravani F, Hoffmann TK, Hohlfeld T, Greve J, Bas M, Twarock S#, Kojda G#.
Cyclooxygenase activity in bradykinin-induced dermal extravasation. A study 
in mice and humans. Biomed Pharmacother. 2020 Mar;123:109797.
PMID: 31874445

Twarock S*, Reichert C*, Bach K, Reiners O, Kretschmer I, Gorski DJ, 
Gorges K, Grandoch M, Fischer JW. Inhibition of the hyaluronan matrix enhances metabolic anticancer therapy by dichloroacetate in vitro and in vivo. 
Br J Pharmacol. 2019 Dec;176(23):4474-4490. PMID: 31351004

Gorges K, Wiltfang L, Gorges TM, Sartori A, Hildebrandt L, Keller L, Volkmer B, Peine S, Babayan A, Moll I, Schneider SW, Twarock S, Mohr P, Fischer JW, Pantel K. Intra-Patient Heterogeneity of Circulating Tumor Cells and 
Circulating Tumor DNA in Blood of Melanoma Patients. Cancers (Basel). 2019 Oct 29;11(11). PMID: 31671846

Gorski DJ, Petz A, Reichert C, Twarock S, Grandoch M, Fischer JW. Cardiac fibroblast activation and hyaluronan synthesis in response to hyperglycemia 
and diet-induced insulin resistance. Sci Rep. 2019 Feb 12;9(1):1827.
PMID: 30755628

Twarock S, Reichert C, Peters U, Gorski DJ, Röck K, Fischer JW. Hyperglycaemia and aberrated insulin signalling stimulate tumour progression via induction of the extracellular matrix component hyaluronan. Int J Cancer. 2017 Aug 15;141(4):791-804. PMID: 28493326

Schütze A, Vogeley C, Gorges T, Twarock S, Butschan J, Babayan A, Klein D, Knauer SK, Metzen E, Müller V, Jendrossek V, Pantel K, Milde-Langosch K, Fischer JW, Röck K. RHAMM splice variants confer radiosensitivity in 
human breast cancer cell lines. Oncotarget. 2016 Apr 19;7(16):21428-40. 
PMID: 26870892

Kretschmer I, Freudenberger T, Twarock S, Yamaguchi Y, Grandoch M, 
Fischer JW. Esophageal Squamous Cell Carcinoma Cells Modulate Chemokine Expression and Hyaluronan Synthesis in Fibroblasts. J Biol Chem. 2016 
Feb 19;291(8):4091-106. PMID: 26699196

Kiene LS, Homann S, Suvorava T, Rabausch B, Müller J, Kojda G, Kretschmer I, Twarock S, Dai G, Deenen R, Hartwig S, Lehr S, Köhrer K, Savani RC, 
Grandoch M, Fischer JW. Deletion of Hyaluronan Synthase 3 Inhibits Neointimal Hyperplasia in Mice. Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):e9-16 PMID: 26586662

Kretschmer I, Freudenberger T, Twarock S, Fischer JW. Synergistic effect 
of targeting the epidermal growth factor receptor and hyaluronan synthesis in oesophageal squamous cell carcinoma cells. Br J Pharmacol. 2015 Sep;172(18):4560-4574. PMID: 26140525

Twarock S, Freudenberger T, Poscher E, Dai G, Jannasch K, Dullin C, 
Alves F, Prenzel K, Knoefel WT, Stoecklein NH, Savani RC, Homey B, 
Fischer JW. Inhibition of oesophageal squamous cell carcinoma progression by in vivo targeting of hyaluronan synthesis. Mol Cancer. 2011 Mar 23;10:30. 
PMID: 21429221

Twarock S, Tammi MI, Savani RC, Fischer JW. Hyaluronan stabilizes focal adhesions, filopodia, and the proliferative phenotype in esophageal 
squamous carcinoma cells. J Biol Chem. 2010 Jul 23;285(30):23276-84.
PMID: 20463012

Twarock S, Röck K, Sarbia M, Weber AA, Jänicke RU, Fischer JW. Synthesis
of hyaluronan in oesophageal cancer cells is uncoupled from the 
prostaglandin-cAMP pathway. Br J Pharmacol. 2009 May;157(2):234-43. 
PMID: 19338584

Dai G, Freudenberger T, Zipper P, Melchior A, Grether-Beck S, Rabausch B, 
de Groot J, Twarock S, Hanenberg H, Homey B, Krutmann J, Reifenberger J, Fischer JW. Chronic ultraviolet B irradiation causes loss of hyaluronic acid 
from mouse dermis because of down-regulation of hyaluronic acid synthases. Am J Pathol. 2007 Nov;171(5):1451-61. PMID: 17982124

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