Publikationen
Augustin M, Herberger K, Wille A, Twarock S, Impact of human wound exudate on the bactericidal efficacy of commercial antiseptic products. J Wound Care, 2023. 32(7): p. 422-427. PMID: 37405941
Vogeley C*, Degistirici Ö*, Twarock S*, Wladarz J, Reiners O, Gorges T,
Fischer JW, Meisel R, Gorges K. The regulatory effect of hyaluronan on human mesenchymal stem cells' fate modulates their interaction with cancer cells in vitro. Sci Rep. 2021 Oct 27;11(1):21229. PMID: 34707175
Kohlmorgen C, Gerfer S, Feldmann K, Twarock S, Hartwig S, Lehr S, Klier M, Krüger I, Helten C, Keul P, Kahl S, Polzin A, Elvers M, Flögel U, Kelm M,
Levkau B, Roden M, Fischer JW, Grandoch M. Dapagliflozin reduces thrombin generation and platelet activation: implications for cardiovascular risk reduction in type 2 diabetes mellitus. Diabetologia. 2021 Aug;64(8):1834-1849.
PMID: 34131781
Jäger P, Geyh S, Twarock S, Cadeddu R, Rabes P, Koch A, Maus U, Hesper T, Zilkens C, Rautenberg C, Bormann F, Köhrer K, Petzsch P, Wieczorek D,
Betz B, Surowy H, Hildebrandt B, Germing U, Kobbe G, Haas R, Schroeder T. Acute myeloid leukemia-induced functional inhibition of healthy CD34+ hematopoietic stem and progenitor cells. Stem Cells. 2021 Sep;39(9):1270-1284. PMID: 34013984
Gholamreza-Fahimi E, Bisha M, Hahn J, Straßen U, Krybus M, Khosravani F, Hoffmann TK, Hohlfeld T, Greve J, Bas M, Twarock S#, Kojda G#.
Cyclooxygenase activity in bradykinin-induced dermal extravasation. A study
in mice and humans. Biomed Pharmacother. 2020 Mar;123:109797.
PMID: 31874445
Twarock S*, Reichert C*, Bach K, Reiners O, Kretschmer I, Gorski DJ,
Gorges K, Grandoch M, Fischer JW. Inhibition of the hyaluronan matrix enhances metabolic anticancer therapy by dichloroacetate in vitro and in vivo.
Br J Pharmacol. 2019 Dec;176(23):4474-4490. PMID: 31351004
Gorges K, Wiltfang L, Gorges TM, Sartori A, Hildebrandt L, Keller L, Volkmer B, Peine S, Babayan A, Moll I, Schneider SW, Twarock S, Mohr P, Fischer JW, Pantel K. Intra-Patient Heterogeneity of Circulating Tumor Cells and
Circulating Tumor DNA in Blood of Melanoma Patients. Cancers (Basel). 2019 Oct 29;11(11). PMID: 31671846
Gorski DJ, Petz A, Reichert C, Twarock S, Grandoch M, Fischer JW. Cardiac fibroblast activation and hyaluronan synthesis in response to hyperglycemia
and diet-induced insulin resistance. Sci Rep. 2019 Feb 12;9(1):1827.
PMID: 30755628
Twarock S, Reichert C, Peters U, Gorski DJ, Röck K, Fischer JW. Hyperglycaemia and aberrated insulin signalling stimulate tumour progression via induction of the extracellular matrix component hyaluronan. Int J Cancer. 2017 Aug 15;141(4):791-804. PMID: 28493326
Schütze A, Vogeley C, Gorges T, Twarock S, Butschan J, Babayan A, Klein D, Knauer SK, Metzen E, Müller V, Jendrossek V, Pantel K, Milde-Langosch K, Fischer JW, Röck K. RHAMM splice variants confer radiosensitivity in
human breast cancer cell lines. Oncotarget. 2016 Apr 19;7(16):21428-40.
PMID: 26870892
Kretschmer I, Freudenberger T, Twarock S, Yamaguchi Y, Grandoch M,
Fischer JW. Esophageal Squamous Cell Carcinoma Cells Modulate Chemokine Expression and Hyaluronan Synthesis in Fibroblasts. J Biol Chem. 2016
Feb 19;291(8):4091-106. PMID: 26699196
Kiene LS, Homann S, Suvorava T, Rabausch B, Müller J, Kojda G, Kretschmer I, Twarock S, Dai G, Deenen R, Hartwig S, Lehr S, Köhrer K, Savani RC,
Grandoch M, Fischer JW. Deletion of Hyaluronan Synthase 3 Inhibits Neointimal Hyperplasia in Mice. Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):e9-16 PMID: 26586662
Kretschmer I, Freudenberger T, Twarock S, Fischer JW. Synergistic effect
of targeting the epidermal growth factor receptor and hyaluronan synthesis in oesophageal squamous cell carcinoma cells. Br J Pharmacol. 2015 Sep;172(18):4560-4574. PMID: 26140525
Twarock S, Freudenberger T, Poscher E, Dai G, Jannasch K, Dullin C,
Alves F, Prenzel K, Knoefel WT, Stoecklein NH, Savani RC, Homey B,
Fischer JW. Inhibition of oesophageal squamous cell carcinoma progression by in vivo targeting of hyaluronan synthesis. Mol Cancer. 2011 Mar 23;10:30.
PMID: 21429221
Twarock S, Tammi MI, Savani RC, Fischer JW. Hyaluronan stabilizes focal adhesions, filopodia, and the proliferative phenotype in esophageal
squamous carcinoma cells. J Biol Chem. 2010 Jul 23;285(30):23276-84.
PMID: 20463012
Twarock S, Röck K, Sarbia M, Weber AA, Jänicke RU, Fischer JW. Synthesis
of hyaluronan in oesophageal cancer cells is uncoupled from the
prostaglandin-cAMP pathway. Br J Pharmacol. 2009 May;157(2):234-43.
PMID: 19338584
Dai G, Freudenberger T, Zipper P, Melchior A, Grether-Beck S, Rabausch B,
de Groot J, Twarock S, Hanenberg H, Homey B, Krutmann J, Reifenberger J, Fischer JW. Chronic ultraviolet B irradiation causes loss of hyaluronic acid
from mouse dermis because of down-regulation of hyaluronic acid synthases. Am J Pathol. 2007 Nov;171(5):1451-61. PMID: 17982124