Details zu geförderten Verbund-Projekten

Start: 01.01.2020

Laufzeit: 3 Jahre

Verbundprojekt a. AG Borkhardt

“Structural variant discovery in families with acute lymphoblastic leukemia by optical mapping and long-read sequencing”

“Molecular characterization of diagnostic and predictive genomic structural variations in low-grade neuroepithelial tumors using long-read next generation sequencing and optical mapping”

“Identification and characterization of genomic structural variations in pediatric malignant brain tumors”

“New algorithms for structural variant discovery in cancer genomes using optical mapping and long read data”

  • Prof. Dr. rer. nat. Gunnar Klau,
    (Institute of Computer Science, Workgroup Algorithmic Bioinformatics)

Verbundprojekt b. AG Wesselborg

“Identification of novel apoptosis signaling pathways for the elimination of therapy resistant tumors”

“Targeting mechanisms of the DNA damage response (DDR) to increase the therapeutic efficacy of conventional anticancer therapeutics”

  • Prof. Dr. rer. nat. Gerhard Fritz,
    (Institute of Toxicology)

“Targeting the autophagy-initiating class III PtdIns3K complex for cancer therapy”

“Targeting heat shock proteins in therapy resistant BCP-ALL”

  • Dr. rer. nat. Sanil Bhatia,
    (Clinic for Pediatric Oncology, Hematology & Clin. Immunology)
  • Prof. Dr. rer. nat. Holger Gohlke,
    (Institute of Pharmaceutical and Medicinal Chemistry)
  • Prof. Dr. rer. nat. Thomas Kurz,
    (Institute of Pharmaceutical and Medicinal Chemistry)
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