Publications Group Brenneisen

2024

Ebbert L, von Montfort C, Wenzel CK, Reichert AS, Stahl W, Brenneisen P. A Combination of Cardamonin and Doxorubicin Selectively Affect Cell Viability of Melanoma Cells: An In Vitro Study. Antioxidants (Basel). 2024 Jul 19;13(7):864. doi: 10.3390/antiox13070864. PMID: 39061932.

von Montfort C, Aplak E, Ebbert L, Wenzel CK, Klahm NP, Stahl W, Brenneisen P. The role of GAPDH in the selective toxicity of CNP in melanoma cells. PLoS One. 2024 Mar 21;19(3):e0300718. doi: 10.1371/journal.pone.0300718. PMID: 38512909.

2023

Jochims F, Strohm R, von Montfort C, Wenzel C-K, Klahm N, Kondadi AK, Stahl W, Reichert AS, Brenneisen P. The Antimalarial Drug Artesunate Mediates Selective Cytotoxicity by Upregulating HO-1 in Melanoma Cells. Biomedicines. 2023; 11(9):2393. PMID: 37760834.

Wenzel CK, von Montfort C, Ebbert L, Klahm NP, Reichert AS, Stahl W, Brenneisen P. The natural chalcone cardamonin selectively induces apoptosis in human neuroblastoma cells. Toxicol In Vitro. 2023 Sep;91:105625. doi: 10.1016/j.tiv.2023.105625. Epub 2023 Jun 1. PMID: 37268255.

Haasler L, von Montfort C, Kondadi AK, Golombek M, Ebbert L, Wenzel CK, Stahl W, Reichert AS, Brenneisen P. Involvement of necroptosis in the selective toxicity of the natural compound (±) gossypol on squamous skin cancer cells in vitro. Arch Toxicol. 2023 Jul;97(7):1997-2014. doi: 10.1007/s00204-023-03516-1. Epub 2023 May 21. PMID: 37210688.

Wedekind R, Fischer A, Mewes KR, Brenneisen P, Holtkötter O. Investigating the surfactant antagonism with the Open Source Reconstructed Epidermis (OS-Rep) model. Toxicol In Vitro. 2023 Apr;88:105557. doi: 10.1016/j.tiv.2023.105557. Epub 2023 Jan 18. PMID: 36681289.

2021

Stucki D, Westhoff P, Brilhaus D, Weber APM, Brenneisen P, Stahl W. Carbon monoxide exposure activates ULK1 via AMPK phosphorylation in murine embryonic fibroblasts. Int J Vitam Nutr Res. 2023 Apr;93(2):122-131. doi: 10.1024/0300-9831/a000714. Epub 2021 Jun 2. PMID: 34074127.

Haasler L, Kondadi AK, Tsigaras T, von Montfort C, Graf P, Stahl W, Brenneisen P. The BH3 mimetic (±) gossypol induces ROS-independent apoptosis and mitochondrial dysfunction in human A375 melanoma cells in vitro. Arch Toxicol. 2021 Apr;95(4):1349-1365. doi: 10.1007/s00204-021-02987-4. Epub 2021 Feb 1. PMID: 33523262.

2020

Drews L, Zimmermann M, Westhoff P, Brilhaus D, Poss RE, Bergmann L, Wiek C, Brenneisen P, Piekorz RP, Mettler-Altmann T, Weber APM, Reichert AS. Ammonia inhibits energy metabolism in astrocytes in a rapid and glutamate dehydrogenase 2-dependent manner. Dis Model Mech. 2020 Sep 11:dmm.047134. doi: 10.1242/dmm.047134. Epub ahead of print. PMID: 32917661.

Stucki D, Steinhausen J, Westhoff P, Krahl H, Brilhaus D, Massenberg A, Weber APM, Reichert AS, Brenneisen P, Stahl W. Endogenous carbon monoxide signaling modulates mitochondrial function and intracellular glucose utilization: Impact of the heme oxigenase substrate hemin. Antioxidants 2020, 9(8), 652; doi.org/10.3390/antiox9080652. PMID: 32717801.

Stucki D, Krahl H, Walter M, Steinhausen J, Hommel K, Brenneisen P, Stahl W. Effects of frequently applied carbon monoxide releasing molecules (CORMs) in typical CO-sensitive model systems - A comparative in vitro study. Arch Biochem Biophys. 2020 Apr 23;687:108383. doi: 10.1016/j.abb.2020.108383. PMID: 32335048.

Aplak E, von Montfort C, Haasler L, Stucki D, Steckel B, Reichert AS, Stahl W, Brenneisen P. CNP mediated selective toxicity on melanoma cells is accompanied by mitochondrial dysfunction. PLoS One. 2020 Jan 17;15(1):e0227926. doi: 10.1371/journal.pone.0227926. PMID: 31951630.

2019

Berning L, Scharf L, Aplak E, Stucki D, von Montfort C, Reichert AS, Stahl W, Brenneisen P. In vitro selective cytotoxicity of the dietary chalcone cardamonin (CD) on melanoma compared to healthy cells is mediated by apoptosis. PLoS One. 2019 Sep 25;14(9):e0222267. doi: 10.1371/journal.pone.0222267. PMID: 31553748.

Walter M, Stahl W, Brenneisen P, Reichert AS, Stucki D. Carbon monoxide releasing molecule 401 (CORM-401) modulates phase I metabolism of xenobiotics. Toxicol In Vitro. 2019 Apr 17; 59:215-220. doi: 10.1016/j.tiv.2019.04.018. PMID: 31004742.

2018

Stucki D, Brenneisen P, Reichert AS, Stahl W. The BH3 mimetic compound BH3I-1 impairs mitochondrial dynamics and promotes stress response in addition to its pro-apoptotic key function. Toxicol Lett. 2018 Oct 1;295:369-378. Epub 2018 Jul 18. doi: 10.1016/j.toxlet.2018.07.017. PMID: 30031050.

Brenneisen P, Reichert AS. Nanotherapy and Reactive Oxygen Species (ROS) in Cancer: A Novel Perspective. Antioxidants (Basel). 2018 Feb 22;7(2). pii: E31. PMID: 29470419.

2017

Sack-Zschauer M, Bader S, Brenneisen P. Cerium Oxide Nanoparticles as Novel Tool in Glioma Treatment: An In vitro Study. J Nanomed Nanotechnol. 2017 8:474. doi: 10.4172/2157-7439.1000474.

Sack-Zschauer M, Karaman-Aplak E, Wyrich C, Das S, Schubert T, Meyer H, Janiak C, Seal S, Stahl W, Brenneisen P. Efficacy of Different Compositions of Cerium Oxide Nanoparticles in Tumor-Stroma Interaction. J Biomed Nanotechnol. 2017 Dec 1;13(12):1735-1746. doi: 10.1166/jbn.2017.2452. PMID: 29490761.

Schneider LA, Raizner K, Wlaschek M, Brenneisen P, Gethöffer K, Scharffetter-Kochanek K. UVA-1 exposure in vivo leads to an IL-6 surge within the skin. Exp Dermatol. 2017 Sep;26(9):830-832. Epub 2017 Apr 11. PMID: 28094867.

2016

Diekmann J, Alili L, Scholz O, Giesen M, Holtkötter O, Brenneisen P. A three-dimensional skin equivalent reflecting some aspects of in vivo aged skin. Exp Dermatol. 2016 Jan;25(1):56-61. Epub 2015 Nov 23. PMID: 26440058.

2015

Alili L, Chapiro S, Marten GU, Schmidt AM, Zanger K, Brenneisen P. Effect of Fe3O4 Nanoparticles on Skin Tumor Cells and Dermal Fibroblasts. Biomed Res Int. 2015;2015:530957. Epub 2015 May 21. doi: 10.1155/2015/530957.  PMID: 26090418.

von Montfort C, Alili L, Teuber-Hanselmann S, Brenneisen P. Redox-active cerium oxide nanoparticles protect human dermal fibroblasts from PQ-induced damage. Redox Biol. 2015;4:1-5. Epub 2014 Nov 22. doi: 10.1016/j.redox.2014.11.007. PubMed PMID: 25479549.

2014

Alili L, Diekmann J, Giesen M, Holtkötter O, Brenneisen P. A drug-induced accelerated senescence (DIAS) is a possibility to study aging in time lapse. Age (Dordr). 2014 Jun;36(3):9658. Epub 2014 May 16. doi: 10.1007/s11357-014-9658-8. PMID: 24833306.

Sack M, Alili L, Karaman E, Das S, Gupta A, Seal S, Brenneisen P. Combination of conventional chemotherapeutics with redox-active cerium oxide nanoparticles--a novel aspect in cancer therapy. Mol Cancer Ther. 2014 Jul;13(7):1740-9. Epub 2014 May 13. doi: 10.1158/1535-7163. PubMed PMID: 24825856.

Alili L, Sack M, Puschmann K, Brenneisen P. Fibroblast-to-myofibroblast switch is mediated by NAD(P)H oxidase generated reactive oxygen species. Biosci Rep. 2014 Feb 1;34(1). pii: e00089. Print 2014 Feb 1. PMID: 27919042.

2013

Alili L, Sack M, von Montfort C, Giri S, Das S, Carroll KS, Zanger K, Seal S, Brenneisen P. Downregulation of tumor growth and invasion by redox-active nanoparticles. Antioxid Redox Signal. 2013 Sep 10;19(8):765-78. Epub 2013 Jan 24. doi: 10.1089/ars.2012.4831. PMID: 23198807.

2011

Alili L, Sack M, Karakoti AS, Teuber S, Puschmann K, Hirst SM, Reilly CM, Zanger K, Stahl W, Das S, Seal S, Brenneisen P. Combined cytotoxic and anti-invasive properties of redox-active nanoparticles in tumor-stroma interactions. Biomaterials. 2011 Apr;32(11):2918-29. Epub 2011 Jan 26.  doi: 10.1016/j.biomaterials.2010.12.056. PMID: 21269688.

2008

Werth C, Stuhlmann D, Cat B, Steinbrenner H, Alili L, Sies H, Brenneisen P. Stromal resistance of fibroblasts against oxidative damage: involvement of tumor cell-secreted platelet-derived growth factor (PDGF) and phosphoinositide 3-kinase (PI3K) activation. Carcinogenesis. 2008 Feb;29(2):404-10. Epub 2008 Jan 3. doi: 10.1093/carcin/bgm296. PMID: 18174235.

2007

Steinbrenner H, Alili L, Stuhlmann D, Sies H, Brenneisen P. Post-translational processing of selenoprotein P: implications of glycosylation for its utilisation by target cells. Biol Chem. 2007 Oct;388(10):1043-51. PMID: 17937618.

2006

Schneider LA, Dissemond J, Schwamborn E, Wlaschek M, Brenneisen P, Scharffetter-Kochanek K. Tirilazad amelioriates extracellular effects of photooxidative stress by sealing the membrane of UVA irradiated human dermal fibroblasts. Eur J Dermatol. 2006 Sep-Oct;16(5):530-6. PMID: 17101474.

Steinbrenner H, Bilgic E, Alili L, Sies H, Brenneisen P. Selenoprotein P protects endothelial cells from oxidative damage by stimulation of glutathione peroxidase expression and activity. Free Radic Res. 2006 Sep;40(9):936-43. PMID: 17015273.

Cat B, Stuhlmann D, Steinbrenner H, Alili L, Holtkötter O, Sies H, Brenneisen P. Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species. J Cell Sci. 2006 Jul 1;119(Pt13):2727-38. Epub 2006 Jun 6. PMID: 16757516.

Steinbrenner H, Alili L, Bilgic E, Sies H, Brenneisen P. Involvement of selenoprotein P in protection of human astrocytes from oxidative damage. Free Radic Biol Med. 2006 May 1;40(9):1513-23. Epub 2006 Jan 13. PMID: 16632112.

2005

Schneider LA, Dissemond J, Brenneisen P, Hainzl A, Briviba K, Wlaschek M, Scharffetter-Kochanek K. Adaptive cellular protection against UVA-1-induced lipid peroxidation in human dermal fibroblasts shows donor-to-donor variability and is glutathione dependent. Arch Dermatol Res. 2006 Jan;297(7):324-8. Epub 2005 Nov 18. PMID: 16328346.

Brenneisen P, Steinbrenner H, Sies H. Selenium, oxidative stress, and health aspects. Mol Aspects Med. 2005 Aug-Oct;26(4-5):256-67. Review. PMID: 16105679.

Steinbrenner H, Ramos MC, Stuhlmann D, Mitic D, Sies H, Brenneisen P. Tumor promoter TPA stimulates MMP-9 secretion from human keratinocytes by activation of superoxide-producing NADPH oxidase. Free Radic Res. 2005 Mar;39(3):245-53. PMID: 15788229.

Schroeder P, Voevodskaya N, Klotz LO, Brenneisen P, Gräslund A, Sies H. Loss of the tyrosyl radical in mouse ribonucleotide reductase by (-)-epicatechin. Biochem Biophys Res Commun. 2005 Jan 21;326(3):614-7. PMID: 15596143.

2004

Wenk J, Schüller J, Hinrichs C, Syrovets T, Azoitei N, Podda M, Wlaschek M, Brenneisen P, Schneider LA, Sabiwalsky A, Peters T, Sulyok S, Dissemond J, Schauen M, Krieg T, Wirth T, Simmet T, Scharffetter-Kochanek K. Overexpression of phospholipid-hydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/matrix metalloproteinase-1 by suppression of phosphatidylcholine hydroperoxide-mediated NFkappaB activation and interleukin-6 release. J Biol Chem. 2004 Oct 29;279(44):45634-42. Epub 2004 Aug 10. PMID: 15308634.

Stuhlmann D, Steinbrenner H, Wendlandt B, Mitic D, Sies H, Brenneisen P. Paracrine effect of TGF-beta1 on downregulation of gap junctional intercellular communication between human dermal fibroblasts. Biochem Biophys Res Commun. 2004 Jun 25;319(2):321-6. PMID: 15178409.

Ramos MC, Steinbrenner H, Stuhlmann D, Sies H, Brenneisen P. Induction of MMP-10 and MMP-1 in a squamous cell carcinoma cell line by ultraviolet radiation. Biol Chem. 2004 Jan;385(1):75-86. PMID: 14977049.

Oh JH, Chung AS, Steinbrenner H, Sies H, Brenneisen P. Thioredoxin secreted upon ultraviolet A irradiation modulates activities of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in human dermal fibroblasts. Arch Biochem Biophys. 2004 Mar 1;423(1):218-26. PMID: 14871484.

2003

Ma W, Hommel C, Brenneisen P, Peters T, Smit N, Sedivy J, Scharffetter-Kochanek K, Wlaschek M. Long-term growth arrest of PUVA-treated fibroblasts in G2/M in the absence of p16(INK4a) p21(CIP1) or p53. Exp Dermatol. 2003 Oct;12(5):629-37. PMID: 14705804.

Stuhlmann D, Ale-Agha N, Reinehr R, Steinbrenner H, Ramos MC, Sies H, Brenneisen P. Modulation of homologous gap junctional intercellular communication of human dermal fibroblasts via a paracrine factor(s) generated by squamous tumor cells. Carcinogenesis. 2003 Nov;24(11):1737-48. Epub 2003 Aug 29. PMID: 12949050.

Dissemond J, Schneider LA, Brenneisen P, Briviba K, Wenk J, Wlaschek M, Scharffetter-Kochanek K. Protective and determining factors for the overall lipid peroxidation in ultraviolet A1-irradiated fibroblasts: in vitro and in vivo investigations. Br J Dermatol. 2003 Aug;149(2):341-9. PMID: 12932241.

Steinbrenner H, Ramos MC, Stuhlmann D, Sies H, Brenneisen P. UVA-mediated downregulation of MMP-2 and MMP-9 in human epidermal keratinocytes. Biochem Biophys Res Commun. 2003 Aug 29;308(3):486-91. PMID: 12914776.

Brenneisen P, Blaudschun R, Gille J, Schneider L, Hinrichs R, Wlaschek M, Eming S, Scharffetter-Kochanek K. Essential role of an activator protein-2 (AP-2)/specificity protein 1 (Sp1) cluster in the UVB-mediated induction of the human vascular endothelial growth factor in HaCaT keratinocytes. Biochem J. 2003 Jan 15;369(Pt 2):341-9. PubMed PMID: 12358602.

2002

Brenneisen P, Sies H, Scharffetter-Kochanek K. Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events. Ann N Y Acad Sci. 2002 Nov;973:31-43. Review. PMID: 12485830.

Naderi-Hachtroudi L, Peters T, Brenneisen P, Meewes C, Hommel C, Razi-Wolf Z, Schneider LA, Schüller J, Wlaschek M, Scharffetter-Kochanek K. Induction of manganese superoxide dismutase in human dermal fibroblasts: a UV-B-mediated paracrine mechanism with the release of epidermal interleukin 1 alpha, interleukin 1 beta, and tumor necrosis factor alpha. Arch Dermatol. 2002 Nov;138(11):1473-9. PMID: 12437453.

Dissemond J, Schneider LA, Brenneisen P, Peters T, Wlaschek M, Klein P, Hinrichs R, Scharffetter- Kochanek K. Beta 2 integrin-mediated adherence does not modulate superoxide anion release from neutrophils and subsequent lipid peroxidation of surrounding fibroblasts. Br J Dermatol. 2002 Aug;147(2):401-3. PMID: 12174134.

Brenneisen P, Wlaschek M, Schwamborn E, Schneider LA, Ma W, Sies H, Scharffetter-Kochanek K. Activation of protein kinase CK2 is an early step in the ultraviolet B-mediated increase in interstitial collagenase (matrix
metalloproteinase-1; MMP-1) and stromelysin-1 (MMP-3) protein levels in human dermal fibroblasts. Biochem J. 2002 Jul 1;365(Pt 1):31-40. PubMed PMID: 12071839.

Blaudschun R, Sunderkötter C, Brenneisen P, Hinrichs R, Peters T, Schneider L, Razi-Wolf Z, Hunzelmann N, Scharffetter-Kochanek K. Vascular endothelial growth factor causally contributes to the angiogenic response upon ultraviolet B irradiation in vivo. Br J Dermatol. 2002 Apr;146(4):581-7. PMID: 11966687.

Ma W, Wlaschek M, Brenneisen P, Schneider LA, Hommel C, Hellweg C, Sauer H, Wartenberg M, Herrmann G, Meewes C, Boukamp P, Scharffetter-Kochanek K. Human dermal fibroblasts escape from the long-term phenocopy of senescence induced by psoralen photoactivation. Exp Cell Res. 2002 Apr 1;274(2):299-309. PMID: 11900490.

2001

Hunzelmann N, Nischt R, Brenneisen P, Eickert A, Krieg T. Increased deposition of fibulin-2 in solar elastosis and its colocalization with elastic fibres. Br J Dermatol. 2001 Aug;145(2):217-22. PMID: 11531782.

Wenk J, Foitzik A, Achterberg V, Sabiwalsky A, Dissemond J, Meewes C, Reitz A, Brenneisen P, Wlaschek M, Meyer-Ingold W, Scharffetter-Kochanek K. Selective pick-up of increased iron by deferoxamine-coupled cellulose abrogates the iron-driven induction of matrix-degrading metalloproteinase 1 and lipid peroxidation in human dermal fibroblasts in vitro: a new dressing concept. J Invest Dermatol. 2001 Jun;116(6):833-9.  PMID: 11407968.

Wenk J, Brenneisen P, Meewes C, Wlaschek M, Peters T, Blaudschun R, Ma W, Kuhr L, Schneider L, Scharffetter-Kochanek K. UV-induced oxidative stress and photoaging. Curr Probl Dermatol. 2001;29:83-94. Review. PMID: 11225204.

Meewes C, Brenneisen P, Wenk J, Kuhr L, Ma W, Alikoski J, Poswig A, Krieg T, Scharffetter-Kochanek K. Adaptive antioxidant response protects dermal fibroblasts from UVA-induced phototoxicity. Free Radic Biol Med. 2001 Feb 1;30(3):238-47. PMID: 11165870.

2000

Wlaschek M, Hommel C, Wenk J, Brenneisen P, Ma W, Herrmann G, Scharffetter-Kochanek K. Isolation and identification of psoralen plus ultraviolet A (PUVA)-induced genes in human dermal fibroblasts by polymerase chain reaction-based subtractive hybridization. J Invest Dermatol. 2000 Nov;115(5):909-13. PMID: 11069632.

Wlaschek M, Wenk J, Brenneisen P, Hommel C, Ma W, Herrmann G, Scharffetter-Kochanek K. PCR-based subtractive hybridization identifies repressed genes in growth-arrested human dermal fibroblasts following combined treatment with 8-methoxypsoralen and UVA irradiation (PUVA). Exp Gerontol. 2000 Aug;35(5):573-81. PMID: 10978679.

Poswig A, Hinrichs R, Megahed M, Hunzelmann N, Kirchberg K, Brenneisen P, Krieg T, Scharffetter-Kochanek K. Discrete papular mucinosis-a rare subtype of lichen myxoedematosus. Clin Exp Dermatol. 2000 Jun;25(4):289-92. PMID: 10971487.

Meewes C, Poswig A, Dissemond J, Brenneisen P, Scharffetter-Kochanek K. Adaptive antioxidant defence in human dermal fibroblasts. Br J Dermatol. 2000 Sep;143(3):662-3. PMID: 10971359.

Neess CM, Hinrichs R, Dissemond J, Herrmann G, Poswig A, Servera-Llanras M, Hunzelmann N, Brenneisen P, Meewes C, Krieg T, Scharffetter-Kochanek K. Treatment of pruritus by capsaicin in a patient with pityriasis rubra pilaris receiving RE-PUVA therapy. Clin Exp Dermatol. 2000 May;25(3):209-11. PMID: 10844497.

Blaudschun R, Brenneisen P, Wlaschek M, Meewes C, Scharffetter-Kochanek K. The first peak of the UVB irradiation-dependent biphasic induction of vascular endothelial growth factor (VEGF) is due to phosphorylation of the epidermal growth factor receptor and independent of autocrine transforming growth factor alpha. FEBS Lett. 2000 Jun 2;474(2-3):195-200. PMID: 10838084.

Scharffetter-Kochanek K, Brenneisen P, Wenk J, Herrmann G, Ma W, Kuhr L, Meewes C, Wlaschek M. Photoaging of the skin from phenotype to mechanisms. Exp Gerontol. 2000 May;35(3):307-16. Review. PMID: 10832052.

Brenneisen P, Wenk J, Wlaschek M, Krieg T, Scharffetter-Kochanek K. Activation of p70 ribosomal protein S6 kinase is an essential step in the DNA damage-dependent signaling pathway responsible for the ultraviolet B-mediated increase in interstitial collagenase (MMP-1) and stromelysin-1 (MMP-3) protein levels in human dermal fibroblasts. J Biol Chem. 2000 Feb 11;275(6):4336-44. PMID: 10660603.

1999

Hinrichs R, Kirchberg K, Dissemond J, Hoppe JD, Brenneisen P, Krieg T, Scharffetter-Kochanek K. Carcinoma erysipeloides of the facial skin in a patient with metastatic breast cancer. Br J Dermatol. 1999 Nov;141(5):940-1. PMID: 10583192.

Brenneisen P, Wenk J, Wlaschek M, Blaudschun R, Scharffetter-Kochanek K. A newly adapted pulsed-field gel electrophoresis technique allows to detect distinct types of DNA damage at low frequencies in human dermal fibroblasts upon exposure to non-toxic H2O2 concentrations. Free Radic Res. 1999 Nov;31(5):405-18. PMID: 10547185.

Wenk J, Brenneisen P, Wlaschek M, Poswig A, Briviba K, Oberley TD, Scharffetter-Kochanek K. Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major oxidant in the AP-1-mediated induction of matrix-degrading metalloprotease-1. J Biol Chem. 1999 Sep 3;274(36):25869-76. PMID: 10464329.

Brenneisen P, Wlaschek M, Wenk J, Blaudschun R, Hinrichs R, Dissemond J, Krieg T, Scharffetter-Kochanek K. Ultraviolet-B induction of interstitial collagenase and stromelyin-1 occurs in human dermal fibroblasts via an autocrine interleukin-6-dependent loop. FEBS Lett. 1999 Apr 16;449(1):36-40. PMID: 10225423.

Poswig A, Wenk J, Brenneisen P, Wlaschek M, Hommel C, Quel G, Faisst K, Dissemond J, Briviba K, Krieg T, Scharffetter-Kochanek K. Adaptive antioxidant response of manganese-superoxide dismutase following repetitive UVA irradiation. J Invest Dermatol. 1999 Jan;112(1):13-8. PMID: 9886257.

1998

Brenneisen P, Blaudschun R, Bernards M, Wenk J, Wlaschek M, Meyer-Ingold W, Schauen M, Krieg T, Scharffetter-Kochanek K. Increased temperature: a potentially important side-effect of ultraviolet radiation treatment leading to induction of interstitial collagenase/matrix metalloproteinase-1. Br J Dermatol. 1998 Sep;139(3):537-9. PMID: 9767309.

Herrmann G, Brenneisen P, Wlaschek M, Wenk J, Faisst K, Quel G, Hommel C, Goerz G, Ruzicka T, Krieg T, Sies H, Scharffetter-Kochanek K. Psoralen photoactivation promotes morphological and functional changes in fibroblasts in vitro reminiscent of cellular senescence. J Cell Sci. 1998 Mar;111 (Pt 6):759-67. PMID: 9472004.

Brenneisen P, Wenk J, Klotz LO, Wlaschek M, Briviba K, Krieg T, Sies H, Scharffetter-Kochanek K. Central role of Ferrous/Ferric iron in the ultraviolet B irradiation-mediated signaling pathway leading to increased interstitial collagenase (matrix-degrading metalloprotease (MMP)-1) and stromelysin-1 (MMP-3) mRNA levels in cultured human dermal fibroblasts. J Biol Chem. 1998 Feb 27;273(9):5279-87. PMID: 9478985.

1997

Scharffetter-Kochanek K, Wlaschek M, Brenneisen P, Schauen M, Blaudschun R, Wenk J. UV-induced reactive oxygen species in photocarcinogenesis and photoaging. Biol Chem. 1997 Nov;378(11):1247-57. Review. PMID: 9426184.

Wlaschek M, Wenk J, Brenneisen P, Briviba K, Schwarz A, Sies H, Scharffetter-Kochanek K. Singlet oxygen is an early intermediate in cytokine-dependent ultraviolet-A induction of interstitial collagenase in human
dermal fibroblasts in vitro. FEBS Lett. 1997 Aug 18;413(2):239-42. PMID: 9280289.

Brenneisen P, Briviba K, Wlaschek M, Wenk J, Scharffetter-Kochanek K. Hydrogen peroxide (H2O2) increases the steady-state mRNA levels of collagenase/MMP-1 in human dermal fibroblasts. Free Radic Biol Med. 1997;22(3):515-24. PMID: 8981044.

1996

Brenneisen P, Oh J, Wlaschek M, Wenk J, Briviba K, Hommel C, Herrmann G, Sies H, Scharffetter-Kochanek K. Ultraviolet B wavelength dependence for the regulation of two major matrix-metalloproteinases and their inhibitor TIMP-1 in human dermal fibroblasts. Photochem Photobiol. 1996 Nov;64(5):877-85. PMID: 8931389.

Brenneisen P, Oh J, Wlaschek M, Wenk J, Briviba K, Hommel C, Herrmann G, Sies H, Scharffetter-Kochanek K. Ultraviolet B wavelength dependence for the regulation of two major matrix-metalloproteinases and their inhibitor TIMP-1 in human dermal fibroblasts. Photochem Photobiol. 1996 Oct;64(4):649-57. Corrected and republished in: Photochem Photobiol. 1996 Nov;64(5):877-85. PMID: 8863471.

1995

Kiss M, Wlaschek M, Brenneisen P, Michel G, Hommel C, Lange TS, Peus D, Kemeny L, Dobozy A, Scharffetter-Kochanek K, et al. Alpha-melanocyte stimulating hormone induces collagenase/matrix metalloproteinase-1 in human dermal fibroblasts. Biol Chem Hoppe Seyler. 1995 Jul;376(7):425-30. PMID: 7576239.

1994

Brenneisen P, Gogol J, Bayreuther K. DNA synthesis and Fos and Jun protein expression in mitotic and postmitotic WI-38 fibroblasts in vitro. Exp Cell Res. 1994 Apr;211(2):219-30. PMID: 7908266.

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