Publications 2023

Vaccine-induced SARS-CoV-2 antibody response: the comparability of S1-specific binding assays depends on epitope and isotype discrimination.
Schest S, Langer C, Stiegler Y, Karnuth B, Arends J, Stiegler H, Masetto T, Peter C, Grimmler M. Front Immunol. 2023 Oct 26;14:1257265. doi: 10.3389/fimmu.2023.1257265. eCollection 2023. PMID: 37965324

Comprehensive Comparison of the Capacity of Functionalized Sepharose, Magnetic Core, and Polystyrene Nanoparticles to Immuno-Precipitate Procalcitonin from Human Material for the Subsequent Quantification by LC-MS/MS.
Masetto T, Matzenbach K, Reuschel T, Tölke SA, Schneider K, Esser LM, Reinhart M, Bindila L, Peter C, Grimmler M. Int J Mol Sci. 2023 Jun 30;24(13):10963. doi: 10.3390/ijms241310963. PMID: 37446139

Characterization of Native COMPASS Complex in Urothelial Carcinoma Cells by Size Exclusion Chromatography.
Peter C, Schulz WA, Whongsiri P. Methods Mol Biol. 2023;2684:101-109. doi: 10.1007/978-1-0716-3291-8_5. PMID: 37410229

Phosphorylation of pICln by the autophagy activating kinase ULK1 regulates snRNP biogenesis and splice activity of the cell.
Esser LM, Schmitz K, Hillebrand F, Erkelenz S, Schaal H, Stork B, Grimmler M, Wesselborg S, Peter C. Comput Struct Biotechnol J. 2023 Mar 16;21:2100-2109. doi: 10.1016/j.csbj.2023.03.015. eCollection 2023. PMID: 36968021 Free PMC article.

Bioinformatical Design and Performance Evaluation of a Nucleocapsid- and an RBD-Based Particle Enhanced Turbidimetric Immunoassay (PETIA) to Quantify the Wild Type and Variants of Concern-Derived Immunoreactivity of SARS-CoV-2.
Wey L, Masetto T, Spaeth A, Brehm J, Kochem C, Reinhart M, Müller H, Kempin U, Lorenz F, Peter C, Grimmler M. Biomedicines. 2023 Jan 8;11(1):160. doi: 10.3390/biomedicines11010160.PMID: 36672668 

Publications 2022

Cardiac injection of USSC boosts remuscularization of the infarcted heart by shaping the T-cell response.
Ding Z, Tan K, Alter C, Temme S, Bouvain P, Owenier C, Hänsch S, Wesselborg S, Peter C, Weidtkamp-Peters S, Flögel U, Schira-Heinen J, Stühler K, Hesse J, Kögler G, Schrader J. J Mol Cell Cardiol. 2022 Dec 6:S0022-2828(22)00566-1. doi: 10.1016/j.yjmcc.2022.11.006. 

Development of Macrocyclic PRMT5-Adaptor Protein Interaction Inhibitors.
Krzyzanowski A, Esser LM, Willaume A, Prudent R, Peter C, 't Hart P, Waldmann H. J Med Chem. 2022 Nov 15. doi: 10.1021/acs.jmedchem.2c01273. Online ahead of print.PMID: 36378254

SARS-CoV-2 antibody progression and neutralizing potential in mild symptomatic COVID-19 patients - a comparative long term post-infection study.
Brehm J, Spaeth A, Dreßler L, Masetto T, Dannenberg R, Peter C, Grimmler M. Front Immunol. 2022 Aug 17;13:915338. doi: 10.3389/fimmu.2022.915338. eCollection 2022

NF90/NFAR (nuclear factors associated with dsRNA) - a new methylation substrate of the PRMT5-WD45-RioK1 complex.
Cox J, Esser LM, Jüdt M, Schmitz K, Reiffert K, Grimmler M, Stork B, Wesselborg S, Peter C. Biol Chem. 2022 Aug 31. doi: 10.1515/hsz-2022-0136. Online ahead of print.PMID: 36040368

National External Quality Assessment and direct method comparison reflect crucial deviations of Procalcitonin measurements in Germany.
Masetto T, Eidizadeh A, Peter C, Grimmler M. Clin Chim Acta. 2022 Feb 12:S0009-8981(22)00057-2. doi: 10.1016/j.cca.2022.02.007. Online ahead of print. PMID: 35167843

Publication 2021

Characterization of the Diagnostic Performance of a Novel COVID-19 PETIA in Comparison to Four Routine N-, S- and RBD-Antigen Based Immunoassays.
Spaeth A, Masetto Th, Brehm J, Wey L, Kochem Ch, Brehm M, Peter C  and Grimmler M. Diagnostics. 2021, 11(8). doi.org/10.3390/diagnostics11081332

TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy.
Wu W, Wang X, Sun Y, Berleth N, Deitersen J, Schlütermann D, Stuhldreier F, Wallot-Hieke N, José Mendiburo M, Cox J, Peter C, Bergmann AK, Stork B. Autophagy. 2021 Dec;17(12):3992-4009. doi: 10.1080/15548627.2021.1899667. Epub 2021 Mar 28. PMID: 33779513

FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates.
Schlütermann D, Berleth N, Deitersen J, Wallot-Hieke N, Friesen O, Wu W, Stuhldreier F, Sun Y, Berning L, Friedrich A, Mendiburo MJ, Peter C, Wiek C, Hanenberg H, Stefanski A, Stühler K, Stork B.Sci Rep. 2021 Jul 5;11(1):13863. doi: 10.1038/s41598-021-92408-4. PMID: 34226595

An essential role of the autophagy activating kinase ULK1 in snRNP biogenesis.
Schmitz K, Cox J, Esser LM, Voss M, Sander K, Löffler A, Hillebrand F, Erkelenz S, Schaal H, Kähne T, Klinker S, Zhang T, Nagel-Steger L, Willbold D, Seggewiß S, Schlütermann D, Stork B, Grimmler M, Wesselborg S, Peter C. Nucleic Acids Res. 2021 Jun 21;49(11):6437-6455. doi: 10.1093/nar/gkab452. PMID: 34096600

Publication 2020

The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death.
Wu W, Wang X, Berleth N, Deitersen J, Wallot-Hieke N, Böhler P, Schlütermann D, Stuhldreier F, Cox J, Schmitz K, Seggewiß S, Peter C, Kasof G, Stefanski A, Stühler K, Tschapek A, Gödecke A, Stork B.Cell Rep. 2020 Apr 21;31(3):107547. doi: 10.1016/j.celrep.2020.107547. PMID: 32320653

Publications 2018

Targeting urothelial carcinoma cells by combining cisplatin with a specific inhibitor of the autophagy-inducing class III PtdIns3K complex.
Schlütermann D, Skowron MA, Berleth N, Böhler P, Deitersen J, Stuhldreier F, Wallot-Hieke N, Wu W, Peter C, Hoffmann MJ, Niegisch G, Stork B. Urol Oncol. 2018 Apr;36(4):160.e1-160.e13. doi: 10.1016/j.urolonc.2017.11.021. Epub 2017 Dec 21. PMID: 29276062

Systematic analysis of ATG13 domain requirements for autophagy induction.
Wallot-Hieke N, Verma N, Schlütermann D, Berleth N, Deitersen J, Böhler P, Stuhldreier F, Wu W, Seggewiß S, Peter C, Gohlke H, Mizushima N, Stork B. Autophagy. 2018;14(5):743-763. doi: 10.1080/15548627.2017.1387342. Epub 2018 Mar 21. PMID: 29173006

Publications 2017

Serum α-1 Antitrypsin (AAT) antagonizes intrinsic apoptosis induction in neutrophils from patients with systemic inflammatory response syndrome.
Sarabhai T, Peter C, Bär AK, Windolf J, Relja B, Wesselborg S, Wahlers T, Paunel-Görgülü A. PLoS One. 2017 May 11;12(5):e0177450. doi: 10.1371/journal.pone.0177450. eCollection 2017. PMID: 28493974

Publications 2016

Staurosporine resistance in inflammatory neutrophils is associated with the inhibition of caspase- and proteasome-mediated Mcl-1 degradation.
Hornstein T, Lehmann S, Philipp D, Detmer S, Hoffmann M, Peter C, Wesselborg S, Unfried K, Windolf J, Flohé S, Paunel-Görgülü A. J Leukoc Biol. 2016 Jan;99(1):163-74. doi: 10.1189/jlb.3A1114-537RR. Epub 2015 Aug 26. PMID: 26310832

Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells.
Hieke N, Löffler AS, Kaizuka T, Berleth N, Böhler P, Drießen S, Stuhldreier F, Friesen O, Assani K, Schmitz K, Peter C, Diedrich B, Dengjel J, Holland P, Simonsen A, Wesselborg S, Mizushima N, Stork B. Autophagy. 2015;11(9):1471-83. doi: 10.1080/15548627.2015.1068488. PMID: 26213203

Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy.
Drießen S, Berleth N, Friesen O, Löffler AS, Böhler P, Hieke N, Stuhldreier F, Peter C, Schink KO, Schultz SW, Stenmark H, Holland P, Simonsen A, Wesselborg S, Stork B. Autophagy. 2015;11(9):1458-70. doi: 10.1080/15548627.2015.1067359. PMID: 26207339

Publications 2014

PDK1 controls upstream PI3K expression and PIP3 generation.
Dieterle AM, Böhler P, Keppeler H, Alers S, Berleth N, Drießen S, Hieke N, Pietkiewicz S, Löffler AS, Peter C, Gray A, Leslie NR, Shinohara H, Kurosaki T, Engelke M, Wienands J, Bonin M, Wesselborg S, Stork B. Oncogene. 2014 Jun 5;33(23):3043-53. doi: 10.1038/onc.2013.266. Epub 2013 Jul 29. PMID: 23893244

Publications 2012

Serum-derived plasminogen is activated by apoptotic cells and promotes their phagocytic clearance.
Rosenwald M, Koppe U, Keppeler H, Sauer G, Hennel R, Ernst A, Blume KE, Peter C, Herrmann M, Belka C, Schulze-Osthoff K, Wesselborg S, Lauber K. J Immunol. 2012 Dec 15;189(12):5722-8. doi: 10.4049/jimmunol.1200922. Epub 2012 Nov 12. PMID: 23150713

Release of lysophospholipid 'find-me' signals during apoptosis requires the ATP-binding cassette transporter A1.
Peter C, Waibel M, Keppeler H, Lehmann R, Xu G, Halama A, Adamski J, Schulze-Osthoff K, Wesselborg S, Lauber K. Autoimmunity. 2012 Dec;45(8):568-73. doi: 10.3109/08916934.2012.719947. Epub 2012 Sep 17. PMID: 22913458

Publications 2011

Dual antitumour effect of 5-azacytidine by inducing a breakdown of resistance-mediating factors and epigenetic modulation.
Venturelli S, Berger A, Weiland T, Zimmermann M, Häcker S, Peter C, Wesselborg S, Königsrainer A, Weiss TS, Gregor M, Fulda S, Lauer UM, Bitzer M. Gut. 2011 Feb;60(2):156-65. doi: 10.1136/gut.2010.208041. Epub 2010 Nov 23. PMID: 21106551

RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.
Guderian G, Peter C, Wiesner J, Sickmann A, Schulze-Osthoff K, Fischer U, Grimmler M. J Biol Chem. 2011 Jan 21;286(3):1976-86. doi: 10.1074/jbc.M110.148486. Epub 2010 Nov 16. PMID: 21081503

Publications 2010

Apoptosis: opening PANdora's BoX.
Peter C, Wesselborg S, Lauber K. Curr Biol. 2010 Nov 9;20(21):R940-2. doi: 10.1016/j.cub.2010.09.066. Erratum in: Curr Biol. 2011 Jan 11;21(1):96. PMID: 21056838

Dangerous attraction: phagocyte recruitment and danger signals of apoptotic and necrotic cells.
Peter C, Wesselborg S, Herrmann M, Lauber K. Apoptosis. 2010 Sep;15(9):1007-28. doi: 10.1007/s10495-010-0472-1. Review. PMID: 20157780

Molecular suicide notes: last call from apoptosing cells.
Peter C, Wesselborg S, Lauber K. J Mol Cell Biol. 2010 Apr;2(2):78-80. doi: 10.1093/jmcb/mjp045. Epub 2009 Dec 11. PMID: 20008330

Publications 2009

Scent of dying cells: the role of attraction signals in the clearance of apoptotic cells and its immunological consequences.
Muñoz LE, Peter C, Herrmann M, Wesselborg S, Lauber K. Autoimmun Rev. 2010 Apr;9(6):425-30. doi: 10.1016/j.autrev.2009.11.016. Epub 2009 Nov 25. Review. PMID: 19932201

Publications 2008

Migration to apoptotic "find-me" signals is mediated via the phagocyte receptor G2A.
Peter C, Waibel M, Radu CG, Yang LV, Witte ON, Schulze-Osthoff K, Wesselborg S, Lauber K. J Biol Chem. 2008 Feb 29;283(9):5296-305. Epub 2007 Dec 18. PMID: 18089568

Publications 2005

Unrip, a factor implicated in cap-independent translation, associates with the cytosolic SMN complex and influences its intracellular localization.
Grimmler M, Otter S, Peter C, Müller F, Chari A, Fischer U. Hum Mol Genet. 2005 Oct 15;14(20):3099-111. Epub 2005 Sep 13. PMID: 16159890