Publications 2009

IkappaBzeta expression is regulated by miR-124a.

Lindenblatt C, Schulze-Osthoff K, Totzke G.

Cell Cycle. 2009 Jul 1;8(13):2019-23. Epub 2009 Jul 21. PMID: 19502795

 
Publications 2006

Caspase-10 in mouse or not?

Jänicke RU, Sohn D, Totzke G, Schulze-Osthoff K.

Science. 2006 Jun 30;312(5782):1874. No abstract available. PMID: 16809511

Friend or foe? The proteasome in combined cancer therapy.

Sohn D, Totzke G, Schulze-Osthoff K, Jänicke RU.

Cell Cycle. 2006 Apr;5(8):841-5. Epub 2006 Apr 17. Review. PMID 16628002

A novel member of the IkappaB family, human IkappaB-zeta, inhibits transactivation of p65 and its DNA binding.

Totzke G, Essmann F, Pohlmann S, Lindenblatt C, Jänicke RU, Schulze-Osthoff K.

J Biol Chem. 2006 May 5;281(18):12645-54. Epub 2006 Mar 2. PMID: 16513645

The proteasome is required for rapid initiation of death receptor-induced apoptosis.

Sohn D, Totzke G, Essmann F, Schulze-Osthoff K, Levkau B, Jänicke RU.

Mol Cell Biol. 2006 Mar;26(5):1967-78. PMID: 16479014

 
Publications 2005

Identification of p54(nrb) and the 14-3-3 Protein HS1 as TNF-alpha-inducible genes related to cell cycle control and apoptosis in human arterial endothelial cells.

Stier S, Totzke G, Gruewald E, Neuhaus T, Fronhoffs S, Schoneborn S, Vetter H, Ko Y.

J Biochem Mol Biol. 2005 Jul 31;38(4):447-56. PMID: 16053712

Caspase-10 sensitizes breast carcinoma cells to TRAIL-induced but not tumor necrosis factor-induced apoptosis in a caspase-3-dependent manner.

Engels IH, Totzke G, Fischer U, Schulze-Osthoff K, Jänicke RU.

Mol Cell Biol. 2005 Apr;25(7):2808-18. PMID: 15767684

 
Publications 2004

Apoptosis resistance of MCF-7 breast carcinoma cells to ionizing radiation is independent of p53 and cell cycle control but caused by the lack of caspase-3 and a caffeine-inhibitable event.

Essmann F, Engels IH, Totzke G, Schulze-Osthoff K, Jänicke RU.

Cancer Res. 2004 Oct 1;64(19):7065-72. PMID: 15466201

 
Publications 2003

The use of suppression subtractive hybridization for the study of SDF-1alpha induced gene-expression in human endothelial cells.

Neuhaus T, Lutz C, Stier S, Totzke G, Gruenewald E, Fronhoffs S, Sachinidis A, Vetter H, Ko YD.

Mol Cell Probes. 2003 Oct;17(5):245-52. PMID: 14580399

Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition.

Totzke G, Schulze-Osthoff K, Jänicke RU.

Oncogene. 2003 Sep 11;22(39):8021-30. PMID: 12970750

Staphylococcus aureus alpha-toxin-induced cell death: predominant necrosis despite apoptotic caspase activation.

Essmann F, Bantel H, Totzke G, Engels IH, Sinha B, Schulze-Osthoff K, Jänicke RU.

Cell Death Differ. 2003 Nov;10(11):1260-72. PMID: 12894214

Stromal cell-derived factor 1alpha (SDF-1alpha) induces gene-expression of early growth response-1 (Egr-1) and VEGF in human arterial endothelial cells and enhances VEGF induced cell proliferation.

Neuhaus T, Stier S, Totzke G, Gruenewald E, Fronhoffs S, Sachinidis A, Vetter H, Ko YD.

Cell Prolif. 2003 Apr;36(2):75-86. PMID: 12680875

 
Publications 2002

A method for the rapid construction of cRNA standard curves in quantitative real-time reverse transcription polymerase chain reaction.

Fronhoffs S, Totzke G, Stier S, Wernert N, Rothe M, Brüning T, Koch B, Sachinidis A, Vetter H, Ko Y.

Mol Cell Probes. 2002 Apr;16(2):99-110. PMID: 12030760

 
Publications 2001

Effects of antithrombin III on tumor necrosis factor-alpha and interleukin-1beta synthesis in vascular smooth muscle cells.

Totzke G, Schobersberger W, Schloesser M, Czechowski M, Hoffmann G.

J Interferon Cytokine Res. 2001 Dec;21(12):1063-9. PMID: 11798464

Effect of vitamin E and vitamin C on the DNA synthesis of human umbilical arterial endothelial cells.

Totzke G, Metzner C, Ulrich-Merzenich G, Ko Y, Sachinidis A, Vetter H.

Eur J Nutr. 2001 Jun;40(3):121-6. PMID: 11697444

P53 downregulation in myelodysplastic syndrome--a quantitative analysis by competitive RT-PCR.

Totzke G, Brüning T, Vetter H, Schulze-Osthoff K, Ko Y.

Leukemia. 2001 Oct;15(10):1663-4. No abstract available. PMID: 11587227

Antithrombin III enhances inducible nitric oxide synthase gene expression in vascular smooth muscle cells.

Totzke G, Smolny M, Seibel M, Czechowski M, Schobersberger W, Hoffmann G.

Cell Immunol. 2001 Feb 25;208(1):1-8. PMID: 11277613

In vitro modulation of inducible nitric oxide synthase gene expression and nitric oxide synthesis by procalcitonin.

Hoffmann G, Totzke G, Seibel M, Smolny M, Wiedermann FJ, Schobersberger W.

Crit Care Med. 2001 Jan;29(1):112-6. PMID: 11176169

Publications 2000

Different patterns of inducible nitric oxide synthase gene expression in ovarian carcinoma cell lines.

Rieder J, Marth C, Totzke G, Smolny M, Seibel M, Hoffmann G.

Anticancer Res. 2000 Sep-Oct;20(5A):3251-8. PMID: 11062750

High percentage of false-positive results of cytokeratin 19 RT-PCR in blood: a model for the analysis of illegitimate gene expression.

Ko Y, Grünewald E, Totzke G, Klinz M, Fronhoffs S, Gouni-Berthold I, Sachinidis A, Vetter H.

Oncology. 2000 Jun;59(1):81-8. PMID: 10895072

Differential gene expression in synovium of rheumatoid arthritis and osteoarthritis.

Jüsten HP, Grünewald E, Totzke G, Gouni-Berthold I, Sachinidis A, Wessinghage D, Vetter H, Schulze-Osthoff K, Ko Y.

Mol Cell Biol Res Commun. 2000 Mar;3(3):165-72. PMID: 10860865

Tumour necrosis factor-alpha gene expression and production in human umbilical arterial endothelial cells.

Neuhaus T, Totzke G, Gruenewald E, Juesten HP, Sachinidis A, Vetter H, Ko Y.

Clin Sci (Lond). 2000 Apr;98(4):461-70. PMID: 10731482

Identification of syntenin and other TNF-inducible genes in human umbilical arterial endothelial cells by suppression subtractive hybridization.

Stier S, Totzke G, Grünewald E, Neuhaus T, Fronhoffs S, Sachinidis A, Vetter H, Schulze-Osthoff K, Ko Y.

FEBS Lett. 2000 Feb 11;467(2-3):299-304. PMID: 10675558

Publications 1999

Cytokine-inducible growth factor gene expression in human umbilical endothelial cells.

Ko Y, Totzke G, Gouni-Berthold I, Sachinidis A, Vetter H.

Mol Cell Probes. 1999 Jun;13(3):203-11. PMID: 10369746

 
Publications 1998

Limitations of the reverse transcription-polymerase chain reaction method for the detection of carcinoembryonic antigen-positive tumor cells in peripheral blood.

Ko Y, Klinz M, Totzke G, Gouni-Berthold I, Sachinidis A, Vetter H.

Clin Cancer Res. 1998 Sep;4(9):2141-6. PMID: 9748132

 
Publications 1997

Angiotensin type-1 (AT1) receptor gene expression in primarily cultured human arterial umbilical endothelial cells.

Ko Y, Glodny B, Stier S, Totzke G, Nickenig G, Düsing R, Sachinidis A, Vetter H.

Biochem Pharmacol. 1997 Feb 7;53(3):417-21. PMID: 9065746

Cell-cycle arrest in G0/G1 phase of growth factor-induced endothelial cell proliferation by various calcium channel blockers.

Zeitler H, Ko Y, Glodny B, Totzke G, Appenheimer M, Sachinidis A, Vetter H.

Cancer Detect Prev. 1997;21(4):332-9. PMID: 9232324

 
Publications 1996

Competitive reverse transcription/polymerase chain reaction for the quantification of p53 and mdm2 mRNA expression.

Totzke G, Sachinidis A, Vetter H, Ko Y.

Mol Cell Probes. 1996 Dec;10(6):427-33. PMID: 9025080

 
Publication 1995

Native low-density lipoprotein (LDL) induces the expression of the early growth response gene-1 in human umbilical arterial endothelial cells.

Ko Y, Totzke G, Seewald S, Schmitz U, Schiermeyer B, Meyer zu Brickwedde MK, Vetter H, Sachinidis A.

Eur J Cell Biol. 1995 Nov;68(3):306-12. PMID: 8603683

Reverse transcriptase-polymerase chain reaction (RT-PCR): a sensitive method to examine basic fibroblast growth factor-induced expression of the early growth response gene-1 (egr-1) in human umbilical arterial endothelial cells.

Ko Y, Totzke G, Schiermeyer B, Zeitler H, Schmitz U, Vetter H, Sachinidis A.

Mol Cell Probes. 1995 Aug;9(4):215-22. PMID: 7477016

 
Publications 1993

Lipoprotein-induced expression of the sis oncogene in human arterial endothelial cells.

Ko Y, Totzke G, Schulte K, Schiermeyer B, Meyer zu Brickwedde MK, Vetter H, Sachinidis A.

J Hypertens Suppl. 1993 Dec;11(5):S132-3. No abstract available. PMID: 8158311

Action of dihydropyridine calcium antagonists on early growth response gene expression and cell growth in vascular smooth muscle cells.

Ko Y, Totzke G, Graack GH, Heidgen FJ, Meyer zu Brickwedde MK, Düsing R, Vetter H, Sachinidis A.

J Hypertens. 1993 Nov;11(11):1171-8. PMID: 8301097