Hepatoimmunology Group
Research
Elucidation of intra- and intercellular signaling networks involved in:
- regulation of the systemic acute-phase response
- mediating liver damage and orchestrating regeneration
- influencing the activation state of macrophage populations in the liver
- promoting metabolic liver disease and its progression to fibrosis and liver cancer
- establishment of persistent viral infections
Funding
- Manchot foundation: “Interference of HCV with host intercellular communication processes mediated by inflammatory mediators”, Manchot graduate school: Molecules of infection (MOI) IV, 2020-2024
- BMBF: “Mechanism-based multiscale model for dissection of the tipping point from liver cirrhosis to hepatocellular carcinoma”, Liver Systems Medicine against Cancer (LiSyM Cancer), 2021-2024
- DFG: “Virus-induced changes in cellular signaling in hepatocytes lead to reprogramming of the cell's response to growth factors – analysis of molecular mechanisms and functional consequences”, 2023-2025
