Tissue Engineering_3D Bioprinting Research
3D bioprinting is revolutionizing tissue engineering by enabling the precise fabrication of complex, functional tissues from living cells. This groundbreaking technology is driving advancements in regenerative medicine, offering innovative solutions for organ shortages, disease modeling, and personalized treatments. These innovations are just the beginning. Ongoing research aims to enhance cell viability, material properties, and scalability, positioning 3D bioprinting as a transformative tool for personalized tissue replacements and advanced therapies. By using bioinks composed of living cells and biomaterials, our group focuses on replicating the structure and function of native tissues through advanced 3D bioprinting techniques.
Our interdisciplinary work focuses on biomaterial and bioreactor fabrication, organ-on-a-chip systems, and advanced bioprinting techniques like Fused Deposition Modeling (FDM) and Digital Light Processing (DLP). We employ knowledge of basic science, engineering, and medicine to shape the future of healthcare, offering hope to patients in need of life-changing treatments.
Key projects in our research group include:
- Bioprinting immune-competent adipose tissue-derived organoids (adipoids)
- Developing DLP-printable bioinks from natural polymers
- Engineering 3D-bioprinted cardiac patches
- Designing bioreactor systems for cardiac tissue maturation
Selected Publications
YJ Lee, O Ajiteru, JS Lee, OJ Lee, KY Choi, SH Kim, CH Park. Highly conductive, stretchable, and biocompatible graphene oxide biocomposite hydrogel for advanced tissue engineering. Biofabrication, 2024.
KY Choi, O Ajiteru, H Hong, YJ Suh, MT Sultan, H Lee, JS Lee, YJ Lee, OJ Lee, SH, Kim, CH Park. A digital light processing 3D-printed artificial skin model and full-thickness wound models using silk fibroin bioink. Acta Biomaterialia, 2023.
O Ajiteru, OJ Lee, JH Kim, YJ Lee, JS Lee, H Lee, MT Sultan, CH Park. Fabrication and characterization of a myrrh hydrocolloid dressing for dermal wound healing. Colloid and Interface Science Communications, 2022.
YJ Lee, JS Lee, O Ajiteru, OJ Lee, JS Lee, H Lee, SW Kim, JW Park, KY Kim, KY Choi, MT Sultan, SH Kim, CH Park. Biocompatible fluorescent silk fibroin bioink for digital light processing 3D printing. International Journal of Biological Macromolecules, 2022.
O Ajiteru, OJ Lee, JH Kim, YJ Lee, JS Lee, H Lee, MT Sultan, CH Park. Fabrication and characterization of a myrrh hydrocolloid dressing for dermal wound healing. Colloid and Interface Science Communications, 2022.
SH Kim, H Hong, O Ajiteru, MT Sultan, YJ Lee, JS Lee, OJ Lee, YJ Suh, H Lee, HS Park, KY Choi, JS Lee, and CH Park. 3D bioprinted silk fibroin hydrogels for tissue engineering, Nature Protocols, 2021.
O Ajiteru, KY Choi, TH Lim, DY Kim, H Hong, YJ Lee, JS Lee, H Lee, YJ Suh, MT Sultan, OJ Lee, SH Kim, and CH Park. A digital light processing 3D printed magnetic bioreactor system using silk magnetic bioink. Biofabrication, 2021.
O Ajiteru, MT Sultan, YJ Lee, YB Seo, H Hong, JS Lee, H Lee, YJ Suh, HW Ju, OJ Lee, S Park, M Jang, SH Kim, CH Park. A 3D printable electroconductive biocomposite bioink based on silk fibroin-conjugated graphene oxide. Nano letters, 2020.
MT Sultan, BY Choi, O Ajiteru, DK Hong, SM Lee, HJ Kim, JS Ryu, JS Lee, H Hong, YJ Lee, H Lee, YJ Suh, OJ Lee, SH Kim, SW Suh, CH Park. Reinforced-hydrogel encapsulated hMSCs towards brain injury treatment by trans-septal approach. Biomaterials, 2020.