Institut für Pathologie - Publikationen 2016

Swarts DR, Rudelius M, Claessen SM, Cleutjens JP, Seidl S, Volante M, Ramaekers FC, Speel EJ.
Limited additive value of Ki-67 proliferative index on patient survival
in WHO classified pulmonary carcinoids

Histopathology. 2016 Oct 4. doi: 10.1111/his.13096. [Epub ahead of print]
Hilal Z1, Rezniczek GA, Tettenborn Z, Hefler LA, Tempfer CB.
Efficacy of Monsel Solution After Cervical Biopsy: A Randomized Trial
J Low Genit Tract Dis. 2016 Oct;20(4):312-6. doi: 10.1097/LGT.0000000000000234.
Kong B, Bruns P, Behler NA, Chang L, Schlitter AM, Cao J, Gewies A, Ruland J, Fritzsche S, Valkovskaya N, Jian Z, Regel I, Raulefs S, Irmler M, Beckers J, Friess H, Erkan M, Mueller NS, Roth S, Hackert T, Esposito I, Theis FJ, Kleeff J, Michalski CW.
Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy
Gut. 2016 Sep 19. pii: gutjnl-2015-310913. doi: 10.1136/gutjnl-2015-310913. [Epub ahead of print]
Stevens J, Carosati E, Randazzo GM, Mannhold R, Mahotka C
LBPS03, a novel apoptosis inducer, overcomes a XIAP-mediated resistance by reactivation of caspases in the multidrug-resistant RCC cell line ClearCa-2
ONCOLOGY RESEARCH AND TREATMENT. 2016; 39(1):68-68
van den Höfel N, Carosati E, Randazzo M, Witt JM, Mannhold R, Mahotka C
LBPS01, a novel small-molecule, acts as a tumor specific apoptosis inducer in the ALL cell line Jurkat
ONCOLOGY RESEARCH AND TREATMENT. 2016; 39:68-68
Heid I, Steiger K, Trajkovic-Arsic M, Settles M, Eßwein MR, Erkan M, Kleeff J, Jäger C, Friess H, Haller B, Steingötter A, Schmid RM, Schwaiger M, Rummeny EJ, Esposito I, Siveke JT, Braren R.
Co-clinical assessment of tumor cellularity in pancreatic cancer
Clin Cancer Res. 2016 Sep 23. pii: clincanres.2432.2015. [Epub ahead of print]
Schwarzenböck SM, Knieling A, Souvatzoglou M, Kurth J, Steiger K, Eiber M, Esposito I, Retz M, Kübler H, Gschwend JE, Schwaiger M, Krause BJ, Thalgott M.
[11C]Choline PET/CT in therapy response assessment of a neoadjuvant therapy in locally advanced and high risk prostate cancer before radical prostatectomy
Oncotarget. 2016 Aug 27. doi: 10.18632/oncotarget.11653. [Epub ahead of print]
Wu Y, Tedesco L, Lucia K, Schlitter AM, Garcia JM, Esposito I, Auernhammer CJ, Theodoropoulou M, Arzt E, Renner U, Stalla GK.
RSUME is implicated in tumorigenesis and metastasis of pancreatic
neuroendocrine tumors

Oncotarget. 2016 Aug 5. doi: 10.18632/oncotarget.11081. [Epub ahead of print]
Vahadane A, Peng T, Sethi A, Albarqouni S, Wang L, Baust M, Steiger K, Schlitter AM, Esposito I, Navab N.
Structure-Preserving Color Normalization and Sparse Stain Separation
for Histological Images

IEEE Trans Med Imaging. 2016 Aug;35(8):1962-71. doi: 10.1109/TMI.2016.2529665. Epub 2016 Apr 27.
Chiblak S, Steinbauer B, Pohl-Arnold A, Kucher D, Abdollahi A, Schwager C, Höft B, Esposito I, Müller-Decker K.
K-Ras and cyclooxygenase-2 coactivation augments intraductal papillary mucinous neoplasm and Notch1 mimicking human pancreas lesions
Sci Rep. 2016 Jul 6;6:29455. doi: 10.1038/srep29455.
Ballázs C, Akhyari P, Mehdiani A, Kamiya H, Reinecke P, Felsberg J, Saeed D,
Lichtenberg A, Boeken U.
Septic-Metastasizing Aspergillus-Encephalitis Mimicking Massive Cerebral Infarction in a Heart Transplant Recipient: A Case Report
Exp Clin Transplant. 2016 Jun;14(3):349-52. doi: 10.6002/ect.2014.0115. Epub 2014 Dec 4.
Potratz J, Tillmanns A, Berning P, Korsching E, Schaefer C, Lechtape B, Schleithoff C, Unland R, Schäfer KL, Müller-Tidow C, Jürgens H, Dirksen U.
Receptor tyrosine kinase gene expression profiles of Ewing sarcomas reveal ROR1 as a potential therapeutic target in metastatic disease
Mol Oncol. 2016 May;10(5):677-92. doi: 10.1016/j.molonc.2015.12.009. Epub 2015 Dec 20.
Sorg UR, Behnke K, Degrandi D, Reich M, Keitel V, Herebian D, Deenen R, Beyer M, Schultze JL, Kohrer K, Gabbert HE, Mayatepek E, Haussinger D, Pfeffer K
Cooperative role of lymphotoxin beta receptor and tumor necrosis factor receptor p55 in murine liver regeneration
JOURNAL OF HEPATOLOGY. 2016 May; 64(2):1108-1117
Radujkovic A, Dietrich S, Andrulis M, Benner A, Longerich T, Pellagatti A, Nanda K, Giese T, Germing U, Baldus S, Boultwood J, Ho AD, Dreger P, Luft T.
Expression of CDKN1C in the bone marrow of patients with myelodysplastic syndrome and secondary acute myeloid leukemia is associated with poor survival after conventional chemotherapy
Int J Cancer. 2016 May 11. doi: 10.1002/ijc.30181. [Epub ahead of print]
Gürlevik E, Fleischmann-Mundt B, Brooks J, Demir IE, Steiger K, Ribback S, Yevsa T, Woller N, Kloos A, Ostroumov D, Armbrecht N, Manns MP, Dombrowski F, Saborowski M, Kleine M6, Wirth TC, Oettle H, Ceyhan GO, Esposito I, Calvisi DF, Kubicka S, Kühnel F.
Administration of Gemcitabine after Pancreatic Tumor Resection in Mice Induces an Anti-tumor Immune Response Mediated by Natural Killer Cells
Gastroenterology. 2016 May 19. pii: S0016-5085(16)34446-8. doi: 10.1053/j.gastro.2016.05.004. [Epub ahead of print]
Kolf AK, Hesper T, Schleich C, Hosalkar HS, Jankowiak S, Cacchi C, Antoch G, Zilkens C, Krauspe R, Bittersohl B.
T2* mapping of ovine intervertebral discs: Normative data for cervical and lumbar spine
J Orthop Res. 2016 Apr;34(4):717-24. doi: 10.1002/jor.23071. Epub 2015 Oct 26.
Esposito, I
Discriminating pancreatic cystic neoplasms: histopathological and molecular features
EUROPEAN JOURNAL OF CANCER 2016 Apr;57(1):1
Florian Bönner, MD, Maximilian Spieker, MD, Sebastian Haberkorn, MD, Christoph Jacoby, PhD, Ulrich Flögel, PhD, Bernhard Schnackenburg, PhD, Patrick Horn, MD, Petra Reinecke, MD,
Mirja Neizel-Wittke, MD, Malte Kelm, MD, Ralf Westenfeld, MD
Myocardial T2 Mapping Increases Noninvasive Diagnostic Accuracy
for Biopsy-Proven Myocarditis

2016 Apr 7. pii: S1936-878X(15)00984-5.
doi: 10.1016/j.jcmg.2015.11.014. [Epub ahead of print]
http://dx.doi.org/10.1016/j.jcmg.2015.11.014
Holtmann C, Brachert M, Spaniol K, Roth M, Cacchi C, Geerling G.
Dacryolith in a lacrimal duct
Ophthalmologe. 2016 Mar;113(3):244-7. doi: 10.1007/s00347-015-0085-8.
Saalfrank A, Janssen K, Ravon M, Flisikowski K, Eser S, Steiger K, Flisikowska T, Müller-Fliedner P, Schulze É, Brönner C, Gnann A, Kappe E, Böhm B, Schade B, Certa U, Saur D, Esposito I, Kind A, Schnieke A.
A porcine model of osteosarcoma
Oncogenesis. 2016 Mar 14;5:e210. doi: 10.1038/oncsis.2016.19.
Benitz S, Regel I, Reinhard T, Popp A, Schäffer I, Raulefs S, Kong B, Esposito I, Michalski CW, Kleeff J.
Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells
Oncotarget. 2016 Mar 8;7(10):11424-33. doi: 10.18632/oncotarget.6717.
Werner TA, Tamkan-Ölcek Y, Dizdar L, Riemer JC, Wolf A, Cupisti K, Verde PE,
Knoefel WT, Krieg A.
Survivin and XIAP: two valuable biomarkers in medullary thyroid carcinoma
Br J Cancer. 2016 Feb 16;114(4):427-34. doi: 10.1038/bjc.2016.5. Epub 2016 Feb 4.
Mersch S, Riemer JC, Schlünder PM, Ghadimi MP, Ashmawy H, Möhlendick B, Topp SA, Arent T, Kröpil P, Stoecklein NH, Gabbert HE, Knoefel WT, Krieg A
Peritoneal sarcomatosis: site of origin for the establishment of an in vitro and in vivo cell line model to study therapeutic resistance in dedifferentiated liposarcoma
Tumour Biol. 2016 Feb;37(2):2341-51. doi: 10.1007/s13277-015-4050-6. Epub 2015 Sep 15.
Song L, Wörmann S, Ai J, Neuhöfer P, Lesina M, Diakopoulos KN, Ruess D, Treiber M, Witt H, Bassermann F, Halangk W, Steiner JM, Esposito I, Rosendahl J, Schmid RM, Riemann M, Algül H.
BCL3 Reduces the Sterile Inflammatory Response in Pancreatic and Biliary Tissues
Gastroenterology. 2016 Feb;150(2):499-512.e20.
doi: 10.1053/j.gastro.2015.10.017. Epub 2015 Oct 23.
Jasmin C. Riemer, Andreas Krieg, Dirk Graf, Wolfram T. Knoefel, Irene Esposito
Neuroendokrines Karzinom des Analkanals: Eine seltene Differenzialdiagnose
Gastroenterologie up2date 2016; 12(01): 16-18
DOI: 10.1055/s-0042-100860
Tóth C, Meinrath J, Herpel E, Derix J, Fries J, Buettner R, Schirmacher P, Heikaus S.
Expression of the apoptosis repressor with caspase recruitment domain (ARC) in liver metastasis of colorectal cancer and its correlation with DNA mismatch repair proteins and p53
J Cancer Res Clin Oncol. 2016 May;142(5):927-35. doi: 10.1007/s00432-015-2102-3. Epub 2015 Dec 31.
Regel I, Hausmann S, Benitz S, Esposito I, Kleeff J.
Pathobiology of pancreatic cancer: implications on therapy
Expert Rev Anticancer Ther. 2016 Feb;16(2):219-27. doi: 10.1586/14737140.2016.1129276.
Epub 2016 Jan 11.
Grüner BM, Winkelmann I, Feuchtinger A, Sun N, Balluff B, Teichmann N,
Herner A, Kalideris E, Steiger K, Braren R, Aichler M, Esposito I, Schmid RM,
Walch A, Siveke JT.
Modeling therapy response and spatial tissue distribution of erlotinib
in pancreatic cancer

Mol Cancer Ther. 2016 Jan 28. pii: molcanther.0165.2015.
Schlitter AM, Jang KT, Klöppel G, Saka B, Hong SM, Choi H, Offerhaus GJ, Hruban RH, Zen Y, Konukiewitz B, Regel I, Allgäuer M, Balci S, Basturk O, Reid MD, Esposito I, Adsay V.
Intraductal tubulopapillary neoplasms of the bile ducts: clinicopathologic, immunohistochemical, and molecular analysis of 20 cases
Mod Pathol. 2016 Jan;29(1):93. doi: 10.1038/modpathol.2015.106.
Hausmann S, Regel I, Steiger K, Wagner N, Thorwirth M, Schlitter AM, Esposito I, Michalski CW, Friess H, Kleeff J, Erkan M.
Loss of Periostin Results in Impaired Regeneration and Pancreatic Atrophy after Cerulein-Induced Pancreatitis
Am J Pathol. 2016 Jan;186(1):24-31. doi: 10.1016/j.ajpath.2015.09.022.
Epub 2015 Nov 27.

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