Witt J, Dietrich J, Mertsch S, Schrader S, Spaniol K, Geerling G. Decellularized porcine conjunctiva as an alternative substrate for tissue-engineered epithelialized conjunctiva. The Ocular Surface. 2020 Oct;18(4):901-911. doi: 10.1016/j.jtos.2020.08.009. Epub 2020 Aug 27. PMID: 32860970.

Borrelli M, Geerling G, Spaniol K, Witt J. Eye Socket Regeneration and Reconstruction. Current Eye Research. 2020 Mar;45(3):253-264. doi: 10.1080/02713683.2020.1712423. Epub 2020 Jan 10. PMID: 31910675.

Dietrich J, Schrader S. Towards Lacrimal Gland Regeneration: Current Concepts and Experimental Approaches. Current Eye Research. 2020 Mar;45(3):230-240. doi: 10.1080/02713683.2019.1637438. Epub 2019 Jul 9. PMID: 31246108.


Witt J, Borrelli M, Mertsch S, Geerling G, Spaniol K, Schrader S. Evaluation of Plastic-Compressed Collagen for Conjunctival Repair in a Rabbit Model. Tissue Engineering Part A. 2019 Aug;25(15-16):1084-1095. doi: 10.1089/ten.TEA.2018.0190. Epub 2019 Jan 30. PMID: 30501562.

Dietrich J, Ott L, Roth M, Witt J, Geerling G, Mertsch S, Schrader S. MSC Transplantation Improves Lacrimal Gland Regeneration after Surgically Induced Dry Eye Disease in Mice. Nature Scientific Reports. 2019 Dec 4;9(1):18299. doi: 10.1038/s41598-019-54840-5. PMID: 31797895; PMCID: PMC6892942.

Dietrich J, Roth M, König S, Geerling G, Mertsch S, Schrader S. Analysis of lacrimal gland derived mesenchymal stem cell secretome and its impact on epithelial cell survival. Stem Cell Res. 2019 Jul;38:101477. doi: 10.1016/j.scr.2019.101477. Epub 2019 Jun 4. PMID: 31181482.


Witt J, Mertsch S, Borrelli M, Dietrich J, Geerling G, Schrader S, Spaniol K.; Decellularised conjunctiva for ocular surface reconstruction.; Acta Biomaterialia. 2017 Dec 8. pii: S1742-7061(17)30751-1. doi: 10.1016/j.actbio.2017.11.054

Dietrich J, Schlegel C, Roth M, Witt J, Geerling G, Mertsch S, Schrader S. Comparative analysis on the dynamic of lacrimal gland damage and regeneration after Interleukin-1α or duct ligation induced dry eye disease in mice. Exp Eye Res. 2018 Jul;172:66-77. doi: 10.1016/j.exer.2018.03.026. Epub 2018 Mar 29. PMID: 29605492.

Spaniol, K., Witt, J., Mertsch, S., Borrelli, M., Geerling, G., & Schrader, S. (2018). Generation and characterisation of decellularised human corneal limbus. Graefe's Archive for Clinical and Experimental Ophthalmology, 256(3), 547-557.

Mertsch, S., Alder, J., Dua, H. S., & Geerling, G. (2018). Pathogenesis and epidemiology of neurotrophic keratopathy. Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft.

Massie, I., Spaniol, K., Barbian, A., Geerling, G., Metzger, M., & Schrader, S. (2018). Development of lacrimal gland spheroids for lacrimal gland tissue regeneration. Journal of tissue engineering and regenerative medicine, 12(4), e2001-e2009.

Schrader S, Witt J, Geerling G. Plastic compressed collagen transplantation - a new option for corneal surface reconstruction? Acta Ophthalmol. 2018 Sep;96(6):e757-e758. doi: 10.1111/aos.13649. Epub 2017 Nov 30. PMID: 29193821.


Massie I, Spaniol K, Barbian A, Poschmann G, Stühler K, Geerling G, Metzger M, Mertsch S, Schrader S., Evaluation of Decellularized Porcine Jejunum as a Matrix for Lacrimal Gland Reconstruction In Vitro for Treatment of Dry Eye Syndrome.; Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5564-5574. doi: 10.1167/iovs.16-20759

Mertsch S, Krämer OH, The interplay between histone deacetylases and rho kinases is important for cancer and neurodegeneration, Review, Cytokine Growth Factor Rev. 2017 Jun 1

Mertsch S, Thanos S, Analysis of Histone Deacetylase-Dependet Effects on Cell Migration Using the Stripe Assay, Methods Mol Biol. 2017, 1510:61-75


Massie I, Dietrich J, Roth M, Geerling G, Mertsch S, Schrader S., Development of Causative Treatment Strategies for Lacrimal Gland Insufficiency by Tissue Engineering and Cell Therapy. Part 2: Reconstruction of Lacrimal Gland Tissue: What Has Been Achieved So Far and What Are the Remaining Challenges?, Curr Eye Res. 2016 Jun 27:1-11.

Dietrich J, Massie I, Roth M, Geerling G, Mertsch S, Schrader S., Development of Causative Treatment Strategies for Lacrimal Gland Insufficiency by Tissue Engineering and Cell Therapy. Part 1: Regeneration of Lacrimal Gland Tissue: Can We Stimulate Lacrimal Gland Renewal In Vivo?, Curr Eye Res. 2016 Sep;41(9):1131-42. doi: 10.3109/02713683.2016.1148741. Epub 2016 Apr 26.


Spaniol K, Metzger M, Roth M, Greve B, Mertsch S, Geerling G, Schrader S. Engineering of a Secretory Active Three-Dimensional Lacrimal Gland Construct on the Basis of Decellularized Lacrimal Gland Tissue. Tissue Eng Part A. 2015 Oct;21(19-20):2605-17. doi: 10.1089/ten.TEA.2014.0694. Epub 2015 Sep 8. PubMed PMID: 26222647.

Massie I, Kureshi AK, Schrader S, Shortt AJ, Daniels JT. Optimization of optical and mechanical properties of real architecture for 3-dimensional tissue equivalents: Towards treatment of limbal epithelial stem cell deficiency. Acta Biomater. 2015 Sep 15;24:241-50. doi: 10.1016/j.actbio.2015.06.007. Epub 2015 Jun 17. PubMed PMID: 26092352; PubMed Central PMCID: PMC4550494.

Roth M, Spaniol K, Kordes C, Schwarz S, Mertsch S, Häussinger D, Rotter N, Geerling G, Schrader S. The Influence of Oxygen on the Proliferative Capacity and Differentiation Potential of Lacrimal Gland-Derived Mesenchymal Stem Cells. Invest Ophthalmol Vis Sci. 2015 Jul;56(8):4741-52. doi: 10.1167/iovs.14-15475. PubMed PMID: 26207311.

Roth M, Schrader S, Finis D, Spaniol K, MacKenzie C, Ackermann P, Geerling G. [Diagnostics of Infectious Corneal and Conjunctival Diseases]. Klin Monbl Augenheilkd. 2015 Jun;232(6):789-803; quiz 804-6. doi: 10.1055/s-0033-1358135. Epub 2015 May 27. German. PubMed PMID: 26018665.

Finis D, Ralla B, Karbe M, Borrelli M, Schrader S, Geerling G. Comparison of two different scheimpflug devices in the detection of keratoconus, regular astigmatism, and healthy corneas. J Ophthalmol. 2015;2015:315281. doi:10.1155/2015/315281. Epub 2015 Apr 14. PubMed PMID: 25954510; PubMed Central PMCID: PMC4411433.

Drechsler CC, Kunze A, Kureshi A, Grobe G, Reichl S, Geerling G, Daniels JT, Schrader S. Development of a conjunctival tissue substitute on the basis of plastic compressed collagen. J Tissue Eng Regen Med. 2015 Feb 10. doi: 10.1002/term.1991.PubMed PMID: 25676608

Borrelli M, Joepen N, Reichl S, Finis D, Schoppe M, Geerling G, Schrader S. Keratin films for ocular surface reconstruction: evaluation of biocompatibility in an in-vivo model. Biomaterials. 2015 Feb;42:112-20. doi: 10.1016/j.biomaterials.2014.11.038. Epub 2014 Dec 16. PubMed PMID: 25542799

Finis D, Schrader S, Geerling G. Therapieoptionen und Konzepte. Kapitel 7 des Buches Meibom-Drüsen-Dysfunktion – Aktuelle Diagnose und Therapieoptionen. Uni-Med Verlag 2015. ISBN 978-3-8374-1437-0.


Feng Y, Borrelli M, Reichl S, Schrader S, Geerling G. Review of alternative carrier materials for ocular surface reconstruction. Curr Eye Res. 2014 Jun;39(6):541-52. doi: 10.3109/02713683.2013.853803. Epub 2014 Jan 9. PubMed PMID: 24405104

Finis D, König C, Hayajneh J, Borrelli M, Schrader S*, Geerling G*. Six-Month Effects of a Thermodynamic Treatment for MGD and Implications of Meibomian Gland Atrophy. Cornea. 2014 Oct 15. [Epub ahead of print] PubMed PMID: 25321941. *shared senior authorship

Finis D, Ackermann P, Pischel N, König C, Hayajneh J, Borrelli M, Schrader S*, Geerling G*. Evaluation of Meibomian Gland Dysfunction and Local Distribution of Meibomian Gland Atrophy by Non-contact Infrared Meibography. Curr Eye Res. 2014 Oct 20:1-8. [Epub ahead of print] PubMed PMID: 25330304. *shared senior authorship

Schrader S, Finis D, Spaniol K, Roth M, Ackermann P, Geerling G. [Clinical Diagnostics for the Tear Film and the Ocular Surface.]. Klin Monbl Augenheilkd. 2014 Aug 12. [Epub ahead of print] German. PubMed PMID: 25116066.

Finis D, Pischel N, König C, Hayajneh J, Borrelli M, Schrader S*, Geerling G*. [Comparison of the OSDI and SPEED questionnaires for the evaluation of dry eye disease in clinical routine.]. Ophthalmologe. 2014 Jul 18. [Epub ahead of print] German. PubMed PMID: 25030896. *shared senior authorship

Finis D, Pischel N, Borrelli M, Schrader S*, Geerling G*. [Factors influencing the measurement of tear film lipid layer thickness with interferometry]. Klein Monbl Augenheilkd. 2014 Jun;231(6):603-10. doi: 10.1055/s-0034-1368536. Epub 2014 Jun 18. German. PubMed PMID: 24940758. *shared senior authorship


Finis D, Hayajneh J, König C, Borrelli M, Schrader S*, Geerling G*. Evaluation of an automated thermodynamic treatment (LipiFlow®) system for meibomian gland dysfunction: a prospective, randomized, observer-masked trial. Ocul Surf. 2014 Apr;12(2):146-54. doi: 10.1016/j.jtos.2013.12.001. Epub 2014 Jan 22. PubMed PMID: 24725326. *shared senior authorship

Feng Y, Borrelli M, Meyer-Ter-Vehn T, Reichl S, Schrader S*, Geerling G*. Epithelial wound healing on keratin film, amniotic membrane and polystyrene in vitro. Curr Eye Res. 2014 Jun;39(6):561-70. doi: 10.3109/02713683.2013.853804. Epub 2014 Jan 8. PubMed PMID: 24400943 *shared senior authorship

Finis D, Pischel N, Schrader S*, Geerling G*. Evaluation of Lipid Layer Thickness Measurement of the Tear Film as a Diagnostic Tool for Meibomian Gland Dysfunction. CORNEA-D-13-00336R2  *shared senior authorship

2012 and later

Borrelli M, Feng Y, Spaniol K, Geerling G, Schrader S.  New Developments in Matrices for Ocular Surface Reconstruction, Current Tissue Engineering, 2012

Borrelli M, Reichl S, Feng Y, Schargus M, Schrader S, Geerling G. In vitro characterization and ex vivo surgical evaluation of human hair keratin films in ocular surface reconstruction after sterilization processing. J Mater Sci Mater Med. 2012 Sep 27.

Schrader S, Tuft SJ, Beaconsfield M, Borrelli M, Geerling G, Daniels JT. Evaluation of Human MRC-5 Cells as a Feeder Layer in a Xenobiotic Free Culture System for Conjunctival Epithelial Progenitor Cells. Curr. Eye Res.

Schrader S, O'Callaghan AR, Tuft SJ, Beaconsfield M, Geerling G, Daniels JT. Wnt signalling in an in vitro niche model for conjunctival progenitor cells. Tissue Eng Regen Med. 2014 Dec;8(12):969-77. doi: 10.1002/term.1599. Epub 2012 Aug 30. PubMed PMID: 22933392.

Notara M, Schrader S, Daniels JT. The porcine limbal epithelial stem cell niche as a new model for the study of transplanted tissue-engineered human limbal epithelial cells. Tissue Eng Part A. 2011 Mar;17(5-6):741-50.

Schrader S, Notara M, Tuft SJ, Beaconsfield M, Geerling G, Daniels JT. Simulation of an in vitro niche environment that preserves conjunctival progenitor cells. Regen Med. 2010 Nov;5(6):877-89.

Schrader S, Notara M, Beaconsfield M, Tuft S, Geerling G, Daniels JT. Conjunctival epithelial cells maintain stem cell properties after long-term culture and cryopreservation. Regen Med. 2009 Sep;4(5):677-87

Schrader S, Kremling C, Klinger M, Laqua H, Geerling G. Cultivation of lacrimal gland acinar cells in a microgravity environment. Br J Ophthalmol. 2009 Aug;93(8):1121-5. Epub 2009 May 4

Schrader S, Wedel T, Kremling C Laqua H, Geerling G. Amniotic Membrane As A Carrier for Lacrimal Gland Acinar Cells. Graefes Arch Clin Exp Ophthalmol. 2007 Nov;245(11):1699-704. Epub 2007 Jun 12

Schrader S, Wedel T, Moll R, Geerling G. Combination of serum eye drops with hydrogel bandage contact lenses in the treatment of persistent epithelial defects. Graefes Arch Clin Exp Ophthalmol. 2006 Oct;244(10):1345-9. Epub 2006 Mar 17

Schrader S, Liu L, Kasper K, Geerling G. Generation of two- and three-dimensional lacrimal gland constructs. Dev Ophthalmol. 2010;45:49-56. Epub 2010 May 18 (Buchbeitrag)

Schrader S, Notara M, Beaconsfield M, Tuft SJ, Daniels JT, Geerling G. Tissue engineering for conjunctival reconstruction: established methods and future outlooks. Curr Eye Res. 2009 Nov;34(11):913-24.

Notara M, Alatza A, Gilfillan J, Harris AR, Levis HJ, Schrader S, Vernon A, Daniels JT. In sickness and in health: Corneal epithelial stem cell biology, pathology and therapy. Exp Eye Res. 2010 Feb;90(2):188-95. Epub 2009 Oct 17.

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