Publikationen

Tometten I, Landmann S, Kantauskaite M, Lamberti J, Hillebrandt J, Müller L, Kittel M, Kolb T, Ivens K, Schmitz M, Voges A, Adams O, Andrée M, Schaal H, Lübke N, Königshausen E, Rump LC, Stegbauer J, Timm J. Factors associated with vaccine-induced T cell immune responses against SARS-CoV-2 in kidney transplant recipients. J Infect Dis. 2022 Nov 21:jiac449. 

Walker A, Schwarz T, Brinkmann-Paulukat J, Wisskirchen K, Menne C, Alizei ES, Kefalakes H, Theissen M, Hoffmann D, Schulze Zur Wiesch J, Maini MK, Cornberg M, Kraft AR, Keitel V, Bock HH, Horn PA, Thimme R, Wedemeyer H, Heinemann FM, Luedde T, Neumann-Haefelin C, Protzer U, Timm J. Immune escape pathways from the HBV core18-27 CD8 T cell response are driven by individual HLA class I alleles. Front Immunol. 2022 Nov 10;13:1045498.

Fischer JC, Balz V, Jazmati D, Bölke E, Freise NF, Keitel V, Feldt T, Jensen BO, Bode J, Lüdde T, Häussinger D, Adams O, Schneider EM, Enczmann J, Rox JM, Hermsen D, Schulze-Bosse K, Kindgen-Milles D, Knoefel WT, van Griensven M, Haussmann J, Tamaskovics B, Plettenberg C, Scheckenbach K, Corradini S, Pedoto A, Maas K, Schmidt L, Grebe O, Esposito I, Ehrhardt A, Peiper M, Buhren BA, Calles C, Stöhr A, Gerber PA, Lichtenberg A, Schelzig H, Flaig Y, Rezazadeh A, Budach W, Matuschek C.  Prognostic markers for the clinical course in the blood of patients with SARS-CoV-2 infection. Eur J Med Res. 2022 Nov 21;27(1):255.

Meister TL, Tao R, Brüggemann Y, Todt D, Steinmann J, Timm J, Drexler I, Steinmann E. Efficient Inactivation of Monkeypox Virus by World Health Organization‒Recommended Hand Rub Formulations and Alcohols. Emerg Infect Dis. 2022 Nov 17;29(1). doi: 10.3201/eid2901.221429.

Freise NF, Gliga S, Fischer J, Lübke N, Lutterbeck M, Schöler M, Bölke E, Orth HM, Feldt T, Roemmele C, Wilke D, Schneider J, Wille K, Hohmann C, Strauss R, Hower M, Ruf A, Schubert J, Isberner N, Stecher M, Pilgram L, Vehreschild JJ; LEOSS Study Group, Hanses F, Luedde T, Jensen B. Convalescent plasma treatment for SARS-CoV-2 infected high-risk patients: a matched pair analysis to the LEOSS cohort. Sci Rep. 2022 Nov 9;12(1):19035. 

Müller L, Andrée M, Moskorz W, Drexler I, Hauka S, Ptok J, Walotka L, Grothmann R, Hillebrandt J, Ritchie A, Peter L, Walker A, Timm J, Adams O, Schaal H.  Adjusted COVID-19 booster schedules balance age-dependent differences in antibody titers benefitting risk populations. Front Aging. 2022 Oct 12;3:1027885.

Houwaart T, Belhaj S, Tawalbeh E, Nagels D, Fröhlich Y, Finzer P, Ciruela P, Sabrià A, Herrero M, Andrés C, Antón A, Benmoumene A, Asskali D, Haidar H, von Dahlen J, Nicolai J, Stiller M, Blum J, Lange C, Adelmann C, Schroer B, Osmers U, Grice C, Kirfel PP, Jomaa H, Strelow D, Hülse L, Pigulla M, Kreuzer P, Tyshaieva A, Weber J, Wienemann T, Kohns Vasconcelos M, Hoffmann K, Lübke N, Hauka S, Andree M, Scholz CJ, Jazmati N, Göbels K, Zotz R, Pfeffer K, Timm J, Ehlkes L, Walker A, Dilthey AT; German COVID-19 OMICS Initiative (DeCOI); German COVID-19 OMICs Initiative (DeCOI). Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021. Euro Surveill. 2022 Oct;27(43). doi: 10.2807/1560-7917.ES.2022.27.43.2101089.

Brinks R, Küchenhoff H, Timm J, Kurth T, Hoyer A. Epidemiological measures for assessing the dynamics of the SARS-CoV-2-outbreak: Simulation study about bias by incomplete case-detection. PLoS One. 2022 Oct 26;17(10):e0276311.

Gliga S, Luebke N, Killer A, Gruell H, Walker A, Dilthey AT, Lohr C, Flaßhove C, Orth HM, Feldt T, Bode JG, Klein F, Timm J, Luedde T, Jensen BO. Rapid selection of sotrovimab escape variants in SARS-CoV-2 Omicron infected immunocompromised patients. Clin Infect Dis. 2022 Oct 3:ciac802.

Lübke N, Repges K, Menne C, Walker A, Jensen BO, Freise NF, Gliga S, Eickhoff SB, Bosse HM, Adams O, Timm J. Quantitative analysis of different respiratory specimens on two automated test systems for detection of SARS-CoV-2 RNA. Diagn Microbiol Infect Dis. 2022 Aug 26;105(1):115800. 

Papan C, Argentiero A, Adams O, Porwoll M, Hakim U, Farinelli E, Testa I, Pasticci MB, Mezzetti D, Perruccio K, Simon A, Liese JG, Knuf M, Stein M, Yacobov R, Bamberger E, Schneider S, Esposito S, Tenenbaum T. Association of viral load with TRAIL, IP-10, CRP biomarker signature and disease severity in children with respiratory tract infection or fever without source: A prospective, multicentre cohort study. J Med Virol. 2022 Aug 31. doi: 10.1002/jmv.28113.

Dragano N, Dortmann O, Timm J, Mohrmann M, Wehner R, Rupprecht CJ, Scheider M, Mayatepek E, Wahrendorf M. Association of Household Deprivation, Comorbidities, and COVID-19 Hospitalization in Children in Germany, January 2020 to July 2021. JAMA Netw Open. 2022 Oct 3;5(10):e2234319. 


Kantauskaite M, Müller L, Hillebrandt J, Lamberti J, Fischer S, Kolb T, Ivens K, Koch M, Andree M, Lübke N, Schmitz M, Luedde T, Orth HM, Feldt T, Schaal H, Adams O, Schmidt C, Kittel M, Königshausen E, Rump LC, Timm J, Stegbauer J. Immune response to third SARS-CoV-2 vaccination in seronegative kidney transplant recipients: Possible improvement by mycophenolate mofetil reduction. Clin Transplant. 2022 Aug 23:e14790.

Müller L, Ptok J, Nisar A, Antemann J, Grothmann R, Hillebrand F, Brillen AL, Ritchie A, Theiss S, Schaal H  Modeling splicing outcome by combining 5'ss strength and splicing regulatory elements. Nucleic Acids Res. 2022 Aug 10:gkac663. doi: 10.1093/nar/gkac663.

Adams O, Andrée M, Hermsen D, Lübke N, Timm J, Schaal H, Müller L. Comparison of commercial SARS-CoV-2 surrogate neutralization assays with a full virus endpoint dilution neutralization test in two different cohorts. J Virol Methods. 2022;307:114569. 

Müller-Schiffmann A, Michon M, Lingappa AF, Yu SF, Du L, Deiter F, Broce S, Mallesh S, Crabtree J, Lingappa UF, Macieik A, Müller L, Ostermann PN, Andrée M, Adams O, Schaal H, Hogan RJ, Tripp RA, Appaiah U, Anand SK, Campi TW, Ford MJ, Reed JC, Lin J, Akintunde O, Copeland K, Nichols C, Petrouski E, Moreira AR, Jiang IT, DeYarman N, Brown I, Lau S, Segal I, Goldsmith D, Hong S, Asundi V, Briggs EM, Phyo NS, Froehlich M, Onisko B, Matlack K, Dey D, Lingappa JR, Prasad MD, Kitaygorodskyy A, Solas D, Boushey H, Greenland J, Pillai S, Lo MK, Montgomery JM, Spiropoulou CF, Korth C, Selvarajah S, Paulvannan K, Lingappa VR. A Pan-respiratory Antiviral Chemotype Targeting a Transient Host Multiprotein Complex. bioRxiv. 2022 Jul 19:2021.01.17.426875.

Kuechler AS, Weinhold S, Boege F, Adams O, Müller L, Babor F, Bennstein SB, Pham TU, Hejazi M, Reusing SB, Hermsen D, Uhrberg M, Schulze-Bosse K. A Diagnostic Strategy for Gauging Individual Humoral Ex Vivo Immune Responsiveness Following COVID-19 Vaccination. Vaccines (Basel). 2022 Jun 29;10(7):1044.

Orth HM, Fuchs A, Lübke N, Jensen BO, Luedde T. Recurrent parvovirus B19 viremia resulting in two episodes of hemophagocytic lymphohistiocytosis. Virol J. 2022 Jun 25;19(1):107. 

Hoogeveen RC, Dijkstra S, Bartsch LM, Drescher H, Aneja J, Robidoux MP, Cheney JA, Timm J, Gehring A, Fonseca de Sousa PS, Ximenez L, Peliganga LB, Pitts A, Blackburn FE, Boonstra A, Kim AY, Lewis-Ximenez LL, Lauer GM. Hepatitis B virus-specific CD4 T-cell responses differentiate functional cure from chronic surface antigen+ infection. J Hepatol. 2022 Jun 15:S0168-8278(22)00366-X. 

Wildner NH, Walker A, Brauneck F, Ditt V, Peine S, Huber S, Haag F, Beisel C, Timm J, Schulze Zur Wiesch J. Transcriptional Pattern Analysis of Virus-Specific CD8+ T Cells in Hepatitis C Infection: Increased Expression of TOX and Eomesodermin During and After Persistent Antigen Recognition. Front Immunol. 2022 Jun 6;13:886646.

Eberle RJ, Gering I, Tusche M, Ostermann PN, Müller L, Adams O, Schaal H, Olivier DS, Amaral MS, Arni RK, Willbold D, Coronado MA. Design of D-Amino Acids SARS-CoV-2 Main Protease Inhibitors Using the Cationic Peptide from Rattlesnake Venom as a Scaffold. Pharmaceuticals (Basel). 2022 Apr 27;15(5):540.

Horemheb-Rubio G, Eggeling R, Schmeiβer N, Pfeifer N, Lengauer T, Gärtner BC, Prifert C, Kochanek M, Scheid C, Adams O, Kaiser R; Respiratory Virus Network. Respiratory viruses dynamics and interactions: ten years of surveillance in central Europe. BMC Public Health. 2022 Jun 11;22(1):1167.

Backhaus I, Hermsen D, Timm J, Boege F, Lübke N, Göbels K, von der Lieth D, Dragano N. Underascertainment of COVID-19 cases among first responders: a seroepidemiological study. Occup Med (Lond). 2022 Apr 19;72(3):225-228.

Liu Z, Kilic G, Li W, Bulut O, Gupta MK, Zhang B, Qi C, Peng H, Tsay HC, Soon CF, Mekonnen YA, Ferreira AV, van der Made CI, van Cranenbroek B, Koenen HJPM, Simonetti E, Diavatopoulos D, de Jonge MI, Müller L, Schaal H, Ostermann PN, Cornberg M, Eiz-Vesper B, van de Veerdonk F, van Crevel R, Joosten LAB, Domínguez-Andrés J, Xu CJ, Netea MG, Li Y. Multi-Omics Integration Reveals Only Minor Long-Term Molecular and Functional Sequelae in Immune Cells of Individuals Recovered From COVID-19. Front Immunol. 2022 Apr 6;13:838132. 

Adams O, Andrée M, Rabl D, Ostermann PN, Schaal H, Lehnert E, Ackerstaff S, Müller L, Fischer JC. Humoral response to SARS-CoV-2 and seasonal coronaviruses in COVID-19 patients. J Med Virol. 2022 Mar;94(3):1096-1103. 

Backhaus I, Hermsen D, Timm J, Boege F, Lübke N, Degode T, Göbels K, Dragano N. SARS-CoV-2 seroprevalence and determinants of infection in young adults: a population-based seroepidemiological study. Public Health. 2022 Mar 23;207:54-61.

Walker A, Houwaart T, Finzer P, Ehlkes L, Tyshaieva A, Damagnez M, Strelow D, Duplessis A, Nicolai J, Wienemann T, Tamayo T, Kohns Vasconcelos M, Hülse L, Hoffmann K, Lübke N, Hauka S, Andree M, Däumer MP, Thielen A, Kolbe-Busch S, Göbels K, Zotz R, Pfeffer K, Timm J, Dilthey AT; German COVID-19 OMICS Initiative (DeCOI). Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Clusters Based on Integrated Genomic Surveillance, Outbreak Analysis and Contact Tracing in an Urban Setting. Clin Infect Dis. 2022 Mar 23;74(6):1039-1046. 

Kamin W, Adams O, Kardos P, Matthys H, Meister N, Strassburg CP. Liver Involvement in Acute Respiratory Infections in Children and Adolescents - Results of a Non-interventional Study. Front Pediatr. 2022 Mar 29;10:840008. 

Habermann D, Kharimzadeh H, Walker A, Li Y, Yang R, Kaiser R, Brumme ZL, Timm J, Roggendorf M, Hoffmann D. HAMdetector: A Bayesian regression model that integrates information to detect HLA-associated mutations. Bioinformatics. 2022 Mar 3:btac134. 

Müller L, Ostermann PN, Schaal H, Salla S, Timm J, Geerling G, Menzel-Severing J. RT-PCR Testing of Organ Culture Medium for Corneal Storage Fails to Detect SARS-CoV-2 Infection Due to Lack of Viral Replication. Pathogens. 2022 Jan 22;11(2):133.

Moorlag SJCFM, Taks E, Ten Doesschate T, van der Vaart TW, Janssen AB, Müller L, Ostermann P, Dijkstra H, Lemmers H, Simonetti E, Mazur M, Schaal H, Ter Heine R, van de Veerdonk FL, Bleeker-Rovers CP, van Crevel R, Ten Oever J, de Jonge MI, Bonten MJ, van Werkhoven CH, Netea MG. Efficacy of Bacillus Calmette-Guérin vaccination against respiratory tract infections in the elderly during the Covid-19 pandemic. Clin Infect Dis. 2022 Mar 5:ciac182.

Tufa TB, Fuchs A, Orth HM, Lübke N, Knops E, Heger E, Jarso G, Hurissa Z, Eggers Y, Häussinger D, Luedde T, Jensen BO, Kaiser R, Feldt T. Characterization of HIV-1 drug resistance among patients with failure of second-line combined antiretroviral therapy in central Ethiopia. HIV Med. 2022 Feb;23(2):159-168. 

Kantauskaite M, Müller L, Kolb T, Fischer S, Hillebrandt J, Ivens K, Andree M, Luedde T, Orth HM, Adams O, Schaal H, Schmidt C, Königshausen E, Rump LC, Timm J, Stegbauer J. Intensity of mycophenolate mofetil treatment is associated with an impaired immune response to SARS-CoV-2 vaccination in kidney transplant recipients. Am J Transplant. 2022 Feb;22(2):634-639. 

Bötticher B, Dinkelbach L, Hillebrecht M, Adams O, Dechert O, Trocan L, Neubert J, Borkhardt A, Janßen G. High rate of clinically unrecognized SARS-CoV-2 infections in pediatric palliative care patients. Eur J Pediatr. 2022 Feb;181(2):847-851. 

Senff T, Menne C, Cosmovici C, Lewis-Ximenez LL, Aneja J, Broering R, Kim AY, Westendorf AM, Dittmer U, Scherbaum N, Lauer GM, Timm J. Peripheral blood iNKT cell activation correlates with liver damage during acute hepatitis C. JCI Insight. 2022 Jan 25;7(2):e155432.

Rothenburg J, Rink-Baron S, Mueller L, Ostermann PN, Fischer J, Stegbauer J, Moldenhauer A. COVID-19 antibody donation using immunoadsorption: Report of two cases. Transfus Apher Sci. 2021 Oct;60(5):103193.

Müller L, Andrée M, Moskorz W, Drexler I, Walotka L, Grothmann R, Ptok J, Hillebrandt J, Ritchie A, Rabl D, Ostermann PN, Robitzsch R, Hauka S, Walker A, Menne C, Grutza R, Timm J, Adams O, Schaal H.
 Age-dependent Immune Response to the Biontech/Pfizer BNT162b2 Coronavirus Disease 2019 Vaccination. Clin Infect Dis. 2021 Dec 6;73(11):2065-2072. 

 

 zuletzt aktualisiert am 30.11.2022


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