Publikationen

Lübke N, Jensen B, Hüttig F, Feldt T, Walker A, Thielen A, Däumer M, Obermeier M, Kaiser R, Knops E, Heger E, Sierra S, Oette M, Lengauer T, Timm J, Häussinger D. Failure of Dolutegravir First-Line ART with Selection of Virus Carrying R263K and G118R. N Engl J Med. 2019 Aug 29;381(9):887-889.

Manser AR, Scherenschlich N, Thöns C, Hengel H, Timm J, Uhrberg M. KIR Polymorphism Modulates the Size of the Adaptive NK Cell Pool in Human Cytomegalovirus-Infected Individuals. J Immunol. 2019 Sep 13. pii: ji1900423. doi: 10.4049/jimmunol.1900423.

Huang A, Shinde PV, Huang J, Senff T, Xu HC, Margotta C, Häussinger D, Willnow TE, Zhang J, Pandyra AA, Timm J, Weggen S, Lang KS, Lang PA. Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells. JCI Insight. 2019 Sep 5;4(17). 

Lundtoft C, Awuah AA, Güler A, Harling K, Schaal H, Mayatepek E, Phillips RO, Nausch N, Owusu-Dabo E, Jacobsen M. An IL7RA exon 5 polymorphism is associated with impaired IL-7Rα splicing and protection against tuberculosis in Ghana. Genes Immun. 2019 Jul;20(6):514-519.

Parczewski M, Kordek J, Janczewska E, Pisula A, Łojewski W, Socha Ł, Wawrzynowicz-Syczewska M, Bociąga-Jasik M, Szymczak A, Cielniak I, Siwak E, Mularska E, Aksak-Wąs B, Urbańska A, Lübke N. Hepatitis C virus (HCV) genotype 1 NS5A resistance-associated variants are associated with advanced liver fibrosis independently of HCV-transmission clusters. Clin Microbiol Infect. 2019 Apr;25(4):513.e1-513.e6.

Sinnecker T, Hadisurya J, Schneider-Hohendorf T, Schwab N, Wrede K, Gembruch O, Gold R, Hellwig K, Pilgram-Pastor S, Adams O, Albrecht P, Hartung HP, Aktas O, Kraemer M. Extensive immune reconstitution inflammatory syndrome in Fingolimod-associated PML: a case report with 7 Tesla MRI data. BMC Neurol. 2019 Aug 9;19(1):190. doi: 10.1186/s12883-019-1407-2.

Gonnissen S, Ptok J, Goy C, Jander K, Jakobs P, Eckermann O, Kaisers W, von Ameln F, Timm J, Ale-Agha N, Haendeler J, Schaal H, Altschmied J. High Concentration of Low-Density Lipoprotein Results in Disturbances in Mitochondrial Transcription and Functionality in Endothelial Cells. Oxid Med Cell Longev. 2019 Jun 10;2019:7976382. doi: 10.1155/2019/7976382. eCollection 2019.

Wong YC, Croft S, Smith SA, Lin LCW, Cukalac T, La Gruta NL, Drexler I, Tscharke DC. Vaccinia Virus Strain MVA can Induce Optimal CD8+ T cell responses to Directly Primed Antigens Depending on Vaccine Design. J Virol. 2019 Aug 2. pii: JVI.01154-19. doi: 10.1128/JVI.01154-19.

Kugler F, Drexler I, Protzer U, Hoffmann D, Moeini H. Generation of recombinant MVA-norovirus: a comparison study of bacterial artificial chromosome- and marker-based systems. Virol J. 2019 Aug 9;16(1):100. doi: 10.1186/s12985-019-1212-y.

Ptok J, Müller L, Theiss S, Schaal H. Context matters: Regulation of splice donor usage.Biochim Biophys Acta Gene Regul Mech. 2019 Jun 13. pii: S1874-9399(18)30502-9. doi: 10.1016

Yang S, Wang L, Pan W, Bayer W, Thoens C, Heim K, Dittmer U, Timm J, Wang Q, Yu Q, Luo J, Liu Y, Hofmann M, Thimme R, Zhang X, Chen H, Wang H, Feng X, Yang X, Lu Y, Lu M, Yang D, Liu J. MMP2/MMP9-mediated CD100 shedding is crucial for inducing intrahepatic anti-HBV CD8 T cell responses and HBV clearance. J Hepatol. 2019 Jun 4. pii: S0168-8278(19)30299-5. doi: 10.1016/j.jhep.2019.05.013.

Hillebrand F, Ostermann PN, Müller L, Degrandi D, Erkelenz S, Widera M, Pfeffer K, Schaal H. Gymnotic Delivery of LNA Mixmers Targeting Viral SREs Induces HIV-1 mRNA Degradation. Int J Mol Sci. 2019 Mar 3;20(5). pii: E1088. doi: 10.3390/ijms20051088

Luteijn RD, van Diemen F, Blomen VA, Boer IGJ, Manikam Sadasivam S, van Kuppevelt TH, Drexler I, Brummelkamp TR, Lebbink RJ, Wiertz EJ. A genome-wide haploid genetic screen identifies heparan sulfate-associated genes and the macropinocytosis modulator TMED10 as factors supporting vaccinia virus infection. J Virol. 2019 Apr 17. pii: JVI.02160-18. doi: 10.1128

Blankenbach K, Schwab N, Hofner B, Adams O, Keller-Stanislawski B, Warnke C. Natalizumab-associated progressive multifocal leukoencephalopathy in Germany. Neurology. 2019 May 7;92(19):e2232-e2239. 

Spekker-Bosker K, Ufermann CM, Maywald M, Zimmermann A, Domröse A, Woite C, Däubener W, Eller SK. hCMV-Mediated Immune Escape Mechanisms Favor Pathogen Growth and Disturb the Immune Privilege of the Eye. Int J Mol Sci. 2019 Feb 16;20(4). pii: E858. doi: 10.3390/ijms20040858.

Walker A, Ennker KS, Kaiser R, Lübke N, Timm J. A pan-genotypic Hepatitis C Virus NS5A amplification method for reliable genotyping and resistance testing. J Clin Virol. 2019 Jan 30;113:8-13.  

Kemming J, Reeves E, Nitschke K, Widmeier V, Emmerich F, Hermle T, Gostick E, Walker A, Timm J, Price DA, Hofmann M, Thimme R, James E, Neumann-Haefelin C. ERAP1 allotypes impact the epitope repertoire of virus-specific CD8+ T cell responses in acute hepatitis C virus infection. J Hepatol. 2019 Feb 12. pii: S0168-8278(19)30111-4. doi: 10.1016/j.jhep.2019.01.034.

Karimzadeh H, Kiraithe MM, Oberhardt V, Alizei ES, Bockmann J, Zur Wiesch JS, Budeus B, Hoffmann D, Wedemeyer H, Cornberg M, Krawczyk A, Rashidi-Alavijeh J, Rodríguez-Frías F, Casillas R, Buti M, Smedile A, Alavian SM, Heinold A, Emmerich F, Panning M, Gostick E, Price DA, Timm J, Hofmann M, Raziorrouh B, Thimme R, Protzer U, Roggendorf M, Neumann-Haefelin C. Mutations in Hepatitis D Virus Allow it to Escape Detection by CD8+ T Cells and Evolve at the Population Level. Gastroenterology. 2019 Feb 12. pii: S0016-5085(19)30366-X. doi: 10.1053/j.gastro.2019.02.003

Verheyen J, Thielen A, Lübke N, Dirks M, Widera M, Dittmer U, Kordales L, Däumer M, Jong TCM, Wensing AMJ, Kaiser R, Nijhuis M, Esser S. Rapid rebound of a preexisting CXCR4-tropic HIV variant after allogeneic transplantation with CCR5 delta32 homozygous stem cells. Clin Infect Dis. 2019 Feb 1;68(4):684-687.

Xia Y, Pan W, Ke X, Skibbe K, Walker A, Hoffmann D, Lu Y, Yang X, Feng X, Tong Q, Timm J, Yang D. Differential escape of HCV from CD8+ T cell selection pressure between China and Germany depends on the presenting HLA class I molecule. J Viral Hepat. 2019 Jan;26(1):73-82.

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