Heterogeneity in clinically diagnosed type 1 diabetes: characterising a unique cohort with maintained C-peptide secretion in Ghana.
Aniagyei W, Sarfo-Kantanka O, Mohayideen S, Vivekanandan MM, Adankwah E, Asibey SO, Boateng AO, Owusu E, Arthur JF, Yeboah A, Ahor HS, Owusu DO, Huttasch M, Karusheva Y, Burkart V, Wagner R, Roden M, Balz V, Enczmann J, Sterzenbach M, Kummer S, Meissner T, Herebian D, Mayatepek E, Jacobsen M, Phillips RO, Seyfarth J.
Diabetologia. 2025 Nov 1. Pubmed.

• Monocyte transcriptome signatures of inflammation and enhanced neutrophil recruitment characterize immunopathology in the blood of tuberculosis patients.
  Ahor HS, Vivekanandan MM, Adankwah E, Minadzi D, Acheampong I, Aniagyei W, Yeboah A, Arthur JF, Lamptey M, Abass MK, Kumbel F, Osei-Yeboah F, Gawusu A, Petzsch P, Köhrer K, Debrah LB, Owusu DO, Debrah A, Mayatepek E, Seyfarth J, Phillips RO, Jacobsen M.
  J Infect. 2024 Dec;89(6):106359. Pubmed.
• Concomitant parasite infections influence tuberculosis immunopathology and favor rapid sputum conversion of pulmonary tuberculosis patients.
  Yeboah A, Vivekanandan M, Adankwah E, Owusu DO, Aniagyei W, Minadzi D, Acheampong I, Arthur JF, Lamptey M, Abass MK, Kumbel F, Osei-Yeboah F, Gawusu A, Debrah LB, Debrah A, Mayatepek E, Seyfarth J, Phillips RO, Jacobsen M.
  Ann Clin Microbiol Antimicrob. 2024 Nov 7;23(1):97. Pubmed.
• BCG Vaccination-Associated Lower HbA1c and Increased CD25 Expression on CD8^+^ T Cells in Patients with Type 1 Diabetes in Ghana.
  Aniagyei W, Mohayideen S, Sarfo-Kantanka O, Bittner S, Vivekanandan MM, Arthur JF, Boateng AO, Yeboah A, Ahor HS, Asibey SO, Owusu E, Herebian D, Huttasch M, Burkart V, Wagner R, Roden M, Adankwah E, Owusu DO, Mayatepek E, Jacobsen M, Phillips RO, Seyfarth J.
  Vaccines (Basel). 2024 Apr 24;12(5):452. Pubmed.
• High common-γ cytokine receptor levels promote expression of Interleukin-2/Interleukin-7 receptor α-chains with implications on T-cell differentiation and function.
  Kim JY, Mayatepek E, Seyfarth J, Jacobsen M.
  Immunology. 2024 Sep;173(1):93-105. Pubmed.
• Immunopathology in human pulmonary tuberculosis: Inflammatory changes in the plasma milieu and impaired host immune cell functions.
  Ahor HS, Vivekanandan M, Harelimana JD, Owusu DO, Adankwah E, Seyfarth J, Phillips R, Jacobsen M.
  Immunology. 2024 Jun;172(2):198-209. Pubmed.
• Differences in PPD- and mitogen-induced T-cell activation marker expression characterize immunopathology in acute tuberculosis patients.
  Acheampong I, Minadzi D, Laing EF, Frimpong M, Vivekanandan MM, Yeboah A, Adankwah E, Aniagyei W, Arthur JF, Lamptey M, Abass MK, Kumbel F, Osei-Yeboah F, Gawusu A, Debrah LB, Owusu DO, Debrah A, Mayatepek E, Seyfarth J, Phillips RO, Jacobsen M.
  Eur J Clin Microbiol Infect Dis. 2024 Mar;43(3):611-616. Pubmed.

• Diminished Interleukin-7 receptor expression on T-cell subsets in tuberculosis patients. Acheampong I, Minadzi D, Adankwah E, Aniagyei W, Vivekanandan MM, Yeboah A, Arthur JF, Lamptey M, Abass MK, Kumbel F, Osei-Yeboah F, Gawusu A, Laing EF, Batsa Debrah L, Owusu DO, Debrah A, Mayatepek E, Seyfarth J, Phillips RO, Jacobsen M. Human Immunology. Pubmed.

• Monocyte pathology in human tuberculosis is due to plasma milieu changes and aberrant STAT signalling. Ahor HS, Schulte R, Adankwah E, Harelimana JD, Minadzi D, Acheampong I, Vivekanandan MM, Aniagyei W, Yeboah A, Arthur JF, Lamptey M, Abass MK, Kumbel F, Osei-Yeboah F, Gawusu A, Debrah LB, Owusu DO, Debrah A, Mayatepek E, Seyfarth J, Phillips RO, Jacobsen M.  Immunology. Pubmed.

• Memory B-cells are enriched in the blood of patients with acute Buruli ulcer disease: a prospective observational study. Adjei JK, Aniagyei W, Adankwah E, Seyfarth J, Mayatepek E, Berko DA, Ackam N, Annani-Akollor ME, Sakyi SA, Amoako YA, Owusu D, Jacobsen M, Phillips RO. BMC Infectious Diseases. Pubmed.

• BCG-Vaccinated Children with Contact to Tuberculosis Patients Show Delayed Conversion of Mycobacterium tuberculosis-Specific IFN-γ Release. Owusu DO, Adankwah E, Aniagyei W, Acheampong I, Minadzi D, Yeboah A, Arthur JF, Lamptey M, Vivekanandan MM, Abass MK, Kumbel F, Osei-Yeboah F, Gawusu A, Batsa Debrah L, Debrah A, Mayatepek E, Seyfarth J, Phillips RO, Jacobsen M. Vaccines (Basel). Pubmed.

• Impaired T-cell response to phytohemagglutinin (PHA) in tuberculosis patients is associated with high IL-6 plasma levels and normalizes early during anti-mycobacterial treatment. Vivekanandan MM, Adankwah E, Aniagyei W, Acheampong I, Minadzi D, Yeboah A, Arthur JF, Lamptey M, Abass MK, Kumbel F, Osei-Yeboah F, Gawusu A, Debrah LB, Owusu DO, Debrah A, Mayatepek E, Seyfarth J, Phillips RO, Jacobsen M. Infection. Pubmed.

• Plasma cytokine levels characterize disease pathogenesis and treatment response in tuberculosis patients. Vivekanandan MM, Adankwah E, Aniagyei W, Acheampong I, Yeboah A, Arthur JF, Lamptey MNK, Abass MK, Gawusu A, Kumbel F, Osei-Yeboah F, Debrah LB, Owusu DO, Debrah A, Mayatepek E, Seyfarth J, Phillips RO, Jacobsen M. INFECTION. Pubmed
• Doxycycline treatment of Mansonella perstans infected individuals affects immune cell activation and causes long-term T-cell polarization.Aniagyei W, Adjei JK, Adankwah E, Seyfarth J, Mayatepek E, Berko DA, Sakyi SA, Debrah LB, Debrah AY, Hoerauf A, Owusu DO, Phillips RO, Jacobsen M. Doxycycline treatment of Mansonella perstans infected individuals affects immune cell activation and causes long-term T-cell polarization. CLINICAL INFECTIOUS DISEASES. Pubmed
• Cytokine-induced transient monocyte IL-7Ra expression and the serum milieu in tuberculosis. Harelimana JD, Ahor HS, Benner B, Hellmuth S, Adankwah E, Minadzi D, Aniagyei W, Lamptey MNK, Arthur J, Yeboah A, Abass MK, Debrah LB, Owusu DO, Mayatepek E, Seyfarth J, Phillips RO, Jacobsen M.  EUROPEAN JOURNAL OF IMMUNOLOGY. Pubmed
• PPE51 mediates uptake of trehalose across the mycomembrane of Mycobacterium tuberculosis. Babu Sait MR, Koliwer-Brandl H, Stewart JA, Swarts BM, Jacobsen M, Ioerger TR, Kalscheuer R. SCIENTIFIC REPORTS. Pubmed
• Interleukin-7 and soluble Interleukin-7 receptor levels in type 1 diabetes - Impact of IL7RA polymorphisms, HLA risk genotypes and clinical features. Hoffmann M, Enczmann J, Balz V, Kummer S, Reinauer C, Döing C, Förtsch K, Welters A, Kohns Vasconcelos M, Mayatepek E, Meissner T, Jacobsen M, Seyfarth J. CLINICAL IMMUNOLOGY. Pubmed

• Aberrant plasma IL-7 and soluble IL-7 receptor levels indicate impaired T-cell response to IL-7 in human tuberculosis. Lundtoft C, Afum-Adjei Awuah A, Rimpler J, Harling K, Nausch N, Kohns M, Adankwah E, Lang F, Olbrich L, Mayatepek E, Owusu-Dabo E, Jacobsen M. PLOS PATHOGENS. PubMed
• Dominant TNFa and impaired IL-2 cytokine profiles of CD4+ T cells from Children with type-1-diabetes. Seyfarth J, Foertsch K, Ahlert H, Laws H-J, Karges B, Deenen R, Koehrer K, Mayatepek E, Meissner T, Jacobsen M. IMMUNOLOGY AND CELL BIOLOGY. PubMed
• Alternative Quantiferon cytokines for diagnosis of children with active tuberculosis and HIV co-infection in Ghana. LundtoftC, Awuah AA, Nausch N, Enimil A, Mayatepek E, Owusu-Dabo E, JacobsenM. MEDICAL MICROBIOLOGY AND IMMUNOLOGY. PubMed
• A novel mycobacterial in vitro infection assay identifies differences of induced macrophage apoptosis between CD4+ and CD8+ T cells. Nkwouano V, Witkowski S, Rehberg N, Kalscheuer R, NauschN, Mayatepek E, JacobsenM. PLOS ONE. PubMed
• Multiple cytokines for detection of Mycobacterium tuberculosis infection in children with tuberculosis. Nausch N, Lundtoft C, Schulz G, Henckel H, Mayatepek E, Fleischer B, Marx FM, Jacobsen M. THE INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE. PubMed
• Analysis of Mycobacterium ulcerans-specific T-cell cytokines for diagnosis of Buruli ulcer disease and as potential indicator for disease progression. Nausch N, Antwi-Berko D, Mubarik Y, Abass KM, Owusu W, Owusu-Dabo E, Debrah LB, Debrah AY, JacobsenM, Phillips RO. PLoS NEGLECTED TROPICAL DISEASES. PubMed
• Re: "It May Be Too Early to Try to Prove the Effect of Deworming on Tuberculin Reactivity". Van der Zalm MM, van Soelen N, Mandalakas AM, JacobsenM, Detjen AK, Marx FM, Grewal HM, Cotton MF, Walzl G, HesselingAC. PEDIATRIC INFECTIOUS DISEASES JOURNAL. PubMed
• Epidemiology of Mansonella perstans in the middle belt of Ghana. Debrah LB, Nausch N, Opoku VS, Owusu W, Mubarik Y, Berko DA, Wanji S, Layland LE, Hoerauf A, Jacobsen M, Debrah AY, Phillips RO. PARASITES & VECTORS. PubMed

• The Effect of Deworming on Tests of Tuberculosis Infection in Children with Recent Tuberculosis Exposure: A Randomized Controlled Trial. Van der Zalm MM, van Soelen N, Mandalakas A M, Jacobsen M, Detjen AK, Marx FM, Grewal, HM, Cotton MF, Walzl G, Hesseling, AC. PEDIATRIC INFECTIOUS DISEASES JOURNAL. PubMed

• Rapid detection and immune characterization of Mycobacterium abscessus infection in cystic fibrosis patients. Steindor M, Nkwouano V, Mayatepek E, Mackenzie CR, Schramm D, Jacobsen M. PLOS ONE. PubMed

• Dynamics of T-cell IFN-γ and miR-29a expression during active pulmonary tuberculosis. Afum-Adjei Awuah A, Ueberberg B, Owusu-Dabo E, Frempong M, Jacobsen M. INTERNATIONAL IMMUNOLOGY. PubMed

• Co-infection with Mycobacterium ulcerans and Mansonella perstans among Buruli ulcer patients in Ghana. Phillips RO, Frimpong M, Sarfo SF, Kretschmer B, Beissner M, Debrah A, Amoako YA, Abass KM, Thompson W, Sarpong Duah M, Abotsi J, Adjei O, Fleischer B, Bretzel G, Wansbrough-Jones M, Jacobsen M. EMERGING INFECTIOUS DISEASES JOURNAL. PubMed

• Differential gene expression of activating Fcγ receptor classifies active tuberculosis regardless of human immunodeficiency virus status or ethnicity.CLINICAL MICROBIOLOGY AND INFECTION. Sutherland JS, Loxton AG, Haks MC, Kassa D, Ambrose L, Lee JS, Ran L, van Baarle D, Maertzdorf J, Howe R, Mayanja-Kizza H, Boom WH, Thiel BA, Crampin AC, Hanekom W, Ota MO, Dockrell H, WalzlG, Kaufmann SH, Ottenhoff TH; GCGH Biomarkers for TB consortium. u.a. Jacobsen M PubMed

• Are microRNAs suitable biomarkers of immunity to tuberculosis? Ueberberg B, Kohns M, Mayatepek E, Jacobsen M. MOLECULAR AND CELLULAR PEDIATRICS. PubMed