Research Group Bönner

Main research topics

  • Inflammation and Adaptation in Ischemic Heart Disease
  • Interorgan Communication

Current projects

  • Feasibility of 19F MRI for inflammation imaging after myocardial infarction in pigs
  • Effects on remote myocardium after infarction on the transcriptomic level
  • 19F MRI for the prediction of vascular events
  • Systemic interaction between ischemic brain and the heart

Collaborations

  • Prof. Dr. med. U. Flögel (CARID)
  • Prof. Dr. med. G. Klau (Algorithmische Bioinformatik)
  • Prof. Dr. med. K. Klingel (Tübingen)

Selected publikations

  • Gastl M, Behm P, Haberkorn S, Holzbach L, Veulemans V, Jacoby C, Schnackenburg B, Zeus T, Kelm M, Bönner F. Role of T2 mapping in left ventricular reverse remodeling after TAVR. Int J Cardiol. 2018 Sep 1;266:262-268
  • Spieker M, Katsianos E, Gastl M, Behm P, Horn P, Jacoby C, Schnackenburg B, Reinecke P, Kelm M, Westenfeld R, Bönner F. T2 mapping cardiovascular magnetic resonance identifies the presence of myocardial inflammation in patients with dilated cardiomyopathy as compared to endomyocardial biopsy. Eur Heart J Cardiovasc Imaging. 2018 May 1;19(5):574-582.
  • Spieker M, Haberkorn S, Gastl M, Behm P, Katsianos S, Horn P, Jacoby C, Schnackenburg B, Reinecke P, Kelm M, Westenfeld R, Bönner F. Abnormal T2 mapping cardiovascular magnetic resonance correlates with adverse clinical outcome in patients with suspected acute myocarditis. J Cardiovasc Magn Reson. 2017 Mar 29;19(1):38.
  • Bönner F, Spieker M, Haberkorn S, Jacoby C, Flögel U, Schnackenburg B, Horn P, Reinecke P, Neizel-Wittke M, Kelm M, Westenfeld R. Myocardial T2 Mapping Increases Noninvasive Diagnostic Accuracy for Biopsy-Proven Myocarditis. JACC Cardiovasc Imaging. 2016 Dec;9(12):1467-1469.
  • Bönner F, Merx MW, Klingel K, Begovatz P, Flögel U, Sager M, Temme S, Jacoby C, Salehi Ravesh M, Grapentin C, Schubert R, Bunke J, Roden M, Kelm M, Schrader J. Monocyte imaging after myocardial infarction with 19F MRI at 3 T: a pilot study in explanted porcine hearts. Eur Heart J Cardiovasc Imaging. 2015 Jun;16(6):612-20.
  • Bönner F, Janzarik N, Jacoby C, Spieker M, Schnackenburg B, Range F, Butzbach B, Haberkorn S, Westenfeld R, Neizel-Wittke M, Flögel U, Kelm M. Myocardial T2 mapping reveals age- and sex-related differences in volunteers. J Cardiovasc Magn Reson. 2015 Feb 6;17(1):9
  • Bönner F, Haberkorn SM, Fenk R, Kelm M, Balzer J. Primary cardiac sarcoma: a rare disease with rapid progression. Eur Heart J. 2015 Mar 14;36(11):698
  • Bönner F, Jacoby C, Temme S, Borg N, Ding Z, Schrader J, Flögel U. Multifunctional MR monitoring of the healing process after myocardial infarction. Basic Res Cardiol. 2014;109(5):430.
  • Bönner F, Borg N, Jacoby C, Temme S, Ding Z, Flögel U, Schrader J. Ecto-5'-nucleotidase on immune cells protects from adverse cardiac remodeling. Circ Res. 2013 Jul 19;113(3):301-12.
  • Bönner F, Borg N, Burghoff S, Schrader J. Resident cardiac immune cells and expression of the ectonucleotidase enzymes CD39 and CD73 after ischemic injury. PLoS One. 2012;7(4):e34730.
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