- Reiche, M. E., den Toom, M., Willemsen, L., van Os, B., Gijbels, M., Gerdes, N., Aarts, S., & Lutgens, E. (2019). Deficiency of T cell CD40L has minor beneficial effects on obesity-induced metabolic dysfunction. BMJ open diabetes research & care, 7(1), e000829. doi.org/10.1136/bmjdrc-2019-000829
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936585/
Bianchini M, Duchêne J, Santovito D, Schloss MJ, Evrard M, Winkels H, Aslani M, Mohanta SK, Horckmans M, Blanchet X, Lacy M, von Hundelshausen P, Atzler D, Habenicht A, Gerdes N, Pelisek J, Ng LG, Steffens S, Weber C, Megens RTA. PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function. Sci Immunol. 2019;4(36):eaar3054. doi:10.1126/sciimmunol.aar3054
https://immunology.sciencemag.org/content/4/36/eaar3054
- Winkels H, Meiler S, Lievens D, Engel D, Spitz C, Burger C, Beckers L, Dandl A, Reim S, Ahmadsei M, Hartwig H, Holdt LM, Hristov M, Megens RT, Schmitt M, Biessen EA, Borst J, Faussner A, Weber C, Lutgens E, Gerdes N. CD27 co-stimulation increases the abundance of regulatory t cells and reduces atherosclerosis in hyperlipidemic mice. Eur Heart J. 2017, 38(48):3590-3599. (PMID: 29045618)
https://academic.oup.com/eurheartj/article/38/48/3590/4554905
- Winkels H, Meiler S, Smeets E, Lievens D, Engel D, Spitz C, Bürger C, Rinne P, Beckers L, Dandl A, Reim S, Ahmadsei M, Van den Bossche J, Holdt LM, Megens RT, Schmitt M, de Winther M, Biessen EA, Borst J, Faussner A, Weber C, Lutgens E, Gerdes N. CD70 limits atherosclerosis and promotes macrophage function. Thromb Haemost. 2017, 117(1):164-175. (PMID: 27786334)
https://www.thieme-connect.de/products/ejournals/abstract/10.1160/TH16-04-0318
- Gerdes N, Seijkens T, Lievens D, Kuijpers MJ, Winkels H, Projahn D, Hartwig H, Beckers L, Megens RT, Boon L, Noelle RJ, Soehnlein O, Heemskerk JW, Weber C, Lutgens E. Platelet CD40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes. Arterioscler Thromb Vasc Biol. 2016, 36(3):482-90. (PMID: 26821950)
https://www.ncbi.nlm.nih.gov/pubmed/26821950
- Wang J, Sun C, Gerdes N, Liu C, Liao M, Liu J, Shi MA, He A, Zhou Y, Sukhova GK, Chen H, Cheng M, Kuzuya M, Murohara T, Zhang J, Cheng X, Jiang M, Shull GE, Rogers S, Yang CL, Ke Q, Jelen S, Bindels R, Ellison DH, Jarolim P, Libby P, Shi GP. Interleukin 18 function in atherosclerosis requires both the interleukin 18 receptor and the Na-Cl co-transporter. Nat Med. 2015, 21(7):820-6. (PMID: 26099046)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554539/
- Strodthoff D, Lundberg AM, Agardh HE, Ketelhuth DF, Paulsson-Berne G, Arner P, Hansson GK, Gerdes N. Lack of Invariant Natural Killer T Cells Affects Lipid Metabolism in Adipose Tissue of Diet-Induced Obese Mice. Arterioscler Thromb Vasc Biol. 2013, 33(6):1189-96. (PMID: 23520162)
https://www.ahajournals.org/doi/10.1161/ATVBAHA.112.301105
- Klingenberg R*, Gerdes N*, Badeau RM, Gisterå A, Strodthoff D, Ketelhuth DF, Lundberg AM, Rudling M, Nilsson SK, Olivecrona G, Zoller S, Lohmann C, Lüscher TF, Jauhiainen M, Sparwasser T, Hansson GK. Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis. J Clin Invest. 2013, 123(3):1323-34. (PMID: 23426179) (* indicates equal contribution)
https://www.jci.org/articles/view/63891
- Gerdes N, Zhu L, Ersoy M, Hermansson A, Hjemdahl P, Hu H, Hansson GK, Li N. Platelets regulate CD4⁺ T-cell differentiation via multiple chemokines in humans. Thromb Haemost. 2011, 106(2):353-62. (PMID: 21655676)
https://www.ncbi.nlm.nih.gov/pubmed/21655676
- Zirlik A, Maier C, Gerdes N, MacFarlane LA, Soosairajah J, Bavendiek U, Arens I, Ernst S, Bassler N, Missiou A, Patko Z, Aikawa M, Schönbeck U, Bode C, Libby P, Peter K. CD40L mediates inflammation independently of CD40 by interaction with Mac-1. Circulation. 2007, 115(12):1571-1580. (PMID: 17372166)
https://www.ncbi.nlm.nih.gov/pubmed/17372166
- Schönbeck U, Gerdes N, Varo N, Reynolds RS, Horton DB, Bavendiek U, Robbie LA, Ganz P, Kinlay S, Libby P. Oxidized low-density lipoprotein augments and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors limit CD40 and CD40L expression in human vascular cells. Circulation 2002, 106(23):2888-2893. (PMID: 12460867)
https://www.ncbi.nlm.nih.gov/pubmed/12460867
- Gerdes N, Sukhova GK, Libby P, Young JL, Reynolds RS, Schönbeck U. Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for atherogenesis. J Exp Med. 2002, 195(2):245-257. (PMID: 11805151)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193607/