Research Group Jung

Main research topics

  • Cardiogenic shock
  • Microcirculation
  • Ischemia and reperfusion injury
  • Endothelial function, damage, metabolism and regeneration

Current projects

  • Cell-Cell interaction during ischemia and reperfusion injury
  • Role of circulating endothelial cell parameters as effectors of endothelial activation and damage
  • Regulation of microvascular perfusion and its clinical relevance in shock and critical disease

Collaborations (external)

  • Prof. Dr. med. H. Thiele (Leipzig Heart Center)
  • PD Dr. M. Franz/Prof. Dr. med. P. C. Schulze (Uni Jena)
  • Prof. Alexander Lauten (Charite Berlin)
  • PD Dr. M. Lichtenauer/Dr. B. Wernly (PMU Salzburg)
  • Prof. J. Pernow (Karolinska Institutet)

Selected publications

  • Jung C, Rafnsson A, Shemyakin A, Böhm F, Pernow J: Different Subpopulations of Endothelial Progenitor Cells and Circulating Apoptotic Progenitor Cells in Patients with Vascular Disease and Diabetes – Int J Cardiol. 2010 Sep 3;143(3):368-72
  • Jung C, Gonon AT, Sjöquist PO, Lundberg JO, Pernow J: Arginase inhibition mediates cardioprotection during ischaemia-reperfusion – Cardiovasc Res. 2010 Jan 1;85(1):147-54
  • Jung C, Fujita B, Lauten A, Kiehntopf M, Küthe F, Ferrari M, Figulla HR: Red blood cell distribution width as useful tool to predict long-term mortality in patients with chronic heart failure - Int J Cardiol. 2011 Nov 3;152(3):417-8
  • Jung C, Sörensson P, Saleh N, Arheden H, Rydén L, Pernow J:  Circulating endothelial and platelet derived microparticles reflect the size of myocardium at risk in patients with ST-elevation myocardial infarctionAtherosclerosis. 2012 Mar;221(1):226-31.
  • Jung C, Rafnsson A, Brismar K, Pernow J: Endothelial progenitor cells in relation to endothelin-1 and endothelin receptor blockade: A randomized, controlled trial. – Int J Cardiol. 2013 Sep 30;168(2): 1017-22
  • Shemyakin A, Kövamees O, Rafnsson A, Böhm F, Svenarud P, Settergren M, Jung C, Pernow J. Arginase Inhibition Improves Endothelial Function in Patients with Coronary Artery Disease and Type 2 Diabetes – Circulation. 2012 Dec 18;126(25):2943-50
  • Jung C, Fuernau G, de Waha S, Eitel I, Desch S, Schuler G, Figulla HR, Thiele H. Intraaortic balloon counterpulsation and microcirculation in cardiogenic shock complicating myocardial infarction: an IABP-SHOCK II substudy. Clin Res Cardiol. 2015 Aug;104(8):679-87
  • Yoon SH, Schmidt T, Bleiziffer S, Schofer N, Fiorina C, Munoz-Garcia AJ, Yzeiraj E, Amat-Santos IJ, Tchetche D, Jung C, Fujita B, Mangieri A, at al. Transcatheter Aortic Valve Replacement in Pure Native Aortic Valve Regurgitation. J Am Coll Cardiol. 2017 Dec 5;70(22):2752-2763
  • Guidet B, Flaatten H, Boumendil A, Morandi A, Andersen FH, Artigas A, Bertolini G, Cecconi M, Christensen S, Faraldi L, Fjølner J, Jung C, Marsh B, Moreno R, Oeyen S, Öhman CA, Pinto BB, Soliman IW, Szczeklik W, Valentin A, Watson X, Zafeiridis T, De Lange DW; VIP1 study group. Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit. Intensive Care Med. 2018 May 17
  • Jung C, Wernly B, Bjursell M, Wiseman J, Admyre T, Wikström J, Palmér M, Seeliger F, Lichtenauer M, Franz M, Frick C, Andersson AK, Elg M, Pernow J, Sjöquist PO, Bohlooly-Y M, Wang QD. Cardiac-Specific Overexpression of Oxytocin Receptor Leads to Cardiomyopathy in Mice. J Card Fail. 2018 May 23
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