Beteiligung des Teams an multizentrischen Registerstudien

Bereits seit vielen Jahren sind wir aktives Mitglied im deutschen Register “Diabetes-Patienten-Verlaufsdokumentation” (DPV), einem der weltweit größten Diabetesregister, an dem über 400 Zentren aus Deutschland und Österreich, aber auch aus der Schweiz und Luxemburg teilnehmen. Unser Team beteiligt sich sehr regelmäßig wissenschaftlich an Auswertungen aus dieser Datenbank und an der Verfassung von Manuskripten/Publikationen zu diesen Auswertungen. 

Insbesondere haben wir Projekte mitgestaltet zu psychosozialen Themen im Kontext des Typ 1 Diabetes, seltenen Diabetesformen, und deren Klassifikation/Therapie, sowie verschiedenenen Komorbiditäten des Diabetes. 

Projektbeteiligte

Prof. Dr. med. Thomas Meißner

Stellvertretender Direktor der Klinik
Facharzt für Kinder- und Jugendmedizin, Zusatzweiterbildung und Weiterbildungsbefugnis Kinder-Endokrinologie und -Diabetologie, Diabetologe DDG

Dr. med. Christina Reinauer

Wissenschaftliche Mitarbeiterin
FÄ für Kinder- u. Jugendmedizin, Zusatzweiterbildung Kinder-Endokrinologie und -Diabetologie, Päd. Ernährungsmedizinerin (DGKJ), Diabetologin (DDG)

Dr. med. Dr. rer. nat. Alena Welters

Oberärztin
Fachärztin für Kinder- und Jugendmedizin, Diabetologin DDG

Dr. med. Sebastian Kummer

Oberarzt
Facharzt für Kinder- und Jugendmedizin, Zusatzweiterbildung und Weiterbildungsbefugnis Kinder-Endokrinologie und -Diabetologie, Diabetologe DDG, Qualifikation zur fachgebundenen genetischen Beratung

Bisherige Publikationen
  • Trends in the incidence of type 1 diabetes and type 2 diabetes in children and adolescents in North Rhine-Westphalia, Germany, from 2002 to 2022
    Anna Stahl-Pehe, Christina Baechle, Stefanie Lanzinger, Michael S Urschitz, Christina Reinauer, Clemens Kamrath, Reinhard W Holl, Joachim Rosenbauer
  • Diabetes care and outcomes of pediatric refugees and migrants from Ukraine and Syria/Afghanistan with type 1 diabetes in German-speaking countries
    Marie Auzanneau, Christina Reinauer, Julian Ziegler, Sven Golembowski, Carine de Beaufort, Hannah Schöttler, Eva Hahn, Joaquina Mirza, Angela Galler, Michael Wurm, Reinhard W Holl
  • Mental disorders in children and adolescents with type 1 diabetes before and during the COVID-19 pandemic: results from the DPV registry
    Esther Müller-Godeffroy, Stefanie Schmid, Christina Reinauer, Angela Galler, Dörte Hilgard, Louise Marshall, Thomas Kapellen, Eggert Lilienthal, Kirsten Mönkemöller, Burkhard Brosig, Christine Prchla, Reinhard W Holl; DPV initiative
  • Frequency and characteristics of diabetes in lipodystrophies and insulin receptoropathies compared with type 1 and type 2: results from the multicenter DPV registry. 
    Kamrath C, Eckert A, Rami-Herhar B, Kummer S, Wabitsch M, Laubner K, Kopp F, Müther S, Mühldorfer S, Holl RW
  • Characterisation and clinical outcomes in children and adolescents with diabetes according to newly defined subgroups: a cohort study from the DPV registry
    Katharina Warncke, Alexander Eckert, Ezio Bonifacio, Peter Achenbach, Olga Kordonouri, Thomas Meissner, Ute Ohlenschläger, Walter Bonfig, Anette-G Ziegler, Reinhard W Holl
  • Clinical presentation and long-term outcome of patients with KCNJ11/ABCC8 variants: Neonatal diabetes or MODY in the DPV registry from Germany and Austria.
    Warncke K, Eckert A, Kapellen T, Kummer S, Raile K, Dunstheimer D, Grulich-Henn J, Woelfle J, Wenzel S, Hofer SE, Dost A, Holl RW
  • Clinical characteristics and cardiovascular risk profile in children and adolescents with latent autoimmune diabetes: Results from the German/Austrian prospective diabetes follow-up registry
    Alena Welters, Sascha R Tittel, Thomas Reinehr, Daniel Weghuber, Susanna Wiegand, Wolfram Karges, Clemens Freiberg, Thomas Meissner, Nanette C Schloot, Reinhard W Holl
  • Prevalence trends of type 1 and type 2 diabetes in children and adolescents in North Rhine-Westphalia, the most populous federal state in Germany, 2002-2020
    C Baechle, A Stahl-Pehe, N Prinz, T Meissner, C Kamrath, R W Holl, J Rosenbauer
  • Long-term trends of BMI and cardiometabolic risk factors among adults with type 1 diabetes: an observational study from the German/Austrian DPV registry  
    Alena Welters, Tittel SR, Laubner K, Laimer M, Tschöpe D, Mader JK, Merger S, Milek S, Kummer S,* Holl RW* *contributed equally
  • Non-suicidal self-injury in adolescents and young adults with type 1 diabetes: clinical characteristics from a German diabetes-patient registry (DPV)
    Alexander Eckert, Matthias Domhardt, Christina Reinauer, Gabriele Berger, Angela Galler, Andreas Böckmann, Martina Henn, Thomas Haak, Reinhard W Holl
  • Worse glycemic control, higher rates of diabetic ketoacidosis, and more hospitalizations in children, adolescents, and young adults with type 1 diabetes and anxiety disorders
    Angela Galler, Sascha R Tittel, Harald Baumeister, Christina Reinauer, Burkhard Brosig, Marianne Becker, Holger Haberland, Dörte Hilgard, Marcelus Jivan, Joaquina Mirza, Julia Schwab, Reinhard W Holl
  • Sex differences over time for glycemic control, pump use and insulin dose in patients aged 10-40 years with type 1 diabetes: a diabetes registry study
    Claudia Boettcher, Sascha R Tittel, Thomas Meissner, Bettina Gohlke, Rainer Stachow, Axel Dost, Sybille Wunderlich, Iris Lowak, Stefanie Lanzinger
  • Diabetes management in Wolcott-Rallison syndrome: analysis from the German/Austrian DPV database
    Alena Welters, Thomas Meissner, Katja Konrad, Clemens Freiberg, Katharina Warncke, Sylvia Judmaier, Olga Kordonouri, Michael Wurm, Matthias Papsch, Gisela Fitzke, Silke Christina Schmidt, Sascha R Tittel, Reinhard W Holl
  • Continuous Glucose Monitoring in Adults with Type 1 Diabetes: Real-World Data from the German/Austrian Prospective Diabetes Follow-Up Registry
    Dirk Sandig, Julia Grimsmann, Christina Reinauer, Andreas Melmer, Stefan Zimny, Michael Müller-Korbsch, Nicole Forestier, Andrej Zeyfang, Peter Bramlage, Thomas Danne, Thomas Meissner, Reinhard W Holl
  • Frequency and characteristics of rare MODY forms MODY 1 (HNF4A mutation) and MODY 5 (HNF1B mutation) - Analysis from the DPV database
    Warncke K*, Kummer S*, Raile K, Grulich-Henn J, Wölfle J, Steichen E, Prinz N, Holl RW. *contributed equally
  • Course of Disordered Eating Behavior in Young People With Early-Onset Type I Diabetes: Prevalence, Symptoms, and Transition Probabilities
    Christina Baechle, Annika Hoyer, Anna Stahl-Pehe, Katty Castillo, Thaddaeus Toennies, Lena M E Lindner, Christina Reinauer, Reinhard W Holl, Oliver Kuss, Joachim Rosenbauer
  • Characterization of diabetes following pancreatic surgery in patients with congenital hyperinsulinism
    Alena Welters, Thomas Meissner, Jürgen Grulich-Henn, Elke Fröhlich-Reiterer, Katharina Warncke, Klaus Mohnike, Oliver Blankenstein, Ulrike Menzel, Nicolin Datz, Esther Bollow, Reinhard W Holl
  • Cardivascular Risk Profile in Patients with Diabetes and Acromegaly or Cushing’s Disease – Analysis from the DPV Database
    Warncke K, Kummer S, Kann P, Badenhoop K, Bollow E, Hummel M, Zoicas F, Wernert S, Holl RW for the German/Austrian Diabetes Prospective follow-up initiative DPV
  • Lipoprotein-associated phospholipase A2 activity in obese adolescents with and without type 2 diabetes
    Julia Seyfarth, Thomas Reinehr, Annika Hoyer, Christina Reinauer, Christina Bächle, Beate Karges, Ertan Mayatepek, Michael Roden, Sabine E Hofer, Susanna Wiegand, Joachim Woelfle, Wieland Kiess, Joachim Rosenbauer, Reinhard W Holl, Thomas Meissner
  • Low prevalence of patients with mitochondrial disease in the German/Austrian DPV diabetes registry
    Christina Reinauer, Thomas Meissner, Michael Roden, Angelika Thon, Paul-Martin Holterhus, Holger Haberland, Elisabeth Binder, Wolfgang Marg, Esther Bollow, Reinhard Holl
  • Vascular risk factors in children, adolescents, and young adults with type 1 diabetes complicated by celiac disease: results from the DPV initiative
    Katharina Warncke, Susanne Liptay, Elke Fröhlich-Reiterer, Nicole Scheuing, Martin Schebek, Johannes Wolf, Tilman R Rohrer, Thomas Meissner, Reinhard W Holl
  • Overweight and Obesity Based on Four Reference Systems in 18,382 Paediatric Patients with Type 1 Diabetes from Germany and Austria
    M Flechtner-Mors, K O Schwab, E E Fröhlich-Reiterer, T M Kapellen, T Meissner, J Rosenbauer, R Stachow, R W Holl
  • Treatment of young patients with HNF1A mutations (HNF1A-MODY)
    K Raile, E Schober, K Konrad, A Thon, J Grulich-Henn, T Meissner, J Wölfle, N Scheuing, R W Holl; DPV Initiative the German BMBF Competence Network Diabetes Mellitus
  • Carbohydrate intake and insulin requirement in children, adolescents and young adults with cystic fibrosis-related diabetes: A multicenter comparison to type 1 diabetes
    Nicole Scheuing, Angelika Thon, Katja Konrad, Maria Bauer, Claudia Karsten, Thomas Meissner, Jochen Seufert, Eckhard Schönau, Christof Schöfl, Joachim Woelfle, Reinhard W Holl; German/Austrian Diabetes Prospective Documentation Initiative and the BMBF Competence Network Diabetes Mellitus
  • Current use of metformin in addition to insulin in pediatric patients with type 1 diabetes mellitus: an analysis based on a large diabetes registry in Germany and Austria
    Katja Konrad, Nicolin Datz, Ilse Engelsberger, Jürgen Grulich-Henn, Thomas Hoertenhuber, Burkhild Knauth, Thomas Meissner, Susanna Wiegand, Joachim Woelfle, Reinhard W Holl; German/Austrian DPV Initiative
  • Impact of regular physical activity on blood glucose control and cardiovascular risk factors in adolescents with type 2 diabetes mellitus--a multicenter study of 578 patients from 225 centres
    A Herbst, T Kapellen, E Schober, C Graf, T Meissner, R W Holl; DPV-Science-Initiative
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