Originalpublikationen 2008


Bidmon, H. J., Görg, B., Palomero-Gallagher, N., Schleicher, A., Häussinger, D., Speckmann, E. J. and Zilles, K. (2008)
Glutamine synthetase becomes nitrated and its activity is reduced during repetitive seizure activity in the pentylentetrazole model of epilepsy.
Epilepsia, 49: 1733-1748. (PubMed)

Bode, J. G., Brenndörfer, E. D. and Häussinger, D. (2008)
Hepatitis C virus (HCV) employs multiple strategies to subvert the host innate antiviral response.
Biol Chem, 389: 1283-1298. (PubMed)

Boy, C., Meyer, P. T., Kircheis, G., Holschbach, M. H., Herzog, H., Elmenhorst, D., Kaiser, H. J., Coenen, H. H., Häussinger, D., Zilles, K. and Bauer, A. (2008)
Cerebral A1 adenosine receptors (A1AR) in liver cirrhosis.
Eur J Nucl Med Mol Imaging, 35: 589-597. (PubMed)

Cornberg, M., Protzer, U., Dollinger, M. M., Petersen, J., Wedemeyer, H., Berg, T., Jilg, W., Erhardt, A., Wirth, S., Schirmacher, P., Fleig, W. E. and Manns, M. P. (2008)
The German guideline for the management of hepatitis B virus infection: short version.
J Viral Hepat, 15 Suppl 1: 1-21. (PubMed)

Cornely, O. A., Böhme, A., Reichert, D., Reuter, S., Maschmeyer, G., Maertens, J., Buchheidt, D., Paluszewska, M., Arenz, D., Bethe, U., Effelsberg, J., Lövenich, H., Sieniawski, M., Haas, A., Einsele, H., Eimermacher, H., Martino, R., Silling, G., Hahn, M., Wacker, S., Ullmann, A. J. and Karthaus, M. (2008)
Risk factors for breakthrough invasive fungal infection during secondary prophylaxis.
J Antimicrob Chemother, 61: 939-946. (PubMed)

Falk, S., Wurdak, H., Ittner, L. M., Ille, F., Sumara, G., Schmid, M. T., Draganova, K., Lang, K. S., Paratore, C., Leveen, P., Suter, U., Karlsson, S., Born, W., Ricci, R., Götz, M. and Sommer, L. (2008)
Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion.
Cell Stem Cell, 2: 472-483. (PubMed)

Görg, B., Qvartskhava, N., Keitel, V., Bidmon, H. J., Selbach, O., Schliess, F. and Häussinger, D. (2008)
Ammonia induces RNA oxidation in cultured astrocytes and brain in vivo.
Hepatology, 48: 567-579. (PubMed)

Gotthardt, D., Runz, H., Keitel, V., Fischer, C., Flechtenmacher, C., Wirtenberger, M., Weiss, K. H., Imparato, S., Braun, A., Hemminki, K., Stremmel, W., Ruschendorf, F., Stiehl, A., Kubitz, R., Burwinkel, B., Schirmacher, P., Knisely, A. S., Zschocke, J. and Sauer, P. (2008)
A mutation in the canalicular phospholipid transporter gene, ABCB4, is associated with cholestasis, ductopenia, and cirrhosis in adults.
Hepatology, 48: 1157-1166. (PubMed)

Graf, D., Haselow, K., Munks, I., Bode, J. G. and Häussinger, D. (2008)
Caspase-mediated cleavage of the signal-transducing IL-6 receptor subunit gp130.
Arch Biochem Biophys, 477: 330-338. (PubMed)

Gruner, B., Kratzer, W., Buttenschon, K., Kern, P. and Reuter, S. (2008)
A case of sporadic Echinococcus granulosus infection originating from Southern Germany.
Infection, 36: 78-81. (PubMed)

Häussinger, D. (2008)
Osmosensing and osmosignaling in the liver.
Wien Med Wochenschr, 158: 549-552. (PubMed)

Häussinger, D. and Schliess, F. (2008)
Pathogenetic mechanisms of hepatic encephalopathy.
Gut, 57: 1156-1165. (PubMed)

Heikenwalder, M., Prinz, M., Zeller, N., Lang, K. S., Junt, T., Rossi, S., Tumanov, A., Schmidt, H., Priller, J., Flatz, L., Rulicke, T., Macpherson, A. J., Hollander, G. A., Nedospasov, S. A. and Aguzzi, A. (2008)
Overexpression of lymphotoxin in T cells induces fulminant thymic involution.*
Am J Pathol, 172: 1555-1570. (PubMed)

Ittner, L. M., Schwerdtfeger, K., Kunz, T. H., Muff, R., Husmann, K., Grimm, C., Hafezi, F., Lang, K. S., Kurrer, M. O., Götz, J., Born, W. and Fischer, J. A. (2008)*
Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma.
Clin Sci, 114: 49-58. (PubMed)

Johansen, P., Storni, T., Rettig, L., Qiu, Z., Der-Sarkissian, A., Smith, K. A., Manolova, V., Lang, K. S., Senti, G., Mullhaupt, B., Gerlach, T., Speck, R. F., Bot, A. and Kundig, T. M. (2008)*
Antigen kinetics determines immune reactivity.
Proc Natl Acad Sci U S A, 105: 5189-5194. (PubMed)

Karthe, J., Tessmann, K., Li, J., Machida, R., Daleman, M., Häussinger, D. and Heintges, T. (2008)
Specific targeting of hepatitis C virus core protein by an intracellular single-chain antibody of human origin.
Hepatology, 48: 702-712. (PubMed)

Keitel, V., Donner, M., Winandy, S., Kubitz, R. and Häussinger, D. (2008)
Expression and function of the bile acid receptor TGR5 in Kupffer cells.
Biochem Biophys Res Commun, 372: 78-84. (PubMed)

Keitel, V., Kubitz, R. and Häussinger, D. (2008)
Endocrine and paracrine role of bile acids.
World J Gastroenterol, 14: 5620-5629. (PubMed)

Klionsky, D. J.et al. (2008)
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.
Autophagy, 4: 151-175. (PubMed)

Kordes, C., Sawitza, I. and Häussinger, D. (2008)
Canonical Wnt signaling maintains the quiescent stage of hepatic stellate cells.
Biochem Biophys Res Commun, 367: 116-123. (PubMed)

Lang, P. A., Contaldo, C., Georgiev, P., El-Badry, A. M., Recher, M., Kurrer, M., Cervantes-Barragan, L., Ludewig, B., Calzascia, T., Bolinger, B., Merkler, D., Odermatt, B., Bader, M., Graf, R., Clavien, P. A., Hegazy, A. N., Lohning, M., Harris, N. L., Ohashi, P. S., Hengartner, H., Zinkernagel, R. M. and Lang, K. S. (2008)*
Aggravation of viral hepatitis by platelet-derived serotonin.
Nat Med, 14: 756-761. (PubMed)

Langmann, P., Heinz, W., Klinker, H., Schirmer, D., Guhl, C., Leyh, M. and Winzer, R. (2008)
High performance liquid chromatographic method for the determination of HIV-1 protease inhibitor tipranavir in plasma of patients during highly active antiretroviral therapy.
Eur J Med Res, 13: 52-58. (PubMed)

Langmann, P., Hubert, C., Heinz, W., Trein, A., Schnaitmann, E., Leyh, M., Klinker, H. and Winzer, R. (2008)
Safety of long-term lopinavir plasma-levels in patients with liver disease.
Eur J Med Res, 13: 205-208. (PubMed)

Langmann, P., Winzer, R., Schirmer, D., Heinz, W., Leyh, M., Guhl, C., Weissbrich, B. and Klinker, H. (2008)
Low trough levels of tipranavir in a combination antiretroviral therapy of tipranavir/ritonavir and tenofovir require therapeutic drug monitoring.
Eur J Med Res, 13: 469-471. (PubMed)

Llovet, J. M., Ricci, S., Mazzaferro, V., Hilgard, P., Gane, E., Blanc, J. F., de Oliveira, A. C., Santoro, A., Raoul, J. L., Forner, A., Schwartz, M., Porta, C., Zeuzem, S., Bolondi, L., Greten, T. F., Galle, P. R., Seitz, J. F., Borbath, I., Häussinger, D., Giannaris, T., Shan, M., Moscovici, M., Voliotis, D. and Bruix, J. (2008)
Sorafenib in advanced hepatocellular carcinoma.
N Engl J Med, 359: 378-390. (PubMed)

Lohning, M., Hegazy, A. N., Pinschewer, D. D., Busse, D., Lang, K. S., Hofer, T., Radbruch, A., Zinkernagel, R. M. and Hengartner, H. (2008)
Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors.*
J Exp Med, 205: 53-61. (PubMed)

Mallach, S., Ramp, U., Erhardt, A., Schmitt, M. and Häussinger, D. (2008)
An uncommon cause of gastro-duodenal ulceration.
World J Gastroenterol, 14: 2593-2595. (PubMed)

Mannack, G., Graf, D., Donner, M. M., Richter, L., Görg, B., Vom Dahl, S., Häussinger, D. and Schliess, F. (2008)
Taurolithocholic acid-3 sulfate impairs insulin signaling in cultured rat hepatocytes and perfused rat liver.
Cell Physiol Biochem, 21: 137-150. (PubMed)

Müller-Stöver, I., Verweij, J. J., Hoppenheit, B., Göbels, K., Häussinger, D. and Richter, J. (2008)
Plasmodium malariae infection in spite of previous anti-malarial medication.
Parasitol Res, 102: 547-550. (PubMed)

Münk, C., Beck, T., Zielonka, J., Hotz-Wagenblatt, A., Chareza, S., Battenberg, M., Thielebein, J., Cichutek, K., Bravo, I. G., O'Brien, S. J., Lochelt, M. and Yuhki, N. (2008)
Functions, structure, and read-through alternative splicing of feline APOBEC3 genes.
Genome Biol, 9: R48. (PubMed)

Oette, M., Reuter, S. and Häussinger, D. (2008)
Behandlung hochlethaler Infektionen.
Rheinisches Ärzteblatt, 8: 21-22. 

Pauli, E. K., Schmolke, M., Wolff, T., Viemann, D., Roth, J., Bode, J. G. and Ludwig, S. (2008)
Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression.
PLoS Pathog, 4: e1000196. (PubMed)

Reinehr, R. and Häussinger, D. (2008)
CD95 ligation and intracellular membrane flow.
Biochem J, 413: e11-12. (PubMed)

Reinehr, R., Sommerfeld, A. and Häussinger, D. (2008)
CD95 ligand is a proliferative and antiapoptotic signal in quiescent hepatic stellate cells.
Gastroenterology, 134: 1494-1506. (PubMed)

Reinehr, R., Sommerfeld, A., Keitel, V., Grether-Beck, S. and Häussinger, D. (2008)
Amplification of CD95 activation by caspase 8-induced endosomal acidification in rat hepatocytes.
J Biol Chem, 283: 2211-2222. (PubMed)

Reuter, S., Gruner, B., Buck, A. K., Blumstein, N., Kern, P. and Reske, S. N. (2008)
Long-term follow-up of metabolic activity in human alveolar echinococcosis using FDG-PET.
Nuklearmedizin, 47: 147-152. (PubMed)

Richter, J., Lux, J., Reinecke, P. and Muller-Mattheis, V. (2008)
Of flukes and fistulae.
Lancet, 371: 1308. (PubMed)

Richter, J., Schmitt, M., Müller-Stöver, I., Göbels, K. and Häussinger, D. (2008)
Sonographic detection of subcutaneous fly larvae in human myiasis.
J Clin Ultrasound, 36: 169-173. (PubMed)

Sagir, A., Adams, O., Oette, M., Vogel, M., Kupfer, B., Emmelkamp, J., Rockstroh, J. and Häussinger, D. (2008)
SEN Virus infection in HIV/HCV coinfected patients.
Eur J Med Res, 13: 495-499. (PubMed)

Sagir, A., Erhardt, A., Schmitt, M. and Häussinger, D. (2008)
Transient elastography is unreliable for detection of cirrhosis in patients with acute liver damage.
Hepatology, 47: 592-595. (PubMed)

Schmelzle, M., Matthaei, H., Tustas, R. Y., Schmitt, M., Müller-Mattheis, V., Linhart, W., Eisenberger, C. F., Knoefel, W. T. and Esch, J. S., 2nd (2008)
Abdominal perforation after rupture of a diamond-studded wire: a case report.
Cases J, 1: 307. (PubMed)

Shah, N. J., Neeb, H., Kircheis, G., Engels, P., Häussinger, D. and Zilles, K. (2008)
Quantitative cerebral water content mapping in hepatic encephalopathy.
Neuroimage, 41: 706-717. (PubMed)

Speckmann, B., Walter, P. L., Alili, L., Reinehr, R., Sies, H., Klotz, L. O. and Steinbrenner, H. (2008)
Selenoprotein P expression is controlled through interaction of the coactivator PGC-1alpha with FoxO1a and hepatocyte nuclear factor 4alpha transcription factors.
Hepatology, 48: 1998-2006. (PubMed)

Timmermann, L., Butz, M., Gross, J., Ploner, M., Sudmeyer, M., Kircheis, G., Häussinger, D. and Schnitzler, A. (2008)
Impaired cerebral oscillatory processing in hepatic encephalopathy.
Clin Neurophysiol, 119: 265-272. (PubMed)

Vermeulen, T., Görg, B., Vogl, T., Wolf, M., Varga, G., Toutain, A., Paul, R., Schliess, F., Häussinger, D. and Häberle, J. (2008)
Glutamine synthetase is essential for proliferation of fetal skin fibroblasts.
Arch Biochem Biophys, 478: 96-102. (PubMed)

Wang, K., Mahmud, H., Foller, M., Biswas, R., Lang, K. S., Bohn, E., Götz, F. and Lang, F. (2008)
Lipopeptides in the triggering of erythrocyte cell membrane scrambling.
Cell Physiol Biochem, 22: 381-386. (PubMed)

Warskulat, U., Brookmann, S., Felsner, I., Brenden, H., Grether-Beck, S. and Häussinger, D. (2008)
Ultraviolet A induces transport of compatible organic osmolytes in human dermal fibroblasts.
Exp Dermatol, 17: 1031-1036. (PubMed)

Wisbauer, M., Schmitt, M., Mayatepek, E. and Hoehn, T. (2008)
Akzidentelle Kaliumpermanganatverätzung.
Monatsschrift Kinderheilkunde, 156: 1100-1103. (PubMed)

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